http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
이정하,엄성환,EunHyeLee,Yeoun-Joong Jung,Hyo-Jung Kim,Mi-Ra Jo,Kwang-TaeSon,Hee-Jung Lee,Ji-HoeKim,Myung-Suk Lee,김영목 한국조류학회I 2014 ALGAE Vol.29 No.1
To develop effective and safe acne vulgaris therapies with a continuing demand for new solutions, we investigated unique efficacy of an antibacterial agent from marine brown alga Eisenia bicyclis in treating acne vulgaris. The methanolic extract of E. bicyclis exhibited potential antibacterial activity against acne-related bacteria. The ethyl acetate fraction showed the strongest antibacterial activity against the bacteria among solvent fractions. Six compounds (1-6), previously isolated from the ethyl acetate fraction of E. bicyclis, were evaluated for antibacterial activity against acne-related bacteria. Among them, compound 2 (fucofuroeckol-A [FF]) exhibited the highest antibacterial activity against acne-related bacteria with a minimum inhibitory concentration (MIC) ranging from 32 to 128 μg mL-1. Furthermore, FF clearly reversed the high-level erythromycin and lincomycin resistance of Propionibacterium acnes. The MIC values of erythromycin against P. acnes were dramatically reduced from 2,048 to 1.0 μg mL-1 in combination with MIC of FF (64 μg mL-1). The fractional inhibitory concentration indices of erythromycin and lincomycin were measured from 0.500 to 0.751 in combination with 32 or 64 μg mL-1 of FF against all tested P. acnes strains, suggesting that FF-erythromycin and FF-lincomycin combinations exert a weak synergistic effect against P. acnes. The results of this study suggest that the compounds derived from E. bicyclis can be a potential source of natural antibacterial agents and a pharmaceutical component against acnerelated bacteria.
Behçet’s Disease with Deep Vaginal Ulcer Diagnosed for the First Time during Pregnancy
( Eun Hye Lee ),( Tae Kyung Lee ),( Joonho Lee ) 대한주산의학회 2019 Perinatology Vol.30 No.2
Behçet’s disease is a chronic multisystem inflammatory disease characterized by recurrent oral ulcer, genital ulcer and ocular inflammation. It affects mainly young adults ranging from twenties to forties, so the relationship between Behçet’s disease and pregnancy has been investigated in women during reproductive ages. In pregnant women, genital ulcers arise from infectious and noninfectious causes. We report a case of a Behçet’s disease with deep vaginal ulcer diagnosed for the first time during pregnancy.
Eunhye Lee,Inkyeoung Kim 대한말초신경학회 2016 The Nerve Vol.2 No.2
Acute visual loss resulting from an uncomplicated cranioplasty is rare. A 52-year-old man presented with computed tomography (CT)-proven acute subdural hematoma in the right frontotemporoparietal area. The patients got a standard craniotomy in supine position. But on postoperative day 24, he was diagnosed postoperative epidural and subdural empyema. The patient underwent infected bone flap removal and evacuation of epidural and subdural empyema. Four months later, he got right frontotemporoparietal cranioplasty with artificial bone (Medpor) after controlling of infection. But on postoperative day 15, he complained of inability to see with his right eye. Brain and orbital CT, magnetic resonance imaging scan performed postoperatively did not show any new intracranial or intraorbital pathology. There were not any adverse events such as excessive pressure placed on the eyeball or bulky retraction of frontal skin flap. Visual evoked potential revealed prechiasmatic lesion. Fundoscopy showed slightly pallor optic disc of right side. The patient’s vision in the right eye remained no light perception permanently. The reason and pathophysiology of the mechanism of this complication should be discussed through reporting more cases.
( Eun Hye Lee ),( Ah Young Leem ),( Sang Hoon Lee ),( Joo Han Song ),( Song Yee Kim ),( Kyung Soo Chung ),( Ji Ye Jung ),( Moo Suk Park ),( Young Sam Kim ),( Joon Chang ),( Young Ae Kang ) 대한결핵 및 호흡기학회 2018 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.126 No.-
Background: The prevalence of nontuberculous mycobacteria lung disease (NTM-LD) is increasing worldwide. However, there is limited information about the NTM-LD of young age people. Methods: Patients diagnosed with NTM-LD at severance hospital between January 2006 and December 2016 were retrospectively reviewed. Clinical characteristics and microbiologic features of patients under 40 years were compared with patients over 40 years. Results: Total 906 patients were identified NTM-LD. Of these, 29 patients (3.2%) were under 40 years of age (young age group) and the remaining 877 were over 40 years of age (old age group). Mean age of the two groups were 32 (IQR 24-33) and 64 (IQR 56-72), respectively. Female was predominant in both groups and about half of the patients had a history of tuberculosis (51.7% vs.51.5%, p=0.984). 7 patients (24.1%) of the young age group had malignancy history and among them, 6 patients were hematologic cancer who subsequently received bone marrow transplantation. The proportion of the nodular bronchiectatic form of NTM-LD is significantly higher in old age group (67.5%) compared to young age group (31.0%) (p=<0.001). M.avium complex (MAC) was the most common etiologic organism in both groups, however, it was less common in the young age group (44.8% vs. 65.3%, p=0.023). Identification of M.abscessus complex (MABC) was higher in young age group although statistically insignificant (24.1% vs. 17.0%, p=0.318). Conclusion: This study could help to better understand the characteristics and microbial features of NTM-LD of young age people.
Two cases of tufted angioma treated with intralesional bleomycin injection
( Eun Hye Lee ),( Hyun Ji Lee ),( Jun Young Kim ),( Yong Hyun Jang ),( Weon Ju Lee ),( Seok-jong Lee ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1
Tufted angioma (TA) is a rare, benign vascular tumor that typically occurs during infancy or early childhood. Various treatment modalities such as surgery, prednisolone or sirolimus have been attempted, but there has been no reported case of sclerotherapy to treat TA successfully. Based on recent report of the effectiveness of bleomycin in early-stage arteriovenous malformation (AVM), we report two cases of application to treatment of bleomycin intralesional injection (ILI) to TA similar to early-stage AVM. The first is a 9-year-old boy who presented with erythematous plaques and papules on right leg since 1-month-old. The other is a 29-year-old male who presented with dusky brown patch and erythematous indurated papules on left anterior neck for 10 years. They had a history of receiving laser therapy several times before visiting our hospital, with no effect. Skin biopsies were performed and confirmed the diagnosis with TA. Doppler USG demonstrated there were arterial fast flows similar to early-stage AVM. So, we attempted to treat with bleomycin ILI several times, resulting in reducing lesion thickness and improvement of surface irregularities without side effects such as skin necrosis. The results were confirmed by clinical and imaging findings. Through these 2 cases, we suggest that bleomycin ILI as one of an effective and safe treatment option for intractable TA.