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High-Strength Chemical-Vapor–Deposited Graphene and Grain Boundaries
Lee, Gwan-Hyoung,Cooper, Ryan C.,An, Sung Joo,Lee, Sunwoo,van der Zande, Arend,Petrone, Nicholas,Hammerberg, Alexandra G.,Lee, Changgu,Crawford, Bryan,Oliver, Warren,Kysar, Jeffrey W.,Hone, James American Association for the Advancement of Scienc 2013 Science Vol.340 No.6136
<P><B>Graphene Staying Strong</B></P><P>Although exfoliated graphene can be extremely strong, it is produced on too small a scale for materials application. Graphene can be produced on a more practical scale by chemical vapor deposition, but the presence of grain boundaries between crystallites apparently weakens the material. <B>Lee <I>et al.</I></B> (p. 1073) show that postprocessing steps during the removal of the graphene sheets can oxidize the grain boundaries and weaken them. If these steps are avoided, the material is comparable in strength to exfoliated graphene.</P>
The Present Condition and Outlook of Hydrogen Industry in Alberta, Canada
Bryan Moon(문상호),Wonsuk Lee(이원석),Youngsoo Lee(이영수) 한국가스학회 2021 한국가스학회지 Vol.25 No.1
한국의 수소경제 활성화 로드맵에 의하면 2040년 526만톤의 연간 수소공급이 필요하며 이 중 해외 생산부분이 50%를 담당해야 할 것으로 설정하였으나 부생, 추출, 수전해 방식의 수소공급이 원활하지 않을 경우 해외 생산 비중이 당초 계획보다 증가될 수 있다. 따라서 국외 생산분에 대해 다양한 공급원의 확보가 필수적이며, 본 기술보고에서는 주요 공급후보국인 캐나다의 수소생산/수송 정책, 현황, 향후 전망에 대해 살펴보고 가장 현실적인 수소공급 방법으로 여겨지는 블루수소 프로젝트의 사례를 소개하고자 한다. Based on Korea’s Hydrogen Economy Activation Roadmap, an annual supply of 5.26 million tonnes of hydrogen is required by 2040. But if the hydrogen production from byproduct, extraction, and electrolysis of water is not able to meet the target which is 50% of total production, it would be necessary to increase the portion of imported hydrogen. Therefore, it is essential to secure a variety of sources for overseas production. In this technical report, hydrogen production/transportation policies, current condition, and future prospects of Canada, a major supply candidate, is examined and an example of blue hydrogen project which is considered the most realistic hydrogen supply method is introduced.
Youngwoo Bryan Yoon,Minah Kim,Junhee Lee,Kang Ik K,Cho,Seoyeon Kwak,Tae Young Lee,Jun Soo Kwon 대한신경정신의학회 2019 PSYCHIATRY INVESTIGATION Vol.16 No.3
We aim to investigate the effect of fronto-temporal transcranial direct current stimulation (tDCS) on the interactions among functional networks and its association with psychotic symptoms. In this pilot study, we will determine possible candidate functional networks and an adequate sample size for future research. Seven schizophrenia patients with treatment-refractory auditory hallucinations underwent tDCS twice daily for 5 days. Resting-state fMRI data and measures of the severity of psychotic symptoms were acquired at baseline and after completion of the tDCS sessions. At baseline, decreased functional network interaction was negatively correlated with increased hallucinatory behavior. After tDCS, the previously reduced functional network connectivity significantly increased. Our results showed that fronto-temporal tDCS could possibly remediate aberrant hallucination-related functional network interactions in patients with schizophrenia.
Integrated genomic analysis of recurrence-associated small non-coding RNAs in oesophageal cancer
Jang, Hee-Jin,Lee, Hyun-Sung,Burt, Bryan M,Lee, Geon Kook,Yoon, Kyong-Ah,Park, Yun-Yong,Sohn, Bo Hwa,Kim, Sang Bae,Kim, Moon Soo,Lee, Jong Mog,Joo, Jungnam,Kim, Sang Cheol,Yun, Ju Sik,Na, Kook Joo,Cho BMJ Publishing Group Ltd 2017 Gut Vol.66 No.2
<P>Conclusion We developed an easy-to-use prognostic model with three sncRNAs as robust prognostic markers for postoperative recurrence of ESCC. We anticipate that such a stratified and systematic, tumour-specific biological approach will potentially contribute to significant improvement in ESCC treatment.</P>
Kim, Woo‐,Young,Prudkin, Ludmila,Feng, Lei,Kim, Edward S.,Hennessy, Bryan,Lee, Ju‐,Seog,Lee, J. Jack,Glisson, Bonnie,Lippman, Scott M.,Wistuba, Ignacio I.,Hong, Waun Ki,Lee, Ho‐,Youn Wiley Subscription Services, Inc., A Wiley Company 2012 Cancer Vol.118 No.16
<P><B>Abstract</B></P><P><B>BACKGROUND:</B></P><P>Most patients with nonsmall cell lung cancer (NSCLC) have responded poorly to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs). The authors investigated the involvement of insulinlike growth factor 1 receptor (IGF‐1R) signaling in primary resistance to EGFR TKIs and the molecular determinants of resistance to IGF‐1R TKIs.</P><P><B>METHODS:</B></P><P>Phosphorylated IGF‐1R/insulin receptor (pIGF‐1R/IR) was immunohistochemically evaluated in an NSCLC tissue microarray. The authors analyzed the antitumor effects of an IGF‐1R TKI (PQIP or OSI‐906), either alone or in combination with a small‐molecular inhibitor (PD98059 or U0126) or with siRNA targeting <I>K‐Ras</I> or mitogen‐activated protein kinase/extracellular signal‐regulated kinase kinase (MEK), in vitro and in vivo in NSCLC cells with variable histologic features and <I>EGFR</I> or <I>K‐Ras</I> mutations.</P><P><B>RESULTS:</B></P><P>pIGF‐1R/IR expression in NSCLC specimens was associated with a history of tobacco smoking, squamous cell carcinoma histology, mutant <I>K‐Ras</I>, and wild‐type (WT) <I>EGFR</I>, all of which have been strongly associated with poor response to EGFR TKIs. IGF‐1R TKIs exhibited significant antitumor activity in NSCLC cells with WT EGFR and WT <I>K‐Ras</I> but not in those with mutations in these genes. Introduction of mutant <I>K‐Ras</I> attenuated the effects of IGF‐1R TKIs on NSCLC cells expressing WT <I>K‐Ras</I>. Conversely, inactivation of MEK restored sensitivity to IGF‐TKIs in cells carrying mutant <I>K‐Ras</I>.</P><P><B>CONCLUSIONS:</B></P><P>The mutation status of both <I>EGFR</I> and <I>K‐Ras</I> could be a predictive marker of response to IGF‐1R TKIs. Also, MEK antagonism can abrogate primary resistance of NSCLC cells to IGF‐1R TKIs. Cancer 2012. © 2012 American Cancer Society.</P>
Multi-Spectral Reflectance of Warm-Season Turfgrasses as Influenced by Deficit Irrigation
Lee, Joon-Hee,Trenholm, Laurie. E.,Unruh, J. Bryan Turfgrass Society of Korea 2008 한국잔디학회지 Vol.22 No.1
Multi-spectral radiometer (MSR)를 사용한 리모트 센싱 기술이 향 후 잔디의 건조스트레스를 감지할 수 있는 도구로 사용될 수 있다. 본 연구의 목적은 네가지 각기 다른 조건의 건조스트레스를 받은 난지형 잔디의 잎에서 반사되는 Reflectance와 토양수분, 비주얼 잔디상태, 엽록소 함량, 광합성 등을 측정하여 각 factor간의 상관관계를 조사했으며 본 연구를 통해 모든 factor가 MSR 데이터와 질은 상관관계를 가지고 있었다. 또한 Reflectance 민감도는Visual spectral region보다 Infrared spectral region에서 더 높음을 알 수 있었다. 모든 결과를 종합해 볼 때 Multi-spectral radiometer (MSR)은 잔디의 건조상태를 미리 예측할 수 있는 도구로 사용될 수 있음을 확인할 수 있었다. 이 기술의 자료를 활용하게 된다면 향 후 MSR이 부착된 기구(Balloon)를 이용한 필드 스터디 연구로 확대될 수 있을 것이다. Remote sensing using multispectral radiometry may be a useful tool to detect drought stress in turf. The objective of this research was to investigate the correlation between drought stress and multispectral reflectance (MSR) from the turf canopy. St. Augustinegrass (Stenotaphrum secundatum[Walt.] Kuntze.) cultivars 'Floratam' and 'Palmetto', 'SeaIsle 1' seashore paspalum Paspalum vaginatum Swartz.), 'Empire' zoysiagrass (Zoysia japonica Steud.), and 'Pensacola' bahiagrass (Paspalum notatumFlugge) were established in lysimeters in the University of Florida Envirotron greenhouse facility in Gainesville. Irrigation was applied at 100%, 80%, 60%, or 40% of evapotranspiration (ET). Weekly evaluations included: a) shoot quality, leaf rolling, leaf firing b) soil moisture, chlorophyll content index; c) photosynthesis and d) multispectral reflectance. All the measurements were correlated with MSR data. Drought stress affected the infrared spectral region more than the visible spectral region. Reflectance sensitivity to water content of leaves was higher in the infrared spectral region than in the visible spectral region. Grasses irrigated at 100% and 80% of ET had no differences in normalized difference vegetation indices (NDVI), leaf area index (LAI), and stress indices. Grasses irrigated at 60% and 40% of ET had differences in NDVI, LAI, and stress indices. All measured wavelengths except 710nm were highly correlated (P < 0.0001) with turf visual quality, leaf firing, leaf rolling, soil moisture, chlorophyll content index, and photosynthesis. MSR could detect drought stress from the turf canopy.