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      • KCI등재

        민들레 추출액 농도에 따른 민들레 코팅쌀밥의 품질에 관한 연구

        유경미,이연경,김세희,황인경,이부용,김성수,홍희도,김영찬 한국조리과학회 2005 한국식품조리과학회지 Vol.21 No.1

        Washed rice was coated by spraying aqueous dandelion (Taraxacum officinale) extracts at 20, 30, 40 'Brix and dried at room temperature. The coating procedure was conducted 5 mL/min for 10min. Property changes in the dandelion coated rice and un-coated cooked rice were observed during 2 days of storage. Increasing the coating concentration was associated with lower color values (L, a value) and moisture contents. Sensory and texture properties generally decreased in the cooked rice coated with dandelion more than the control (non-coated rice). But, D-20(20 °Brix of the dandelion concentration) resulted in better textural properties and s ensnry scores for hardness and overall acceptability in cooked rice. Compared to the control, the washed rice roated with 20 °Brix for 0 and 2 days showed better quality in sensory activities, a lower gel consistency and better textural activities. It was concluded that the optimum coating ration of rice and added dandelion extract for cooking were 20 °Brix and 5% respectively, in proportion to the total weight of raw rice.

      • KCI등재후보

        사망진단서(사체검안서) 상의 선행사인으로부터 사망통계의 원사인이 선정되는 비율 : 3개 대학병원에서 교부된 사망진단서를 중심으로

        박우성,박석건,정철원,김우철,탁우택,김부연,서순원,김광환,서진숙,부유경 한국의료QA학회 2004 한국의료질향상학회지 Vol.11 No.1

        Background : To exatnine the problems intolved in writing practice of death certificates, we cotnpated the determination of underlying cause of death for wital statistics using recorded underlying cause of death in issued death statistics. Methods : We collected 688 rnortality certificates issue in year of 2,000 from 3 university hospitals. And we also collected vital statistics from ministry of statistics. The causes of death were coded by experienced medical record wpecialists. And causes of death determined at ministry of statistics for national vita statistics were mapped to causes of death recorded at each death certificates. The rate that underlying causes of death for vital statistics were derived from underlying causes of death recorded at issued death certificaties sere analysed. Results : 64.5% of underlying cause of death for could be derived from underlying cause of death recorded at issued death certificates, 8.6% derived from intermediate cause of death, and 3.9% derived from direct cause of death. In 23% of cases, underlying cause of death could not be derived using issued death certificates. The rate that underlying cause of death for vital statistics could be derived from underlying cause of death recorded at death certificates was different between 3 university hospitals. Ane the rate was also different between death certificates and postmortem certificates. We classified the causes of death using 21 major categories. The rate was different between diseases or conditions tha caused death too. Conclusion : When we examined the correctness of death certificate writing practice using abpve methods, cortectness of writing could not be told as satisfactory. There was difference in correctness of writing between hospotals, between death certificates and postmortem certificates, and between diseases and conditions that caused death. With this results, we suggested some strategy to improve the correctness of death certificate writing practice.

      • KCI등재
      • Implementation Plans for the Korean Certified Tumor Registrar Qualification System

        Boo, Yoo-Kyung,Lim, Hyun-Sook,Won, Young-Joo Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.21

        Background: Cancer registration data is used to understand the nation's cancer burden, and to provide significant baseline data for cancer control efforts, as well as, research on cancer incidence, mortality, survival, and prevalence. A system that approves, assesses, and manages the qualification of specialists, responsible for performing cancer registration, has not been developed in Korea. This study presents ways to implement a certification system designed for the qualification of tumor registrars in Korea. Materials and Methods: Requirements for implementing a certified tumor registrar qualification system were determined by reviewing the system for establishing qualifications in Korea and the American qualification system via the National Cancer Registrars Association (NCRA). Moreover, a survey was conducted on Korean medical records administrators, who had taken the U.S. Certified Tumor Registrar (CTR) examination, in order to review their opinions regarding these requirements. Results: This study verified the feasibility of a qualification examination based on the opinions of CTR specialists by determining the following: items, and the associated ratings, of the qualifications necessary to register individuals as certified tumor registrars in a private qualification system; status of human resources required for the examination or training processes; plans regarding the organization needed for management, and operation of qualifications, examination standards, subject areas, examination methods, examination qualifications, or education and training programs. Conclusions: The implementation of a certified tumor registrar qualification system will lead to enhanced job competency for specialists and a qualitative improvement of cancer registration data. It will also reliably foster human resources that will lay the groundwork needed to establish scientific and reasonable national cancer management policies.

      • KCI등재

        체형지수와 체질량지수가 자살행동에 미치는 영향

        부유경(Yoo-Kyung Boo) 한국산학기술학회 2018 한국산학기술학회논문지 Vol.19 No.9

        본 연구의 목적은 자살에 영향을 미칠 수 있는 일반적 특성들과 동시에 체질량지수(Body Mass Index, BMI)를 통제함으로써 체형지수(A Body Shape Index, ABSI)가 자살생각과 자살시도와 어떠한 관련성이 있는지에 대해 알아보는 것이다. 2013년부터 2015년까지 질병관리본부의 제 6기 국민건강영양조사 자료를 이용하였으며, 자살행동에 영향을 미칠 수 있는 변수들에 대한 정보가 없는 자들을 대상에서 제외한 총 13,155명을 대상으로 카이제곱검정과 다변량 로지스틱회귀분석을 실시하였다. 분석 결과는 BMI에서 ‘비만’에 해당하는 자들이 BMI에서 ‘표준’에 해당하는 자들보다 자살생각과 자살시도가 높았고, ABSI에서는 Q3에 해당하는 그룹이 Q1에 해당하는 그룹에 비해 자살생각이 높았다. 자살시도는 ABSI에서 Q3에 해당하는 그룹이 Q1 그룹에 비해 3.623배(95% CI 1.027-12.772) 높았으며 유의한 결과를 보였다. 본 연구의 결과는 BMI와 비교하여 ABSI가 높이 나타나면 단순히 자살생각보다는 자살시도라는 더욱 극단적인 선택을 할 수 있음을 의미하는 것으로 우리 사회는 ABSI가 높은 자에 대해 사회적인 관심과 적절한 관리를 할 수 있도록 해야 할 것이다. The purpose of this study was to determine the association of the Body Shape Index (ABSI) with suicide ideation and suicide attempts by controlling the body mass index (BMI), as well as general characteristics that may affect suicide . The study has used The Sixth Korea National Health and Nutrition Examination Survey conducted by the Korea Centers for Disease Control and Prevention from 2013 to 2015. A total of 13,155 participants were studied, excluding those who had no information on variables that could affect suicidal ideations and suicidal attempts. The chi-squared test and the multivariate logistic regression analysis were performed. The results of the analysis showed that those who had obesity in BMI were more likely to commit suicide and suicide than those who were in ’standard’ in BMI. In ABSI, Q3 group was more likely to commit suicide than Q1 group . The number of suicide attempt was significantly higher in the group with Q3 in ABSI than in Q1 group (3.623 times (95% CI 1.027-12.772)). The results of this study suggest that a higher ABSI compared to BMI means that it is possible to make a more extreme choice of suicide attempt rather than suicide ideation.

      • KCI등재후보

        급성 심근경색증 환자에서 조기에 적절한 재관류 요법을 시행받지못한 요인

        유병수(Byung Su Yoo),윤정한(Jung Han Yoon),박금수(Keum Soo Park),여경구(Kyung Koo Yoh),조윤경(Yun Kyung Cho),안승찬(Seung Chan Ahn),이용규(Yong Kyu Lee),송광선(Kwang Seon Song),최경훈(Kyung Hoon Choe),이부수(Boo Soo Lee),황성오(Sung 대한내과학회 1995 대한내과학회지 Vol.48 No.6

        N/A Objectives: Early application of reperfusion therapy such as thrombolytic agent or direct PTCA is utmost important to amximize the efficacy of reperfusion therapy in patients with aute myocardial infarction. However, early adequate reperfusion thearpy was given only in 15% to 36% pf patients with acute myocardial infarction and substantial patients were not benefited from reperfusion therapy, Therefore, we performed these study to evaluate the reasons for which patients with acute myocardial infarction cannot receive an adequate reperfusion therapy. Methods: We analyzed the initial electrocardiogram and various time delays from chest pain onset time, first hospital arrival time, transfer time, ER arrival time, and door to reperfusion time in 138 patients with acute myocardial infarction from Jan. 1991 to Oct. 1993 admitted to Wonju Christian Hospital. Patients were grouped as reperfusion group(n=55) who had reperfusion therapy such as thrombolytic trial or direct PTCA and conservative grou who had not received reperfusion therapy(n= 83). Results: 1) Eighty-three cases(60.1%) did not received an adequate reperfusion therapy. 2) Hospital arrival time of patients was 237±162min and 786±615min in reperfusion and conservative group(p<0.05) respectively. Patient time delay was 103±98min and 439±511min, first hospital time delay, 93±78min and 333±482min, and transfer time, 81±59min and 105±64min in reperfusion and conservative group respectively(p<0.05). Only 4.8% of patients was transferred from first hospital after reperfusion therapy. 3) Patient time delay was the most common reason of not receiving reperfusion therapy, and time delay and lack of adequate reperfusion therapy at the first hospital inspite of early arrival were the second place. Other reasons were contraindication to lytic therapy(4 cases), definite Q wave MI(11 cases), inconclusive EKG(4 cases), and delay in therapy(4 cases). Conclusion: The most common reason of not receiving reperfusion therapy was patient delay in seeking medical care(45.8%) and time delay at first hospital in 22 cases(26.5%). To maximize the effectiveness of reperfusion therapy, it is important to shorten hospital arrival time delay and widespread use of reperfusion therapy at first hospital is recommeded.

      • KCI등재

        Evaluation of Sperm Sex-Sorting Method using Flow Cytometry in Hanwoo (Korean Native Cattle)

        Yoo, Han-Jun,Lee, Kyung-Jin,Lee, Yong-Seung,Lee, Chang-Woo,Park, Joung-Jun,Cheong, Hee-Tae,Yang, Boo-Keun,Park, Choon-Keun 韓國受精卵移植學會 2012 한국동물생명공학회지 Vol.27 No.1

        This study evaluated a method of sorting X and Y chromosomes based on size using the forward angle light scatter related refractive index (FSC) of a flow cytometer. Hanwoo bulls sperm were separated to X and Y chromosomes by the parameters of FSC or Hoechst 33342 intensity. As a result, using monitor program linked flow cytometry during sorting processing, the purities were or for the X-fraction and or for the Y-fraction in the two sperm sorting methods. There were no differences in the X and Y ratios (X and Y %) between the sperm sorting methods based on FSC or DNA content. The proportions of female and male embryos used for in vitro fertilization and development were or , and or when sperm were processed using the sex sorting method by FSC or Hoechst 33342. In conclusion, further study is needed to determine the optimum procedure and improve the nozzle to enhancing sorting accuracy or efficiency. Also, the findings of this study do not negate the possibility that the difference method of sperm sorting cannot use a UV laser beam.

      • KCI등재후보

        신장 ; Ezetimibe가 말기 신부전 환자의 혈중 지질 및 혈전 지표에 미치는 영향

        박경선 ( Kyung Sun Park ),여영선 ( Young Sun Yeo ),유미현 ( Mi Hyun Yoo ),최준석 ( Jun Seok Choi ),장지웅 ( Ji Woong Jang ),부선진 ( Sun Jin Boo ),유동준 ( Dong Jun Yoo ),김순배 ( Soon Bae Kim ) 대한내과학회 2009 대한내과학회지 Vol.77 No.4

        목적: 고지혈증은 말기 신부전 환자의 심혈관계 질환에 대한 주요한 위험인자 중 하나로, 고지혈증의 교정으로 심혈관계 질환의 빈도를 감소시킬 수 있다. 많은 수의 말기 신부전 환자들이 고지혈증에 대한 약물 치료를 시행함에도 혈중지질 이상이 적절하게 교정되지 않고 있다. 현재까지 주로 사용되었던 지질강하제와 다른 작용 기전을 갖는 새로운 약제인 ezetimibe는 정상 신장기능을 가진 일반인을 대상으로 한 기존 연구에서 우수한 지질 교정 효과와 내약성 및 안정성을 보였다. 이에 본원에서 혈액투석 및 복막투석을 시행 받고 있는 말기 신부전 환자들을 대상으로 ezetimibe 단독치료 시와 ezetimibe와 simvastatin을 병용하였을 때의 지질 강하 효과와 항 염증 효과 및 항 혈전 효과 등에 대해 알아보고자 하였다. 방법: 본원에서 3개월 이상 혈액투석 및 복막투석을 받고 있는 환자 중 저밀도 지단백 콜레스테롤 수치가 100 mg/dL 이상인 환자 65명을 대상으로 하였다. 이들을 ezetimibe 단독투여군과 ezetimibe/simvastatin 병용투여군으로 나누었다. ezetimibe 단독투여군에 속한 환자에게는 ezetimibe 10 mg을 하루 1회 복용하도록 하였고, ezetimibe/simvastatin 병용투여군에 속한 환자에게는 ezetimibe 10 mg과 simvastatin 10 mg의 혼합 제재를 하루 1회 복용하도록 하였다. 두 군 모두 8주간 약제를 복용하였다. 두 군의 환자 모두 연구 시작 시점과 종료 시점에 채혈을 하였다. 지질 지표로서 총 콜레스테롤, 저밀도 지단백 콜레스테롤, 고밀도 지단백 콜레스테롤 및 중성 지방 수치를 측정하였다. 염증 표지자로서 hs-CRP와 fibrinogen을 사용하였고, vWF는 내피세포 손상의 지표로 사용하였다. 혈관 내 혈전 생성의 지표로 D-dimer를 측정하였다. 결과: Ezetimibe 단독투여군과 ezetimibe/simvastatin 병용투여군 간에는 평균 연령, 성별, 투석 기간, 체질량지수에 차이가 없었다. 말기 신부전을 초래한 원인 질환에서도 두 군 간에 차이가 없었으며, 당뇨병, 고혈압, 심혈관계 질환, 간 질환, 갑상선 질환의 유병률에도 차이가 없었다. Calcium-channel blocker, β-blocker, angiotensin-converting enzyme inhibitor 및 angiotensin II receptor blocker의 사용 빈도도 두 군 간에 차이가 없었다. 혈중 지질수치의 기저치 및 hs-CRP, fibrinogen, vWF, D-dimer의 기저치에서도 두 군 간에 유의한 차이가 없었다. 약제사용 8주 후 ezetimibe 단독투여군에서 총 콜레스테롤 수치와 저밀도 지단백 콜레스테롤 수치는 각각 14.7%와 21.9% 감소하였다. 고밀도 지단백 콜레스테롤 수치와 중성 지방수치는 변화가 없었다. hs-CRP 감소하는 경향이었으나 통계적인 의미는 없었고, fibrinogen은 통계적으로 유의하게 증가하였다. vWF와 D-dimer는 증가하는 경향이었지만 통계적인 의미는 없었다. 약제사용 8주 후 ezetimibe/simvastatin 병용투여군에서 총 콜레스테롤 수치와 저밀도 지단백 콜레스테롤 수치는 각각 29.8%와 42.4% 감소하였다. 고밀도 지단백 콜레스테롤 수치와 중성 지방수치는 변화가 없었다. hs-CRP, fibrinogen, vWF, D-dimer는 감소하는 경향이었지만 통계적인 유의성은 없었다. 지질 지표와 hs-CRP, fibrinogen, D-dimer 수치의 변화 정도는 투석방법에 따라 차이가 없었지만 vWF는 ezetimibe 단독투여군과 ezetmibe/simvastatin 병용투여군 모두에서 복막투석 환자에서 유의하게 증가하였다. Ezetimibe 단독투여군과 ezetimibe/simvastatin 병용투여군 간에 부작용의 빈도 차이는 없었다. 결론: Ezetimibe는 말기 신부전 환자에게 단독사용 시에도 비교적 안전하게 혈중 지질 개선 효과를 보였으나, 내피세포 손상을 포함한 지혈 요소들이 증가하는 경향을 나타내었다. Statin과의 병용사용 시에는 단독사용 시와 비교하여 훨씬 더 우수한 혈중 지질 강하 효과를 나타내었고, 지혈 요소들도 증가하지 않았다. 따라서 ezetimibe는 단독으로 사용하였을 때보다 statin과의 병용 투여 시에 말기 신부전 환자의 혈중 지질이상을 교정하는 효과가 우수하며, 말기 신부전 환자에게도 안전하게 사용될 수 있는 약제라고 할 수 있다. Background/Aims: Dyslipidemia is one of the major causes of cardiovascular disease in end-stage renal disease (ESRD) patients. Most of them are dyslipidemic despite the use of lipid-lowering agents. Ezetimibe is a novel chemical entity that inhibits the intestinal absorption of dietary and biliary cholesterol. This study evaluated the effects of ezetimibe on the lipid profile, inflammation markers, endothelial injury, and thrombogenesis in ESRD patients. Methods: Sixty-five patients with serum low-density lipoprotein (LDL)-cholesterol levels≥100 mg/d were recruited: 33 patients were on hemodialysis and 32 patients were on peritoneal dialysis. They were assigned randomly to the ezetimibe (10 mg) monotherapy group and the ezetimibe (10 mg) plus simvastatin (10 mg) combination therapy group. Both drugs were administered for 8 weeks. Results: There were no significant differences in the baseline demographic and laboratory characteristics between the two groups. In the monotherapy group, the total and LDL-cholesterol levels were reduced by 14.7 and 21.9%, respectively. There were no changes in the high-density lipoprotein (HDL)-cholesterol or triglyceride levels. Fibrinogen increased significantly (p=0.04). In the combination therapy group, the total and LDL-cholesterol levels were reduced by 29.8 and 42.4%, respectively. There was an additional 15.1% reduction in total cholesterol and an additional 20.5% reduction in LDL cholesterol compared with monotherapy. Several patients complained of minor adverse effects and only one patient in the ezetimibe monotherapy group discontinued medication, because of diarrhea. Conclusions: In ESRD patients, ezetimibe used as combination therapy with a statin is more effective than ezetimibe monotherapy in ESRD patients. (Korean J Med 77:461-471, 2009)

      • SCOPUSKCI등재

        간장 및 담도 : 담도회충증의 임상 중상과 내시경적 치료 - 담낭염 및 췌장염 -

        김부성 ( Boo Sung Kim ),정진우 ( Jin Wu Jeong ),유혜신 ( Hye Sin Yu ),조상덕 ( Sang Deok Cho ),정성룡 ( Sung Ryung Chung ),유경진 ( Kyung Jin Yoo ) 대한소화기학회 1986 대한소화기학회지 Vol.18 No.1

        N/A Ascaris lumbricoides infection is usually asymptomatic, but when invasion of the ascaris to the human biliary tract is a prominent medical and surgical problems. Here we have two case reports of common bile duct ascariasis, which clinical manifestations were different each other, one is acute pancreatitis form and the other is acute cholangitis form. The management of biliary obstruction caused by ascaris lumbricoides has usually been surgical, but this report describes the endoscopic removal of the ascaris located in the common bile duct.

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