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      • 제주도 동부 연안역의 생물생태학적 기초연구(Ⅰ)-우도주변 연안역의 해수특성-

        최영찬,고유봉,이준백 濟州大學校 基礎科學硏究所 1994 基礎科學硏究 Vol.7 No.1

        제주도 동방 우도 연안역에서 60m수심까지 나타나는 몇가지의 물리, 화학적 성분의 분포양상과 특성에 대해 1991년 9월부터 1992년 7월까지 조사하였다. 성층현상이 일어나는 시기는 수심이 낮은 평균농도에서는 7월에, 수심이 깊은 우도외해에서는 7월부터 9월까지 지속되고 있었다. 용존산소의 평균농도는 8.10mg/l (6.04∼9.53mg/l) 로 년중 풍부한 상태였으며, 부유물질은 5.20 mg/l (0.85∼13.35mg/l) 로 표층에서가 30m, 60m층보다 다소 높게 나타났다. 부유물질에 대한 휘발성부유물질의 비는 동절기보다 하절기에 높은 비율이었다. 영양염류의 평균농도는 질산질소가 4.36㎍-at/l(0.17∼13.95㎍-at/l),인산인이 0.27㎍-at/l(0.01∼1.59㎍-at/l),규산규소가 5.39㎍-at/l(1.10∼12.97㎍-at/l)를 나타내고 있었다. 질산소와 인산인은 7월에 최저농도를 나타낸 반면 규산규소는 최대농도를 나타내고 있었다. N/P의 값은 모든해역, 전 수심에서 Redfield비인 16보다 약간 상회하는 값을 나타내고 있었으며, Si/P값이 전체적으로 낮게 나타나 본 해역에서는 외해수와 연안수와의 교환이 활발히 일어나고 있음을 시사해주고 있다. 엽록소-a 평균농도는 0.63mg/㎥ (0.10∼2.35mg/㎥ ) 였으며 7월과 9월에 대증식현상이 일어나고 있음을 보여주고 있었다. The distributions and characteristics of some physical and chemical properties shown down to the depth of 60m in the coastal waters near Udo, eastern part of Cheju Island, were investigated. Waters are stratified in July in shallow areas Udo Strait, and during July to September in deep areas open sea of Udo. The mean concentration value of dissolved oxygen is high as 8.10mg/l (6.04∼9.53mg/l) through the year, and that of suspended solids is 5.20 mg/l (0.85∼13.35mg/l) and a little higher in surface than in the depths of 30m and 60m. The ration of volatile suspended solids to suspended solids is higher in summer season than in winter season. The mean concentration values (the ranges in parentheses) of nitrate, phosphate, and silicate are 4.36㎍-at/l,(0.17∼13.95㎍at/l), 0.27㎍-at/l (0.01∼1.59㎍-at/l),and 5.39㎍-at/l (1.10∼12.97㎍-at/l), respectively. In July, the minimum concentration value of nitrate and the maximum concentration value of silicate are shown. The values of N/P is a little higher than Redfield ratio 16 in whole areas and depths and that of Si/P is generally low, which suggests that the coastal waters in survey area are well flushed by open sea waters. Chlorophyll-a has the mean concentration value of 0.63mg/㎥ (0.10∼2.35mg/㎥ ) and 2 great bloomings. one in May and the other in September.

      • KCI등재
      • KCI등재후보

        안면부에 발생한 고정형 스포로트리쿰증 3례

        최윤애,류영욱,정재봉,송준영,이규석 啓明大學校 醫科大學 1993 계명의대학술지 Vol.12 No.3

        We experienced 3 cases of fixed type cutaneous sporotrichosis confined to the face. Case 1 was a 32-month old child, affected over the nose. Case 2 was a 25-year old man, affected over the left cheek. Case 3 was a 71-year old man, affected over the nose. Histopathologically, chronic granulomatous inflammation with pseudoepitheliomatous hyperplasia was observed. Mycologically, typical dark brown to black colored colonines with moist, wrinkled and membranous surfaces were cultured. All patients were completely cured by oral administration of saturated KI and itraconazole combined therapy in a short period(40-90 days).

      • 담즙정체성 간염의 임상적 양상

        최선택,은종렬,임상우,김봉준,이헌주,구미진,최준혁 영남대학교 기초/임상의학연구소 2001 Yeungnam University Journal of Medicine Vol.18 No.1

        Background: Cholestatic hepatitis is failure of bile to reach the duodenum with hepatocellular damage and no demonstrable obstruction of the major bile ducts. The prognosis is usually good with recovery in less than 4 weeks after withdrawal of the offending drug. However, a prolonged course lasting over 3 months is possible and, in rare cases, progression to ductopenia with development of a vanishing bile duct syndrome occurs. A differential diagnosis with other causes of Chronic liver disease is needed. Materials and Methods: From January 1991 through Jaunary 2000, 14 patients diagnosed as cholestatic hepatitis by liver biopsy were inclouded. The possible causative drug, clinical features, laboatory findings, and progression of cholestatic hepatitis were evaluated. The semiquantitative study of liver lesions was performed by two independent observers. Results: Causes of cholestatic hepatitis are 5 cases of oriental medicine, 3 cases of anti-tuberculosis medication, 1 case of ticlopidine and antibiotics and 4 cases of unknown causes. The clinical features of cholestatic hepatitis were jaundice, itching, urine color change, and general weakness. During 6 to 30 months, LFT of 5 patients showed prolonged elevation. Elevated total cholesterol ≥250 mg/dL in 6 patients, pheripheral blood eosinophilia in 5 patients, auto-antibody positive in 6 patients were observed respectively. The biopsies showed intralobular bilirubinostasis with a mixed portal inflammatory infiltration. Conclusion: In cholestatic hepatitis. durations of abnormal LFT are variable regardless of causative drugs. If cholestatic hepatitis progresses toward chronic course, viral hepatitis, primary biliary cirrhosis, and autoimmune hepatitis should be differentially diagnosed and sequential liver biopsies are needed.

      • 제주도 동부 연안역의 생물생태학적 기초연구(ll) 우도주변 식물 플랑크톤 군집동태와 일차생산력

        이준백,좌종헌,고유봉,최영찬 濟州大學校 基礎科學硏究所 1994 基礎科學硏究 Vol.7 No.1

        제주도 동부연안역인 우도해역에서 1991년 9월부터 1992년 6월까지 격월로 식물플랑크톤 동태와 일차생산력의 수평적 및 수직적 정성, 정량자료를 분석하였다. 조사기간중 출현한 총 출현종수는 89종이며 규조류가 가장 많았고 그 외 와편모조류와 규질편모조류가 출현하였다. 이중 Chaetoceros diadema, C. socialis, Skeletonema costatum, Prorocentrum micans가 계절적 천이경향을 보이면서 우점하였다. 개체수의 월변화는 4,116∼588.68cells/l의 범위로써 11월에 최소치, 3월에 최대치를 보였다. 개체수의 수직분포는 수괴의 수직혼합 및 성층과 밀접한 관계를 보이고 있다. 수층의 평균 일일 일차생산력은 연안역 (정점1)에서 210.17(4.34∼588.68)mgC/m²/day, 외해역(정점7)에서 309.35(4.25∼804.55)mgC/m²/day를 나타내었다. 미세식물플랑크톤 (<20㎛)의 총 일차생산력에 대한 비율은 연안에서 37.6%와 외해에서 67.6%를 차지하며 외해역에서 더 높은 생산력을 보였다. 식물플랑크톤의 동화계수는 표층에서 0.17∼12.05mgC/mgChl-a/hr의 범위로써 춘계와 하계에서 높았다. 와편모조류중 Prorocentrum micans의 대발생은 하계의 저염현상과 밀접한 관계를 보였다. This study has been carried out to understand the dynamics and primary productivity of phytoplankton around U-do, eastern part of Cheju Island from September 1991 to June 1992. During the survey a total of 89 species were identified, comprising mainly diatom, and dinoflagellate and silicoflagellate as minority. Of these, Chaetoceros diadema, C. socialis, Skeletonema costatum, Prorocentrum micans predominated with seasonal succession. The cell number ranged from 4,116 to 812,748cell/l, showing the minimum in November and the maximum in March. The vertical distribution of cell number related closely with the vertical mixing and stratification of the water mass. The mean depth-integrated primary productivity was 210.17 (4.34∼588.68)mgC/㎡/day at st.1 (nearshore) and 309.36 (4.25∼804.55)mgC/㎡/day at st. 7 (offshore). The nanoplankton fraction (<20㎛)accounted for 37.4% and 67.6% of total primary productivity at st. 1 and st.7, respectively, representing higher productivities at offshore than at nearshore. Assimilation number by phytoplankton at the surface ranged from 0.17 to 12.05mgC/mgChl-a/hr, showing higher values in spring and summer. Dinoflagellate bloom of Prorocentrum micans may have a close relationship with the presence of lower salinity in summer.

      • 마우스 장내에서의 유산균과 이질균의 소장에 관한 연구

        李逢起,金周德,崔大卿,柳駿 최신의학사 1975 最新醫學 Vol.18 No.1

        The present study has been designed in order to clarify the multiplication and the effect of lactobacilli (shirota strain) on the growth of Shigella dysenteriae (type 1) in vitro and in vivo mouse cecum. The experimental results are summerized as follows. 1. The growth and multiplication of Shigella dysenteriae were inhibited when those organisms were inoculated on the L-broth medium culturedwith lactobacilli for 16 hours (pH 5-0). However, when Shigella dysenteriae was inoculated on the BHI broth medium already cultured with lactobacilli, -the growth and multiplication of those organism were observed, and pH of the medium was changed from 6.3 to 6.1 2. Whe both lactobacilli and Shigella dysenteriae were simultaneously inoculated on the L-broth or BHl broth medium, there were observed decreasing trends of survival of shigella organism, while lactobacilli gradualy grew and multiplied, and pH of the L-broth and BHI broth were changed from 6.8 to 5. 6 an d from 7. 2 to 6.3 respectively. 3. There was no distinct growth and multiplication of lactobacilli in mouse cecum by oral administration, although there was a slight fluctuation in the number of lactobacilli organisms. 4. Shigella organisms was detected with gradual decreasing numbers untill the fourth day after inoculation by mouth. However the survial of Shigella organisms in mouse cecum was rapidly decreased and disappeared within one day by the oral administration of lactobacilli solution. Based on the above experimental results it is deduced that lactobacilli are generally unable to be multiplicated in mouse cecum and to affect pH change of mouse cecum, and that shigella dysenteriae survival in mouse cecum seems not to be affected by pH fluctuation.

      • 제주도 서부 연안역의 생물생태학적 기초연구(Ⅰ) : 고산주변 연안역의 해수특성 Sea Water Properties of Coastal Zone around Gosan

        고유봉,최영찬,이준백 濟州大學校海洋硏究所 1994 해양과환경연구소 연구논문집 Vol.18 No.-

        The distributions and characteristics of some physical and chemical properties shown down to the depth of 60m in the coastal water near Gosan in the western part of Cheju Island have been investigated during May 1992 to March 1993. Waters are not stratified in shallow inner-part, but stratified in mid-part and outer-part from June up to later than September. The mean concentration of dissolved oxygen is high though the year, and was 130% over-saturated on the depth of 60m in March. The concentration of suspended solids shows its maximum value on the depth of 60m in February, which is thought to be due to the resuspension of bottom muds. Most nutrients show their maximum values in February and their minimum values in June. Specially, in June when nitrate, phosphate, silicate etc. show their minimum values, the concentration of chlorophyll-a shows its maximum value. N/P is a little lower than 16, which is Redfield ratio, in the layer from surface to the depth of 30m and in the inner-part up to the mid-part, but similar in the layer deeper than the depth of 60m and in the outer-part. Si/P is generally lower, which indicates vivid circulations between waters in the outer and inner-part and on the surface and bottom layers. The mean concentration value of chlorophyll-a is 0.49㎎/㎥(0.10-1.23㎎/㎥) and shows great bloomings in June.

      • KCI등재

        저열량영양식품 섭취에 따른 비만여성의 체중감량 효과에 관한 연구

        박순영,최중명,김동현,최경식,최봉근,윤태영,유동준 한국보건통계학회 2002 보건정보통계학회지 Vol.27 No.1

        In the method of obesity treatment, Dietary method, Exercise method, Behavior method, and Drug method, Dietary method is the most important control method of obesity. The aim of this study is that evaluate the weight reduction effect of the specific low calorie diet products (KSD I and 2) in obese women. Twenty five women who were volunteer participated in this study. They have no heart diseases and metabolic diseases. we classified two groups : obese group and standard group. Anthropometric indices were measured in all subject for four times. Venous blood sample were taken to determine the lipid profiles, glucose level, and liver function test. In obese group, body weight were reduced 2.85±1.46kg, but showed statistically non-signicicant. Body mass index were gradually reduced, 1.09±0.93kg/m^2(p<0.05).In blood analyses, total cholesterol were reduced 10.61 ±33.4mg/dℓ ( p<0.05). KSD 2 significantly inhibited maltase, sucrase and α-glucosidase from rat intestine, and porcine pancreatic lipase, although KSD I inhibited only the sucrase.

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