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Anand Sharma,Nitesh K. Chourasia,Vishwas Acharya,Nila Pal,Sajal Biring,Shun-Wei Liu,Bhola N. Pal 대한금속·재료학회 2020 ELECTRONIC MATERIALS LETTERS Vol.16 No.1
Low surface-roughness and high-capacitance ion-conducting LiAlO2 gate dielectric thin flm has been fabricated by sol–gel technique to develop ultra-low voltage (≤1.0 V) indium-zinc-oxide thin flm transistor (TFT). This LiAlO2 dielectric shows α-LiAlO2 and γ-LiAlO2 phases those have been fabricated at two diferent temperatures. For both phases, mobile Li-ion is responsible to achieve a high dielectric constant (κ) of the material that helps to reduce the operating voltage of TFT. Additionally, lower surface roughness of LiAlO2 thin flm creates a low-density trap state in the semiconductor/dielectric interface which is capable to reduce operating voltage within 1.0-volt. The device with 700 °C annealed γ-LiAlO2 gate dielectric shows the best device performance with an electron mobility of 25 cm2 V−1 s−1 and an on/of ratio of 3×105 . Instead, 350 °C annealed α-LiAlO2 dielectric require only one volt to saturate the drain current and shows its mobility and on/of ratio are 13.5 cm2 V−1 s−1 and 1×104 respectively. Such kind of unusually low operation voltage TFT fabrication becomes possible because of the higher Li+ mobility of α-LiAlO2 gate dielectric and very low surface trap density. A model on carrier transport mechanism has been prepossessed to explain this achievement.
Radioprotective and Antioxidant Activity of Fractionated Extracts of Berries of Hippophae rhamnoides
Rakesh Kumar Sharma,Raman Chawla,Rajesh Arora,Shikha Singh,Ravinder Kumar Sagar,Raj Kumar,Ashok Sharma,Manju L. Gupta,Surender Singh,Jagdish Prasad,Haider A. Khan,Anand Swaroop,A.K. Sinha,A.K. Gupta,R 한국식품영양과학회 2007 Journal of medicinal food Vol.10 No.1
Plants are an abundant source of medicinal compounds, some of which are useful in combating free radical-1002 (flavonoid-poor fraction) of Hippophae rhamnoideswere screened on the basis of their reducing power in the aqueousphase. REC-1001 was selected for further study, since it exhibited 27.38 times higher antioxidant activity than REC-1002.REC-1001 also showed significant (P. .05) membrane protection potential at 50 .g/mL, which was attributed to its abilityto scavenge peroxyl radicals (64.82. 1.25% scavenging within 1,440 min). A significant (P. .05) difference of 67.02% infree radical scavenging activity at 1,000 ng/mL between REC-1001 and vitamin E demonstrated the extract fraction’s worthc-tion. Further, REC-1001 was found to be nontoxic up to 200 mg/kg of body weight. This research suggests that the REC-1001 fraction of H. rhamnoidesextract is a safe and effective antioxidant nutraceutical product.
Anand Kumar,Dinesh K. Sharma,Rajeev Lochan,Saurabh Dewan,Suman Negi 국립중앙과학관 2020 Journal of Asia-Pacific Biodiversity Vol.13 No.2
Asian black francolin (Francolinus francolinus asiae) is an important bird species in the northwestern Himalayanregion, inhabiting diverse subtropical to lower temperate habitat types. The relative abundance,habitat preference, and some aspects of breeding ecology are studied here at eleven sites in different habitattypes along elevation gradient. The abundance of species at different altitude was worked both throughtransect trails of different lengths and point counts at some spots. At each study site, maximum activityhabitats were marked and selected for breeding ecology study. Sighting of black francolin was minimal inApril (0.585 0.185 birds/Km) and maximum in May (2.339 0.015 birds/Km). Data on breeding timings,nest site selection, clutch size, incubation period, and hatching success were collected. Breeding period ofblack francolin extended from March up to late July with peak egg-laying between May to June. Twelvenests were monitored throughout the breeding season using binoculars from a distance and camera traps,wherever possible and without disturbing the species. The average size of nest was 20.063 1.452 cmranging from of 18.80 cm to 22.30 cm in width. Mean clutch size was 5.417 0.793 eggs/nest. The hatchingsuccess was 86.15% with 56 successfully hatched eggs, whereas the fledging success was 83.92%.
CHAOTIC RESPONSE ANALYSIS OF SINGLE-WALLED CARBON NANOTUBE DUE TO SURFACE DEVIATIONS
ANAND Y. JOSHI,SATISH C. SHARMA,S. P. HARSHA 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2012 NANO Vol.7 No.2
Nonlinear vibrational behavior of a single-walled carbon nanotube based mass sensors is considered. The modeling involves stretching of the mid plane and damping. The equation of motion involves two nonlinear terms due to the curved geometry and the stretching of the central plane due to the bridged boundary conditions. The manifestation of instability and chaos in the dynamic response is observed. The regions of periodic, sub-harmonic and chaotic behavior are clearly seen to be dependent on added mass and the surface deviations. Poincaré maps and frequency spectra are used to explicate and demonstrate the miscellany of the system behavior.
Ajay Sharma,Anand Nagar,Peeyush Varshney,Maunil Tomar,Shashwat Sarin,Rajendra Prasad Choubey,V. K. Kapoor 한국간담췌외과학회 2022 Annals of hepato-biliary-pancreatic surgery Vol.26 No.2
Backgrounds/Aims: Pancreaticoduodenectomy is the most common procedure for the management of duodenal pathologies. However, it is associated with substantial morbidity and a low risk of mortality. Pancreas-preserving limited duodenal resection (PPLDR) can be performed under specific scenarios. We share our experience with PPLDR and its outcome. Methods: We retrospectively analyzed a prospectively maintained database of patients undergoing limited duodenal resection in the form of wedge (sleeve) resection or segmental resection of one or more duodenal segments from March 2016 to March 2021 at a tertiary care center in North India. Results: During the study period, 10 patients (including 9 males) underwent PPLDR. Five of these 10 patients showed primary duodenal or proximal jejunal pathology, while the remaining five had duodenal pathology involving an adjacent organ tumor. Four patients underwent wedge (sleeve) resection, while the remaining six underwent segmental duodenal resection of one or more duodenal segments. Mean hospital stay was 6 days (range, 3–11 days) without 30-day mortality. Morbidity occurred in 4 patients (Grade I–II, n = 3; Grade III, n = 1). All patients were alive and disease-free at the time of last follow-up. The mean follow-up duration was 23 months (range, 2–48 months). Conclusions: PPLDR is a safe and effective alternative for pancreaticoduodenectomy when selected carefully for specific tumor types and location.
Kour Savleen,Sharma Neelesh,Guttula Praveen Kumar,Gupta Mukesh Kumar,Santos Marcos Veiga dos,Bacic Goran,Macesic Nino,Pathak Anand Kumar,손영옥 아세아·태평양축산학회 2024 Animal Bioscience Vol.37 No.3
Objective: Transition period is considered from 3 weeks prepartum to 3 weeks postpartum, characterized with dramatic events (endocrine, metabolic, and physiological) leading to occurrence of production diseases (negative energy balance/ketosis, milk fever etc). The objectives of our study were to analyze the periodic concentration of serum beta-hydroxy butyric acid (BHBA), glucose and oxidative markers along with identification, and validation of the putative markers of negative energy balance in buffaloes using in-silico and quantitative real time-polymerase chain reaction (qRT-PCR) assay. Methods: Out of 20 potential markers of ketosis identified by in-silico analysis, two were selected and analyzed by qRT-PCR technique (upregulated; acetyl serotonin o-methyl transferase like and down regulated; guanylate cyclase activator 1B). Additional two sets of genes (carnitine palmotyl transferase A; upregulated and Insulin growth factor; downregulated) that have a role of hepatic fatty acid oxidation to maintain energy demands via gluconeogenesis were also validated. Extracted cDNA (complementary deoxyribonucleic acid) from the blood of the buffaloes were used for validation of selected genes via qRTPCR. Concentrations of BHBA, glucose and oxidative stress markers were identified with their respective optimized protocols. Results: The analysis of qRT-PCR gave similar trends as shown by in-silico analysis throughout the transition period. Significant changes (p<0.05) in the levels of BHBA, glucose and oxidative stress markers throughout this period were observed. This study provides validation from in-silico and qRT-PCR assays for potential markers to be used for earliest diagnosis of negative energy balance in buffaloes. Conclusion: Apart from conventional diagnostic methods, this study improves the understanding of putative biomarkers at the molecular level which helps to unfold their role in normal immune function, fat synthesis/metabolism and oxidative stress pathways. Therefore, provides an opportunity to discover more accurate and sensitive diagnostic aids.
Manoj Kumar Sharma,Sumeet Kainth,Sachin Kumar,Ankit Bhardwaj,Hemant Kumar Agarwal,Rakhi Maiwall,Kapil Dev Jamwal,Saggere Muralikrishna Shasthry,Ankur Jindal,Ashok Choudhary,Lovkesh Anand,Rajender Mal 대한간학회 2019 Clinical and Molecular Hepatology(대한간학회지) Vol.25 No.2
Background/Aims: The aim of this study was to study the efficacy and safety of zolpidem for sleep disturbances in patients with cirrhosis. Methods: Fifty-two Child-Turcotte-Pugh (CTP) class A or B cirrhotics with Pittsburgh Sleep Quality Index >5 were randomized to either zolpidem 5 mg daily (n=26) or placebo (n=26) for 4 weeks. Results: The therapy of 4 weeks was completed by 23 patients receiving zolpidem (3 stopped treatment due to excessive daytime drowsiness) and 24 receiving placebo (2 refused to continue the study). In the zolpidem group, after 4 weeks of therapy, there was significant increase in total sleep time (TST) and sleep efficiency compared to baseline and improvement in polysomnographic parameters of sleep initiation and maintenance (i.e., decrease in sleep latency time, decrease in wake time, and decreases in number of arousals and periodic limbs movements per hour of sleep), without any significant change in sleep architecture. Conclusions: Four weeks of 5 mg daily zolpidem in CTP class A or B cirrhosis patients with insomnia led to significant increases in TST and sleep efficiency and improvement in polysomnographic parameters of sleep initiation and maintenance without any significant change in sleep architecture.