Performance Study of Various Routing Protocols in VANET Case of Study

Mohamed Ben Ahmed,A. A. Boudhir,M. Bouhorma,K. Ben Ahmed 보안공학연구지원센터 2014 International Journal of Future Generation Communi Vol.7 No.6

Vehicular ad hoc networks or VANET that establishes wireless connections between cars have recently received considerable attention. VANET are used in Intelligent Transportation Systems (ITS) that are designed to offer passengers and vehicles services like warning of accidents, driver assistance, Internet access, etc. The evaluation of VANET routing protocols often involves simulators since management and operation of a large number of real vehicular nodes is expensive. We study the behavior of routing protocols in VANETs by using mobility information obtained from a microscopic vehicular traffic simulator that is based on the real road maps of Tangier in Morocco. In this paper, we evaluate AODV, DSR and OLSR performance in urban scenarios case study. We study those protocols under varying metrics such as node mobility, vehicle density, and with varying traffic rates. We show that clustering effects created by cars aggregating at intersections have remarkable impacts on evaluation and performance metrics. Our objective is to provide a qualitative assessment of the applicability of the protocols in different vehicular scenarios. The results show that OLSR performs best in most of the simulated traffic situations

Camellia sinesis leaves extract ameliorates high fat diet-induced nonalcoholic steatohepatitis in rats: analysis of potential mechanisms

Mohamed Safaa H.,Shahat Abdelaaty A.,Mohamed Mohamed Ragaa,Khalil Wagdy K. B.,Salem Ahmed M.,Farrag Abdel Razik H.,Ahmed Hanaa Hamdy 한국약제학회 2021 Journal of Pharmaceutical Investigation Vol.51 No.2

Purpose Our research aims to address and determine the effect of Camellia sinensis extract in the management of nonalcoholic steatohepatitis (NASH) in rats. Methods Forty adult female albino rats were divided into four groups. Group 1 (G1) served as the control group, while the other three groups received high-fat diet for 32 weeks to induce NASH and then were later assigned to the following groups: (G2) NASH-afflicted group which was left untreated, (G3) NASH-afflicted group treated with Camellia sinensis extract in a dose of 400 mg/kg, and (G4) NASH-afflicted group treated with Camellia sinensis extract in a dose of 200 mg/kg. Results Significant elevation in serum alanine aminotransferase, albumin, bilirubin (total and direct), cholesterol, low density lipoprotein, triglycerides, leptin, Cox-2, and CD40 values was recorded. Moreover, overexpression of hepatic tumor necrosis factor alpha and hepatocyte growth factor genes were recorded, whereas blood platelet count and serum high density lipoprotein concentration revealed significant depletion, which was paralleled by significant downregulation of hepatic adiponectin gene expression level in NASH group versus the control group. On the opposite side, treatment of NASH groups with two different doses of Camellia sinensis extract reversed the values of the measured biochemical parameters and the targeted gene expression levels when compared with the NASH group. Optical micrograph of liver tissue sections of rats treated with Camellia sinensis extract showed the observed improvement in the studied biochemical and genetic markers. Conclusion This study provides a clear evidence for the promising therapeutic potential of Camellia sinensis extract against NASH. This could be ascribed to its hepatoprotective activity, hypolipidemic effect, and anti-inflammatory potency.

Physical characterization and radiation shielding features of B2O3-As2O3 glass ceramic

Mohamed Y. Hanfi,Ahmed K. Sakr,A.M. Ismail,Bahig M. Atia,Mohammed S. Alqahtani,K.A. Mahmoud 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.1

The synthetic B2O3eAs2O3 glass ceramic are prepared to investigate the physical properties and the radiation shielding capabilities with the variation of concentration of the As2O3 with 10, 20, 30, and 40%, respectively. XRD analyses are performed on the fabricated glasseceramic and depicted the improvement of crystallinity by adding As2O3. The radiation shielding properties are studied for the B2O3eAs2O3 glass ceramic. The values of linear attenuation coefficient (LAC) are varied with the variation of incident photon gamma energy (23.1e103 keV). The LAC values enhanced from 12.19 cm1e37.75 cm1 by raising the As2O3 concentration from 10 to 40 mol% at low gamma energy (23.1 keV) for BAs10 and BAs40, respectively. Among the shielding parameters, the halfevalue layer, transmission factor, and radiation protection efficiency are estimated. Furthermore, the fabricated samples of glass ceramic have low manufacturing costs and good shielding features compared to the previous work. It can be concluded the B2O3eAs2O3 glass ceramic is appropriate to apply in X-ray or low-energy gamma-ray shielding applications.

The effect of alpha-lipoic acid supplementation on anthropometric, glycemic, lipid, oxidative stress, and hormonal parameters in individuals with polycystic ovary syndrome: a systematic review and meta-analysis of randomized clinical trials

Ahmed Abu-Zaid,Saeed Baradwan,Ibtihal Abdulaziz Bukhari,Abdullah Alyousef,Mohammed Abuzaid,Saleh A. K. Saleh,Heba M. Adly,Osama Alomar,Ismail Abdulrahman Al-Badawi 대한산부인과학회 2024 Obstetrics & Gynecology Science Vol.67 No.1

This systematic review and meta-analysis aimed to examine the effect of the antioxidant alpha-lipoic acid (ALA) on various cardiometabolic risk factors and hormonal parameters in patients with polycystic ovary syndrome (PCOS). We searched PubMed, EMBASE, SCOPUS, Cochrane Library, and Web of Science databases without language restrictions until May 2023 to find randomized controlled trials (RCTs) that assessed the impact of ALA supplementation on anthropometric, glycemic, lipid, oxidative stress, and hormonal parameters in women with PCOS. Outcomes were summarized using the standardized mean difference (SMD) and 95% confidence interval (CI) in a random-effects model. An I2 statistic of >60% established significant between-study heterogeneity. The overall certainty of the evidence for each outcome was determined using the grading of recommendations, assessment, development, and evaluations system. Seven RCTs met the inclusion criteria. The ALA group had significant reductions in fasting blood sugar (fasting blood sugar (FBS), n=7 RCTs, SMD, -0.60; 95% CI, -1.10 to -0.10; I2=63.54%, moderate certainty of evidence) and homeostatic model assessment for insulin resistance (homeostatic model assessment of insulin resistance (HOMA-IR), n=4 RCTs, SMD, -2.03; 95% CI, -3.85 to -0.20; I2=96.32%, low certainty of evidence) compared with the control group. However, significant differences were observed between the groups in body mass index, insulin, estrogen, follicle-stimulating hormone, luteinizing hormone, testosterone, low-density lipoprotein, highdensity lipoprotein, triglyceride, total cholesterol, malondialdehyde, or total antioxidant capacity profiles. ALA supplementation improves FBS and HOMA-IR levels in women with PCOS. ALA consumption is an effective complementary therapy for the management of women with PCOS.

Dexmedetomidine during suprazygomatic maxillary nerve block for pediatric cleft palate repair, randomized double-blind controlled study

Mohamed F. Mostafa,Fatma A. Abdel Aal,Ibrahim Hassan Ali,Ahmed K. Ibrahim,Ragaa Herdan 대한통증학회 2020 The Korean Journal of Pain Vol.33 No.1

Background: For children with cleft palates, surgeries at a young age are necessary to reduce feeding or phonation difficulties and reduce complications, especially respiratory tract infections and frequent sinusitis. We hypothesized that dexmedetomidine might prolong the postoperative analgesic duration when added to bupivacaine during nerve blocks. Methods: Eighty patients of 1-5 years old were arbitrarily assigned to two equal groups (forty patients each) to receive bilateral suprazygomatic maxillary nerve blocks. Group A received bilateral 0.2 mL/kg bupivacaine (0.125%; maximum volume 4 mL/side). Group B received bilateral 0.2 mL/kg bupivacaine (0.125%) + 0.5 µg/kg dexmedetomidine (maximum volume 4 mL/side). Results: The modified children’s hospital of Eastern Ontario pain scale score was significantly lower in group B children after 8 hours of follow-up postoperatively (P < 0.001). Mean values of heart rate and blood pressure were significantly different between the groups, with lower mean values in group B (P < 0.001). Median time to the first analgesic demand in group A children was 10 hours (range 8-12 hr), and no patients needed analgesia in group B. The sedation score assessment was higher in children given dexmedetomidine (P = 0.03) during the first postoperative 30 minutes. Better parent satisfaction scores (5-point Likert scale) were recorded in group B and without serious adverse effects. Conclusions: Addition of dexmedetomidine 0.5 μg/kg to bupivacaine 0.125% has accentuated the analgesic efficacy of bilateral suprazygomatic maxillary nerve block in children undergoing primary cleft palate repair with less postoperative supplemental analgesia or untoward effects.

Existence, Uniqueness and HU-Stability Results for Nonlinear Fuzzy Fractional Volterra-Fredholm Integro-Differential Equations

Ahmed A. Hamoud,Nedal M. Mohammed,Homan Emadifar,Faraidum K. Hamasalh,Soubhagya Kumar Sahoo,Masoumeh Khademi,Foroud Parvaneh 한국지능시스템학회 2022 INTERNATIONAL JOURNAL of FUZZY LOGIC and INTELLIGE Vol.22 No.4

In this paper, we established some new results concerning the existence and uniquenessof the solutions of nonlinear Atangana-Baleanu-Caputo fractional (ABC-fractional) FuzzyVolterra-Fredholm integro-differential equations. These new findings are obtained using thetheorems of a fixed point. In addition, we investigate Hyers-Ulam stability for this fractionalsystem. Our work extends and improves the results in the literature. Finally, some examplesdemonstrate the validity of the obtained theoretical results.

The impact of omeprazole on mycophenolate pharmacokinetics in kidney transplant recipients

( Mohamed S. Abdelhalim ),( Ahmed S. Kenawy ),( Heba H. El Demellawy ),( Amany A. Azouz ),( Sarah S. Alghanem ),( Torki Al-otaibi ),( Osama Gheith ),( Mohamed Abd Elmonem ),( Mohammed K. Afifi ),( Rag 대한신장학회 2020 Kidney Research and Clinical Practice Vol.39 No.4

Background: The absorption rates of mycophenolate mofetil (MMF) and enteric-coated mycophenolate sodium (ECMPS) may be influenced by the concomitant use of omeprazole. Methods: One hundred kidney transplant patients were recruited during their outpatient visits, including 50 on MMF and 50 on EC-MPS. At the clinic, a predose mycophenolic acid (MPA) sample (C0) was collected; subsequently, the participants received the proton-pump inhibitor omeprazole along with either MMF or EC-MPS. Two more blood samples were collected at 1.5 and 3.5 hours and used to estimate an area under the curve (AUC) from zero to 12 hours [AUC (0-12)]. Results: The mean number of months after transplant was 92 months. The median AUC (0-12) and C0 results were 62.2 mg·h/L and 2.0 mg/L for the MMF group and 71.9 mg·h/L and 1.8 mg/L for the EC-MPS group (P = 0.160 and 0.225, respectively). Interestingly, 54% of the MMF group and 62% of the EC-MPS group showed AUCs above the target values. The correlation between MPA C0 and the predicted AUC was poor in both groups. Conclusion: Omeprazole can be safely co-administered with either MMF or EC-MPS, as it did not compromise the MPA exposure. Unexpectedly, however, a high percentage of patients presented MPA AUCs exceeding the target value, highlighting the importance of periodically assessing MPA level.

Optimal Economic and Environmental Indices for Hybrid PV/ Wind-Based Battery Storage System

Elnozahy Ahmed,Yousef Ali M.,Ghoneim Sherif S. M.,Abdelwahab Saad A. Mohamed,Mohamed Moayed,Abo-Elyousr Farag K. 대한전기학회 2021 Journal of Electrical Engineering & Technology Vol.16 No.6

This paper shows an application of hybrid PV/wind energy and battery storage in the islanded area. This work’s main target allows the distributed energy resources to contribute effi ciently in the economic feasibility and enhance the environmental impact of the hybrid renewable energy source. Several factors such as levelized cost of energy (COE), greenhouse gas (GHG) emissions, and loss of power supply probability are studied. A combined solution is to compromise the economic and environmental aspects via the Utopia point approach is investigated. The optimal confi guration of the hybrid PV/wind along with battery-storage and diesel engine as secondary source is obtained via meta-heuristic optimizers: Genetic Algorithm (GA) and Particle-Swarm Optimization (PSO) and impartial comparison of the results with HOMER software. The results of Utopia point solution show that the PV (about 46%) and wind turbine (about 13%) are shared signifi cantly as primary renewable sources and battery storage (about 39%) as storage options. Meanwhile, the diesel engine (about 3%) has insignifi cant sharing in feeding the demand load. The optimal COE and GHG, which are achieved via GA and PSO optimization techniques are 0.182$/kWh and 12076 kg/year, agansit 0.343$/kWh and 17618 kg/year that are obtained via HOMER software, respectively. This corssponing to 47% and 31% reduction in COE and GHG, respectively. Sensitivity studies demonstrate that the variation of the wind energy sharing from 50 to 150% shows that the wind energy has a slight eff ect considering the GHG emissions. Contrarily, lower PV sharing ratios undesirably raises the levelized COE, however, reduces the GHG emissions.

Computational Studies on the Reaction from Silyl 1,4-Dilithio 1,3-butadiene to Lithio Silole

김창곤,Ahmed A. K. Mohammed,Eugene Wee,손창국,김찬경 대한화학회 2016 Bulletin of the Korean Chemical Society Vol.37 No.1

The reaction mechanisms forming lithio silole, 2, from silyl 1,4-dilithio 1,3-butadiene, 1, were examined theoretically at the CCSD/6-31+G(d)//B3LYP/6-31+G(d) level of theory in the gas phase. To account for the solvent effects, the reactions in diethyl ether were examined using the polarizable continuum model of the integral equation formalism (IEFPCM) with the united atom topological (UA0) cavity model at the IEFPCM-CCSD/6-31+G(d)//IEFPCM-B3LYP/6-31+G(d) level of theory. Without hexamethyl-phosphoramide (HMPA) as a cosolvent, the lithio silole, 2, was not produced due to the higher activation barrier, which is comparable to the homolytic cleavage of CC and/or CS bonds. On the other hand, the reaction could be feasible if HMPA solvates strongly or dissociates two Li+ cations from the reaction system. This suggests that HMPA plays a decisive role in the reaction. The optimized structures of the stationary point species on the potential energy surfaces in diethyl ether were similar to those in the gas phase, suggesting that the solvent effects on the structures of stationary species were not so large. On the other hand, theΔ E ZPVE ≠ values in diethyl ether showed larger changes from the corresponding values in the gas phase.

MicroRNAs and Metastasis-related Gene Expression in Egyptian Breast Cancer Patients

Hafez, Mohamed M.,Hassan, Zeinab K.,Zekri, Abdel Rahman N.,Gaber, Ayman A.,Rejaie, Salem S. Al,Sayed-Ahmed, Mohamed M.,Shabanah, Othman Al Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.2

Aim and background: MicroRNAs (miRNAs) are a class of naturally occurring small noncoding RNAs that regulate gene expression, cell growth, differentiation and apoptosis by targeting mRNAs for translational repression or cleavage. The present study was conducted to study miRNAs in Egyptian breast cancer (BC) and their relation to metastasis, tumor invasion and apoptosis in addition to their association with the ER and PR statuses. Methods: Real Time RT-PCR was performed to identify the miRNA expression level of eight miRNAs and eight metastatic-related genes in 40 breast cancer samples and their adjacent non-neoplastic tissues. The expression levels of each miRNA relative to U6 RNA were determined using the $^{2-{\Delta}}CT$ method. Also, miRNA expression profiles of the BC and their corresponding ANT were evaluated. Results: The BC patients showed an up-regulation in miRNAs (mir-155, mir-10, mir-21 and mir-373) with an upregulation in MMP2, MMp9 and VEGF genes. We found down regulation in mir-17p, mir-126, mir-335, mir-30b and also TIMP3, TMP1 and PDCD4 genes in the cancer tissue compared to the adjacent non-neoplastic tissues. Mir -10b, mir -21, mir-155 and mir373 and the metastatic genes MMP2, MMP9 and VEGF were significantly associated with an increase in tumor size (P < 0.05). No significant difference was observed between any of the studied miRNAs regarding lymph node metastasis. Mir-21 was significantly over-expressed in ER-/PR-cases. Conclusion: Specific miRNAs (mir-10, mir-21, mir-155, mir-373, mir-30b, mir-126, mir-17p, mir-335) are associated with tumor metastasis and other clinical characteristics for BC, facilitating identification of individuals who are at risk.