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      • 혈장 삼투질 농도 변동에 따른 항이뇨 호르몬과 Aldosterone 분비조절 : 한국청년

        이원정,주영은,구자훈,Lee, Won-Jung,Choo, Young-Eun,Koo, Ja-Hoon 대한생리학회 1987 대한생리학회지 Vol.21 No.2

        A study was carried out to find out the relationship between arginine vasopressin (AVP) release and plasma osmolality in 15 young men (age: 21.4 yr). After an overnight fasting, wale. (20 ml/kg) was imbibed, and venous blood and urine samples were collected every 30 min for 90 min. then 5% saline was infused (0.06 ml/min/kg) for 120 min. AVP was extracted on Sep-Pak column and measured by radioimmunoassay. Under basal condition, plasma osmolality (pOsm), AVP (pAVP) and aldosterone (pAldo) levels were 286.5 mOsm/kg, 1.1 pg/ml, and 140 pg/ml, respectively. pAVP became undetectable during maximum water diuresis, and increased in response to hypertonic saline infusion. pAVP level began to increase when pOsm was above 280 mOsm/kg. Changes in urinary AVP excretion (uAVP) was parallel to pAVP levels. The fall in pAVP was followed by a decrease in uAVP, uOsm and an increase in free water clearance, while the later rise in pAVP was followed by an increase in uAVP, uOsm and a decrease in free water clearance. When pooling all data together, relationships between pAVP and pOsm, and uAVP and uOsm were best expressed by an exponential relationship (r=0.78, 0.86, respectively). pAldo level decreased to 71 pg/ml after water ingestion, and decreased further to 30 pg/ml 2 hr after 5% saline infusion. Even at the same pNa, pAldo level during dehydration state was significantly higher than during hydration state. Negative exponential relation (r=-0.59) was observed between pAldo and pNa. Response to change in body fluid volume was greater in aldosterone than in AVP release.

      • KCI등재

        부산지역 미세먼지에 대한 건강 취약성 평가

        이원정,황미경,김유근,Lee, Won-Jung,Hwang, Mi-Kyoung,Kim, Yoo-Keun 한국환경보건학회 2014 한국환경보건학회지 Vol.40 No.5

        Objectives: This study seeks to evaluate the vulnerability assessment of the human health sector for $PM_{10}$, which is reflected in the regional characteristics and related disease mortality rates for $PM_{10}$ in Busan over the period of 2006-2010. Methods: According to the vulnerability concept suggested by the Intergovernmental Panel on Climate Change (IPCC), vulnerability to $PM_{10}$ is comprised of the categories of exposure, sensitivity, and adaptive capacity. The indexes of the exposure and sensitivity categories indicate positive effects, while the adaptive capacity index indicates a negative effect on vulnerability to $PM_{10}$. Variables of each category were standardized by the rescaling method, and each regional relative vulnerability was computed through the vulnerability index calculation formula. Results: The regions with a high exposure index are Jung-Gu (transportation region) and Saha-Gu (industrial region). Major factors determining the exposure index are the $PM_{10}$ concentration, days of $PM_{10}{\geq}50$, ${\mu}g/m^3$, and $PM_{10}$ emissions. The regions that show a high sensitivity index are urban and rural regions; these commonly have a high mortality rate for related disease and vulnerable populations. The regions that have a high adaptive capacity index are Jung-Gu, Gangseo-Gu, and Busanjin-Gu, all of which have a high level of economic/welfare/health care factors. The high-vulnerability synthesis of the exposure, sensitivity, and adaptive capacity indexes show that Dong-Gu and Seo-Gu have a risk for $PM_{10}$ potential effects and a low adaptive capacity. Conclusions: This study presents the vulnerability index to $PM_{10}$ through a relative comparison using quantitative evaluation to draw regional priorities. Therefore, it provides basic data to reflect environmental health influences in favor of an adaptive policy limiting damage to human health caused by vulnerability to $PM_{10}$.

      • KCI등재

        환경보건적 요소가 도시 내 폭염 취약성 평가 결과에 미치는 영향 분석

        이원정,강재은,김유근,Lee, Won-Jung,Kang, Jae-Eun,Kim, Yoo-Keun 한국환경보건학회 2013 한국환경보건학회지 Vol.39 No.6

        Objectives: This analysis seeks to evaluate the impact of environmental health factors (EHF; e.g. hospital beds per capita, employees of medical institutions) on extreme-heat vulnerability assessment in Busan Metropolitan City during 2006-2010. Methods: According to the vulnerability concept suggested by the Intergovernmental Panel on Climate Change (IPCC), extreme-heat vulnerability is comprised of the categories of Exposure, Sensitivity, and Adaptive Capacity (including EHF). The indexes of the Exposure and Sensitivity categories indicate positive effects, while the Adaptive capacity index indicates a negative effect on extreme-heat vulnerability. Variables of each category were standardized by the re-scaling method, and then each regional relative vulnerability was computed with the vulnerability index calculation formula. Results: The extreme-heat vulnerability index (EVI) excepting EHF was much higher in urban areas than in suburban areas within the metropolitan area. When EHF was considered, the difference in the EVI between the two areas was reduced due to the increase of the Adaptive capacity index in urban areas. The low EVI in suburban areas was induced by a dominant effect of natural environmental factors (e.g. green area) within the Adaptive capacity category. Conclusions: To reduce the vulnerability to extreme heat in urban areas, which were more frequently exposed to extreme heat than others areas, public health and natural environments need to be improved in sensitive areas.

      • 소금과 고혈압

        이원정(Lee Won-Jung) 동아시아식생활학회 1999 동아시아식생활학회 학술발표대회논문집 Vol.- No.-

        A reduced NaCl intake for the general population of the world has been recommended to reduce the overall blood pressure level and hence to reduce the overall incidence of cardiovascular disease. A high NaCl diet convincingly contributes to elevated arterial pressure in humans and animal models of hypertension. Among individuals there is considerable variability of blood pressure responsiveness to NaCl intake. In normotensive as well as hypertensive subjects, blood pressure can be judged to be salt sensitivity (SS) when observed to vary directly and substantially with the net intake of NaCl. The prevalence of SS in normotensive adults in the U. S. ranges from 15% to 42% 1md in hypertensive adults from 28% to 74%. SS is a risk factor for hypertension and may be an important marker in the identification of children for hypertension prevention programs. High NaCl intakes produce expansion of the extracellular fluid volume and thus increase blood pressure. Nonchloride salts of sodium does not expand the extracellular fluid volume and does not alter blood pressure. Blood pressure response to NaCl may be modified by other components of the diet. Low dietary intakes of potassium or calcium augment NaCl-induced increases of blood pressure. Conversely, high dietary intakes, of potassium or calcium attenuate NaCl-induced hypertension. A greater intakes of potassium or calcium may prevent or delay the occurrence of hypertension. SS occurs when dietary potassium is even marginally deficient but is dose-dependently suppressed when dietary potassium is increased within its normal range. Orally administered KHCO₃, abundant in fruits and vegetales, but not KCl has a calcium-retaining effect which may contributed to its reversal of pressor effect of dietary NaCl. Since nutrients other than NaCl also affect blood pressure levels, a reduced NaCl intake should be only one component of a nutritional strategy to lower blood pressure.

      • KCI등재
      • KCI등재
      • KCI등재

        X선에 노출된 보리의 생장과 엽록소 측정

        이원정(Won-Jeong Lee),이모권(Mo-Kwon Lee),이중록(Lee Jung Rok),김하늘(Kim Ha Neul),유세종(Se-Jong Yoo),이배원(Bae-Won Lee),정순철(Sun-Cheol Jeong) 대한방사선과학회(구 대한방사선기술학회) 2021 방사선기술과학 Vol.44 No.3

        The purpose of this study is to measure of growth and chlorophyl in barley exposed by X-ray. Barley seed was soaked 24h duration in water, then was classified into two group; pre-seed germination group (Pre-G) or post-seed germination group (Post-G). Also, divided as control subgroup and experimental subgroup(10Gy, 20Gy, 30Gy) in each group. Experimental subgroups were exposed by X-ray using linear accelerator (Clinac IS, VERIAN, USA). Expose condition was 6 MV X-ray, SSD 100 cm, 18×10 cm, 600 MU/min. Length was measured every day for 10 days and 10th day for weight. Chlorophyl was analyzed using spectrophotometer(uv-1800, shimadzu, japan) in l0th day. Data analysis was performed using SPSS ver 22.0(Chicago, IL, USA), ANOVA test (Dunnett_T3) between control subgroup and experimental subgroup in group and Independent T-test between Pre-G and Post-G in subgroup. In Pre-G, length of barley was significantly difference between control and 30Gy in 4th day (4.3 vs. 1.5, p= 0.011). Length of 30Gy was statistical difference with control(10th day; 14.4 vs. 6.3, p < 0.01), and was not in 10Gy or 20Gy in all day. In experimental subgroup, length was shorter as increasing radiation dose. In Post-G, length of barley was not difference statistically between control and experimental subgroup in first day, but more difference between two subgroup with increasing duration after exposing. Length of experimental subgroup was shorter significantly compared with control in 10th day, and no significant difference between experimental subgroup. Density of chlorophyl was increasing with increasing radiation dose in Pre-G and Post-G. Chlorophyl density of control was lower than 30Gy; 0.26ppm in Pre-G, 0.29ppm in Post-G). Growth and chlorophyl of barley was effected by X-ray. It is expected to be used as basic data for future radiobiological research.

      • KCI등재
      • KCI등재후보

        중국 애니메이션 교육 현황과 기업체 산학협력 실태조사

        이원정(Lee Won-Jung) 한국만화애니메이션학회 2009 만화애니메이션연구 Vol.- No.17

        최근 중국의 애니메이션산업은 정부와 사회 전체의 주목을 받으며 빠르게 발전하고 있다. 각 지역마다 거대 규모의 애니메이션 시장에 대응하기 위해서 분주하게 애니메이션 산업 활성화 방안을 모색하고 있고, 기존의 OEM생산방식에서 탈피하여 자체 역량을 발휘하여 창작 능력이 극대화된 수많은 애니메이션을 제작하고 있다. 중국의 애니메이션 관련산업의 매출규모가 우리의 10배를 넘는 현재에 이르기까지 중국 애니메이션 산업 발전의 근간이 되는 애니메이션 교육현황과 그 교육을 통한 산학협력방식에 대한 구체적인 연구가 부족한 편이다. 이에 본 논문은 중국 현지 6개 애니메이션 관련 대학을 직접 방문하여 애니메이션 교육현황을 조사, 분석하였고, 중국 내 주요 애니메이션 관련기업 10여개 업체를 직접 방문하여 중국 내 애니메이션 관련 산업현장에서의 산학협력실태를 조사하였다. 이 조사를 통하여 중국내 산학협력방식의 실태와 문제점을 파악할 수 있었고 이러한 분석을 토대로 우리나라의 대학 및 산업체에서 수행할 수 있는 산학협력체제의 여러 방안을 제언하고자 한다. 이 연구를 통하여 기존에 미흡했던 중국 내 산학협력체계에 대한 집중적인 연구의 시금석을 제공할 수 있고, 오늘날 우리나라 교육 현실에 접목한 많은 선행연구로서의 활용가치가 있다고 사료된다. Recently, the animation industry in China is rapidly developing drawing the government and the whole society's attention. To cope with a large-scale animation market by each region, they busily seek revitalization program of animation industry and are producing lots of animations that maximized their creative ability with its own competence and breaking the existing OEM production method. Up to now, when the scale of sales related with animation in China exceeds 10 times than that in Korea, the concrete studies on current state of animation education AS the basis of development of animation industry of China and the way of academic-industrial cooperation through that education are proved to be insufficient. Therefore, this study has surveyed and analyzed the current state of animation education by directly visiting 6 local universities related with animation. Equivocally, it has also examined current state of academic-industrial cooperation in industrial field related with animation in China by directly visiting around 10 main companies related with animation in China. Through this study, it has been possible to grasp the current state and problems of academic-industrial cooperation in China and various programs of academic-industrial cooperation system that can be implemented in universities and businesses which are intended to be suggested to them as based on this analysis. The touchstone of intensive studies on academic-industrial cooperation system in China could be suggested through this study, which has been previously unsatisfactory and it is considered to be worthy of application as many preceding studies that engraft on reality of education in the country today.

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