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TRIP 형 복합조직강판의 기계적 성질에 미치는 2 단 열처리 영향
이영섭,김용성,윤종구,박현순 ( Y . S . Lee,Y . S . Kim,J . K . Yoon,H . S . Park ) 한국열처리공학회 1998 열처리공학회지 Vol.11 No.3
Heat treatment conditions and the formation of microstructures were studied for improving the transformation-induced plasticity(TRIP) effect of retained austenite and mechanical properties of Fe-0.2%C-1.5%Si-1.5%Mn sheet steel. An excellent combination of elongation about 30% and high strength over 760 ㎫ was achieved by processing of intercritical annealing and isothermal holding. Intercritical annealing the sheet steel produced fine particles(1∼2㎛) of retained austenite which were stabilized due to C enrichment by subsequent holding in bainite transformation range. Heat treatment conditions were depended on the shape and distribution of second phases as well as the volume fraction and stability of retained austenrte. In this work, the heat treatment condition of optimal strength-elongation balance was obtained by holding the steel at 400℃ for 200sec. after intercritical annealing at 790℃ for 300sec.
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모의실험에 의한 온실가스 인벤토리 불확도 산정을 위한 지수분포 신뢰구간 추정방법
이영섭,김희경,손덕규,이종식,Lee, Yung-Seop,Kim, Hee-Kyung,Son, Duck Kyu,Lee, Jong-Sik 한국데이터정보과학회 2013 한국데이터정보과학회지 Vol.24 No.4
An estimation of confidence intervals is essential to calculate uncertainty for greenhouse gases inventory. It is generally assumed that the population has a normal distribution for the confidence interval of parameters. However, in case data distribution is asymmetric, like nonnormal distribution or positively skewness distribution, the traditional estimation method of confidence intervals is not adequate. This study compares two estimation methods of confidence interval; parametric and non-parametric method for exponential distribution as an asymmetric distribution. In simulation study, coverage probability, confidence interval length, and relative bias for the evaluation of the computed confidence intervals. As a result, the chi-square method and the standardized t-bootstrap method are better methods in parametric methods and non-parametric methods respectively.
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망막정맥폐쇄 환자에서 유리체내 베바시주맙 주입술의 2년 임상 결과
이영섭,김무상,유승영,곽형우,Young Seob Lee,Moo Sang Kim,Seung Young Yu,Hyung Woo Kwak 대한안과학회 2011 대한안과학회지 Vol.52 No.9
Purpose: The authors evaluated the 2-year clinical results of intravitreal bevacizumab injection in retinal vein occlusion (RVO). Methods: Thirty-two eyes of 32 patients treated with an intravitreal bevacizumab injection of 1.25 mg (0.05 ml) for RVO (branch RVO: 22 eyes, central RVO: 10 eyes), repeated 3 times at a 6-week interval and were available for a follow-up period of at least 2 years were retrospectively reviewed. Best-corrected visual acuity (BCVA) before treatment and 6, 12, and 24 months after 3 serial injections, was recorded. The optical coherence tomography (OCT) results were analyzed to identify prognostic factors for recurrent macular edema that needed reinjection. Results: Two years after the treatment, mean BCVA was significantly improved (<em>p</em> = 0.000). Out of 32 eyes, 16 (branch RVO: 8 eyes; central RVO: 8 eyes) needed reinjection because of recurrent macular edema. In central RVO, a significantly high reinjection rate was shown in serous retinal detachment (SRD) compared with cystoid macular edema (CME) as identified in OCT findings (<em>p</em> = 0.049). Additionally, in branch RVO, a high reinjection rate was shown in SRD, although statistically not significant (<em>p</em> = 0.375). Conclusions: In patients with RVO, a significant visual improvement was maintained for at least 2 years after intravitreal bevacizumab injection. Based on OCT results, SRD showed a high reinjection rate compared with CME in CRVO. J Korean Ophthalmol Soc 2011;52(9):1039-1047
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이영섭,강계월,최원규,Lee, Young-Sub,Kang, Kae-Wool,Choi, Won-Kyu 대한소아소화기영양학회 2001 Pediatric gastroenterology, hepatology & nutrition Vol.4 No.2
Purpose: Ingested foreign bodies present a common clinical problem. It is well known that most of them pass uninterrupted through the gastrointestinal tract. We evaluated the role of endoscopy and Foley catheter for removal of foreign bodies in the gastrointestinal tract. Methods: We investigated retrospectively 60 cases with foreign bodies in the gastrointestinal tract. They had been treated at Wonju Christian Hospital, Yonsei University of Korea, from January, 1996 through December, 1999. Results: The age of the patients ranged from 7 months to 13 years. Patients under 5 years were 57 cases (97%) and there was no significant difference in sex (M : F=1.07 : 1). 45 cases of the patients had no symptom. The most common foreign bodies were coins (43 cases). The most common location was esophagus (31 cases). The number of foreign body removal using flexible endoscopy and Foley catheter was 22 (36.7%) and 18 (30.0%) cases, respectively. In 18 cases (30.0%), foreign bodies passed spontaneously. Only 1 case (1.7%), curtain pin impaction at ileocecal region, required surgery. Conclusion: Early foreign body removal from esophagus and stomach is recommended to lessen the morbidity and complication. Fluoroscopic foley catheter technique and flexible endoscopy for removal of esophageal foreign bodies in children is safe and effective.
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The Role of Gap Junction in the Goldfish's Motion Detection Measured with Optometer Response
이영섭,윤영현,정창섭,Lee, Young-Sub,Yoon, Young-Hyun,Jung, Chang-Sub Korean Society of Medical Physics 2006 의학물리 Vol.17 No.4
갭 정션(gap junction)은 다양한 세포에 분포되어 있으며 분자 수준의 작은 물질들이 자유롭게 교환되는 전기적 시냅스다. 망막에서, 갭 정션의 차단이 동물의 동작 감지(motion detection)에 실제적으로 어떤 영향을 주는지에 대해서는 거의 조사되지 않았다. 본 연구에서는, 망막 세포간의 전기적 시냅스를 조절하는 약물이 금붕어의 동작 감지에 어떠한 영향을 주는지를 조사하기 위해 시각운동 반응(optometer response, OMR)이 사용되었다. 갭 정션 차단제인 carbenoxolone, 8-bromo cyclic AMP, sodium nitroprusside (SNP), 8-bromo-cyclic GMP 등의 초자체 내 주사는 광- 및 암-상태에서 모두 OMR을 감소시켰다. 광-상태에서 dopamine, SKF-38393 및 eticlopride의 주사는 OMR을 감소시킨 반면 SCH-23390의 주사는 OMR을 증가시켰다. 암-상태에서는 결과가 반대로 나타났다: 즉 dopamine, SKF-38393 및 eticlopride의 주사는 OMR을 증가시킨 반면 SCH-23390의 주사는 OMR을 감소시켰다. 이러한 결과는 망막 세포들 사이의 갭 정션이 금붕어의 동작 감지에 중요한 역할을 담당하고 있음을 시사한다.
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이영섭,박성식,박은경,Lee, Yong-Seop,Park, Seong-Sik,Park, Eun-Kyung 사상체질의학회 2001 사상체질의학회지 Vol.13 No.2
By the increasing concern about Sasang Constitution Medicine, its practical use is considered very important in disease prevention and medical treatment. However, the method of constitution classification is depending on the doctor's clinical trials because of the lack of the objective test criteria. This study is trying to improve the objectiveness of diagnosis using a new statistical method, decision tree. Decision tree method-a classification technique in the statistical analysis- was used to analyze the result of QSCCII instead of using discriminant analysis. As a result, 16 among 121 QSCCII questions was selected as important questions and 21 terminal nodes was built to classify the constitution. Using only 16 questions shown in the result of decision tree, we can diagnose and interpret the constitution easily and effectively.
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