http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
홍 우석,윤영훈 조선대학교 IT연구소 2022 정보기술융합공학논문지 Vol.12 No.1
본 연구에서는 정량주입펌프와 멀티 방사노즐로 구성된 전기방사 시스템을 활용하여 100㎚ 반경의 나노섬유를 제조하였다. 고분자 나노섬유 제조 과정에서 인가전압과 토출량의 변화가 나노섬유의 미세구조에 미치는 영향을 조사하였다. 전기방사 과정에서 인가전압이 높아지고 토출량이 낮아질 때 국부영역에서 나노섬유의 뭉침 현상이 나타났다. 이는 전기방사 시 전하밀도, 표면장력, 점탄성 등 공정변수를 제어할 때 상호작용으로 비딩 현상이 일어나고 알갱이가 달린 나노섬유가 형성되는 것으로 나타났다. 본 연구에서는 이러한 문제점을 해결하기 위해서 인가전압과 토출량의 변수를 조절하여 미세구조 관찰 및 분진포집효율을 측정하였다. 전기방사 과정에서 인가전압과 토출량은 15~25kV와 0.3, 0.6, 0.9ml/h의 조건으로 방출하였으며, 나노섬유의 표면 형상과 분포상태, 분진 포집 효율을 분석하였다.
우석원(Seok-Won Woo),전덕인(Duk-In Jon),홍현주(Hyun Ju Hong),정명훈(Myung Hun Jung),홍나래(Narei Hong) 대한사회정신의학회 2021 사회정신의학 Vol.26 No.2
연구목적 : 코로나바이러스 감염증(COVID-19) 진단을 받지 않은 자가격리 의무자는 코로나바이러스 감염증 진단을 받은 환자와 유사한 수준의 사회적 고립, 외로움, 불안, 우울증 및 두려움에 노출된다. 점점 늘어나는 자가격리자의 수에 비해 이들에 대한 정신건강에 대한 평가가 제한된 상태였다. 본 연구는 코로나바이러스 감염증에 대한 자가격리 의무자 중 정신 건강 문제가 있는 개인의 특성을 확인하고자 하였다. 방 법 : 2020년 2월부터 2020년 8월까지 한국의 일개 시에서 코로나바이러스 감염증에 대한 자가격리요청을 받은 3,400명을 대상으로 Clinical Global Impression Severity (CGI-S) 점수를 통하여 정신 건강 문제를 평가하였다. CGI-S 2점 이상을 유증상 군, CGI-S 1점을 무증상 군으로 나눠서 두 그룹 사이의 사회인구학적 요인의 차이를 chi-square 및 Mann-Whitney 검정을 사용하여 분석하 였다. 결 과 : 코로나바이러스 감염증으로 자가격리 요청을 받은 3,400명의 대상자 중 3,001명을 인터뷰하였고 대상자의 49.2%(n=1,477)가 여성 이었으며 평균 연령은 39.86세였다. 유증상 군은 무증상 군에 비해 평균연령(p<0.0001)이 유의하게 높았고 여성(p=0.001)과 내국인(p=0.001)의 비율도 높았다. 내국인은 외국인보다 정신건강문제와 연관성이 4.73배(confidence interval [CI], 1.74-12.89, p=0.001) 있는 것으로 나타났고, 여성은 남성보다 정신건강문제 관련 연관성이 1.83배(CI, 1.28-2.63, p=0.001) 있는 것으로 나타났다. 결 론 : 유증상 군은 무증상 군에 비해 고령인구와 내국인, 여성의 비율이 더 높았다. 따라서 향후 의무적 자가격리 기간 동안 자가격리자들 중 고령자, 내국인 및 여성을 대상으로 정신건강 서비스의 초점을 맞춰야 할 것으로 생각된다. Objectives : Individuals in mandatory self-quarantine not diagnosed with Coronavirus disease 2019 (COVID-19) are subject to a similar level of social isolation, loneliness, anxiety, depression, and fear as that experienced by patients diagnosed with COVID-19. Our aim was to identify the specific characteristics of individuals with mental health problems under a self-quarantine order for COVID-19. Methods : We contacted 3,400 individuals requested to undergo self-quarantine for COVID-19 by the government from February 2020 to August 2020 in one city in Korea. The Clinical Global Impression Severity (CGI-S) score was used to assess mental health problems. Differences in sociodemographic factors between symptomatic (CGI-S≥2) and asymptomatic (CGI-S=1) individuals were analyzed using chi-square and Mann-Whitney tests. Results : Of 3,400 subjects, 3,001 who were requested to self-quarantine for COVID-19 were interviewed; 49.2% (n=1,477) of subjects were female, and the mean age was 39.86 years. The symptomatic group had a significantly higher mean age (p<0.0001) and higher proportions of females (p=0.001) and Korean nationals (p=0.001) than the asymptomatic group. Korean nationals were 4.73 times (confidence interval [CI]=1.74-12.89, p=0.001) more likely to have mental health problems than non-Korean nationals and females were 1.83 times (CI=1.28-2.63, p=0.001) more likely to have mental health problems than males Conclusion : The symptomatic group consisted of an older population and a higher proportion of Korean nationals and females than the asymptomatic group. We must focus on individuals with nationality of the same country, females, and those of older age for mental health services during mandatory self-quarantine.
태우석,주은연,김성태,홍승봉 대한영상의학회 2010 Korean Journal of Radiology Vol.11 No.1
Objective: To identify changes in gray and white matter concentrations (GMC, WMC), and their relation to heterotopic neuron numbers in mesial temporal lobe epilepsy (mTLE). Materials and Methods: The gray matter or white matter concentrations of 16 left and 15 right mTLE patients who achieved an excellent surgical outcome were compared with those of 24 healthy volunteers for the left group and with 23 healthy volunteers for the right group, by optimized voxel-based morphometry using unmodulated and modulated images. A histologic count of heterotopic neurons was obtained in the white matter of the anterior temporal lobe originating from the patients’ surgical specimens. In addition, the number of heterotopic neurons were tested to determine if there was a correlation with the GMC or WMC. Results: The GMCs of the left and right mTLE groups were reduced in the ipsilateral hippocampi, bilateral thalami, precentral gyri, and in the cerebellum. The WMCs were reduced in the ipsilateral white matter of the anterior temporal lobe, bilateral parahippocampal gyri, and internal capsules, but increased in the pons and bilateral precentral gyri. The heterotopic neuron counts in the left mTLE group showed a positive correlation (r = 0.819, p < 0.0001) with GMCs and a negative correlation (r = - 0.839, p < 0.0001) with WMCs in the white matter of the anterior temporal lobe. Conclusion: The present study shows the abnormalities of the cortico-thalamo-hippocampal network including a gray matter volume reduction in the anterior frontal lobes and an abnormality of brain tissue concentration in the pontine area. Furthermore, heterotopic neuron numbers were significantly correlated with GMC or WMC in the left white matter of anterior temporal lobe. Objective: To identify changes in gray and white matter concentrations (GMC, WMC), and their relation to heterotopic neuron numbers in mesial temporal lobe epilepsy (mTLE). Materials and Methods: The gray matter or white matter concentrations of 16 left and 15 right mTLE patients who achieved an excellent surgical outcome were compared with those of 24 healthy volunteers for the left group and with 23 healthy volunteers for the right group, by optimized voxel-based morphometry using unmodulated and modulated images. A histologic count of heterotopic neurons was obtained in the white matter of the anterior temporal lobe originating from the patients’ surgical specimens. In addition, the number of heterotopic neurons were tested to determine if there was a correlation with the GMC or WMC. Results: The GMCs of the left and right mTLE groups were reduced in the ipsilateral hippocampi, bilateral thalami, precentral gyri, and in the cerebellum. The WMCs were reduced in the ipsilateral white matter of the anterior temporal lobe, bilateral parahippocampal gyri, and internal capsules, but increased in the pons and bilateral precentral gyri. The heterotopic neuron counts in the left mTLE group showed a positive correlation (r = 0.819, p < 0.0001) with GMCs and a negative correlation (r = - 0.839, p < 0.0001) with WMCs in the white matter of the anterior temporal lobe. Conclusion: The present study shows the abnormalities of the cortico-thalamo-hippocampal network including a gray matter volume reduction in the anterior frontal lobes and an abnormality of brain tissue concentration in the pontine area. Furthermore, heterotopic neuron numbers were significantly correlated with GMC or WMC in the left white matter of anterior temporal lobe.