초음파로 진단된 지방간의 유병율 조사 및 그 유발인자에 대한 연구

안재억,함정오,황규윤,김주자,이병국,남택승,김정순,김헌,Ahn, Jae-Eog,Ham, Jung-Oh,Hwang, Kyu-Yoon,Kim, Joo-Ja,Lee, Byung-Kook,Nam, Tack-Sung,Kim, Joung-Soon,Kim, Hun 대한예방의학회 1991 예방의학회지 Vol.24 No.2

Fatty liver is caused by derangement of fat metabolism and can be reversed by removal of contributing factors. The contributing factors of fatty liver is known to be overweight, chronic alcoholism, diabetes mellitus, malnutrition, and drug abuse such as tetracycline. This study was carried out on 1335 persons who visited 'Soon Chun Hyang Human Dock Center' from March to June 1990. In analysis of the data, prevalence of fatty liver diagnosed by ultrasonogram by age and sex, laboratory finding between fatty liver group and normal group, and odds ratio of known contributing factors, were compared. The results obtained are as following ; 1) The prevalence rate of fatty liver diagnosed by ultrasonogram is 29.6% in male and 11.5% in female. 2) Age groups with high prevalences are $40{\sim}50's$ in male (32.0%) and 50's in female (24.5%). 3) The fatty liver shows significant association with style (p<0.05), whereas not with hepatitis B-virus surface antigen (p>0.05). 4) All laboratory values except alkaline phosphatase and bilirubin are elevated significantly in accordance with the degree of fatty liver (p<0.01). 5) Fatty liver diagnosed by ultrasonogram showed so strong associations with body index, triglycerides and gamma-glutamyl transferase for males, and body index and fasting blood sugar for females that these factors may be used as supplementary data in establishing diagnosis of fatty liver. 6) Odds ratio of contributing factors are as follows ; If the odds ratio of below 29 year of age is 1.0 then that of $30{\sim}39$ is 1.74 (p=0.33), $40{\sim}49$ is 2.47 (p=0.10), $50{\sim}59$ is 2.86 (p=0.0570), over 60 is 1.81 (p=0.34). If the odds ratio of female is 1.0 then that of male is 5.67 (p<0.01). If the odds ratio of body index below zero is 1.0 then that of $0{\sim}9$ is 5.08 (p<0.01), $10{\sim}19$ is 12.37 (p<0.01), $20{\sim}29$ is 29.19 (p<0.01), 30 above is 154.02 (p<0.01). If the odds ratio of below 99 mg/dl FBS is 1.0 then that of $100{\sim}120$ is 106 (p=0.76), over 120 is 1.91 (p=0.02). If the odds ratio of below $29{\mu}/1{\gamma}-GT$ is 1.0 then that of $30{\sim}s59$ is 2.11 (p<0.01), $60{\sim}90$ is 1.87 (p<0.05), 90 above is 1.69 (p=0.15). If the odds ratio of below 149 mg/dl TG is 1.0 then $150{\sim}199$ is 1.49 (p=0.05), $200{\sim}250$ is 1.09 (P=0.77), 250 above is 2.53 (p<0.01). In summary, early diagnosis of fatty liver could be made by ultrasonogram supplemented with body index and nm triglyceride. The fatty liver could be preventive by avoiding contributing factors such as obesity, alcohol intake, high blood sugar appropriately.

연 축전지 사업장의 질환 요주의자 및 유소견자의 사후관리 실태 연구

리갑수,황보영,김용배,김화성,함정오,이성수,안규동,이병국,허정,Lee, Gap-Soo,HwangBo, Young,Kim, Yong-Bae,Kim, Hwa-Sung,Ham, Jung-Oh,Lee, Sung-Soo,Ahn, Kyu-Dong,Lee, Byung-Kook,Hur, Jung 대한예방의학회 1996 예방의학회지 Vol.29 No.4

연 업종별 보건관리 대행기관에 의해 근로자의 보건 관리를 하고 있는 5개 연 축전지 회사의 전체 근로자들 중 1995년에 일반 건강진단 및 특수 건강진단을 동시에 시행한 전체 1,919명의 근로자 중에서 C(건강관리 상 계속 관찰이 필요한자)와 D(유소견자)의 판정을 받은 365명의 근로자들을 대상으로 하여 이들 중 퇴직자 35명, 조사 기간중 출장, 휴직 및 야간 근무자 8명, 그리고 조사에 응하지 않은 근로자 29명 등 총 72명을 제외한 293명을 대상으로 설문 및 1995년도 일반 및 특수 건강진단 결과표를 통하여 건강진단 결과에 따른 사후관리 조치실태 및 관련 요인들을 조사하였다. 결과를 요약하면 다음과 같다. 1. 요주의자 이상근로자의 86%가 건강진단결과표를 받았으나 이에 대한 교육설명이 제대로 이루어지지 않았고, 자신의 건강진단 결과를 잘 알고 있지 못하였다. 2. 사후관리 조치가 있었던 근로자는 23%로 낮았으며, 사후관리조치의 내용은 단순한 추적관찰이 가장 많았다. 3. 조사대상 근로자들은 현재의 건강진단은 필요하지만 형식적이라고 하였다. 4.사후관리 조치의 유무를 피설명변수로 한 로지스틱 회귀분석에서 유의한 설명 변수는 건강진단 결과에 대한 설명의 유무뿐이었다. To evaluate the follow-up management state and related factor of lead battery workers in periodic health examination as part of program of group occupational health service, author studied 293 workers with questionnaire on knowledge of results and follow-up management state and related factors, and compared the responses to their periodic health examination result charts. The results were as follows: 1. 252(86%) workers responsed that they had received the health examination result chart, but only 116(39.6%) workers responsed that they had been educated or explained about the results of health examination, and 11(57.9%) workers among 19 workers with non-occupational disease D, 101(44.3%) workers among 228 workers with non-occupational disease C, and 19(28.4%) workers among 67 workers with occupational disease C knew accurately their health examination results. 2. 78(24.8%) of the workers responsed that they had follow-up management, and contents of follow-up management were follow-up(36.6%), out-patient treatment (31%), change worksite(8.5%), temporary retirement(7.0%) and others(16.9%). 3. Most of the workers responsed that the health examination were necessary, but three-fourths of the workers responsed that the health examination had been superficial or that they didn't know. 4. In this study, follow-up management show significant association with only explanation or education about health examination result chart.

제 4기 국민건강영양조사 자료를 이용한 근로자들의 근로형태,작업환경 및 유해요인 노출과 건강검진결과의 관련성

김성훈 ( Sung Hun Kim ),김남수 ( Nam Soo Kim ),이창곡 ( Chang Gok Lee ),함정오 ( Jung Oh Ham ),이병국 ( Byung Kook Lee ) 한국산업위생학회 2013 한국산업보건학회지 Vol.23 No.3

Objectives: This study was designed to investigate the current status of the association of job-related information such as employment status, workplace environment, and hazard material exposures with health examination outcomes. Methods: The study used data from KNHANES 2007-2009 representing the three years of 2007-2009, which was conducted annually using a rolling sampling design that involved a complex, stratified, multistage, probability-cluster survey of a representative sample of the non-institutionalized civilian population in Korea. The final analytical sample consisted of 17,240 participants. Information on age, education, smoking history and alcohol intake was collected during the health interview. Job related information consisted of employment status, workplace environment, and hazardous material exposure. The selected indices of health examination were blood pressure, fasting glucose, blood cholesterol, HDL, SGOT, SGPT, and BUN. Results: In multiple logistic regression analysis using hypertension and pre-hypertension as dependent variables and job related categories as independent variables after covariate adjustments, the odds of hypertension and pre-hypertension were significantly lower in those with responsibility and power in their job activities. Interestingly, low odds for hypertension were observed among those who reported that their jobs were fast-paced. Conclusions: This study confirmed that some job-related categories in employment status, workplace environment, and hazardous material exposure had an association with health outcome status. It is worthwhile to comment that high responsibility and power in job activities were revealed as one of the important favorable factors to improve health condition of workers.

일부 석면광산 인근주민의 사회심리적 스트레스에 관한 연구

신영식(Young-Sik Shin),이용진(Yong-Jin Lee),함정오(Jung-Oh Ham),장은철(Eun-Chul Jang),박찬호(Chan-Ho Park),강민성(Min-Sung Kang),박승권(Seung-Kwon Park) 대한직업환경의학회 2012 대한직업환경의학회지 Vol.24 No.4

작업환경측정이 작업환경개선에 미치는 효과

함정오,안규동,황규윤,이병국,이성수,정두신 가톨릭대학산업의학센타 산업의학연구소 1992 韓國의 産業醫學 Vol.31 No.3

To investigate the effect of environmental measurement on the improvement of working condition in small and medium sized industries and to evaluate the usefulness of this measurement which is covered by Occupational Safety and Health Act for the protection of workers from hazardous working condition, authors selected 107 small and medium sized manufacturing industries mainly from Chunan area and partly from lead using industries which were in special contract of agent specific occupational health service with Institute of Industrial Medicine, Soonchunhyang University. Environmental measurements were provided twice in interval of 6 months to study industries. At the end of second measurement questionnaires were collected to check the usefulness of this measurement for the workers and industries itself. The results obtained were as follows: 1. Out of 107 manufacturing industries, the most frequently measured index of harmful agent in environmental measurement was noise, and the next indices were dust, organic solvents and special chemicals in descending order. While the excess rates of measurement over Permissible Exposure Level(PEL) in the first measurement were 19.3% in noise, 22.8% in dust, 14.3% I organic solvents and 20.3% in special chemicals measurement, those in second measurement were 26.0% in noise, 14.7% in dust, 10.0% in organic solvents and 29.5% in special chemicals measurement, respectively. 2. The supply rate of protective equipment and the labeling condition of health and safety poster in the later period of study were improved than early period. 3. Most persons in charge of health and safety management(97.2%) had engaged in other administrative works and only 2.8% of study industries had independent occupational safety and health personnels who engaged only in health and safety of workers. 4. The purpose of environmental measurement answered by the eligible of persons each industries was to report at the regional office of labor affair. Only 7 out of 107 industries answered that their measurements were for the real improvement of working condition and 3 industries for the fulfilment of requirement of trade union. 5. While 86.0% in industries (92/107) felt the report of environmental measurement was helpful to set up protective equipment program to prevent workers from harmful condition, 66.4% in industries answered that it was useful for the establishment of health education program. The measurement of environmental conditions were also useful for the installation of ventilatory system of workplace, for the isolation of work process and for the improvement of work process. But 8.4% in industries answered that it was not useful at all.

ROC 분석을 이용한 ν-glutamyltranspeptidase와 대사증후군과의 관련성 평가

김용배,함정오 순천향의학연구소 2007 Journal of Soonchunhyang Medical Science Vol.13 No.1

This study was accomplished to find out the relationship between γ-glutamyl transpeptidase(γ-GTP) and metabolic syndrome, and to suggest the optimal positive cut off point of γ-GTP using receiver operating characteristic(ROC) analysis. Study subjects were 171 women who participated in health screening at health promotion center in Soonchunhyang Cheonan hospital in 2006. We measured waist circumference, blood pressure, fasting glucose, triglyceride, high density lipoprotein cholesterol and γ-GTP. ROC analysis showed an area under the curve(AUC) of 0.870(95% confidence interval : 0.801 - 0.938), indicating an excellent classification performance of the model. The sensitivity of 88% and specificity of 81% was achieved at the optimal cut off point of γ-GTP around 20.5 U/L. In conclusion, γ-GTP could be used as a screening test for diagnosis of metabolic syndrome in nondrinker.

ROC 분석을 이용한 y -glutamyltranspeptidase와 대사증후군과의 관련성 평가

김용배,함정오 순천향의학연구소 2007 Journal of Soonchunhyang Medical Science Vol.13 No.1

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기상변화에 의한 기관지천식 발생빈도 분석에 지리정보체계의 유용성

김용배,함정오 순천향의학연구소 2007 Journal of Soonchunhyang Medical Science Vol.13 No.1

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醫療保險制度의 變化에 따른 醫療利用 樣相과 病床利用度 比較硏究

최병록,함정오,김화성,이병국 순천향의학연구소 1996 Journal of Soonchunhyang Medical Science Vol.2 No.2

This study was conducted to identify the effects of rural-fishing village health insurance system and the whole national health insurance system on the number of out-patient and in-patient cases and the hospital bed utilization, and the number of hospital persons in a university located in Choong Chung Nam Do. The results were as follows. 1. The number of out-patients was increased by 6.8% and 18.8% after the implementation of the rural fishing village health insurance system and the whole national health insurance system respectively. The number of out-patient visit cases was increased by 31.5% and 63.5% after implementation of the rural fishing village health insurance system and the whole national health insurance system respectively. 2. The number of in-patients was increased by 13.8% and 22.8% after the implementation of the rural fishing village health insurance system and the whole national health insurance system respectively. The number of bed days was increased by 27.1% and 32.8% after the implementation of the rural fishing village health insurance system and the whole national health insurance system respectively. 3. The hospital bed utilization rates were 77.3% and 98.4% before and after the rural fishing village health insurance system respectively, and 102.6%, after the whole national health insurance system. The bed rotation rate was increased from 23.6 times before the rural fishing village health insurance system to 27.0 times after the system. After the whole national health insurance program, it was also increased to 29.1 times. The average length of stay was 11.9 days before the rural fishing village health insurance system and 13.3 days after that, and 12.9 days after the whole national health insurance system. 4. Before the rural fishing village health insurance system the physicians per 100 beds was 19.0 persons. The physicians per 100 beds was increased to 25.2 persons and 29.3 persons, after the rural fishing village health insurance system and the whole national insurance system respectively. Before the rural fishing village health insurance system the nurses per 100 beds was 26.8 persons. The nurses per 100 beds was increased to 35.4 persons and 38.3 persons, after the rural fishing village health insurance system and the whole national health insurance respectively. Before the rural fishing village health insurance system the manpower per 100 beds was 101.6 persons. The manpower per 100 beds was increased to 128.6 persons and 138.9 persons, after the rural fishing village health insurance system and the whole national insurance respectively.

일부 인쇄회로기판 납땜근로자들의 눈, 호흡기, 피부의 증상에 대한 조사연구

유재영,우극현,김진석,함정오,최태성,하봉구,정상재,박신구,김일룡 大韓産業醫學會 2001 대한직업환경의학회지 Vol.13 No.4

목적 : 이 연구는 납점작업자를 대상으로 납점작업으로 유발될 가능성이 높은 눈, 호흡기, 피부 등의 증상호소율 및 노출강도에 따른 관련성을 파악하기위해 수행되었다. 방법 : 연구참가자 146명중 연구목적에 적합한 20명을 제외한 126명을 대상으로 '눈이 가렵고 충혈됨', '코가 가렵거나 파가움', '재채기', '콧물'. '코막힘' , '목이 따끔거림' , '목에 무언가가 걸려있는것 같음' , '갑자기 연속적인 기침을 함' , '운동 시에 다른 사람에 비해 숨이 가쁨', '숨을 쉴 때 쌕쌕하는 소리가 남', '가래가 끓음', '손이나 안면에 가려움을 느낌' , '안면에 여드름이 날' '손이나 안면에 붉은 반점이 남' 등 14가지 증상에 대한 경험유무와 혈중연농도, 납점작업의 건강위험요인에 대한 지식상태 등을 조사하였다. 결과 : 조사된 14가지의 증상 중, '갑자기 연속적인 기침을 함'이 하루 납점시간 4시간 이상인 군아서 4시간 미만인 군보다 유의하게 증상호소율이 높았으며, 다른 증상의 경우 하루 납땜시간에 따라 유의한 결과를 보이지 않았다. 납땜작업의 건강위험요인에 대한 질문에 12.8 %가 플럭스에 의한 건강위험을 지적하였다. 전체 대상자의 평균 혈중연농도는6.05 rg/dL였으며, 히고치는 15.50 rg/dL이었다.결론 : 납땜작업자에게 호흡기 증상의 위험이 높을 가능성이 있으며, 납땜작업의 건강위험에 대한추가적인 연구와 납점작업자들을 대상으로 납점작업에 의해 유발될 수 있는 건강장해에 대한 적극적인교육 및 홍보활동을 필요로 한다. Objectives : This study was conducted to evaluate the prevalence of ocular, respiratory and skin symptoms among solderers and to investigate the relationship between symptom prevalence and exposure intensity. Methods : We analyzed 126 eligible participants out of a population of 146 male solder-ers who completed the symptom questionnaires. Fourteen symptoms including 'itchy and red eyes', 'itchy or prickly nose', 'sneezing', 'rhinorrhea', 'blocked nose', 'prickly throat', 'foreign body sensation in throat', 'sudden bouts of coughing', 'exertional breathlessness', 'wheezing', 'sputum production', 'itchy face or hands', 'acneiform erup-tions on the face' and 'red spots on the face or hands' were contained. Blood lead levels of all the 126 participants were tested and the participants' own assessments of the health risk of soldering were collected. Results : Of the 14 investigated symptoms, 'sudden bouts of coughing' was significantly more prevalent in solderers who worked 4 hours or more a day than those who worked less than 4 hours a day, as for the other symptoms, there were no significant differences in the prevalences related to daily soldering hours. 2.8% of the solderers considered the risk of flux exposure to be serious. The mean blood lead bevel was 6.05 μg/dL (maximum 15.50 μg/dL). Conclusions : Soldering may increase the risk of respiratory symptoms. Further invert tigations on the hazards of soldering processes are warranted and solderers should be educarted on these hazards.