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'Chinese Herb Nephropathy'란 용어는 올바른 것인가?
최기림,이진신,장원만,안영민,안세영,두호경,이병철,Choi, Ki-Lim,Lee, Jin-Sin,Jang, Won-Man,Ahn, Young-Min,Ahn, Se-Young,Doo, Ho-Kyung,Lee, Byung-Cheol 대한한방내과학회 2000 大韓韓方內科學會誌 Vol.21 No.4
After Vanherweghem J-L reported the rapidly progressive interstitial renal fibrosis that developed in patients taking the slimming preparation compounded with chinese Herb in Belgium 1993. Chinese Herb Nephropathy(CHN) has become known as a new renal disease, CHN is described as the decrease of urinary renal enzyme, neutral endopeptidase(NEP). N-acetyl-${\beta}$-Dglucosaminidase(NAG). increase of urinary low molecular protein, ${\alpha}$1-microglobulin, ${\beta}$2-microglobulin. clara cell protein(CC16), retinol-binding protein(RBP) in clinical findings, and the proximal tubular atrophy, interstitial fibrosis. urothelial atrophy. glomerular sclerosis in histology, Because CHN was caused by Chinese herb contained in slimming preparation, western medical doctors have thought that all Herb medicine might have caused renal disease and prohibit the taking of any Herb medicine, However. CHN was actually caused by the aristolochic acid contained in some Herb medicines. Aristolochia manshuriensis, Aristolochia fang chi, which is the substitutions of Akebia quinata, Stephania tetrandra has being used in clinical. Aristolochia manshuriensis. Aristolochia fang chi were different with Akebia quinata. Stephania tetrandra in botany, and it have not been classified with medicines in Oriental medicine, That is, the aristolochic acid, not Herb medicines. causes CHN, So, Chinese Herb Nephropathy should be changed to Aristolochic acid Nephropathy.
한국에서의 부녀의 세대 간 소득 이동성: 선별적 결혼의 역할
최기림 ( Kilim Choi ),안태현 ( Taehyun Ahn ) 한국여성경제학회 2015 여성경제연구 Vol.12 No.2
본 연구는 한국노동패널(KLIPS) 자료를 사용하여 딸의 세대 간 소득탄력성을 추정하고 세대 간 소득이동성에서 선별적 결혼의 역할이 유효한가에 대한 분석을 시도했다. 연구결과 딸의 세대 간 소득탄력성은 0.172였고 동일한 방법으로 얻은 아들의 세대 간 소득탄력성 추정치와 비교해 보았을 때, 딸의 세대 간 소득이동성이 아들에 비해 더 낮은 것으로 나타났다. 또한 기혼인 딸을 표본으로 분석한 결과, 남편의 소득과 장인어른의 소득사이에 상당한상관관계가 존재함을 알 수 있었고 선별적 결혼의 경향이 부모세대와 자녀세대간의 경제력대물림을 더 확대시키는 경로가 될 수 있음이 발견되었다. 또한, 부녀간 간 소득 이동성에부부간의 유사학력에 따른 선별적 결혼이 중요한 역할을 할 수 있음을 알 수 있었다. This study estimates intergenerational income mobility among daughters using Korean Labor and Income Panel Study(KLIPS) and investigates the role of marital sorting. The estimated intergenerational income elasticity among daughters was 0.172 which is larger than that of sons. We also find that there is a strong correlation between the income of father-in-law and that of son-in-law, and that marital sorting plays an important role in intergenerational income mobility. The results also suggest that marital sorting by education level can be a key factor of intergenerational income mobility.
수풍순기환(搜風順氣丸)이 내당능장애 환자와 경증 당뇨병환자의 혈당조절에 미치는 영향
권영구,최기림,이진신,안영민,안세영,두호경,이병철,Kwon, Young-Gu,Choi, Ki-Lim,Lee, Jin-Sin,Ahn, Young-Min,Ahn, Se-Young,Doo, Ho-Kyung,Lee, Byung-Cheol 대한한방내과학회 2001 大韓韓方內科學會誌 Vol.22 No.3
Purpose : Impaired glucose tolerance (IGT) was standardized in 1979 by the National Diabetes Data Group and the World Health Organization as a risk factor for type 2 diabetes, replacing groups such as 'borderline' and 'chemical' diabetes. The main clinical significance of IGT is as a risk factor for type 2 diabetes and as a risk factor for cardiovascular disease and as a component of the metabolic syndrome. In 1997 the American Diabetes Association(ADA) was proposed the new classification and diagnostic criteria for diabetes, which is strict with the diagnostic baseline of Diabetes from 140mg/dl to 126mg/dl. And it's main purpose is to prevent chronic complications by early diagnosis and treatments. In the oriental medicine, Supungsunkihwan has been used in treatments of Diabetes including IGT & NIDDM, however there is not enough studies about the its objective hypoglycemic effect. so in order to investigate whether there is hypoglycemic effect of Supungsunkihwan, clinical studies were performed with IGT and mild NIDDM patients. Methods : Prior to the study, fasting blood sugar(FBS) and postprandial 2hrs(PP2hrs) glucose were checked. In addition, ECG, cholesterol, TG, HbA1c levels were measured, and the dinical characteristics of patients that can be influence to the blood sugar level such as age, gender, rest type, diet type were surveyed. Supungsukihwan was administered for 7 days, and FBS & PP2hrs were measured again after the therapy. Result : PP2hrs glucose levels were decreased by the administration of Supungsunkihwan. And It's hypoglycemic effects has the correlation with age. That is, the more age increase, the more hypoglycemic effect decrease. Conclusion : Supungsukihwan has hypoglycmic effects on IGT & mild NIDDM patients and it is more effective when administrated to young patients relatively.
이진신,이병철,장원만,안영민,안세영,두호경,최기림,Lee, Jin-Sin,Lee, Byung-Cheol,Jang, Won-Man,Ahn, Young-Min,Ahn, Se-Young,Doo, Ho-Kyung,Choi, Ki-Lim 대한한방내과학회 2000 大韓韓方內科學會誌 Vol.21 No.4
Vesicoureteral reflux(VUR) is a state that urine regurge from bladder to ureter and kidney because of congenital, structural, functional abnormality of ureterovesical junction and lower urinary tract than bladder. It may be the primary cause of recurrent urinary tract infection(UTI) in chindhood, If urine regurge with UTI, it can cause renal damage, leading to scar formation, hypertension, chronic renal failure, But upper complications can be prevented by early diagnosis and proper treatment of VUR and UTI, so clinician must focus on them in treatment of VUR. We had experienced a case of recurrent UTI with VUR regardless of consistent antibiotics therapy in 7 years old boy, Chief complain was urinary frequency, The symptom of urinary frequency was successfully treated by herb medicine(Gamijihwag-tang), So, we report this case with a brief review of related literatures.