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          The Inhibitory Effects of Ahnjeonbaekho-tang on FRTL-5 Cell Proliferation and Thyroxine Synthesis

          안세영,Kang, Shin-Ik,Lee, Byung-Cheol,Ahn, Young-Min,Doo, Ho-Kyung,Ahn, Se-Young 대한한방내과학회 2006 大韓韓方內科學會誌 Vol.27 No.3

          Objective : Graves' disease, the most common cause of hyperthyroidism, is an autoimmune disorder associated with autoantibodies to the TSH receptor. The clinical features of Graves' disease are goiter and hypermetabolic symptoms induced by excessive hormones. Antithyroid drug therapy is the first-line treatment for Graves' disease in Korea, Japan and European countries. Yet in spite of a long period and high-dose of treatment, it is hard to achieve remission because of adverse effects, frequent recurrence and resistance to antithyroid drugs. Recently, it has been reported that the abnormal thyroid hormone and clinical symptoms of Graves' disease were reduced by Ahnjeonbaekho-tang (AJBHT). Methods : To investigate the effectiveness and action mechanism of AJBHT, we studied the influence of AJBHT on FRTL-5 thyroid cell proliferation, DNA synthesis and expression of T4, TSH, cAMP, Tg and TPO mRNA. Results : AJBHT significantly inhibited the FRTL-5 cell proliferation, DNA synthesis, T4 synthesis, cAMP production and the expression of Tg mRNA in comparison with control and MMI. Conclusions : These results suggest that AJBHT may inhibit the cell proliferation and DNA synthesis by regulating the cAMP, and suppress the T4 synthesis by modulating Tg mRNA expression and cAMP synthesis, and that it may be useful agent for treating the goiter and hormone abnormality of Graves' disease.

        • 堤大川 流域 畓用水의 反復利用

          안세영,이근후,Ahn, Se-Young,Lee, Keun-Hoo 한국농공학회 1991 韓國農工學會誌 : 전원과 자원 Vol.33 No.3

          To investigate the status of repeated use of irrigation water observations of irrigation water were made on dry days during the irrigation periods in 1986 and 1987 crop year. The total area of studied site is 1,441 ha. The site is a major portion of Jedaecheon basin which is located in Bubuk-myeon, Miryang-gun, Gyeongnam Province. The studied area was subdivided into six small blocks. The inflow and outflow of daily irrigation water for these subdivided blocks were checked. Obtained results are as follows : 1. The over all possible ratio of the repeated use of irrigation water in studied area was 48.3%, which means that approximately one half of the surface flow was possible to be repeatedly used as irrigation water in this area. 2. The ratio of repeated use of irrigation water in sloppy paddy area was 4.29%, whereas, the ratio was 21.97% in the plain area. The average figure of this ratio over studied area was estimated as 17.43%.

        • 리튬이차전지 난연성 전해액 첨가제로서의 Tris(2,4,6-trimethoxyphenyl)Phosphine의 열적, 전기화학적 특성

          안세영,김기택,김현수,Ahn, Se-Young,Kim, Ke-Tack,Kim, Hyun-Soo 한국전기전자재료학회 2008 전기전자재료 Vol.21 No.12

          Thermal and electrochemical properties were discussed with tris(2,4,6-trimethoxyphenyl)Phosphine (TTMPP) as a flame retradant additive for Li-ion battery. TTMPP showed excellent thermal stability with charged cathodes. Addition of 1 wt.% of the additive to the electrolyte improved the thermal stability without damaging the performance of the battery. The oxygne evolution reaction delayed nearly by $60^{\circ}C$. The capacity retention ratio in cycle life tests of the battery with 1 wt.% TTMPP was slightly improved comparing to the no additive cells.

        • KCI등재

          리튬이온전지용 난연성 첨가제(TCP, TFPP)의 전기화학적 특성

          안세영,김기택,김현수,남상용,Ahn, Se-Young,Kim, Ke-Tack,Kim, Hyun-Soo,Nam, Sang-Yong 한국전기전자재료학회 2007 전기전자재료학회논문지 Vol.20 No.9

          Flame retardant(FR) properties were investigated with tricredyl phosphate(TCP) and tris(pentafluorophenyl)phosphine(TFPP) as additives for lithium-ion batteries. Thermal stability was improved with additives in $Li/LiNi\frac{1}{3}Mn\frac{1}{3}Co\frac{1}{3}O_2$ cells comparing to non-additive electrolytes. Oxygen evolution reaction of the cathode material was delayed to up $55^{\circ}C$, from $275^{\circ}C\;to\;330^{\circ}C$. Electrolytes with the 1 wt.% additives provided good FR properties while the resonable battery performance is maintained.

        • KCI등재

          리튬이차전지 난연성 전해액 첨가제로서의 Tris(2,4,6-trimethoxyphenyl)Phosphine의 열적, 전기화학적 특성

          안세영,김기택,김현수,Ahn, Se-Young,Kim, Ke-Tack,Kim, Hyun-Soo 한국전기전자재료학회 2008 전기전자재료학회논문지 Vol.21 No.12

          Thermal and electrochemical properties were discussed with tris(2,4,6-trimethoxyphenyl)Phosphine (TTMPP) as a flame retradant additive for Li-ion battery. TTMPP showed excellent thermal stability with charged cathodes. Addition of 1 wt.% of the additive to the electrolyte improved the thermal stability without damaging the performance of the battery. The oxygne evolution reaction delayed nearly by $60^{\circ}C$. The capacity retention ratio in cycle life tests of the battery with 1 wt.% TTMPP was slightly improved comparing to the no additive cells.

        • KCI등재

          대학생 자살생각 관련변인에 대한 메타분석

          안세영(Se Young Ahn),김종학(Jong Hak Kim),최보영(Bo Young Choi) 한국심리학회 2015 한국심리학회지 학교 Vol.12 No.3

          본 연구는 대학생 자살생각과 관련된 지난 10년간의 선행연구를 바탕으로 자살생각 관련변인들의 효과크기를 메타분석을 통해 살펴보았다. 분석결과를 통해 본 연구는 대학생 자살생각과 관련된 후속 연구의 방향을 제시하고, 대학생의 자살 예방을 위한 교육 및 상담현장에 실질적인 자료를 제시하고자 하였다. 이를위해 연구 대상 자료는 한국교육학술정보원(KERIS), 한국학술정보원(KISS)과 국회도서관의 데이터베이스에서 2005년 1월부터 2015년 2월까지 발행된 대학생 자살생각과 관련이 있는 변인들과의 상관관계를 제시한 국내 석․박사논문 및 학술지 게재 논문 72편을 최종 연구대상으로 선정하였다. 연구결과, 첫째, 대학생 자살생각 관련 변인 중 유발변인군의 하위변인은 11개, 억제변인군의 하위변인은 6개로 분류되었다. 둘째, 대학생의 자살생각 유발변인군의 하위변인 중 우울, 부정적 정서, 무망감 순으로 큰 효과크기가 나타났고, 그 외에도 역기능적 가족의사소통, 부적응적 완벽주의, 생활스트레스, 부적응적 인지적 정서조절, 충동성, 취업스트레스, 정서중심 스트레스 대처방식, 문제음주 순으로 중간 효과크기가 나타났다. 셋째, 대학생 자살생각 억제변인군의 하위변인으로는 자아존중감이 가장 큰 효과크기를 가진 것으로 나타났고, 그 다음으로는 자아정체감, 애착, 자아탄력성, 사회적 지지 순으로 중간 크기의 효과를 가진 것으로 나타났다. 그리고 문제중심 스트레스 대처방식은 가장 작은 효과크기가 있는 것으로 나타났다. 즉, 대학생 자살생각 유발변인군 중 특히 큰 효과크기를 나타내는 변인은 우울, 부정적 정서, 무망감이었고, 억제변인군 중 큰 효과 크기를 나타내는 변인으로는 자아존중감으로 확인되었다. 이러한 연구결과를 중심으로 본 연구의 의의 및 시사점과 제한점, 후속 연구를 위한 제언을 논의하였다. The purpose of this study was to conduct a systematic review of the previous research on suicidal ideation among college students. The meta-analysis was used to analyze dissertations and academic journals published in Korea from the year of 2005 to 2015 which dealt the variables of college students" suicidal ideaton. Main results of this study were as follows: First, the variables related to suicidal ideation among college students were classified into 11 variables of triggering factors and 6 variables of suppressing factors. Second, the most influential triggering variable was depression, which was followed by negative emotion, hopelessness, dysfunctional family communication, maladaptive perfectionism, life stress, maladaptive cognitive emotion regulation, impulsivity, job-seeking stress, emotion-focused stress coping style, and problem drinking, respectively. Third, the most influential suppressing variable was self-esteem. And it was followed by self-identity, attachment, ego-resilience, social support, and problem-focused stress coping style. In conclusion, the results of this study can be applied to educational and counseling program for the prevention of college students" suicide. Limitations to the current study and recommendations for future research are discussed.

        • 유사량(流砂量) 산정(算定)에 관(關)한 연구(硏究) (밀양강(密陽江)을 중심(中心)으로)

          안세영 ( Se Young Ahn ),민병형 ( Byung Hyung Min ) 한국농공학회 1980 韓國農工學會誌 : 전원과 자원 Vol.22 No.4

          This study is carried out to estimate the rate of sediment transportation both to measure the amount of suspended and bedload sediment that moves on or near the river bed and passes through the cross section of a river in unit time, with suspended and bed load samplers used for the Milyang river and to determine the most satisfactory and convenient formula of some formulas for sediment discharge by comparing the measured rate with the calculated rate. The results of this study are summarized as follows; 1) The interrelationship (1) between the total discharge and the total sediment discharge (2) between discharge and suspended sediment load and (3) between discharge and bed load in the Milyang river are (1) i) 4≤Q≤100 C.M.S. Q<sub>T</sub>=0.00272 Q<sup>0.70</sup> (kg/sec) ii) 150≤Q≤800 C.M.S. Q<sub>T</sub>=0.4807 Q<sup>0.46</sup> (kg/sec) (2) Q<sub>s</sub>=0.07576 Q<sup>1.02</sup> (kg/sec) (3) Q<sub>B</sub>=0.00957 Q<sup>0.44</sup> (kg/sec) 2) The rate of suspended sediment load to total sediment discharge is found to be about; 99%. The suspended load is shown to be almost wash load which consists of silt and clay. 3) The relation between the total discharge and the suspended sediment load that are measured at three medium and small rivers in Korea is Q<sub>s</sub>=0.13831 Q<sup>0.97</sup> (kg/sec) 4) Brown's formula is determined to be the most convenient formula for application and comparison with observed data obtained for the Milyang river.

        • KCI등재
        • 제대천(堤大川) 유역(流域) 답지대(畓地帶)의 물수지(收支)

          안세영 ( Ahn Se Young ),이근후 ( Lee Keun Hoo ) 한국농공학회 1990 韓國農工學會誌 : 전원과 자원 Vol.32 No.3

          To investigate the status of irrigation water use and the degree of repeated use of irrigation water, observations for water balance analysis were made during the irrigation periods in 1986 and 1987 crop year. The total area of studied site is 1,441 ha. The site is a major portion of Jedaecheon basin which is located in Bubuk-myeon, Miryang-gun, Gyeongnam Province. The studied area was subdivided into six small blocks. The water balance analysis for these subdivided blocks were carried out considering characteristics of each block. Obtained results are as follow: 1. In mountainous sloppy paddy area(less than 7% slope), the surface inflow was 5A mm/day in average that is one third of the surface inflow into plain paddy area ; 16.7 mm/day. 2. The surface inflows at the vegetative stage and the ripening stage were 15.5 mm/day and 10.4 mm/day, respectively. Those figures were larger than the actual consumptive use at respective same stages ; 13.3 mm/day and 9.2 mm/day, respectively. Whereas, the surface inflow at generative stage was 12.5 mm/day which was less than 14.0 mm/day ; the actual consumptive use. 3. The range of the variation of water storage term was 1 mm/day. This means that there were no change in depth of ponded water on paddy fields. The relationship between the variation of water storage(△S) and the variation of ground water table(H) could be expressed as follow: : △S=0.14H+0.26 4. The ground water inflow: into the transition region ; paddy fields which are located continuously from the mountainous area to the plain area, was larger than the out flow from this region, in general. Rowever, in the plain region where the ground water utilization was predominant, the ground water outflow from this region was larger than inflow: to this region. The relationship between the ground water flow(G<sub>2</sub>- G<sub>1</sub>) and the consumptive use in large paddy area(D<sub>1</sub>-D<sub>2</sub>) could be expressed as follow: (G<sub>2</sub>-G<sub>1</sub>) =0.95(D<sub>1</sub>-D<sub>2</sub>) -3.79.

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