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실시간 네트워크 패킷 분석을 위한 Apache Spark 환경 구성
조용아(Yong-Ah Cho),안재훈(Jae-Hoon An),손재기(Jae-Gi Son) 대한전자공학회 2015 대한전자공학회 학술대회 Vol.2015 No.11
Apache Hadoop is widely known as Big Data platform. Recently there is increasing the need to process data in real time. But there is a limit to process a batch mode as Hadoop. In order to solve the this problem, Storm and spark processing platform with real-time streaming functionality was introduced. In this paper we describe the environment configured to analyze the incoming network packets in real time using a streaming, one of the several functions of the spark.
미성년자와 성인에서의 안드로겐탈모증의 임상적 차이 분석
조영아 ( Young Ah Cho ),손형석 ( Hyung Seok Son ),이지수 ( Ji Su Lee ),김진희 ( Jin Hee Kim ),최용범 ( Yong Beom Choe ),안규중 ( Kyu Joong Ahn ),이양원 ( Yang Won Lee ) 대한피부과학회 2021 대한피부과학회지 Vol.59 No.9
Background: Androgenetic alopecia (AGA) is characterized by terminal hair miniaturization, which progressively decreases hair density and thickness. Genetic predisposition and the role of androgen in AGA have been widely accepted; however, its definite mechanism has not been clarified. AGA may also occur in adolescents, although its clinical characteristics including the disease prevalence have not yet been fully established. Objective: To analyze the clinical differences of AGA between adolescents and adults. Methods: Six-hundred fourteen patients with AGA were recruited and information about age, sex, and family history, comorbidities were collected. Results: A total of 74.5% of adolescents and 66.4% of adults had family history of AGA, with “paternal only” as the most common pattern. A total of 27.3% of adolescents and 44.5% of adults had comorbidities, with seborrheic dermatitis being the most common. Other common comorbidities were acne, folliculitis, and atopic dermatitis in adolescents, dyslipidemia, hypertension, mood disorder, and diabetes mellitus in adults. A total of 12.7% and 15.0% of adolescents and adults, respectively, had abnormal serum testosterone levels, and 5.5% of adolescents and 7.5% of adults had abnormal serum dehydroepiandrosterone sulfate (DHEA-S) levels. Regardless of age, the proportion of patients with abnormal testosterone levels was higher in the female group than in the male group. Conclusion: AGA showed paternal predominance in family history regardless of sex or age, suggesting paternal history as an important factor of AGA. Testosterone and DHEA-S abnormalities were found in patients with AGA, indicating a need for further studies on therapeutic effects associated with differences in hormonal profiles. (Korean J Dermatol 2021;59(9):693∼698)
전신흥반루푸스 환자에서 혈청 Osteoprotegerin 증가
신용주 ( Yong Ju Shin ),홍경희 ( Kyung Hee Hong ),유승아 ( Seung Ah Yoo ),최진정 ( Jin Jung Choi ),김완욱 ( Wan Uk Kim ),조철수 ( Chul Soo Cho ) 대한류마티스학회 2006 대한류마티스학회지 Vol.13 No.3
Objective: To determine the serum levels of soluble osteoprotegerin (OPG), decoy receptor of receptor activator of nuclear factor kB ligand (RANKL), in patients with systemic lupus erythematosus (SLE) and to assess the its relationships with certain clinical manifestations. Methods: Serum levels of OPG in 60 patients with SLE and 30 healthy controls were determined by enzyme-linked immunosorbent assay. At the time of serum sampling, clinical manifestations and lupus disease activity index (SLEDAI) were assessed. Results: Serum levels of OPG in 60 patients with SLE were significantly higher than in 30 healthy controls (1,058±699 versus 806±113 pg/mL, p=0.008). Patients with active disease had higher levels of OPG levels than those with inactive disease (1,355±837 versus 760±113 pg/mL, p<0.001). Serum OPG levels correlated with SLEDAI (γ=0.588, p<0.0001), anti-dsDNA antibody titers (γ=0.337, p=0.009) and serum MCP-1 levels (γ=0.485, P<0.0001). In particular, serum OPG levels were found to be significantly increased in patients with neurological manifestation compared to those without (1,504±1,152 versus 918±376 pg/mL, p=0.004). Conclusion: The results of this study suggest that serum OPG levels are increased in patients with SLE. Serum OPG has a role as marker for disease activity and its increased levels reflect the involvement of neurological manifestation.
원용재(Yong-Jae Won),양창인(Chang-Ihn Yang),조영찬(Young-Chan Cho),최임수(Im-Soo Choi),김명기(Myeong-Ki Kim),정응기(Eung-Gi Jeong),이점호(Jeom-Ho Lee),이상복(Sang-Bok Lee),백만기(Man-Kee Baek),홍하철(Ha-Cheol Hong),안억근(Eok-Keun Ah 한국육종학회 2016 한국육종학회지 Vol.48 No.3
The Misomi is a rice variety derived from a cross between ‘Sobi’ which has adaptability of low fertilizer cultivation and SR21110 (Ilpum/Jinbu19) by the rice breeding team at National Institute of Crop Science, RDA in 2013. The heading date of ‘Misomi’ is August 14 and six days later than check variety, ‘Hwaseong’. It has 83 cm of culm length and 121 spikelets per panicle. It showed weaker cold tolerance than that of ‘Hwaseong’ during exposed to cold stress. ‘Misomi’ showed resistance to blast disease, K1, K2 and K3 race of bacterial blight and stripe virus, but susceptibility to K3a race, other viruses and planthoppers. The milled rice of this variety exhibits translucent, clear non-glutinous endosperm and short grain shape. It has low protein content (6.2%) and similar amylose content (19.4%) to that of ‘Hwaseong’. ‘Misomi’ showed better palatability index of cooked rice than that of ‘Hwaseong’. Particulary, ‘Misomi’ showed excellent processing adaptability than ‘Chucheong’ and ‘Hwaseong’ on palatability index of cold and aseptic cooked rice. Its milled rice recovery rate is similar to those of ‘Hwaseong’. However, whole grain rate of milled rice is higher than that of ‘Hwaseong’. Misomi has 5.68 MT/ha of milled rice productivity in ordinary cultivation, which was 12% higher than that of ‘Hwaseong’. Misomi could be adaptable to the middle plain area and Midwest coast area in Korea (Grant No. 5635).
천연가스 개질형 30Nm³/hr급 수소스테이션 연구개발 현황
이영철(Lee, Young-Chul),조영아(Cho, Young-Ah),박달영(Park, Dall-Young),최정환(Choi, Chung-Hwan),김재동(Kim, Jae-Dong),송택용(Song, Taek-Yong),조병학(Cho, Byoung-Hak),김동혁(Kim, Dong-Hyeok),이중성(Lee, Jung-Sung),오영삼(Oh, Young- 한국신재생에너지학회 2006 한국신재생에너지학회 학술대회논문집 Vol.2006 No.06
수소는 청정에너지로서 미래에너지의 대안으로 여겨지고 있기 때문에 수소에너지 관련 기술은 미래 국가 경쟁력을 좌우할 것으로 예상되며 이러한 수소에너지의 핵심인 수소스테이션 관련 기술은 국가연료전지 시장을 비롯한 수소자동차 사업 전반에 커다란 영향을 미칠 것으로 예상되고 있다. 이에 따라 전 세계적으로 수소에너지를 차세대 에너지원으로 개발하기 위하여 전력을 다하고 있으며, 수소연료전지자동차 개발과 아울러 수소스테이션 개발에 대한 인프라 구축 및 실증연구가 본격적으로 이루어지고 있다. 국내에서도 가스공사를 비롯한 에너지 관련 기업에서 수소스테이션 건설이 추진되고 있으며, 본 연구에서도 수소인프라 구축의 일환으로 추진되고 있는 수소스테이션 개발 현황에 대하여 논의하고자 한다.
피부섬유아세포에서 저산소증에 의한 Connective Tissue Growth Factor의 발현
홍경희 ( Kyung Hee Hong ),유승아 ( Seung Ah Yoo ),강순숙 ( Soon Sook Kang ),신용주 ( Yong Ju Shin ),김완욱 ( Wan Uk Kim ),조철수 ( Chul Soo Cho ) 대한류마티스학회 2004 대한류마티스학회지 Vol.11 No.4
Objective: Connective tissue growth factor (CTGF) has been proposed to play a role in fibrotic process of systemic sclerosis. Since hypoxia was known to be associated with fibrosis in several profibrogenic conditions, we investigated whether CTGF expression in dermal fibroblast is regulated by hypoxia caused by microvascular loss. Methods: Dermal fribroblasts from patient with systemic sclerosis and normal controls were cultured in the presence of cobalt chloride (CoCl2), a chemical inducer of HIF-1α or hypoxic culture conditions. Expression of HIF-1α, VEGF and CTGF was evaluated by semiquantitative reverse transcription-polymerase chain reaction and Western blotting. Results: Scleroderma fibroblasts expressed increased levels of HIF-1α, VEGF and CTGF compared to normal dermal fibroblasts. Dermal fibroblasts exposed to various concentration of CoCl2 (1∼100μM) enhanced the expression of CTGF mRNA in dose-dependent fashion. Actinomycin D significantly blocked the hypoxia-mediated up-regulation of CTGF mRNA expression, whereas cycloheximide did not block the up-regulation. Up-regulation of CTGF by hypoxia was not mediated by endogenous production of transforming growth factor (TGF)-β. In time-kinetics study, dermal fibroblasts from scleroderma patients exhibited earlier peak expression of CTGF mRNA than those from normal dermal fibroblasts. In addition, simultaneous treatment of suboptimal concentration of CoCl2 and TGF-β exhibited the up-regulation of CTGF mRNA in additive fashion. Interferon-γ did not modulate the expression of CTGF mRNA induced by CoCl2, while the up-regulation of CTGF by TGF-β was downregulated by Interferon-γ in a dose-dependent fashion. Conclusion: These data indicate that hypoxia up-regulates the expression of CTGF in dermal fibroblasts and provide the evidence that hypoxia caused by microvascular alterations contributes the progression of fibrosis in systemic sclerosis by up-regulation of CTGF.