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치매 환자의 장기 요양 이용 현황 분석 및 생애 의료비 측정
정석종(Seok Jong Chung),이지은(Jee Eun Lee),김동욱(Dong Wook Kim),윤소라(So Ra Yoon),신동교(Dong Gyo Shin),최문영(Moon Young Choi),이준홍(Jun Hong Lee) 대한임상노인의학회 2021 대한임상노인의학회지 Vol.22 No.1
Background: To investigate the current status of long-term care services for patients with dementia and lifetime medical costs for dementia in South Korea. Methods: This study utilized the National Health Insurance Service-National Health Information Database (NHIS-NHID) from January 2013 to December 2017. The prevalence and incidence of dementia was estimated by extracting people who were diagnosed and treated with dementia (age≥45 years) from the database. The use of long-term care services by the elderly with newly diagnosed dementia was also investigated. Additionally, the lifetime medical expenses for dementia were estimated using data on a single year’s medical costs, population data, and a life table from Statistics Korea. Results: The prevalence of dementia increased from 2015 to 2017, while the incidence of dementia gradually decreased. Among the patients with newly diagnosed dementia, approximately 30% used the long-term care services, while 4th graders accounted for the highest proportion every year. The older the individual and the lower their income quartile, the shorter the time they took to apply for long-term care services after diagnosis of dementia. The total medical expenses per capita increased steadily every year, and the lifetime medical expenses were higher for women than men. Half of the lifetime medical costs of dementia occurred after 67 years of age for men and 83 years for women. Conclusion: This study suggests that medical, social, and political measures are needed to effectively manage the long-term care of service recipients and prepare for rising medical costs for dementia.
사람의 편평상피세포암 암줄기세포로 추정되는 분획에서 ATF3 발현 및 칼시뉴린 억제의 역할
정보영 ( Bo Young Chung ),김병욱 ( Byung Wook Kim ),이미우 ( Mi Woo Lee ),최지호 ( Jee Ho Choi ),김창덕 ( Chang Duk Kim ),장성은 ( Sung Eun Chang ) 대한피부과학회 2014 대한피부과학회지 Vol.52 No.10
Background: A previous study reported that calcineurin inhibition by cyclosporin A (CsA) showed tumor-enhancing effects through the induction of the ATF3 transcription factor and the associated suppression of p53. The development and aggressiveness of cutaneous squamous cell carcinoma (SCC) may be determined by cancer stem cell populations, which have self-renewing potential. Objective: To determine the role of ATF3 and calcineurin inhibition in the proliferation of SCC and evaluate the existence of putative SCC stem cells. Methods: We performed real-time PCR, fluorescence activated cell sorting, and clonogenicity assays in SCC13 cells under conditions of calcineurin inhibition by CsA or ATF3 and p53 overexpression. The relationships amongstcalcineurin inhibition, p53, and ATF3 were demonstrated by western blot analysis and transient transfection assays in SCC13 cells. Results: In putative stem cell populations of SCC13 cells enriched in self-renewal potential, p53 expression was lower than that in differentiated SCC13 cells. CsA treatment or ATF3 overexpression caused an expansion of stem cell populations. Additionally, p53 overexpression inhibited cellular proliferation and reduced clonogenicity in SCC13 cells. CsA treatment led to a decrease in p53 expression and an increase in ATF3 in SCC13 cells on western blots. SCC13 cells with CsA and small interfering RNA against ATF3 demonstrated lower cell viability than SCC13 cells with CsA only and SCC13 cells with CsA and small interfering control RNA after 14 days. Conclusion: Putative cancer stem cell populations and differentiated cell populations in SCCs are positively regulated by ATF3 and p53, respectively. (Korean J Dermatol 2014;52(10):692∼700)
개복 담낭절제술 후 오랜 기간 후에 발생한 혈액 담즙증
정지선 ( Jee Sun Jeong ),음영욱 ( Young Ook Eum ),장지혜 ( Ji Hye Jang ),정은 ( Eun Chung ),양현 ( Hyun Yang ),김현선 ( Hyun Seon Kim ),배일헌 ( Il Hun Bae ),박선미 ( Seon Mee Park ) 대한췌장담도학회 2014 대한췌담도학회지 Vol.19 No.1
A 77-year-old woman was admitted with 5 days history of melena. She had an open cholecystectomy 30 years ago. Abdominal computed tomography and duodenoscopy revealed massive hemobilia. Angiography showed right hepatic arterial fistula to common bile duct near the surgical clip. Embolization was done successfully and the patient recovered. We experienced a case of a massive hemobilia which was occurred after a long period of time since open cholecystectomy without pseudoaneurysmal change of the right hepatic artery. And we suggest the direct vessel injury and fistula between the bile duct and a blood vessel as a possible cause of hemobilia in this case. Korean J Pancreatobiliary 2014;19(1):42-46
보문 : 여성 월간지 화장품 광고 및 홍보 유형에 따른 화장품 구매행동
김희은 ( Hee Eun Kim ),정성지 ( Sung Jee Chung ),김동건 ( Dong Geon Kim ) 한국의류학회 2012 한국의류학회지 Vol.36 No.10
This study compares and analyzes cosmetics purchasing behavior according to the advertising and publicity implemented in women`s monthly magazines as well as determines effective marketing strategies for the cosmetics industry. First, cosmetics advertising and publicity in women`s monthly magazines can be classified into conventional advertising, advertorials, beauty news based on press releases, and beauty articles written by editors. In addition, consumer purchasing behavior has been examined in terms of use of information, purchasing intention, and purchasing experience. A study was conducted on women in their 20`s to 40`s in Seoul and Gyeonggi-do with 289 questionnaires used in the final analysis. Data were analyzed by common factor analysis, randomized block design, Bonferroni adjusted t-test, and multiple linear regression using SPSS 12.0/Windows. The results of the study can be summarized as follows. First, there was a difference in purchasing behavior according to types of cosmetics advertising and publicity in women`s monthly magazines. Second, cosmetics shopping orientations were classified into six factors (the pursuit of impulsive purchasing and trends, well-known brands, convenience, low prices, efficacy and brand loyalty). There were significant effects of shopping orientation on cosmetics purchasing behavior according to the type of advertisement and publicity in women`s monthly magazines.