Short Report : 피부 국소성 점액증 1예

이미우(Mi Woo Lee),최지호(Jee Ho Choi),성경제(Kyung Jeh Sung),문기찬(Kee Chan Moon),고재경(Jai Kyoung Koh) 대한피부과학회 2000 대한피부과학회지 Vol.38 No.5

Cutaneous focal mucinosis is usually a solitary, asymptomatic, flesh-colored to white papule or nodule located on the face, neck, trunk or extremities but never over the joint of the hands, wrists, or feet. Histopathologically, it is characterized by localized deposition of mucin and associated fibroblast proliferation in the upper dermis. We describe a case of cutaneous focal mucinosis on the forearm of a 58-year-old man. (Korean J Dermatol 2000;38(5):683~686)

결절성 근막염 , 16 예의 고찰

이미우(Mi Woo Lee),최지호(Jee Ho Choi),성경제(Kyung Jeh Sung),문기찬(Kee Chan Moon),고재경(Jai Kyoung Koh) 대한피부과학회 2001 대한피부과학회지 Vol.39 No.1

Background: Nodular fasciitis is a reactive fibroblastic or myofibroblastic proliferative lesion that clinically and histologically can be misdiagnosed as a sarcoma. It is not familiar with dermatologist. Objective: We performed the study to review the clinical and histological characteristics of nodular fasciitis. Method: We reviewed the clinical and histopathological findings in sixteen patients with nodular fasciitis who visited Asan Medical Center during 10 years from 1989 to 1999. Results: l. Of the 16 patients, male to female sex ratio was 6:10. The mean age of onset was 29.9 years. 2. The mean duration of symptom was 4.5 months and in five patients the duration was less than one week. 3. Most frequently the upper extremity was involved, followed by the cheek. The maximum diameters of the most lesions were less than 3cm. 4. Histopathologically, nine cases showed subcutaneous type, five cases showed intramuscular type, and one case was suspected as an intradermal type. 5. Thirteen lesions were totally excised, and two lesions were only partially excised. There was no recurrence after the mean follow-up period of 27 months in thirteen patients. Conclusion:Nodular fasciitis is a benign disease, treated by simple or wide excision. Therefore, in those instances of apparent recurrence, reevaluation of the initial tissue specimen and the clinical course is needed for a correct diagnosis. (Korean J Dermatol 2001;39(1): 1~6)

한국인에서의 피부 림프종의 임상 및 병리조직학적 연구 - 대한피부과학회 피부병리연구분과위원회 공동연구 -

이미우 ( Mi-Woo Lee ),고재경 ( Jai-Kyoung Koh ),권경술 ( Kyung-Sool Kwon ),김낙인 ( Nack-In Kim ),김상원 ( Sang-Won Kim ),김수남 ( Soo-Nam Kim ),김방순 ( Bang-Soon Kim ),김유찬 ( You-Chan Kim ),김종민 ( Jong-Min Kim ),명기범 ( Ki- 대한피부과학회 2003 대한피부과학회지 Vol.41 No.1

Background: The relative frequency and clinicopathologic characteristics of lymphomas vary according to geography and race. Data on the features of cutaneous lymphoma in Korea are limited. Objective . The aim of this study was to document the relative occ

한국인에서의 악성 흑생종에 대한 임상 및 병리 조직학적 연구 - 대한피부과학회 피부병리연구분과위원회 공동연구 -

이미우 ( Mi-Woo Lee ),고재경 ( Jai-Kyoung Koh ),권경술 ( Kyung-Sool Kwon ),김낙인 ( Nack-In Kim ),김상원 ( Sang-Won Kim ),김수남 ( Soo-Nam Kim ),김방순 ( Bang-Soon Kim ),김유찬 ( You-Chan Kim ),김종민 ( Jong-Min Kim ),명기범 ( Ki- 대한피부과학회 2003 대한피부과학회지 Vol.41 No.1

Backgorund ; Malignant melanoma in Korean has been increasing as in other countries, but there is no nationwide survey of malignant melanoma in Korea. Objective : The aim of this study was to document the clinical and histopathological features of cutaneo

켈로이드성 변화를 보인 결절성 근막염 1 예

이미우(Mi Woo Lee),최지호(Jee Ho Choi),성경제(Kyung Jeh Sung),문기찬(Kee Chan Moon),고재경(Jai Kyoung Koh),강숙경(Sook Kyoung Kang),배지영(Jee Young Bae) 대한피부과학회 2002 대한피부과학회지 Vol.40 No.2

Nodular fasciitis is a reactive myofibroblastic proliferative lesion and is frequently misdiagnosed as a sarcoma. Histopathologically, nodular fasciitis can be grouped into three subtypes based on their relation with the fascia: subcutaneous, fascial, intramuscular. The subcutaneous type is the most common type. Its histological appearance is quite variable, with lesions ranging from highly cellular pseudosarcomatous to myxoid proliferations, to hyalinized tumefactions with keloid-like strands of collagen. Herein we report a case of subcutaneous nodular fasciitis showing keloid-like, hylainized, and thickened collagenous change.

HMB - 45 염색에 음성을 보인 저색소성 세포성 청색모반 1 예

이미우(Mi Woo Lee),최지호(Jee Ho Choi),성경제(Kyung Jeh Sung),문기찬(Kee Chan Moon),고재경(Jai Kyoung Koh) 대한피부과학회 2002 대한피부과학회지 Vol.40 No.2

Blue nevus is a benign pigmented lesion of dermal melanocytes with a number of histologic and clinical variants. We report a variant of cellular blue nevus that is minimally pigmented. Immunohistochemistry showed the case to be strongly positive with S-100 protein, but negative with Ki-67 and HMB-45 antibody. There is a potential for hypopigmented cellular blue nevus to be confused with other benign nevus, such as intradermal nevus, Spitz nevus, and deep penetrating nevus and malignant melanoma.

경화부종의 임상 및 병리조직학적 연구

이미우(Mi Woo Lee),최지호(Jee Ho Choi),성경제(Kyung Jeh Sung),문기찬(Kee Chan Moon),고재경(Jai Kyoung Koh) 대한피부과학회 2002 대한피부과학회지 Vol.40 No.2

Background : Scleredema is a rare connective disorder with unknown etiology. There were no comprehensive studies about the clinical and histopathological features of scleredema in Korea. Objective : Our purpose was to find the clinical and pathological features of scleredema. Methods : The 31 patients with scleredema at our institution over ten years were retrieved. We reviewed medical records, clinical photographs, and histopathology slides of these patients, retrospectively. Results 1. The male to female ratio was 23:8 (2.9:1). 2. Most of the patients had the insidious onset and chronic localized lesion on the nape and upper back. 3. In sixteen patients (16/31, 51.6%), the diabetes mellitus was accompanied. In these patients, the male predominance (14/16, 87.5%) was significant. 4. The positive staining was in 75%(15/20) of the tissues with alcian blue or mucicarmine staining. 5. In four patients, localized electron beam therapy markedly improved the skin lesion without serious adverse effects. Conclusion : A preceding respiratory infection was uncommon. Almost all patients had insidious onset and chronic course. Diabetes mellitus was commonly accompanied, especially in male patients. Electron beam therapy appears to be effective in the treatment of scleredema.

만성 신부전 환자의 후천성 천공성 피부증에 대한 연구

이미우(Mi Woo Lee),최지호(Ji Ho Choi),성경제(Gyung Je Sung),문기찬(Gee Chan Moon),고재경(Jae Gyung Ko) 대한피부과학회 2000 대한피부과학회지 Vol.38 No.9

Background: Acquired perforating dermatosis (APD) is a skin disorder occurring in patients with diabetes mellitus and/or chronic renal failure requiring dialysis. Objective : The purpose of this study was to clarify the clinical and histhopathological features of APD. Method: Twelve patients with APD who had biopsies done at Asan Medical Center were retrieved for this study. Clinical data and histopathologic specimens were reviewed. Results and Conclusion: 1. Sex ratio was 3:1 (9 male: 3 female) and mean age of onset was 52.1 years. 2. All patients had pruritic umbilicated papules with central keratotic plugs. The most predilection site was trunk. 3. Nine patients had an associated underlying non-insulin dependent diabetes mellitus 4. Skin lesions had developed on pre-dialysis in three patients, and after mean duration of 3.3 years on dialysis in remaining nine. 5. Histopathological examinations revealed the features of perforating folliculitis, Kyrle's disease or reactive perforating collagenosis. But we did not find any specimen resembling elastosis perforans serpiginosa. 6. It makes sense to designate the diseases as acquired perforating dermatosis rather than as one of the separate perforating diseases.

유방외 Paget병의 임상적 연구

이미우(Mi Woo Lee),최지호(Ji Ho Choi),성경제(Gyung Je Sung),문기찬(Gee Chan Moon),고재경(Jae Gyung Ko) 대한피부과학회 2000 대한피부과학회지 Vol.38 No.8

Background: Extramammary Paget's disease (EMPD) is a rare skin neoplasm usually observed in apocrine-bearing regions. There were no comprehensive studies about the clinical features of EMPD in Korea. Objeetive: Our purpose was to study in detail the clinical findings of EMPD. Methods: The fifteen patients with EMPD at our institution over ten years were retrieved. Clinical records and pathology slides of the patients were reviewed retrospectively. Results: l. EMPD was seen more frequently in men than women (14:1 male:female ratio). 2. The most predilection site was penoscrotal area. 3. Thirteen percent of patients (2/15) with the disease had an associated underlying malignancy. 4. Twenty-two percent (2/9) of patients with wide excision had local recurrence during the follow-up period. Conclusion: EMPD in Korea may be characterized by male predominance and penoscrotal location. The incidence of concomitant malignancy may be lower than that in Caucasian. However, a search for internal malignancy and regular follow-up is still warranted.

Acral Persistent Papular Mucinosis 2예

이미우(Mi Woo Lee),최지호(Jee Ho Choi),성경제(Kyung Jeh Sung),문기찬(Kee Chan Moon),고재경(Jai Kyoung Koh) 대한피부과학회 2000 대한피부과학회지 Vol.38 No.2

We describe two cases of acral persistent papular mucinosis. The characteristic findings include discrete papules on the extensor surfaces of the hands and wrists, mucous deposits within the dermis, persistence or slow progression for several years. APPM may be considered as the disease entity in the same spectrum with lichen myxedematosus. (Korean J Dermatol 2000;38(2):236~239)