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      • KCI등재후보
      • SCOPUSSCIEKCI등재

        뇌실복강간 단락술의 합병증으로 생긴 뇌척수액 복수 - 증 례 보 고 -

        이병회,강성돈,김종문,Lee, Byoung Hoi,Kang, Sung Don,Kim, Jong Moon 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.11

        Ventriculoperitoneal(VP) shunting has been associated with a variety of complications. CSF ascites secondary to VP shunting is very rare. We report a case of 68-year-old man with VP shunt in whom subclinical peritoneal infection presented with ascites. The patient was treated successfully with antibiotics and removal of the shunt. CSF ascites complicating VP shunt is reviewed and the pathogenesis of this condition is discussed.

      • KCI등재후보

        Multiple Intracerebral Hemorrhages Associated with Cardiac Myxoma

        이병회,김태영,문성근,김종문 대한신경외과학회 2004 Journal of Korean neurosurgical society Vol.35 No.1

        The authors report a case of cardiac myxoma with simultaneous multiple intracranial hemorrhages. A 45-year-old man presenting with hemiparesis and seizure was found on brain computerized tomography(CT) scan to have intracranial hemorrhagic regions in both frontoparietal areas. Chest CT scan for searching primary focus of metastasis showed a mass in the heart, and subsequent echocardiogram showed a myxoma in the left atrium. Total resection of the brain lesions was carried out after cardiac operation. Although myxoma cells could not be found in specimens of the intracerebral lesions, coincidental hemorrhages were suspected to have occurred due to metastasis of cardiac myxoma. Key words:Myxoma;Metastasis;Multiple intracerebral hemorrhages.

      • KCI등재

        알코올중독과 감각추구 성향

        이병회,박상학,김상훈 大韓神經精神醫學會 1996 신경정신의학 Vol.35 No.1

        저자들은 알코올중독환자의 감각추구경향을 알아보고자 알코올중독환자 45명과, 정상대조군 45명에게 인구통계학적 질문과 감각추구척도, 그리고 음주관련 설문지를 실시하여 다음과 같은 결과를 얻었다. 1) 알코올중독 환자집단이 대조군보다 평균음주량과 최대음주량, 월평균 음주빈도, 법적 제재 경험 유무, 가족력의 여부에서의 유의한 차이를 보였고 음주문제를 더 많이 경험하였다. 2) 감각추구 성향에 있어 통계적으로 유의미할 정도로 스릴과 모험을 추구하는 것으로 나타났으며 경험추구척도(ES 척도)에서 알코올중독군이 소량음주자보다 유의하게 더 높은 점수를 보였는데 이는 알코올중독군이 비관습적이고 비동조적인 생활방식과 마음과 감각을 통해 새로운 경험을 추구하는 것으로 나타났다. 권태감과 무료감에 대한 취약성 척도(BS scale)에서는 통계적으로 유의미할 정도로 권태감 및 무료감에 더 많이 취약한 것으로 나타났으며 전체 감각추구 척도에서 통계적으로 유의미할 정도로 더 높은 것으로 나타났으나 탈억제 추구척도(DIS scale)에서는 차이를 보이지 않았다. 3) 두 집단 모두가 평소 음주량과 최대 음주량이 DIS scale과 유의한 상관관계를 보였고 권태감과 무료감에 대한 취약성 척도(BS scale)는 평균 음주량과 긍정적인 상관관계가 있었으며 경험 추구 척도는 평균 음주량 및 음주빈도와 긍정적인 상관관계가 있었다. 4) 탈억제 추구 성향을 포함한 감각추구 성향이 개인의 음주행동과 관련된 중요한 변인이라는 점을 밝힘으로써 앞으로 알코올중독 및 일반 성인의 음주행동을 이해하고 예방하며 치료하는데 많은 시사점을 주고 있다고 하겠다. Objects : To investigate the sensation seeking tendency of alcohol dependency, the authors have examined 45 alcoholics, and 45 nonalcoholic persons as a normal control group with demographic questions, sensation seeking and questionnaire on alcohol related problems. Method : In sampling, they confined the subjects to same age, sex and education in the alcoholics and normal control group. That was to remove the possibility that the above three variations could affect the results. Result : 1) The alcoholics showed a higher frequency of drinking, average and maximum volume of alcohol than normal control group. And there was a significant difference of legal punishment as well as the high incidence of family members with alcoholic problem. 2) In sensation seeking tendency, the alcoholics showed significant scores for thrill and adventures. BS, ES & Total scales were in significant tendency in the alcoholics compared with normal drinking groups. There was no significant correlation with DIS scale among groups. 3) Both of the two groups showed significant correlation with DIS scale in average and maximum volume of drinking. The tendency of boredom and weariness was positively correlated with average volume of drinking and so was the tendency of experience seeking with average volume and frequency of drinking. Conclusion : It is suggested that is desirable for the deal with the tendency of boredom and weariness and to develop tendency to seek new sensational experiences through unusual and unconventional life style and mental attitudes using other methods than alcohol. and all of the three groups seem to drink in order to avoid the social restraints.

      • KCI등재

        나이로 구분한 주정중독 1군과 2군의 감각추구 성향의 차이

        이병회(Byoung-Hai Lee):곽재봉(Jae-Bong Kwag):조용래(Yong-Rae Cho),김상훈(Sang-Hoon Kim):안주홍(Ju-Hong An) 한국중독정신의학회 2002 중독정신의학 Vol.6 No.2

        To investigate differences in sensation seeking tendency of Type I and Type II alcohol dependence, authors divided the people with alcohol dependence into two groups by onset age. We have examined 72 person of Type I alcoholics and 37 person of Type II alcohol dependence with demographic questions, sensation seeking questions on alcohol related problems. The results was as follows:1) There are no differences in average and maximum alcohol consumption volume, hospitalization count, legal problem, education level, family history of two groups. 2) Type II alcohol dependence showed high scores in Experience Seeking scale (ES scale) and Boredom Susceptibility scale (BS scale) and total score of 4 Sensation Seeking subscale. But, TAS scale and DIS scale showed no differences in two groups. 3) This results mean that early onset alcohol dependence pursuit new experience and is susceptible to boredom than late onset.

      • SCIEKCI등재
      • 두부외상후 우울기분을 보이는 환자의 특성에 관한 연구

        강호성,이병회,김상훈 조선대학교 부설 의학연구소 1998 The Medical Journal of Chosun University Vol.23 No.2

        Objective : This study was undertaken to identify the clinical and pathoanatomical correlates of depressed mood in patients with closed head injuries. Method : A consecutive series of 66 patients were examined by means of a semistructured psychiatric interview. The Hamilton Depression Rating Scale as well as scales measuring impairment in activities of daily living, intellectual functioning, and social functioning were administered. The patients' CT scans were also examined. Patients fulfilling criteria for depressed symptoms in PSE and DSM-Ⅳ were divided 2 groups based on the presence of depressed mood and compared to patients without depressed mood for background characteristics, impairment variables, and lesion characteristics. Results : There were 19 patients (28.8%) with depressed mood. The presence of left dorsolateral frontal lesion and/or left basal ganglia lesions and, to a lesser extent, parietal lesions was associated with increased probability of developing depressed mood. Conclusions : Depressed mood occures in about one-quarter of patients after traumatic brain injury. The findings suggest that the common symptom of post-brain injury depressed mood appears to be provoked by injury to certain critical brain lesions.

      • KCI등재

        백화옥수수 잎절편을 이용한 안토시아닌 생합성 조절제 탐색용 신규 검정법 확립

        김진석,이병회,이정애,오광훈,조광연,Kim, Jin-Seog,Lee, Byung-Hoi,Lee, Jung-Ae,Oh, Kwang-Hoon,Cho, Kwang-Yun 한국식물생명공학회 2003 식물생명공학회지 Vol.30 No.2

        This study was carried out to establish a novel bioassay system for screening of compounds affecting aromatic amino acid or anthocyanin biosynthesis through investigating a degree of sucrose-induced anthocyanin formation such as size of plant material, buffer conditions, light intensity and irradiated duration, incubation temp., etc were determined and standard procedure (suitable experimental condition) was set up as follows. The second leaf blade of white corn seeding induced by fluridone treatment were segmented into a size of 5${\times}$5 min. The segments were floated on the solution of 1% sucrose in 1.0mM MES buffer (pH6.0∼6.5) and incubated at 26$^{\circ}C$ for 2days under the continuous light condition(70∼100$\mu$mol m$^{-2}$ s$^{-1}$ ). Anthocyanin in the purpled tissues was extracted with methanol containing 1% HCl and the optical density of the clear supematants was determined at 528mm. Influences of some chemicals were tested using this system. Glyphosate, 5-enolpyruvylshikimate 3-phosphate synthase inhibitor, showed most sensitive response with I$_{50}$ value at 3.3$\mu$M. Dicyclohexylcarbodiimide(DCCD) and parachloromercuribenzenesulfonic acid(PCMBS) had a relatively strong ingibition with I50 value at 7.1$\mu$M and 10.2$\mu$M, respectively. These results show that sucrose-induced anthocyanin formation in white com leaf segment provide a very simple and rapid system for searching new compounds affecting aromatic amino acid or anteocyanin biosynthesis by screening at less than 10$\mu$M.

      • KCI등재

        Superoxide Dismutase와 Ascorbate Peroxidase가 엽록체내로 동시에 과대발현된 형질전환 담배의 제초제들에 대한 항산화 반응

        김진석,이병회,권석윤,김윤희,김소희,조광연,Kim Jin-Seog,Lee Byung-Hoi,Kwon Suk-Yoon,Kim Yun-Hee,Kim So-Hee,Cho Kwang-Yun 한국식물생명공학회 2005 식물생명공학회지 Vol.32 No.2

        Superoxide dismutase와 ascorbate peroxidase가 동시에 과대발현된 담배(CA)를 가지고 여러 제초제들에 대한 항산화 반응을 조사하였다. 온실조건 실험에서, CA 담배는 PSI 저해제로 알려진 paraquat처리에 대해서 내성이 인정되었고 그 정도는 40% 내외였다. PS II 저해제 (bromoxynil, diuron, bromacil), 엽록소 생합성 저해제 (oxyfluorfen), 카로티노이드 생합성 저해제 (fluridone)와 EPSP synthase 저해제 (glyphosate) 처리에서는 CA와 wild type간의 반응차이가 관찰되지 않았다. Paraquat와 diuron을 이용한 약광 조건의 실험에서도 온실조건의 실험결과와 유사한 정도로 paraquat처리에 대해서만 내성을 나타내었다. 온실조건에서의 엽위별 반응의 경우, 6 - 9 엽기 식물체에 paraquat를 처리하였을 때, 약제처리 당시 위로부터 3 - 4번째 전개되고 있었던 잎이 상대적으로 내성 정도가 높게 나타났다. 한편 paraquat 처리 시에 여러 농도의 ascorbic acid를 혼합할 경우, CA와 wild type 모두에서 비슷한 정도로 paraquat 활성을 경감시켰다. 결론적으로, CuZnSOD/APX의 과대발현은 photosystem I 에서 발생되는 산화스트레스에 대해서만 주로 작용하며, 다른 제초제들에 의해 발생되는 산화적 스트레스에 대해서는 소거 능력이 부족한 것으로 판단되었다. Antioxidative responses of transgenic tobacco plants expressing both superoxide dismutase (SOD) and ascorbate peroxidase (APX) in chloroplasts was investigated with several herbicides. In greenhouse test, tolerance of SOD/APX-overexpressed tobacco (CA) to photosystem (PS) I inhibitor paraquat was increased by about 40%. However, any response differences between CA and wild type (WT) tobacco was not observed in a treatment with PS II inhibitors (bromoxynil, diuron and bromacil), chlorophyll biosynthesis inhibitor(oxyfluorfen), carotenoid biosynthesis inhibitor (fluridone) and 5-enolpyruvylshikimate-3-phosphate (EPSP) synthase inhibitor (glyphosate). This tendency was also similar in the growth chamber test of low light intensity, using paraquat and diuron. That is, increased antioxidant activity of CA was shown only in paraquat treatment. When paraquat was foliar-treated to 6 to 9-leaf stage plant, the third to fourth placed leaf from shoot tip showed relatively higher antioxidant activity. Ascorbate supplemented to paraquat solution alleviated the phytotoxicity with a similar range in both CA and WT. In conclusion, CA specifically responded to oxidative stress induced by paraquat among tested herbicides in a whole plant assay.

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