Solitary Fibrous Tumor in Buccal Cheek Mucosa

윤청민,조정민,임광렬,김석권,김수진,이근철 대한두개안면성형외과학회 2017 Archives of Craniofacial Surgery Vol.18 No.3

A solitary fibrous tumor is a relatively uncommon neoplasm that usually occurs in the pleura but occurs extremely rarely in the oral cavity. Reported herein is a rare case of a solitary fibrous tumor in the buccal cheek mucosa. A 50-year-old man visited the authors’ hospital due to a buccal cheek mass whose size had increased. Excisional biopsy was done under local anesthesia. After the excisional biopsy, the patient was diagnosed to have a solitary fibrous tumor. In immunohistochemistry, the patient’s solitary fibrous tumor was characterized by the expression of CD34 and CD99 on the neoplastic cells, and negativity for Bcl-2 and S-100. No recurrence or complication occurred for a period of 5 years. The growth of a primary solitary fibrous tumor in the buccal cheek mucosa is extremely rare and has been rarely reported in the South Korean medical literature. A solitary fibrous tumor must be distinguished from other spindle cell tumors. Presented herein is a case of primary solitary fibrous tumor in the buccal cheek mucosa. The relevant literature is briefly reviewed.

Follicular Occlusion Triad: A Case Report

윤청민,Kwak Jung-Ha,한송희,최지안 대한창상학회 2021 Journal of Wound Management and Research Vol.17 No.2

Follicular occlusion triad (FOT) is a complex chronic inflammatory skin disease comprising hidradenitis suppurativa (HS), acne conglobata (AC), and dissecting cellulitis of the scalp (DCS; Hoffman’s disease or perifolliculitis capitis abscedens et suffodiens). While pathological mechanisms are responsible for common skin manifestations, the exact underlying causes of follicular occlusion have not yet been clearly identified. Therefore, the diagnosis and treatment of FOT remain challenging. A 31-year-old man on conservative treatment for previously diagnosed HS and AC presented to our clinic with multiple masses on his posterior neck and face. Excisional biopsy of the masses revealed epidermal cysts. Four months after the surgery, he presented with a painful palpable mass around the occipital region of the scalp with characteristic skin manifestations such as cicatricial alopecia and comedones and was diagnosed with DCS. Incision and drainage of the lesion were performed, and histopathology revealed pathological findings of follicular occlusion. The patient was diagnosed with FOT. Following the procedure, the patient has been on regular follow-up and is on oral isotretinoin; there have been no complications for the last 6 months.

Usefulness of Kaloderm® in Finger Tip Necrosis : A Case Report

윤청민,이승철,최지안 고신대학교(의대) 고신대학교 의과대학 학술지 2021 고신대학교 의과대학 학술지 Vol.36 No.2

We experienced a case of crush injury of the hand for which we performed a flap surgery and treated the necrotic parts placement using cultured allogeneic keratinocytes (Kaloderm®) with good results. The patient was a 31-year-old woman whose left middle finger was caught in a door, causing a crush injury. Although primary repair was performed, a 2 × 2.5-cm-sized necrosis developed, and a V-Y advancement flap was performed after the removal of dead tissues. However, a 1 × 2-cm-sized partial necrosis occurred and was treated using Kaloderm®. After the use of Kaloderm®, the patient’s wound was healed, and no complications, except for mild pain, were observed for 1 year after the surgery. If a necrotic site appears after flap placement of fingertip, its treatment is difficult. If used well, Kaloderm®may be a good option for necrosis of the fingertips and other areas that are difficult to cure.

두개골 결손이 있는 가토에서 Polybone®, Tisseel®과 Eglandin®이 골형성에 미치는 영향

윤청민 ( Chung Min Yoon ),김명훈 ( Myung Hoon Kim ),김민수 ( Min Su Kim ),김석권 ( Seok Kwun Kim ),김수진 ( Su Jin Kim ),이근철 ( Keun Cheol Lee ) 한국조직공학·재생의학회 2013 조직공학과 재생의학 Vol.10 No.2s

In plastic and reconstructive surgery, reconstruction of bone defect is commonly required in congenital anomaly or trauma. Autogenous bone graft is the most ideal material to reconstruct bone defect. Using the autogenous bone graft, however, is limited due to donor site morbidity and limitation of harvesting. β-tricalcium phosphate (β-TCP) is a homogenous high-purity chemical synthetic material with osteoconductivity. Fibrin forms the environment for fibroblast proliferation and accelerates wound healing. And Lipo-PGE1 promotes vasodilation and prevents platelet aggregation, and induces neovascularization. Thirty-two rabbits were divided 8 groups and 4 bone defects were made on each rabbit`s cranial bone. Bone defects were divided into four groups: control group, β-TCP group, fibrin sealant group, and β-TCP with fibrin sealant group. Lipo-PGE1 was intravenously injected to 16 rabbits, while normal saline was intravenously injected to the others. Results were evaluated by gross, histomorphological and histomorphometrical analysis at 1 week, 2 weeks, 4 weeks, 12 weeks after implantation. Mean percentage of the new bone formation area of β-TCP with fibrin sealant group was statistically significantly higher than that of the other groups. Although there was no statistical significance, mean percentage of the new bone formation area of applying Lipo-PGE1 group was higher than that of not applying Lipo-PGE1 group. We could verify the possibility of β-TCP with fibrin sealant being helpful in new bone formation. And we suggested the possibility of Lipo-PGE1 being helpful in new bone formation.

ALSAⓇ Gel Filler의 임상적 이용과 문제점

김석권,윤청민,이근철,박수성 대한미용성형외과학회 2011 Archives of Aesthetic Plastic Surgery Vol.17 No.3

As increasing demands for facial soft tissue augmentation by injection or minimal invasive procedures,filler injection has become a popular and proper method for patients’ demands. Autologous substance filler is safe and has no side effects, proceeded with the patient’s own blood plasma. From December 2009 to March 2010, subjects were total of 52 patients. Chief complaints of wrinkle on facial parts were extensive. Most patients received multiple injections on several facial parts. Blood samples taken from the patients were put in a centrifuge to separate plasma. Seprerated plasma was heated in 100 with ALSA (Alamouti and Sattler) system. ALSA gel filler was injected in the patients’ wrinkles and depressed areas. A week after the ALSA gel filler injection, most of them were satisfied. A month later, satisfaction was relatively high. But after 3 months, inquiry results changed, the number of unsatisfied patients increased. Because of absorption of injected ALSA gel filler. ALSA had less side effects than other fillers. ALSA could be used continuously, because its component was patient’s own blood plasma. However, compare to other fillers, duration was relatively short. More research needs to be performed to increase the duration period and supplement the shortcomings. (Archives of Aesthetic Plastic Surgery 17: 159, 2011)

Correlation between the time elapsed after liposuction and the risk of fat embolism: An animal model

임광열,조정민,윤청민,이근철,이상윤,주미하 대한성형외과학회 2018 Archives of Plastic Surgery Vol.45 No.1

Background Liposuction has become one of the most frequently performed procedures in the field of aesthetic surgery. Fat embolism syndrome after liposuction can easily be overlooked or underestimated; however, occasionally, fulminating fat embolism syndrome can develop and lead to a critical situation within 2–3 days after lipoplasty. Changes over time in the amount of circulating fat particles and the histology of major organs have not yet been studied. Methods This study was conducted using 18 male Sprague-Dawley rats aged 12 weeks and weighing 500–628 g (average, 562 g). Fifteen rats were used as the experimental group and 3 as the control group. Under general anesthesia, tumescent-technique liposuction was performed at the lateral flank areas and abdomen for 1 hour. Blood, lung, and brain tissue specimens were obtained at 1 hour, 1 day, and 2 days after the liposuction procedure. Results The average number of fat particles in the blood samples was 25,960/dL at 1 hour, 111,100/dL at 24 hours, and 21,780/dL at 48 hours. The differences between study groups were statistically significant. Both intravascular and extravascular fat particles with inflammation were seen in all 15 rats, as were inflammatory cell infiltration, hemorrhage, and consolidation with shrinkage of the lung alveoli. Conclusions These results imply that there is a strong possibility of fat embolism syndrome after liposuction in real clinical practice, and the first 24–48 hours after the operation were found to be the most important period for preventing pulmonary embolism and progression to fulminating fat embolism syndrome.

조상에 발생한 편평상피세포암: 증례 보고

최지안,곽정하,최정환,임광열,김대철,윤청민 대한수부외과학회 2020 대한수부외과학회지 Vol.25 No.1

Malignant tumors of the hand are rare. Squamous cell carcinoma (SCC) is the most common tumor that can develop at the nail bed. However, its prevalence is extremely rare. We report a male patient with SCC in the middle finger and provide a review of related literature. A 70-year-old male patient presented with subungal exudate of the right middle finger for 2 years. The lesion was treated by the patient himself without any relief. He visited the other hospital and underwent removal of the affected fingernail followed by histopathological examination. An extended excision was performed to remove the lesion located in close proximity with the distal phalanx along with a portion of the phalangeal soft tissues. The tumor shows malignant squamous sheets and nests with invasive growth pattern and pleomorphism. At the 6-month postoperative follow-up, neither symptom relapse nor other complications were observed. Various types of skin cancers, such as SCCs and malignant melanomas, can develop in the hand. However, their incidence is extremely rare. In particular, subungal lesions, which may be mistaken as fungal nail infections, require histopathological examination if they respond only slowly to treatment. 수부의 종양은 드문 것으로 알려져 있다. 조상의 가장 흔한 종양은 편평상피세포암이지만, 유병률 자체가 매우 드물다. 저자들은조갑진균증으로 오인된 중지의 편평상피세포암을 경험하여 문헌고찰과 함께 보고한다. 상기 환자는 70대 남자환자로, 약 2년 전부터우측 중지 조상에 삼출물이 발생하였으나, 조갑진균증으로 생각하고 자가치료하다 호전이 없어 타병원에서 조상 제거 후 조직검사를시행하였다. 병변부위가 원위지골과 인접하여 있어 광범위 절제술 후 원위지골 일부를 절제하였다. 병리조직검사에서 침습적 성장 양상및 다형성을 보이는 편평상피세포암이 관찰되었다. 수술 후 6개월간 경과관찰 결과 재발 및 합병증은 관찰되지 않았다. 수부의 피부암의경우 악성흑색종, 편평상피세포암등 다양한 암이 발생할 수 있지만, 유병률이 흔하지 않다. 조상의 경우 조갑진균증으로 오인하기 쉬워치유 속도가 느린 경우 반드시 조직검사가 필요할 것으로 사료된다.

Utility of Groin Flap in Penile Reconstruction

최지안,Kwak Jung-Ha,Lim Kwang-Ryeol,윤청민 대한창상학회 2020 Journal of Wound Management and Research Vol.16 No.3

Background: Reconstruction surgery for skin and soft tissue defects of the penis would ideally secure sufficient volume, be safe in procedure, and involve a simple surgical technique. Among the wide variety of techniques that have been employed, the groin flap-based technique is considered a relatively simple option for volumetric reconstruction. In this retrospective study, the authors report cases of penile reconstructive surgery using a groin flap.Methods: We performed a retrospective chart review of patients with penile defects treated in our department. Reconstructive surgeries were carried out using pedicled groin flaps. Charts were reviewed to investigate duration of the surgeries, recovery and follow-up periods, and bulkiness at one and 10 months after surgery. Patients were observed postoperatively for complications, urination, and erectile function.Results: Six patients hospitalized from March 2009 to September 2013 for penile defects underwent surgery in our department. All patients recovered without any flap loss. The most common complication after surgery was wound dehiscence. Circumferences of penile shafts were measured at 1 and 10 months after surgery, and penile bulkiness at rest were found to be maintained at >86%. There were no patients with contracture, and in all patients, urination and erectile functions were satisfactory.Conclusion: Reconstructing penile defects using groin flaps was found to be favorable in terms of volumetric reconstruction and postoperative patient satisfaction. Furthermore, the surgery and recovery periods are short, and rates of complication and donor site morbidity are also low.

전두-안와 구역에 발생한 섬유성 이형성증의 근치적 절제술 및 자가두개골 이식을 이용한 재건을 통한 치료: 증례보고

최지안(Ji-An Choi),곽정하(Jung-Ha Kwak),윤청민(Chung-Min Yoon) 대한두경부종양학회 2021 대한두경부 종양학회지 Vol.37 No.1

Fibrous dysplasia is a bone condition characterized by the replacement of normal bone tissue and the medullary cavity by abnormal fibrous tissues. Craniofacial fibrous dysplasia causes facial asymmetry compromising the aesthetics as well as vision and hearing. A 21-year-old male visited the clinic due to vertical orbital dystopia and exophthalmos that had developed over the previous 2 months. The patient was diagnosed with a fibrous dysplasia of the frontal, ethmoid bones and superior orbital wall. By a bicoronal incision on the scalp, the radical resection of the lesions was done. After harvesting the remaining frontal bone, we did the autogenous reconstruction using split calvarial bone graft. Postoperatively, the vertical orbital dystopia and exophthalmos significantly improved. The patient is satisfied with the surgical outcomes and has not reported any recurrence.

Treatment of Prosthetic Joint Infection and Reconstruction of a Massive Shoulder Defect after Reverse Total Shoulder Replacement

Choi Ji-An,Kwak Jung-Ha,Lim Kwang-Ryeol,윤청민 대한창상학회 2020 Journal of Wound Management and Research Vol.16 No.2

Prosthetic joint infection is a rare but serious complication of total shoulder replacement. After infection control, shoulder reconstruction is also required to repair the shoulder defect. The shoulder is a complex structure consisting of mechanical soft tissue and the joint, making reconstruction challenging. A 78-year-old female patient was diagnosed of wound necrosis and exposed prosthesis due to prosthetic joint infection after reverse total shoulder replacement. The infection was controlled with appropriate antibiotic treatment, and the necrotic tissue was removed by radical debridement. To reduce the size of the massive shoulder defect and minimize exposure of the prosthesis, negativepressure wound therapy (NPWT) was administered for 8 weeks and shoulder reconstruction was performed using a pedicled latissimus dorsi (LD) flap and split-thickness skin graft. The patient recovered without any complications, and no reinfection of the surgical site or other complications were observed during follow-up visits. This report demonstrates that antibiotic treatment, radical debridement of necrotic tissue, NPWT, and shoulder reconstruction using a pedicled LD flap can be an effective method of treatment for prosthetic joint infection with exposed prosthesis, tissue necrosis, and massive shoulder defect.