급속 진행성 사구체신염으로 시작된 현미경적 다발성 동맥염(Microscopic Polyangiitis) 환자의 7년간의 장기 추적관찰 1례

오진원,김병길,이재승,정현주,Oh, Jin-Won,Kim, Pyung-Kil,Lee, Jae-Seung,Jeong, Hyeon-Joo 대한소아신장학회 2008 Childhood kidney diseases Vol.12 No.1

현미경적 다발성 동맥염은 폐출혈과 급속 진행성 사구체심염을 특징으로 하는 전신성 혈관염의 일종으로 소아에서는 매우 드문 질환이다. 저자들은 폐출혈과 급성 신부전을 동반한 7세 여아에서 신장조직검사와 p-ANCA 검사로 현미경적 다발성 동백염으로 진단 후 5년 뒤 2차 신장조직검사와 경구 ACE inhibitor, angiotensin II receptor blocker와 저용량의 cyclophosphamide를 투여 받은 환아를 7년간 추적관찰하였다. 발병당시에는 BUN 117 mg/dL, Cr 2.3 mg/dL이었으나, 퇴원시 BUN 20.8 mg/dL, Cr 1.6 mg/dL이었고, 최근 검사에서는 BUN 51.7 mg/dL, Cr 3.2 mg/dL으로 만성 신병증 소견을 보이고 있으며, 외래 추적 관찰 지속 중에 있다. 이에 문헌 고찰과 함께 증례 보고하는 바이다. Microscopic polyangiitis(MPA) is a systemic necrotizing vasculitis that involves many organ systems including the skin, joint, kidneys, and lungs. In spite of early diagnosis and intensive care, the five-year actuarial patient and kidney survival rates are 65% and 55%. We experienced a case in 7-year-old girl of microscopic polyangiitis presenting with rapidly progressive glomerulonephritis which was confirmed by renal biopsy and positive serum perinuclear antineutrophil cytoplasmic autoantibodies(p-ANCA). The diagnosis of patients first renal biopsy was MPA, p-ANCA-associated crescentic glomerulonephritis. The patients second renal biopsy was done 5 years 6 months later since first renal biopsy, and pathologic diagnosis was chronic sclerosing glomerulonephritis, advanced, due to MPA. We began methylprednisolone pulse therapy, combined with a low dose of cyclophosphamide and plasmapheresis therapy. ACE inhibitor, angiotensin II receptor blocker, and cyclophosphamide were used until now and the patients current age is 14 years old. On admission, the patients laboratory findings showed BUN 117 mg/dL and Cr 2.3 mg/dL, while on the hospital day BUN and Cr values fell to 20.8 mg/dL and 1.6 mg/dL. But renal function was progressed to chronic failure with latest laboratory data BUN 51.7 mg/dL and Cr 3.2 mg/dL. ACE inhibitor, angiotensin II receptor blocker and small dose of immunosuppressant with close observation is the key to maintain the patient survival.

출판저널칼럼

오진원,O, Jin-Won 대한출판문화협회 2002 출판저널 Vol.323 No.-

〈똑똑똑, 평화 있어요?〉평화라는 것이 가능한가?

오진원 우리교육 2012 우리교육 Vol.250 No.-

분자동역학을 이용한 다공성 물질 건조공정 멀티스케일 시뮬레이션(1부 : 균질화법 해석)

오진원,백성민,금영탁 한국결정성장학회 2004 한국결정성장학회지 Vol.14 No.3

When porous materials are dried, the particles flocculate into fish-net structure in gel phase. In order to exactly analyze the stress distribution of porous materials during drying process, the elastic tensor of microscopic gel structures has to be predicted considering pore shapes as well as porosities of porous materials. The elastic characteristics of porous materials associated with porosities were predicted analyzing microscopic gel structures with circular and cross pores via homogenization method and the drying processes of the electric porous ceramic insulator were simulated using finite element method (FEM). Comparing analysis results between consideration and negligence of pores, the deformed shape and distributions of temperature and moisture were similar but the residual stress was significantly different. 다공성 물질이 건조될 때 입자는 겔 상태의 그물망 구조를 갖는다. 따라서 건조공정 중 발생하는 잔류응력을 정확하게 해석하기 위해서는 공극률과 공극형상에 따른 물성을 알아야 한다. 본 연구에서는 균질화법으로 원형과 십자형의 공극을 갖는 미시적인 겔구조로부터 공극률에 따른 재료의 탄성특성을 예측하고. 다공성 세라믹 애자의 건조공정을 유한요소 해석하였다. 해석 결과, 변형 형상과 온도, 습도 분포는 공극을 고려하지 않은 해석과 유사하지만 잔류응력 값은 큰 차이가 있음을 알 수 있었다.

오민욱의 다큐멘터리 <해협>에 나타난 역사 기술 연구

오진원,김이석 한국디지털영상학회 2022 디지털영상학술지 Vol.19 No.1

This article deals with the history description that appeared in director Oh Min-wook’s feature documentary film Letters to Buriram(2019). This film is an experimental documentary about the memory of war, a common experience shared by various East Asian cities. History is a key keyword that penetrates all of Oh Min-wook’s works. By the way, Oh Min-wook’s films are different from ordinary historical documentaries. This is because he views history from the perspective of "now-here" rather than objectively revealing the historical truth. In Letters to Buriram, Oh Min-wook captures the scars of war and the anxiety and sadness that exist in people’s hearts in various cities. Letters to Buriram takes the form of a letter from a woman living in Taiwan to her mother living in Thailand. This film differs from his previous works in that it reveals the existence of human beings in the foreground. Letters to Buriram shows memorial ceremonies in various asian countries. In addition, the film itself is playing a role in calling out the existence of the war victims and replacing their gaze. However, it itself plays a role in evoking the existence of the war victims. As a result, Letters to Buriram became a kind of ritual. Influenced by Structuralist films, Oh Min-wook’s films reveal meaning through the structure of formal elements rather than directly speaking the theme. Letters to Buriram also reflects on history through the juxtaposition and overlap of images and sound. In this film, the series of a stacked structure with multiple images and sounds overlapping provides the possibility of comprehensively and simultaneously grasping a situation.

쿠엔틴 타란티노 영화의 인물 분석 : <장고: 분노의 추적자>와 <헤이트풀 8>을 중심으로

오진원,김이석 한국디지털영상학회 2019 디지털영상학술지 Vol.16 No.2

This article is a study on the characters of two western films directed by American film director Quentin Tarantino, Django Unchained and Hateful Eight. Tarantino reinterprets in these films the old convention of Western movie. The leading roles of Django Unchained and Hateful Eight are both black. By the Western movie has contributed to build and strengthen American identity from the perspective of a white pioneer. Tarantino breaks the old convention of Western movie through Django Unchained and Hateful Eight. in which a black gunman appears as the main character. Tarantino's films are pluralistic and post-central; this is also revealed through the characters. The supporting roles in Django Unchained and Hateful Eight disintegrate the unified world built around the protagonist, socialize the conventional moral code, and make various narrative variations possible. Django Unchained and Hateful Eight are not just films that have simply changed the color of the protagonist’s skin; these two films reconstruct American history from the black people’s perspective. This historical and universality is a specificity that is hard to find in Tarantino's previous works. The ‘rewrite history’, which is sustainedly found from the director's sixth film Inglourious Basterds to the ninth film, One Upon a Time in Hollywood, provides a clue to Tarantino’s world.

현미경적 다발성 동맥염(Microscopic Polyangiitis) 환자의 7년간의 장기 추적관찰 1례

오진원 ( Jin Won Oh ),김병길 ( Pyung Kil Kim ),이재승 ( Jae Seung Lee ),정현주 ( Hyeon Joo Jeong ) 대한신장학회 2008 춘계학술대회 초록집 Vol.28 No.1

만성 두통 환아의 진단적 접근에 있어 어지럼증의 임상적 의의에 대한 연구

오진원(Jin Won Oh),이효상(Hyo Sang Lee),유황재(Hwang Jae Yoo) 대한소아신경학회 2008 대한소아신경학회지 Vol.16 No.2

목 적 : 소아에서 두통은 흔히 접하는 신경학적 증상으로 만성 두통을 보인 소아에서는 다른 질환과의 감별이 필요하다. 이에 저자들은 만성 두통을 가진 소아에서 진단적 접근 시 어지럼증을 동반하는 경우 어떤 질환을 염두에 두어 어떤 방향으로 검사를 진행해야 하며, 어떤 임상적 의의가 있는지를 알아보고자 하였다. 방 법 : 두통을 주소로 원인규명을 위해 입원을 하였거나 외래를 방문하여 검사를 받았던 환아들을 대상으로 하였다. 2004년 1월부터 2006년 7월까지의 환아들을 선별하였으며, 이들 중에 혈액검사, 소변검사, 뇌영상검사, 뇌파검사 등을 통해 원인질환을 조사할 수 있었던 총 86명이 선택되었다. 이들을 어지럼증을 동반한 군(Group A)과 어지럼증을 동반하지 않은 군(Group B)으로 나누어 연령, 성별, 두통의 임상양상, 두통의 원인에 대하여 조사하였다. 결 과 : 86명의 대상 환자 중 어지럼증을 동반한 경우(Group A)가 38명, 어지럼증을 동반하지 않은 경우(Group B)가 48명이었다. 남녀 비는 Group A는 1:1.7, Group B는 1:0.85로 Group A가 여아에서 높은 빈도를 보였으며, 연령은 Group A는 10세 이상인 경우가 73.7%로 대부분을 차지하였고, Group B는 7세 이하인 경우가 56.3%로 많은 부분을 차지하여 통계학적 유의성을 보였다. 두통의 발생시기에 있어서는 Group A는 주로 오전에 발생하였고, Group B는 주로 오후에 발생하였으며, 두통의 지속기간은 90분이상인 경우가 Group A의 50.0%에 비해 Group B는 87.5%로서 통계학적 유의성을 보였다. 두통의 발생빈도는 Group A는 대부분(92.1%)에서 주 4회 이상의 빈도를 보였으나 Group B는 주 4회 이상인 경우는 58.3%로서 Group A가 유의 있게 높은 빈도를 보였다. 동반증상으로는 Group A는 오심(47.3%), 구토(25.4%), 시력장애(12.7%) 등이었고, Group B는 시력장애(45.5%), 수명(14.8%), 구토(13.6%) 등의 순이었다. 두통의 원인으로는 Group A는 편두통(31.6%), 기립성 저혈압(15.8%), 체위성 기립성 빈맥 증후군(13.2%), 양성 발작성 두위 현훈증(10.5%) 등이었으며, Group B는 부비동염(50.0%), 편두통(31.3%), 합병성 편두통(8.3%) 등이었다. 결 론 : 만성 두통을 가진 소아에서 어지럼증을 동반한 두통을 가진 여아이면서 두통의 양상이 아침과 야간에 발생하는 특징을 보일 경우 전정기관의 이상과 체위불내성에 대한 검사를 먼저 시행하여 철저한 검사가 이루어져야 하며, 특정 질환이 의심된다 하더라도 편두통의 가능성을 두고 진단적 접근을 해야 할 것으로 사료된다. Purpose : Headache is a common neurologic symptom in children but chronic headache in them must be diagnosed in different ways. The aim of this study is to determine the algorithm of diagnostic approach for children with chronic headache and know the clinical significance of dizziness in evaluating those children. Methods : We recruited children with headache at Myongji Hospital from January 2004 to July 2006. The study was based on a retrospective review of their medical records and interviews with the children and their parents. We divided them into two groups : Group A headache with dizziness, Group B headache without dizziness. Results : The medical records of 86 children and adolescents with headache were reviewed. Age for group A ranged from 10 to 15 years(73.7%) and gender ratio was 1:1.7. Age for group B ranged mostly under 7 years(56.3%) and gender ratio was 1:0.85. Headache in group A frequently occurred predominantly in the morning(37.3%). The duration of the attack was over 90 min(87.5%) in group A and over 90 min(50.0%) in group B. Associated symptoms were mainly nausea(34.2%), vomiting(18.4%), blurred vision(12.7%) in group A. Over 90% of them had headache 4 times a week and so did dizziness. The final diagnoses in cases of group A were migraine(31.6%), orthostatic hypotension(15.8%), postural orthostatic tachycardia syndrome(13.2%), and benign paroxysmal positional vertigo(10.5%). While in group B diagnoses included sinusitis(50.0%), migraine(31.3%), and complications of migraine(8.3%). Conclusion : This study revealed high percentage of headache concurred with dizziness in children. The association of headache with dizziness is complex and maybe coincidental. If chronic headache with dizziness in girls occurs mainly in the morning, it maybe related to vestibular disorder and orthostatic instability. In conclusion, dizziness and other associated symptoms or clinical features should carefully be assessed in the diagnosis of headache.

사면붕괴 감지를 위한 전자파 측정 실험

오진원 ( Oh Jin-won ),임홍철 ( Rhim Hong-chul ),김종우 ( Kim Jong-woo ),한병원 ( Han Byung-won ),조윤범 ( Cho Yoon-bum ) 한국구조물진단유지관리공학회 2008 한국구조물진단유지관리공학회 학술발표대회 논문집 Vol.12 No.1

Abrupt landslide might cause the loss of properties, casualties, and the block of traffic on the road especially during rainy season in Korea. In this paper, a method using Ground Penetrating Radar (GPR) is proposed for the purpose of sending an early warning prior to a possible landslide. The GPR system measures the change of moisture content in the soil until it reaches a threshold of initiating the failure. A metal target is used as a reflector while the soil sample is moisturized at different levels of moisture content. Then, the dielectric constant of the soil is obtained based on the time of returned signal from the reflector. The results showed that this method is possible in predicting the change of moisture content within the soil sample and for the application to the landslide warning system.

GPR을 이용한 토질의 함수율 측정

오진원 ( Oh Jin-won ),임홍철 ( Rhim Hong-chul ),김종우 ( Kim Jong-woo ),한병원 ( Han Byung-won ),조윤범 ( Cho Yoon-bum ) 한국구조물진단유지관리공학회 2008 한국구조물진단유지관리공학회 학술발표대회 논문집 Vol.12 No.2

Materials including soil have dielectric properties, which represent the characteristics of the material in response to incoming electromagnetic waves. This information can be useful in determining the moisture content of soil for the purpose of predicting possible landslide. To develop a database for the dielectric properties of soil, a network analyzer has been used for laboratory measurements. To simulate field measurements, a soil tank has been made and the properties are measured using a ground penetrating radar (GPR). Results showed that GPR measurements are compatible with network analyzer values so that the GPR can be effectively used for the moisture level measurements in the field as a part of landslide prediction system.