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양미아(Mi-a Yang),경연정(Youn-Jeong Kyung),이혜경(Hae-Kyung Lee) 한국정보과학회 1990 한국정보과학회 학술발표논문집 Vol.17 No.2
정보화 사회라 일컬어지는 현대사회에서 실세계의 데이타화와 그 관리는 매우 중요한 문제로 부각되고 있다. 그러나 아직 주류를 이루는 화일중심의 데이타관리는 그 운용에 있어 많은 문제점들을 갖고있다. 그로인한 과정들 속에서 대두된 개념이 데이타베이스 관리시스템이다. 자료들에 대한 그 중요성이 더욱 확대되면서 이 DBMS에 대한 관심은 더욱 증가하고 있다. 이에 우리는 시스템에 대한 설계를 중심으로, 코볼(COBOL) 프로그램언어를 통한 화일처리와 데이타베이스 개념을 사용하여 시스템을 설계하고, 이들을 비교함으로써 데이타베이스 설계가 어느 정도 실효성이 있는지 알아보고자 한다.
양경아 ( Kyeong A Yang ),정락경 ( Rack Kyung Chung ),김동연 ( Dong Yeon Kim ),배민증 ( Min Jeong Bae ) 대한마취과학회 2008 Korean Journal of Anesthesiology Vol.55 No.6
Background: Pulse oximetry provides valuable data on the arterial oxygen saturation. Significant impairment in the arterial oxygen saturation can occur under vasoconstriction, hypothermia, and hypotension. This study compared the percutaneous oxygen saturation (SpO2) at the hand and the foot with the arterial oxygen saturation (SaO2) during spinal anesthesia. Methods: Twenty eight, ASA physical status 1 or 2, patients received a spinal block with 0.5% hyperbaric bupivacaine. Two pulse oximeter probes were applied to the index finger and second toe of the patients, and the SpO2 values were recorded before, 10, 20, and 30 minutes after the intrathecal injection. The SaO2 was measured before and 30 minutes after the intrathecal injection. Results: During spinal anesthesia, there were similar changes in the SpO2 value from the hand. However, there was a progressive decrease in SpO2 of the foot of 97.6 ± 2.8%, 97.3 ± 2.8%, and 97.2 ± 3.3% at 10, 20, and 30 minutes, respectively (P < 0.05 compared with the baseline). There were significant differences between the hand and foot SpO2 in 20 and 30 minutes (0.79 ± 1.55%, 0.93 ± 1.86%) after the intrathecal injection. The SaO2 value was similar before and 30 minutes after the intrathecal injection. Before spinal anesthesia, there were significant differences between the SaO2 (96.4 ± 2.6%) and SpO2 values of the hand (98.1 ± 2.6%) and the foot (98.3 ± 2.6%). Conclusions: During spinal anesthesia, it is appropriate to measure the SpO2 from the hand because it dose not change significantly. (Korean J Anesthesiol 2008; 55: 700~3)
구경이 ( Kyong-i Ku ),양경아 ( Kyung-a Yang ),김기헌 ( Ki-heon Kim ),정문영 ( Moon-young Chung ),최원혁 ( Won-hyuk Choi ),김원영 ( Won-young Kim ) 한국정보처리학회 2009 한국정보처리학회 학술대회논문집 Vol.16 No.2
본 논문에서는 데스크탑에서 실행되는 이동형 개인맞춤 SW 플랫폼 YouFree 의 개인용 위젯들을 사용자가 용도로 모아 배포하고 공유하는 시스템을 설계하고 구현하였다. 개발된 시스템에서는 사용자가 외부로부터 위젯 모음들을 다운받아 자신의 작업환경을 구축하거나, 사용자가 생성한 위젯 모음을 다른 사용자가 이용할 수 있도록 공유하는 기능을 제공한다. 따라서 개별적으로 위젯들을 설치하는 것보다 위젯 모음 공유 기능을 통해 더 빠르게 사용자는 자신의 작업환경을 구축할 수 있다.
혈액종양 ; 비편평세포, 비소세포폐암 환자에서 erlotinib, gefitinib 및 pemetrexed의 효과
윤라영 ( La Young Yoon ),양미연 ( Mi Yean Yang ),윤진아 ( Jin A Yun ),김현정 ( Hyun Jung Kim ),김한조 ( Han Jo Kim ),김경하 ( Kyung Ha Kim ),김세형 ( Se Hyung Kim ),이상철 ( Sang Cheol Lee ),김찬규 ( Chan Kyu Kim ),이남수 ( Nam Su 대한내과학회 2010 대한내과학회지 Vol.79 No.4
목적: 본 연구는 비소세포폐암의 2차 이상의 항암 화학 요법에서 EGFR TKIs와 pemetrexed의 임상적인 특징에 따른 치료 성적을 비교함으로써 구제치료의 선택에 도움을 주고자 하였다. 방법: 2002년 2월부터 2009년 8월까지 부천 순천향대학교 병원 혈액종양내과에서 비소세포폐암을 진단받은 환자들 중 편평상피암을 제외한 선암과 대세포암 환자들을 대상으로 하였으며 이들 중 gefitinib이나 erlotinib 및 pemetrexed로 치료받은 환자를 의무기록을 통해 후향적으로 조사하였다. 결과: 총 61명이 연구에 참여하였고 그 중 erlotinib군이 18명, gefitinib군은 18명, pemetrexed군은 25명이었으며 중앙관찰기간은 37개월(7-97개월)이었다. 세 군간에 반응율과 무진행 생존기간에는 의미있는 차이가 없었으며 EGFR TKIs 를 투여받은 환자들 중에서는 여성에서 보다 좋은 반응율은 보였고, erlotinib 을 투여받은 환자들 중 피부발진이 있었던 환자들과 Pemetrexed를 투여 받은 환자들 중 선암으로 진단된 경우에서 무진행 생존기간이 의미있게 길었다. 결론: EGFR TKIs 와 Pemetrexed 는 모두 비편평세포암, 비소세포암 환자에서 2차 이상의 치료로 사용하였을 때 비교적 효과적이었으며 부작용도 적은 것으로 나타났다. 향후 EGKR TKIs 및 pemetrexed군 치료 효과 및 치료 효과에 영향을 미치는 다양한 임상적 예후인자에 대한 보다 많은 대규모 전향적 비교 연구가 필요할 것이다. Background/Aims: This study compared the clinical benefits of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs) with pemetrexed to identify the clinical parameters that correlated with response. Methods: A retrospective chart review examined patients who were 1) treated with EGFR TKI or pemetrexed, 2) diagnosed with advanced non-squamous non-small-cell lung cancer, and 3) previously treated with platinum-based chemotherapy in Soonchunhyang Bucheon Hospital. Results: Sixty-one patients (18 erlotinib, 18 gefitinib, 25 pemetrexed) were investigated from February 2002 to August 2009. The median follow-up period was 37 months (7~97 months). Overall, their median age was 63 years, 41 patients were non-smokers, 57 patients had adenocarcinoma, and 55 patients were at stage IV. Twenty-one patients received the study drugs as second-line chemotherapy, and others as third-line or more. No significant differences in the overall response rate (erlotinib 33.3% vs. gefitinib 38.9% vs. pemetrexed 20.0%) and progression-free survival (erlotinib 1.9 months vs. gefitinib 3.0 months vs. pemetrexed 2.9 months) were found among the three groups. Female gender was related to a good response to EGFR TKIs (p=0.047). Skin rash in the erlotinib group (p=0.037) and adenocarcinoma in the pemetrexed group (p=0.02) were related to improved progression-free survival. Few side effects were reported. Conclusions: Both EGFR TKIs and pemetrexed therapy for non-squamous non-small-cell lung cancer were efficient and tolerable after the failure of first-line platinum-based chemotherapy. Further prospective studies are needed to validate the predictive role of the suggested clinical parameters in this study. (Korean J Med 79:394-403, 2010)
연구논문 : 뽕잎 항산화능 및 뽕잎가루 머핀의 품질특성
이혜연 ( Hye Yeon Lee ),정현아 ( Hyeon A Jung ),김동한 ( Dong Han Kim ),권후자 ( Hoo Ja Kwon ),이명희 ( Myung Hee Lee ),김안나 ( An Na Kim ),박찬성 ( Chan Sung Park ),양경미 ( Kyung Mi Yang ),배현주 ( Hyun Joo Bae ) 한국식품조리과학회(구 한국조리과학회) 2011 한국식품조리과학회지 Vol.27 No.4
The function of mulberry leaves and the quality of muffins including mulberry leaves were examined. The electron donating ability of both a water and ethanol extract was 40% for both at 100 ppm, 62 and 72% at 500 ppm, and 77 and 83% at 1,000 ppm respectively. These experiments showed good oxidized substance activity. The SOD-like ability of the water and ethanol extracts at 1,000, 500, and 300 ppm was 49% and 55%, 33% and 39%, and 28% and 33% respectively. These results show that the ethanol extract had higher SOD-like ability than that of the water extract. The nitrite scavenging abilities of 1,000 ppm of the mulberry leaf water extract and ethanol extract at pHs of 1.2 and 3.0 were 40.5 and 47%, and 20 and 22% respectively. The Hunter lightness value tended to be lower as the amount of added mulberry leaves increased compared to the contrast set, so the lightness level with a 7% addition was the lowest. The contrast set was the highest for redness and added mulberry leaves tended to decrease redness at 3% but tended to increase it again with additions >3%. The b-value (yellowness) showed a similar tendency as redness. Adding Mulberry leaves tended to decrease the contrast set to the lowest level, then values increased slowly to a peak at 5% added mulberry leaf and then decreased thereafter. Strength and hardness were less after increasing added mulberry leaf. Cohesiveness, springiness, gumminess and brittleness, decreased at up to 5% added mulberry leaves but the 7% addition showed the same level as the contrast set. The mulberry leaves muffins were less preferred to the contrast set in appearance and color. However, the mulberry leaf muffins were preferred to the contrast set in taste and flavor but the result was not significant. Overall the quality of the muffins with 3% added mulberry leaves was preferred over the 1% added mulberry leaf muffins.
김용남 ( Yong Nam Kim ),이향이 ( Hyang Ee Lee ),이상훈 ( Sang Hoon Lee ),이연아 ( Yeon A Lee ),우두현 ( Doo Hyun Woo ),황보영 ( Young Hwangbo ),조경삼 ( Kyung Sam Cho ),박용구 ( Yong Koo Park ),양형인 ( Hyung In Yang ) 대한류마티스학회 2005 대한류마티스학회지 Vol.12 No.3
Plasmacytomas are tumors composed of plasma cells of variable maturity, which are histologically identical to those seen in multiple myeloma. Ankylosing spondylitis is a chronic inflammatory disease, probably resulting from the interaction of a genetic predisposition involving HLA-B27 with an environmental event such as enteric bacterial infection. Multiple myeloma has been intermittently reported in patients with ankylosing spondylitis. It has been proposed that the protracted stimulation of immunocytes by inflammatory lesions on the mucosal surfaces of the gastrointestinal, respiratory tracts may be implicated in the pathogenesis of multiple myeloma in some patients. We observed a 23 year old male patient with a history of plasmacytoma who subsequently developed ankylosing spondylitis. He was diagnosed as plasmacytoma 4 years ago and took a radiation therapy. There was no previous report of ankylosing spondylitis following plasmacytoma. The relationship between two diseases is uncertain until now and further study should be needed.
김그림 ( Geu Rim Kim ),박지혜 ( Ji Hye Park ),양예은 ( Ye Eun Yang ),이경아 ( Kyung A Lee ) 대구가톨릭대학교 자연과학연구소 2014 자연과학연구논문집 Vol.12 No.1
The purpose of this study was to investigate preference for salty taste of University foodservice customer in the Gyeongsangbuk-do area. Data were collected from subjects, including 94 male and 213 female University students. This survey was conducted using self-boarding Questionnaires. By the stage of salt-related dietary behaviors, the ``Pre-contemplation stage`` comprised 39.1%, ``Contemplation stage`` 29.1%, ``Preparation stage`` 14.9% and`` Action stage`` 16.9%. Exactly 38.5% of all students showed ``salty`` for self-assessed preference of saltness, and 56.4% showed ``salty`` for assessed saltness of university foodservice operation. Male had higher self-assessed preference for salty taste more than female, overweight students had higher the score, and ``Pre-contemplation stage`` group had higher the score than other group.