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MDA기반 컴포넌트 설계정보 관리도구의 개발에 관한 연구
안용수 ( Yong-soo Ahn ),황상원 ( Sang-won Hwang ),남영광 ( Young-kwang Nam ),이병윤 ( Byeong-yun Lee ),권오천 ( Oh-cheon Kwon ) 한국정보처리학회 2011 한국정보처리학회 학술대회논문집 Vol.18 No.1
MDA(Model Driven Architecture)는 추상적인 모델 계층을 사용하기 때문에 다양한 플랫폼에 적용가능하고, 각 모델 계층과 코드 생성의 자동화를 통해 개발의 효율성을 극대화한다. 본 연구에서는 XML 형태로 저장된 설계정보를 분석하여 MDA 기반 컴포넌트 설계 정보를 관리하는 도구를 개발하였다. 이 도구는 UML로 작성된 설계모델를 XMI(XML Metadata Interchage) 형태로 저장하여 각종 설계도구에서 Java, C++과 같은 언어에 대한 실제 프로그램 골격코드가 자동으로 생성되도록 하였다. 역으로 골격코드를 기반으로 구현된 콤포넌트의 원시코드를 수집하여 다시 컴포넌트 설계모델 정보를 추출하는 기능을 구현하였고, 이를 다시 시각적 정보로 재구성 하였다. 이러한 기능들은 기존의 단방향적 개발 구조 방식에서 벗어나 이미 개발되거나 개발 중인 프로그램에 대한 분석 및 평가 등을 통해서 재사용성을 높여주는 순환적인 개발 구조 방식을 제공한다.
크론병 환자에서 임신 초기 Infliximab 투여 후 정상 분만한
장영우 ( Young Woo Jang ),박영숙 ( Young Sook Park ),김성환 ( Seong Hwan Kim ),조윤주 ( Yun Ju Jo ),조영관 ( Young Kwan Jo ),안상봉 ( Sang Bong Ahn ),서용수 ( Yong Soo Seo ),홍영옥 ( Young Ok Hong ) 대한소화기학회 2013 대한소화기학회지 Vol.61 No.1
Infliximab is a chimeric IgG1 monoclonal antibody to tumor necrosis factor (TNF)-α used in the treatment of steroid refractory or dependent Crohn`s disease (CD). Patients with active CD are more likely to experience stillbirth, preterm labor, or small for gestational aged babies. The safety of administering infliximab in pregnant patients is not well documented. A 25-year-old woman, who was diagnosed with small bowel CD three years ago, was admitted to our hospital due to the aggravation of abdominal pain. She had been treated with mesalazine, azathioprine and intermittent steroid for three years. After admission, she did not respond to steroid therapy, we decided to try infliximab. After the administration of infliximab, epigastric pain was relived and Crohn`s disease activity index score decreased significantly. However after the fourth infusion of infliximab, the patient became aware that she was ten gestational weeks old pregnancy state After then, infliximab was stopped and maintained by mesalazine. The patient gave birth to a healthy baby via normal vaginal delivery without the recurrence of CD. This case suggests that infliximab administration is safe during the early period of pregnancy. Thus, we report this case with a review of literature. (Korean J Gastroenterol 2013;61:37-41)
증례 : 호흡기 ; 내시경적 제거와 단기간 항생제 투여로 완치된 기관지 방선균증 2예
이은우 ( Eun Woo Lee ),안용수 ( Yong Soo Ahn ),황영준 ( Young Jun Hwang ),이민근 ( Min Geun Lee ),정홍명 ( Hong Myong Jung ),윤재성 ( Jae Sung Youn ),김우종 ( Won Jong Kim ) 대한내과학회 2010 대한내과학회지 Vol.79 No.5
이물질과 관련된 기관지내 방선균증은 기침, 가래, 호흡곤란, 반복되는 폐렴을 특징으로 하는 구인두 상재균인 Actinomyces israelii에 의한 감염으로 과거에는 초기 진단이 되지 않아 수술적인 치료 및 장기간의 항생제 치료를 필요로 하였다. 저자들은 기침, 혈담 등을 주소로 내원하여 이물질에 의한 기관지내 방선균증으로 진단된 2명의 환자를 경험하였다. 기관지 내시경을 통해 이물질이 비교적 잘 제거된 경우에는 고식적인 항생제 요법보다 더 짧은 기간의 항생제 치료만으로도 성공적인 치료를 하였기에 보고하는 바이다. Actinomycosis is an uncommon, chronic granulomatous, suppurative disease related to Actinomyces israelii, which is a natural inhabitant of the oropharyngeal cavity and the major human pathogen of actinomycosis. In the past, dramatic presentation of thoracic actinomycosis, in conjunction with prominent chest pain and cutaneous fistulas that discharge sulfur granules, has frequently been reported. However, more recent data indicate that chest wall or rib involvement is now much less common than was previously encountered. This could result in more favorable responses to short-term intravenous antibiotic therapy. Foreign-body-associated actinomycosis is a very rare type of thoracic actinomycosis. We report two cases of endobronchial actinomycosis associated with a foreign body. In both cases, the foreign body was successfully removed by bronchoscopy. Each patient was treated with antibiotics for about 70 days. The duration of antibiotic therapy was relatively short, as compared to conventional therapy. Nevertheless, there was no recurrence or complications over 1 year. (Korean J Med 79:563-568, 2010)
김도현 ( Do Hyun Kim ),정홍명 ( Hong Myong Jung ),황영준 ( Young Jun Hwang ),안용수 ( Yong Soo Ahn ),문장식 ( Jang Sik Mun ),명보현 ( Bo Hyun Myoung ),박혁 ( Hyeuk Park ),정은주 ( Eun Joo Jeong ),임윤미 ( Yun Mi Im ),오현민 ( Hyu 대한소화기학회 2010 대한소화기학회지 Vol.56 No.1
Background/Aims: Helicobacter pylori (H. pylori) transmission route is not yet clearly understood. Isolating H. pylori from stool, saliva, and vomitus is very difficult. However, H. pylori could be cultured from feces in the setting of rapid gastrointestinal tract transit. The aim of this study was to isolate H. pylori by culture and PCR in the rectum and terminal ileum during colonoscopy. Methods: Twenty subjects with positive UBT (urea breath test) were included. We performed polymerase chain reaction (PCR) test and culture of H. pylori with the rectal fluid and terminal ileal fluid during colonoscopy. Results: H. pylori was cultured with rectal fluid from 9 (45.0%) of 20 subjects and with ileal fluid from 11 (55.0%) of 20 subjects. H. pylori was a little more frequently cultured from the terminal ileal fluid than the rectal fluid without statistical significance (p>0.05). PCR test detected flaA (16/20, 80.0% and 17/20, 85.0%), 16S rRNA gene (16/20, 80.0% and 17/20, 85.0%), cagA (10/20, 50.0% and 12/20, 60.0%), and ureC (9/20, 45% and 11/20, 54.5%) from the rectal fluid and the terminal ileal fluid, respectively. The specificity and sensitivity of ureC were 100%. Conclusions: H. pylori could be cultured from the rectal fluid and terminal ileal fluid in the setting of rapid gastrointestinal tract transit. These results suggest of fecal-oral transmission of H. pylori. (Korean J Gastroenterol 2010;56:27-32)