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- 저자 : 송재천 ( Jae Chun Song ) (검색결과 6 건)
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송재천 ( Jae Chun Song ),김상겸 ( Sang Kyum Kim ),김익성 ( Eak Seong Kim ),정인수 ( In Su Jung ),송영구 ( Young Goo Song ),유정식 ( Jeong Sik Yu ),박효진 ( Hyo Jin Park ) 대한소화기학회 2008 대한소화기학회지 Vol.52 No.4
We experienced a rare case of colonic cryptococcosis in an apparently immunocompetent individual. A 27-year-old woman admitted our hospital for intermittent melena. Initial abdominal CT scan revealed a mass lesion obstructing most of the lumen in ascending colon. Colonoscopy showed huge ulcerofungating mass in proximal ascending colon. Colonoscopic biopsy was performed and pathologic diagnosis was made as colonic cryptococcosis with positive PAS stain. Laboratory test evaluating immune status and bone marrow examination was normal. The patient was treated with intravenous amphotericin B for four weeks and six months of oral fluconazole afterwards. Follow-up abdominal CT scan and colonoscopy were taken at four weeks and seven months after the beginning of treatment. On completion of intravenous amphotericin B treatment, the mass lesion was decreased in abdominal CT and colonoscopy. After seven months, abdominal CT and colonoscopy showed near-complete resolution of the colonic lesion so the treatment ended. Cryptococcosis in a healthy individual is a rare disease and there have been only several sporadic case reports on pulmonary or central nervous system involvement. Hence, we report a case of colonic cryptococcosis in an apparently immunocompetent individual. (Korean J Gastroenterol 2008;52:255-260)
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대장내시경 전 처치 약제 Solin(R) 투여 후 발생한 고인산혈증 및 급성신부전 1예
박종원 ( Jong Won Park ),송재천 ( Jae Chun Song ),임현철 ( Hyun Chul Lim ),강병승 ( Byeung Seung Kang ),배기선 ( Ki Sun Bae ),박효진 ( Hyo Jin Park ),하성규 ( Sung Kyu Ha ) 대한내과학회 2008 대한내과학회지 Vol.75 No.6
Solin(R) (Oral sodium phosphate)은 삼투성 하제로 기존에 사용되고 있던 PEG와 동등 이상의 효과와 환자 순응도를 보여 대장내시경 전처치로 임상에서 널리 쓰이고 있으나, 이에 동반하여 고인산혈증, 저칼슘혈증 등으로 대표되는 전해질 불균형과 급성 신부전을 유발할 수 있다. 저자들은 기저 신기능이 정상이며 전해질 불균형이 없었던 61세 여자환자에서 Solin(R) 복용 후에 고인산혈증과 급성 신부전이 발생하였기에 문헌고찰과 함께 보고하는 바이다. Solin(R) (oral sodium phosphate) is a commonly used osmotic laxative solution that has replaced polyethylene glycol in bowel preparation for colonoscopy as it has equal or greater efficacy and patient compliance. However, its use has been associated with several cases of acute renal failure and electrolyte imbalance, especially hyperphosphatemia and hypocalcemia. Those at higher risk of complications are patients who are older and have intestinal obstruction, inflammatory bowel disease, renal failure, or congestive heart failure. We report the case of a 61-year-old woman presenting with paresthesia in both hands after using Solin(R) for bowel preparation for colonoscopy. The patient had hypocalcemia and hyperphosphatemia combined with acute renal failure. She recovered from the renal failure and electrolyte imbalance with intravenous hydration and treatment with phosphate-binding agents. (Korean J Med 75:689-693, 2008)
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김은미,김세원,김상운,이경희,현명수,박원규,장재천,송선교,Kim, Eun-Mi,Kim, Se-Won,Kim, Sang-Woon,Lee, Kyung-Hee,Hyun, Myung-Soo,Park, Won-Kyu,Chang, Jae-Chun,Song, Sun-Kyo 대한위암학회 2006 대한위암학회지 Vol.6 No.4
목적: 간전이 위암환자들을 대상으로 치료 결과를 알아보고 생존 분석을 통해 예후를 확인하고자 하였다. 대상 및 방법: 1990년 3월부터 2006년 3월까지 영남대학교 영남의료원 내과 및 외과에 내원한 위암환자 중 간전이가 발견된 85예(동시성 62예, 이시성 23예)를 대상으로 후향적 연구를 시행하였다. 임상병리학적 인자와 위절제술, 간전이병소 절제술 및 항암화학요법 등 치료 관련 인자들에 대해 생존분석을 실시하였다. 결과: 간전이 위암환자들의 중앙생존기간은 11개월(동시성 11개월, 이시성 17개월)이었다. 동시성 간전이군의 경우 위절제율은 24.1%, 간전이병소 절제율은 16.1%였다. 간외 전이 동반율은 23.5%였고 생존기간에 차이가 있었다(P<0.05). 간전이 병소 절제 및 위절제군, 위절제군, 비절제군의 중앙생존기간은 각각 60개월 이상, 10개월 및 9개월이었다(Fig. 1, P<0.05). 이시성 간전이군의 경우 위암절제 후 무병생존기간의 중앙치는 8개월이었으며 초기병기와 간전이 빈도 사이에는 차이가 없었다. 동시성 간전이군에서는 단변량 분석 결과 간외 전이, 위절제술, 간전이 병소 절제술, 외과적 절제 형태 및 항암화학요법에 대한 반응이 유의하였고 다변량 분석 결과 간전이병소 절제술, 항암화학요법에 대한 반응 및 간외 전이가 독립적 예후인자였고, 이시성 간전이군에서는 간외 전이, 항암화학요법에 대한 반응 및 원발암 세포의 분화도가 유의하였고 간외 전이가 독립적 예후인자였다. 결론: 간전이 위암환자에서 예후는 간전이 병소의 절제, 원발 병소의 절제, 간외 전이 유무 및 항암화학요법에 대한 반응여부에 의해 결정되므로 치료에 있어 간외 전이가 없는 경우 보다 적극적인 절제 노력과 항암화학요법이 생존율 향상에 기여할 것으로 판단된다. Purpose: This study was conducted to evaluate the treatment outcomes and the prognosis for gastric cancer patients with hepatic metastasis. Materials and Methods: This retrospective study was based on the medical records of 85 gastric cancer patients with hepatic metastasis (62 synchronous and, 23 metachronous) who received chemotherapy with or without resectional therapy from March 1990 to March 2006. The survival rate was analyzed according to clinicopathologic factors and therapeutic factors, such as whether or not a gastrectomy, a hepatic resection, and/or chemotherapy had been performed. Results: The median survival of gastric cancer patients with hepatic metastasis was 11 months (synchronous: 11 months and metachronous: 17 months). The rates of gastrectomies and hepatic resections in the synchronous group were 24.1% and 16.1%, respectively A 23.5% prevalence of extra-hepatic metastasis was observed. The median survivals of patients who underwent a gastrectomy with a hepatic resection, a gastrectomy alone, and non-surgical treatment were 60, 18, and 9 months, respectively (P<0.05). The disease-free median survival of the metachronous group was 8 ($3{\sim}39$) months. There was no difference in initial pathologic stage and frequency of hepatic metastasis after the gastrectomy in the metachronous group. In the synchronous group, extra-hepatic metastasis, a gastrectomy as the operative procedure, a hepatic resection as the operative procedure and the response to chemotherapy were statistically significant in the univariate analysis, and a hepatic resection as the operative procedure, the response to chemotherapy, and extra-hepatic metastasis were independant prognostic factors identified by the multivariate analysis. In the metachronous group, extra-hepatic metastasis, the response to chemotherapy and differentiation were statistically significant in the univariate analysis, and extra-hepatic metastasis was an independent prognostic factor identified by the multivariate analysis. Conclusion: An aggressive surgical therapy and effective chemotherapy are necessary in the treatment of gastric cancer patients with hepatic metastasis. (J Korean Gastric Cancer Assoc 2006;6:237-243)
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Fe/SiO2 촉매상에서 Fischer - Tropsch 합성반응
이화영,유승호,송재천 한국화학공학회 1989 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.27 No.4
철담지촉매를 이용하여 Fischer-Tropsch 합성반응실험을 수행하였으며, 반응조건은 전압 1 atm, 온도 270℃이었다. 촉매의 활성은 10-20시간 후에 정상상태에 이르며 환원시간이 길수록, 환원온도가 높을수록 활성이 안정하였다. 또한 전혀 환원하지 않은 촉매도 활성을 나타내었다. 그러나 정상상태에서의 활성은 환원조건에 의해 크게 영향받지 않았다. 칼륨이 첨가된 촉매에서는 활성의 커다란 저하없이 올레핀 선택도가 향상되었으며 이산화탄소의 생성이 증가되었다. 공간속도 9460 hr^(-1), H₂/CO=2의 반응조건하에서 최대 53.6%의 올레핀 선택도를 보였다. The Fischer-Tropsch syntheses over silica-supported iron catalysts were carried out in an atmospheric reactor at 270℃. The catalytic activity extended to steady-state value after 10-20 hour reaction. The longer reduction period and the higher reduction temperature made the catalytic activity more stable, and even unreduced catalyst showed similiar activity. K-promoted catalysts showed higher olefin selectivity and increased CO₂ production rate with little decrease of activity. The maximum olefin selectivity of 53.5% was obtained at space velocity of 9600 h^(-1), H₂/CO=2.
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