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      • KCI등재
      • KCI등재

        Pattern of Lymph Node Metastasis Correlates with Tumor Location in Bladder Cancer

        박원규,김영식 대한비뇨의학회 2012 Investigative and Clinical Urology Vol.53 No.1

        Purpose: Resection of a large number of lymph nodes (LNs) increases survival in patients with LN-positive disease; however, morbidity also increases. Here, we investigated the correlation between tumor location and LN metastasis in bladder cancer. Materials and Methods: Thirty-six patients with pathological N1 or higher bladder cancer, who underwent radical cystectomy with extended lymphadenectomy, were reviewed retrospectively. The tumor location was classified as right, left, front, posterior, or whole bladder. The LN metastasis pattern was classified as right, left, or bilateral. The correlation between tumor location and LN metastasis was determined by chi-square test. Survival rates were compared by Kaplan-Meier analysis. Results: The numbers of patients with a tumor on the right (group 1), left (group 2), posterior (group 3), or whole (group 4) bladder were 16 (44.4%), 16 (44.4%), 2 (5.6%), and 2 (5.6%), respectively. In group 1, 14 patients (87.5%) had right-sided ipsilateral LNs, and 2 patients (12.5%) had left-sided contralateral LNs. In group 2, 4 patients (25%) had right-sided contralateral LNs, and 12 patients (75%) had left-sided ipsilateral LNs. In group 3, both patients (100%) had right-sided posterior LNs. In group 4, both patients (100%) had positive LNs on both sides. Tumor location and LN metastasis were significantly correlated (p<0.05). Moreover, the survival rate was significantly higher in patients with no LN metastasis than in patients with ipsilateral or contralateral LN-positive bladder cancer. Conclusions: The location of the bladder tumor and direction of metastatic spread were significantly correlated. Mandatory bilateral lymphadenectomy during radical cystectomy should be questioned. Purpose: Resection of a large number of lymph nodes (LNs) increases survival in patients with LN-positive disease; however, morbidity also increases. Here, we investigated the correlation between tumor location and LN metastasis in bladder cancer. Materials and Methods: Thirty-six patients with pathological N1 or higher bladder cancer, who underwent radical cystectomy with extended lymphadenectomy, were reviewed retrospectively. The tumor location was classified as right, left, front, posterior, or whole bladder. The LN metastasis pattern was classified as right, left, or bilateral. The correlation between tumor location and LN metastasis was determined by chi-square test. Survival rates were compared by Kaplan-Meier analysis. Results: The numbers of patients with a tumor on the right (group 1), left (group 2), posterior (group 3), or whole (group 4) bladder were 16 (44.4%), 16 (44.4%), 2 (5.6%), and 2 (5.6%), respectively. In group 1, 14 patients (87.5%) had right-sided ipsilateral LNs, and 2 patients (12.5%) had left-sided contralateral LNs. In group 2, 4 patients (25%) had right-sided contralateral LNs, and 12 patients (75%) had left-sided ipsilateral LNs. In group 3, both patients (100%) had right-sided posterior LNs. In group 4, both patients (100%) had positive LNs on both sides. Tumor location and LN metastasis were significantly correlated (p<0.05). Moreover, the survival rate was significantly higher in patients with no LN metastasis than in patients with ipsilateral or contralateral LN-positive bladder cancer. Conclusions: The location of the bladder tumor and direction of metastatic spread were significantly correlated. Mandatory bilateral lymphadenectomy during radical cystectomy should be questioned.

      • SCOPUSKCI등재

        Ester - Alcohol 계의 기액평형(1)

        박원규,배효광 한국화학공학회 1970 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.8 No.4

        Vapor-liquid equilibrium data for the systems, MeAc-MeOH, MeAc-EtOH, MeAc-n-PrOH and MeAc-n-BuOH, were measured under the atmospheric pressure. The mixture of ester-alcohol was distilled and recycled in a Smith-Bonner type apparatus for 2 hours or longer. Using the density-composition diagrams plotted previously, x-y data were found out for each experimental run and were discussed to be correct or not, by means of Herington's consistency test, Q function-composition and activity-composition relations. The constants of Prahl's equation were determined experimentally and were confirmed to be reasonable all over the range of composition. Therefore, authors suggest the smoothed data of vaporliquid equilibrium for the systems of methylacetate-alcohol.

      • KCI등재
      • SCIESCOPUSKCI등재
      • 나무나이테를 이용한 설악산 지역의 4월~8월 총강수량 복원

        박원규,서정욱,김요정,한수원 한국제4기학회 2001 제사기학회지 Vol.15 No.1

        설악산 백담산장 (해발고 400m) 지역에서 자라는 소나무를 이용하여 141년 (A.D. 1858∼1998)간의 나무나이테(연륜) 연대기를 작성하여 4월∼8월 총강수량을 복원하였다. 복원한 결과 1880∼1887년, 1893∼1901년, 1922∼1938년은 건조기로 나타났으며, 1906∼1918년은 습윤기로 나타났다. 장기간 변동으로 보았을 때, 19세기말과 20세기초는 20세기 후반기보다 건조하였다. 전기간에 걸친 가뭄주기는 4.14년과 3.16년으로 분석되어 장주기보다 단주기 변화가 우세하였다. April∼August precipitation (141 years : A.D. 1858∼1998) of Mt. Sorak region (East-central Korea) was reconstructed using a tree-ring chronology of Pinus densiflora sampled from Beakdam Shelter area. During the reconstructed Periods, dry periods were 1880∼1887, 1893∼1901 and 1922∼1938, and wet one 1906∼1918. In the long-term variation, the late 19th and early 20th century were drier than the late 20th century. Major wet/dry periodicities in April∼August precipitation series reconstructed were 3.16 and 4.14 years, indicating that short-term variation were more prominent than long-term one.

      • KCI등재후보

        자기연마법에서 자극 진동 효과

        박원규,최환,노태우 한국기계가공학회 2005 한국기계가공학회지 Vol.4 No.1

        An internal finishing process by the application of magnetic abrasive finishing has been developed as a new technology to obtain a fine inner surface of pipe. In this paper, another method of magnetic abrasive machining in which the N and S magnetic poles are vibrated and a workpiece is rotated only is tried in a non-ferromagnetic pipe(SUS304), and its finishing characteristics is experimently investigated by various effective factors such as vibrating frequency and amplitude. From the experimental results, it is found that the vibration effects of magnetic poles on the finishing characteristics are large in internal finishing

      • KCI등재후보

        충북 영동 성산 배씨 문중 목관의 연륜연대 분석

        박원규,김문성 호서고고학회 2008 호서고고학 Vol.0 No.18

        The study was carried out to analyze tree-ring dates of 6 coffin woods of Bae(Seongsan)- Family, excavated in Yougsanmyeon, Youngdong, Chungbuk, Korea. Tree-ring dates provides a calendar year to annual ring and cutting year if the bark present. Results of tree-ring dating indicated the coffin wood of Bae Chun-Jo was cut in A.D. 1622. The coffin of Bae Chun-Jo's wife was dated as A.D. 1609. They completed latewood, so the cutting season of the tree for Bae Chun-Jo's coffin turned out between 1622 autumn and 1623 spring, Bae Chun-jo's wife coffin between 1609 autumn and 1610 spring. Coffin of Bae Sang-Gyung(son of Chun-Jo) was dated as 1690+year, Bae Si-Ik(grandson of Chun-Jo) as 1682+, Bae Sae-Gwang (great-grandson of Chung-Jo) as 1701+ and Bae Sae-Gwang's wife as 1696+. In fact, due to the seasoning and storage periods, actual coffin manufacturing and burial times may be a little different from the tree-ring dates.

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