족근관에 발생한 결절종으로 인한 족근관 증후군의 치험 1례

설철환,남상현,정윤규 대한성형외과학회 2006 Archives of Plastic Surgery Vol.33 No.5

Purpose: Tarsal tunnel syndrome is characterized by pain and paresthesia of the entire posterior tibial nerve and its branches of the lower extremity. The cause of the tarsal tunnel syndrome is usually unknown but, rare case of space occupying benign tumors such as a ganglion may be one of the causes. We report our experiences of surgical treatment of the tarsal tunnel syndrome caused by ganglion we have encountered recently.Methods: A 54-year-old male patient presented with paresthesia, burning pain, positive Tinnel's sign without preceeding trauma, infection or any other causes of event. With surgical intervention, we completely removed the space occupying ganglion and with performed surgical release of the posterior tibial nerve and its branches. Results: At a 14-month follow up examination, the symptoms of paresthesia, burning pain, sensory disturbance was much improved compared to the preoperative conditions. Takakura's rating scale was elevated from 4(Poor) to 8(Good).Conclusion: We report our surgical experience of a rare case of tarsal tunnel syndrome caused by a ganglion, with a review of literature.

새로운 PGE₁인 Lipo-AS013이 피판의 혈류와 생존에 미치는 영향

설철환,최종우,지용훈,탁관철,Seul, Chul Hwan,Choi, Jong Woo,Chi, Yong Hoon,Tark, Kwan Chul 대한성형외과학회 2005 Archives of Plastic Surgery Vol.32 No.1

Prostaglandin $E_1$($PGE_1$) is known to have various physiological action such as vasodilatation, decrease of blood pressure, angiogenesis, inhibition of platelet aggregation and so forth. $PGE_1$ has been developed in many different formulations in order to overcome its chemical instability and deactivation in the lungs when administered parenterally. Lipo-AS013 is a potent drug with higher chemical stability and greater vascular wall targeting than others. The study was done on $3{\times}10cm$ model flap of dorsal skin of Sprague-Dawley rats and the flap perfusion survival were observed and documented. The flap treated with Lipo-AS013 beforehand was given intravenously Sodium fluorescein 10 minutes later, and then Percent Dye Fluorescence Index(% DFI) was calculated. The results were compared to a control group and the group administered locally epinephrine.. In the control group, the % DFI and flap survival rate increased from $54.1{\pm}6.7$ to $65.0{\pm}2.6$(p<0.01) while in Lipo-AS013 group from $55.3{\pm}2.2$ to $67.4{\pm}1.9$(p<0.01), respectively. In the epinephrine group, the % DFI(p<0.05) and flap survival rate(p<0.001) decreased. In the both epinephrine and Lipo-AS013 group Percent DFI and flap survival rate are comparable with the control group.The result indicates that the potent Lipo-AS013 enhances the blood flow and flap survival. This highly potent Lipo-AS013 may have targeting ability and accumulate $PGE_1$ onto the vascular walls. A quantitative analysis of fluorescence on the skin surface is a reliable tool to measure the blood perfusion into an ischemic flap and its viability. Further comparative study with conventional $PGE_1$ and Lipo-$PGE_1$ is needed in order to clarify the action and efficiency of Lipo-AS013.

괴저성 농피증의 수술적 치험례

설철환,김범진,이성준,김석원,정윤규,Seul, Chul Hwan,Kim, Bom Jin,Lee, Sung Joon,Kim, Sug Won,Chung, Yoon Kyu 대한성형외과학회 2005 Archives of Plastic Surgery Vol.32 No.1

Pyoderma gangrenosum(PG) is an uncommon cutaneous vascular disease that typically presents as a painful and destructive ulceration on the anterior surface of the legs. The etiology of PG is currently unknown. But, the association with many immunologic disorders and its clinical response to immunomodulating agents suggest an immune etiology. A common feature of patients with PG is the presence of pathergy(the induction of lesion following injury of the skin). The trauma of surgery can be sufficient to induce pathergy, thus paradoxically limiting the usefulness of surgical treatment of PG. For that reason, medical treatments have been commonly used, while surgical treatments have been regarded not suitable. However, the use of the classic systemic agents is limited by their side effects and contraindications. Moreover, the large, problematic ulcers take too long to heal with medical management only. We present our experience in closing large wounds with the goal of decreasing morbidity, drug side effects and hospital stay by combination of medical and surgical therapy(split thickness skin graft). And authors advocate that surgical management is not a contraindication and may be considered as a selective modality in treatment of PG.

비공 모양 분석을 이용한 구순열 비변형의 객관적 평가

설철환,박윤규,탁관철,김덕원,박병윤,나동균 대한성형외과학회 2004 Archives of Plastic Surgery Vol.31 No.6

코헤시브 겔 보형물을 사용한 내시경적 겨드랑이절개 유방확대술

설철환 대한미용성형외과학회 2009 Archives of Aesthetic Plastic Surgery Vol.15 No.1

The axillary approach for breast augmentation has held significant appeal to our patients. Its major advantage is the concealed scar at the apex of the axillary fossa. However, this route of access underwent legitimate criticism because of its reliance on blind dissection with the potential for associated secondary problems, such as implant ascension or distortion, implant misplacement, hematoma, or postoperative pain. However, with the use of an endoscopy combined with meticulous surgical technique, many of these problems have been eliminated, and this approach has gained widespread acceptance. The endoscopic approach to transaxillary breast augmentation offers better visualization, more controlled and precise dissection, better control of bleeding, and converting a blind procedure with blunt dissection into the current procedure, in which surgeons are in full control because the surgeons can visualize the field and dissect with precision. Furthermore, the type I dual plane dissection is possible because the surgeons can cut the origin of pectoralis major accurately. Endoscopic techniques have also improved the predictability of postoperative results and increased the safety of patient. In addition, the endoscopic technique can be used in various ways, such as subpectoral, subglandular, and subfascial dissection, as well as capsulotomy or supracapsular dissection in secondary operation cases.

Adriamycin 주입후 생긴 조직손상에 대한 Hydrocortisone의 억제효과

설철환,이혜경,탁관철 大韓成形外科學會 1999 Archives of Plastic Surgery Vol.26 No.4

The objective of this study was to clarify the different inhibitory effects against necrosis according to the injection time of hydrocortisone on adriamycin extravasated wounds. The extravasation of chemotherapeutic agents yields severe inflammatory responses, crust formation, skin necrosis, and ulceration. Thus, many studies on the prevention and alleviation of this tissue injury have been made. However, a comparative study on the inhibitory effect of antidots according to the injection time after extravasation of chemotherapeutic agents has not yet been made. We compared the effect of hydrocortisone succinate on adriamycin-induced tissue necrosis according to its injection time. Sixty mature male Sprague-Dawley rats were divided into 6 groups and each group contained 10 rats. Administration of adriamycin(1.0㎎/ml) 0.5ml by subcutaneous injection on the dorsal side of the rats was followed by injection of hydrocortisone succinate(20㎎/ml) 0.5ml on the same site according to a time protocol. Group 1(the co-ntrol group): adriamycin injection only; gorup 2(the normal saline group): injection of normal saline 30 minutes after adriamycin injection; group 3: injection of hydrocortisone 30 minutes after adriamycin injection; group 4: injection of hydrocortisone 6 hours after adriamycin injection; group 5: injection of hydrocortisone one day after adriamycin injection; group 6: injection of hydrocortisone 3 days after adriamycin injection. Mean areas of ulcer, measured in ㎟, which developed 4 week after adriamycin injection were as follows; group 1 (the control group): 67.3; group 2(the normal saline group):44.8; group 3: 12.9; group 4: 18.9; group 5: 46.7; group 6:72.0. Significant differences among the groups were noted. The groups which received hydrocortisone injection showed smaller ulcers compared to the control group or the normal saline group. As well, earlier injection time correlated with smaller ulcer formation. These findings showed the inhibitory effect of hydrocortisone succinate on tissue damage caused by adriamycin, as well as the increased effectiveness of the inhibitory effect when earlier injections were made. An analysis of this study can be applied in clinical situations for extravasation of adriamycin by administering proper agents such as hydrocortisone succinate. The administration of these agents will also help to minimize tissue necrosis.

광범위 종양절제술 후 발생한 하악 결손의 재건

설철환(Chul Hwan Seul),이영대(Young Dae Lee),탁관철(Kwan Chui Tark),유대현(Dae Hyun Lew) 대한두경부종양학회 2005 대한두경부 종양학회지 Vol.21 No.2

Background and Objectives: Fibula is the flap of choice for reconstruction of wide mandible defects after tumor ablation surgery. In mandible reconstruction, restoring the mandible frame to provide mandibular contour and dental arch while restoring masticatory function are important. Even though vascularized fibula can be osteotomized freely, proper design and flap insetting is not easy because of its three dimensional structure and difference in design according to the defect sites. We reviewed patients who underwent mandible reconstruction with fibular flaps according to the defect sites and suggest proper modification methods of fibular flap according to the various defects sites after tumor ablation surgery. Materials and Methods: Twelve consecutive mandible reconstruction with fibular free flaps were performed for defects after tumor ablation surgery. Patients were classified into 4 groups according to the type of mandibular defect(Group 1 : defect on central segment including symphysis, Group 2 : defect on lateral segment(with or without central segment) confined to body, Group 3 : defect on body and ascending ramus that does not include the condyle, Group 4 : defect including the condyle). Results: We suggest different modification methods of fibular free flap for each patient group. Group 1, 3 ; contour by using multiple closing wedge osteotomy. Group 2 ; single or double barrel reconstruction without wedge osteotomy. Group 4 ; contour using single or multiple wedge osteotomy and condylar reconstruction with costochondral graft. Conclusion: Fibular free flaps can be contoured to any desired shape after multiple osteotomies to restore various mandibular defects. It is a reliable and versatile method for reconstruction of mandibular defects after tumor ablation surgery.

배양된 인체 혈관내피세포에서 유해산소군에 대한 Polyphenol의 보호 효과

탁관철,설철환,김주봉,나동균 대한성형외과학회 2004 Archives of Plastic Surgery Vol.31 No.6

Minimizing the Gap between Expectation and Outcome in Breast Augmentation

황진,설철환 대한미용성형외과학회 2015 Archives of Aesthetic Plastic Surgery Vol.21 No.3

Background Most patients who desire breast augmentation have higher expectations than the outcomes that can be achieved. The purpose of this article is to propose strategies for coping with each patient’s expectation, and selecting the most appropriate surgical method. Methods Data were retrospectively reviewed for 138 women who underwent breast augmentation between July 1, 2012 and June 30, 2014. The augmentation methods were selected based on the patients’ expectations. According to each expectation, we recommended the optimal procedure and material for each patient, and performed the augmentation in accordance with this as much as possible. The patients were asked postoperatively whether they were satisfied with their outcomes. Results Most patients (85%) were satisfied with their results during the mean postoperative follow-up period of 21.4 ± 7.6 months (range, 8–32 months). The remaining, dissatisfied patients (15%) accepted their final results after receiving explanations or additional procedures. Conclusions We classified common expectations of breast augmentation patients into nine categories. To minimize the gap between expectations and outcomes, we preoperatively provided realistic explanations about the limitations of the chosen materials and surgical methods with each patient. We then performed breast augmentation in consideration of the patient’s expectations. Consequently, we were able to appropriately deal with each patient’s expectations.

자가 경구개점막 이식을 이용한 하안검 퇴축의 교정: 2례 보고

김진오,설철환,노태석,유원민 대한성형외과학회 2006 Archives of Plastic Surgery Vol.33 No.4

Purpose: Grave's disease is an autoimmune disease with chronic and systemic features. It affects the orbital fat and muscle bringing about defect in extrinsic eye motility, diplopia, optic nerve defect and lid retraction. In patients with lagopthalmos and resulting facial deformity, treatment can be done by rectus muscle recession or filling with various material. Autogenous auricular cartilage graft is often used and synthetic material such as synthetic acellular dermis, polyethylene meshs are also used for filling of the depressed area. Nevertheless, autogenous auricular cartilage grafts are difficult to utilize and synthetic materials sometimes result in protrusion or infection. Therefore, hard palate mucosa was considered as an alternative. We report two cases of patients with lower eyelid retraction corrected with autogenous hard palate mucosa.Methods: We performed this operation in two patients of Graves' ophthalmopathy. The capsulopalpebral fascia was incised and elevated through an incision on the conjunctiva. Then, the harvested hard palate mucosa was sutured to the inferior border of the tarsus and covered with the conjunctiva. Results: The lower eyelid retraction was corrected successfully. No hypertrophy or deformation of the transplanted hard palate mucosa was noted 6 months after the surgery. Conclusions: From the results above, we may conclude that the hard palate mucosa serves as an ideal spacer for the curvature and the inner lining in lower lid retraction. Hard palate mucosa is as sturdy as the autogenous cartilage but is much easier to utilize. It can be also used for lid retraction after lower lid aesthetic surgeries or traumas.