0D 모델을 활용한 메탄-수소 혼소에 따른 MILD 연소 및 NOx 배출 특성 해석 연구

안소정,박진제,배윤상,이영재 한국수소및신에너지학회 2022 한국수소 및 신에너지학회논문집 Vol.33 No.4

Hydrogen with high chemical reactivity and combustion efficiency, is expected to reduce greenhouse gas and CO emission. However, there is a pro- blem of increase in NOx emission due to hydrogen combustion. MILD combus- tion technology has been proposed to resolve NOx emission. In this study, the characteristics of MILD combustion and NOx formation by flue gas recirculation (KV) in CH4-H2 mixture were analyzed and predicted using 0D premixed combus- tion model. The ignition delay time became shorter as the hydrogen co-firing rate increased, and longer as the recirculation rate increased. For NOx emission, EINO decreased as the KV increased, but EINO increased as the hydrogen co- firing rate increased. In particular, EINO was predicted to increase significiently above 80% hydrogen. Through the pathway analysis of NO formation, it was found that the influence of N2O intermediate route and NNH route was enhanced for hydrogen co-firing.

Vancomycin 약동학적 자문결과 분석

안혜림,배성미,홍경자,나현오 한국병원약사회 2000 병원약사회지 Vol.17 No.2

The results of therapeutic drug monitoring (TDM) service were evaluated. Total 78 cases of peak and trough concentration of vancomycin were obtained on steady state. The 54 cases of all were obtained prior to TDM service. Statistically significant differences were observed between population vancomycin clearance by CAPCIL® computer program and Bayesian clearance by Bayesian method. Only 48.1% of the 54 cases given empirical dose of vancomycin were within therapeutic range. After TDM service, 23% (18/78 cases) were recommended dose reduction and 66.7% (12/18 cases) were accepted. Drug concentration were obtained from 15 cases who received modified dose through TDM service and 13 cases of them were within expected range. The total drug saving were 257 vials in 9 patients who were administered reduction dose (9/54 cases) and the calculated mean cost saving per case was 321,907 won (range : 78,911~473,466). In conclusion, TDM service for vancomycin is necessary to obtain optimal therapeutic drug level and for the cost saving. Furthermore the vancomycin dosing nomogram in Korean population should be developed.

비도덕성이 광고에 대한 태도에 미치는 영향 : 도덕성-깨끗함의 관계를 중심으로

배인해,오트나산 오트곤토야,안유현,정혜욱 한국전략마케팅학회 2016 마케팅논집 Vol.24 No.3

본 연구의 목적은 비도덕적 상황에 노출된 소비자들이 깨끗함과 관련된 광고에 어떤 태도를 보이는지 규명하는 것이다. ‘도덕적 순결함’이라는 은유적 표현의 사용은 도덕성과 깨끗함이라는 두 개념을 상호활성화 시킨다. 따라서 비도덕적 상황을 접한 소비자는 더럽혀진 도덕적 가치를 복구하기 위해 깨끗함과 관련된 광고에 대해 더 긍정적인 태도를 보일 것이라고 예측하였다. 실험 1은 비도덕성 조작 후 신체 외부를 깨끗하게 해주는 제품을 포함한 광고(치약 vs. 초콜릿)에 대한 태도를 측정하였으며, 실험 2는 신체 내부를 깨끗하게 해주는 제품을 포함한 광고를 대상으로 삼았다(디톡스 주스 vs. 초코 음료). 실험 3은 같은 제품군을 대상으로 광고 문구(세척 작용 vs. 잇몸 보호)만 다르게 설정하여 비도덕성이 광고 태도에 미치는 영향을 알아보았다. 세 가지 실험 모두 비도덕적 행위를 경험한 참가자들이 그렇지 않은 참여자들보다 깨끗함과 관련된 광고에 대해 더 긍정적인 태도를 보였다. 마지막으로 조사결과를 바탕으로 이론적 및 실무적 시사점과 한계점에 따른 미래 연구방향을 제시하였다. The purpose of this study is to examine whether immorality influences attitudes toward the advertisements related to cleanliness. Using a metaphoric expression ‘moral purity’ co-activates two concepts: morality and cleanliness. We predicted that consumers who experienced immoral situation will show positive attitudes toward the cleanliness-related advertisements to cleanse their moral disgust and to reaffirm their violated moral values. Experiment 1 manipulated immorality and measured attitudes toward the two advertisements(toothpaste vs. chocolate). Experiment 2 included a product that cleanses inner parts of the body(detox beverage vs. chocolate beverage). Experiment 3 advertised the same product with two different messages(washing action vs. gum protection). Participants primed with immorality showed more positive attitudes toward the cleanliness-related advertisement than those who are not. The theoretical and practical implications are discussed. The limitations of this study are suggested for the future research.

장천공과 Enteritis Cystica Profunda를 동반한 Peutz-Jeghers 증후군

안기성(Ki Sung Ahn),배정동(Jung Dong Bae),김호각(Ho Gak Kim),손호상(Ho Sang Shon),최정윤(Jung Yoon Choe),김지희(Chi Hui Kim),김이근(Ih Geun Kim),김태석(Tae Sug Kim),김채기(Chae Gi Kim) 대한소화기학회 1997 대한소화기학회지 Vol.29 No.5

The Peutz-Jeghers syndrome is an autosornal dominant condition characterized by mucocutaneous pigmentation and hamartomatous polyps of the gastrointestinal tract. This syndrome is clinically important because of complications caused by gastrointestinal polyps, such as abdorninal pain, gastrointestinal bleeding and intussusception often leading to intestinal obstruction. The possibility of malignant change in the polyp has been a controversial issue. In the recent reviews of soe cases of Peutz-Jeghers syndrome, the reported lesions of small intestinal adenocarcinoma are regarded as the benign process of enteritis cystica profunda. We present herein a case of Peutz-Jeghers syndrome with small bowel perforation, a previously unreported instance, and enteritis cystica profunda. (Korean J Gastroenterol 1997; 29:677-682)

GMP-based development of biopharmaceuticals

배경동,안상점,허병기 한국공업화학회 2007 한국공업화학회 연구논문 초록집 Vol.2007 No.1

한국 주식시장에서의 유동성위험의 평가

배성미,김종대,안형태,조문기 한국기업경영학회 2016 기업경영연구 Vol.23 No.4

This study investigates if liquidity risk can explain individual stock returns as a systematic risk in the Korean stock market. And, it examines whether market liquidity and its unexpected change increase at times of liquidity crisis such as the foreign currency crisis during 1997-1999 and the global financial crisis during 2007-2009 periods. It also tests if the liquidity risk itself, a sensitivity of individual stock return to unexpected change in market liquidity, increases at times of liquidity crisis. The final sample of 139,468 firm-months for periods of 1992∼2012 that satisfy the sample selection criteria. All sample firms are listed in the Korean stock market. The results indicate that the liquidity risk is evaluated by the investors as a systematic risk in addition to the market beta, firm size and book-to-market ratio that are known as systematic risks. That is, a significant positive correlation was found between unexpected change in market liquidity and individual stock returns, consistent with the prior studies. It indicates that the liquidity risk is recognized as an additional source of systematic risk in the Korean stock market. The result implies that the more sensitive a stock is to the unexpected change in market liquidity, the higher liquidity premium is required by the investors. Analysis of the monthly movement of liquidity in the Korean stock market reveals that the market liquidity and its unexpected change increased sharply around the foreign currency crisis and the global financial crisis. It also shows the increase of liquidity risk, the sensitivity of individual stock return to the unexpected change in market liquidity, at times of liquidity risk. Many incidents have been occurring that bring about turbulences in financial market after the global financial crisis, and one of the underlying causes is referred to as lack of liquidity in the financial market. This study provides to the finance literature evidence of liquidity risk functioning as an additional source of systematic risk at Korean stock market, and it finds out that the liquidity risk itself differs depending on the level of market liquidity. This study contributes to the extant literature by presenting an additional evidence of liquidity risk as an additional systematic risk in the Korean stock market based on different sample period encompassing a world financial crisis. In addition, it uses a different definition and measurement of liquidity risk than the previous study. Despite those differences, this study ascertains the liquidity risk as a source of systematic risk in the Korean stock market. The result indicates that liquidity risk must be taken into account along with well-known risk factors in estimating expected return from assets. Also, it needs to be noted that unusual movement of liquidity at times of financial crisis increases the systematic risk of stocks. 본 연구의 목적은 국내 주식시장을 대상으로 유동성위험(liquidity risk)이 개별 기업의 기대수익률을 설명하는 체계적 위험 요인으로 작용하고 있는지를 검증한다. 또한 외환위기와 세계금융위기와 같은 유동성 위기 기간에 시장유동성과 비기대 시장유동성 변동이 어떠한 양상을 보이는지를 살펴보고, 이 시기 유동성위험의 크기가 그렇지 않은 기간과 어떠한 차이를 나타내는지를 확인하고자 한다. 이를 위해 1992년∼2012년까지 한국증권거래소에 상장된 기업들 중 표본 선정 기준을 만족한 139,468 기업-월 표본을 대상으로 실증분석을 실시한 결과, 이전 연구에서 개별 주식의 기대수익률에 영향을 미치는 요인들로 확인된 시장베타, 기업규모, BE/ME ratio를 통제한 후에도 유동성위험 변수와 개별 주식 초과수익률 간에 유의한 양(+)의 상관관계가 있음을 확인하였다. 이는 비기대 시장유동성 변동에 민감한 주식일수록 높은 유동성 프리미엄을 요구하고 있음을 보여준다. 본 연구의 결과는 해외 연구와 일관되는 것으로 국내 주식시장에서도 유동성위험이 존재하며, 시장참여자들에 의해 체계적 위험 요인으로 평가되고 있음을 제시한다. 월별 시장유동성 및 비기대 시장유동성 변동 패턴을 살펴본 결과에서도 1997년 외환위기와 2007년 세계금융위기 당시 우리나라 주식시장에서도 시장유동성뿐만 아니라 비기대 시장유동성 변동이 급격하게 증가하였으며, 유동성위험도 함께 증가하는 것으로 나타났다.

반코마이신의 임상약동학 모니터링 서비스에 대한 임상적 및 경제적 손익의 평가

배성미,안혜림,홍경자,나현오,조혜경 한국임상약학회 2001 한국임상약학회지 Vol.11 No.1

This research is conducted to evaluate the clinical and economic benefits from therapeutic drug monitoring(TDM) service on vancomycin in a tertiary general hospital. Total 99 pairs of steady state peak and trough concentrations of vancomycin were obtained from 73 patients. To see the clinical benefits, the appropriateness of vancomycin dosing before TDM was evaluated. In 72 pairs of vancomycin blood concentrations obtained prior to TDM consultation, of the cases had reached within therapeutic range. Serum vancomycin levels in patients with $40{\leq}CLcr<60$ (ml/min) were higher and than the levels in patients with 40>CLcr and (ml/min). Dose reduction rate in patients with creatinine clearance $40{\leq}CLcr<60$ (ml/min) were also significantly higher than those of compared groups (, p=0.0138). Serum vancomycin concentrations were re-obtained from 21 patients who received modified dose through TDM service. Ninety percent (19/21cases) of them were within the target therapeutic range. For the evaluation of economic benefits from TDM consultation, estimated cost savings were calculated in those patients. The total drug saving were 586 vials in 21 patients. The calculated mean cost saving from the drugs was 314,570 won (range: per patient. The study revealed that TDM service for vancomycin is necessary because empirical dosing is not effective for obtaining therapeutic drug level, especially patients with mild renal insufficiencies. The cost saving from TDM is also beneficial for the patients.

Boundedness of min/max eigenvalues of an edge-symmetric rigidity matrix

배유빈,안효성 제어로봇시스템학회 2021 제어로봇시스템학회 국내학술대회 논문집 Vol.2021 No.6

시장유동성 위험과 회사채 신용등급

안형태,배성미,조문기 한국회계정보학회 2019 회계정보연구 Vol.37 No.3

The study investigates the effect of liquidity risk on the corporate bond ratings. Liquidity risk is defined as a sensitivity of individual stock return to the unexpected change in market liquidity. It also examines the moderating effect of the family ownership as well as whether the companies are family business or not. Sample consists of 1,220 listed firm-years for which information on the credit rating is available during 2011 to 2016. The results show that firms with high liquidity risks have lower credit ratings. In addition, the negative effect of liquidity risk on the bond rating is lower (strengthened) for family business and for ones with higher family ownership. The study indicates that liquidity risk is priced as one of the systematic risks and determinants of firm value in Korean stock market. It contributes to the extant literature and the practice by providing various stakeholders concerning corporate bond issuance with the significance of liquidity risk and the impact of family business ownership. 본 연구의 목적은 비기대 시장유동성 변동에 대한 개별기업의 주식수익률 민감도로 정의되는 시장유동성 위험이 회사채 신용등급에 미치는 영향을 검증함과 동시에, 기업지배구조 요인 중 하나인 가족기업 여부 및 가족기업 소유지분율에 따른 차별적 반응을 검증하고자 하는데 있다. 2011년부터 2016년까지의 유가증권 상장기업 중 회사채 신용등급 정보가 제공된 1,220개 기업-연도 표본을 대상으로 분석을 실시하였다. 실증분석 결과, 시장유동성 위험이 높은 기업일수록 회사채 신용등급이 낮은 것으로 나타났다. 또한 유동성 위험이 회사채 신용등급에 미치는 부정적 영향은 가족기업 형태의 소유구조를 띄는 기업, 그리고 가족기업 소유지분율이 높은 기업들이 그렇지 않은 기업들에 비해 낮은 것으로 나타났다. 본 연구의 결과는 국내 자본시장에서도 시장유동성 위험이 체계적 위험 요소 중 하나로 평가되고 있고, 결국 기업 가치의 결정요인으로 작용하고 있음을 실증하였다는 점에서 학문적 의의가 있다고 하겠다. 또한 우리나라 기업의 특수한 지배구조 형태라고 할 수 있는 가족기업 요인에 따른 차별적 반응을 검증함으로써 회사채 발행과 관련된 다양한 이해관계자들의 의사결정에 중요한 시사점을 제공하였다는 점에서도 그 의의가 크다고 하겠다.

미코노미(Meconomy)현상에서 1인 가구의 여행 안전, 긍정심리자본과 여행 만족에 관한 연구

안현영 ( Ahn Hyun-young ),배연주 ( Bae Youn-joo ) 동북아관광학회 2021 동북아관광연구 Vol.17 No.1

본 연구는 1인 가구원이 인식하는 긍정심리자본과 여행 안전이 여행 만족에 미치는 영향을 실증적으로 분석하였다. 연구결과는 다음과 같다. 첫째, 1인 가구의 여행행태분석에 의하면 국내 여행 횟수는 1-3회가 가장 많았으며, 국내 여행 일수는 1박 2일과 2박 3일이 많았다. 숙박 형태는 호텔이 가장 많았으며, 동반 형태로는 친구, 연인, 가족의 형태로 분석되었다. 둘째, 1인 가구의 여행 안전에 대한 요인 분석은 안전교육, 안전기술, 안전규제의 3개 요인으로 적재되었으며, 긍정심리자본의 요인은 낙관주의, 회복 탄력성, 희망, 자기효능감으로 도출되었다. 셋째, 여행 안전과 여행 만족에 관한 분석에서는 여행 안전 하위 요인 중에서 안전 규제 요인이 여행 만족에 영향을 미쳤지만, 안전기술과 안전교육은 여행 만족에 영향을 미치지 않는 것으로 분석되었다. 넷째, 1인 가구가 인식하는 긍정심리자본과 여행 만족의 관계를 회귀분석한 결과, 긍정심리자본의 하위 요인 중에서 회복탄력성 요인이 여행 만족에 영향을 미치는 것으로 분석되었다. This study empirically analyzed the effects of travel safety and positive psychological capital perceived by single-person household members on travel satisfaction. The results of this study are as follows. To begin with, according to the analysis of travel behavior of single-person households, the number of domestic travels was 1-3 times, and the number of domestic travel days was 1 night 2 days and 2 nights 3 days. Hotels were the most common and preferred type of accommodation, and friends, intimate partners, and family were analyzed as the companion type. Second, the factor analysis of travel safety of single-person households was loaded with three constituents: safety education, safety technology, and safety regulation. The factors of positive psychological capital were derived from optimism, resilience, hope, and self-efficacy. Third, in the analysis of travel safety and travel satisfaction, safety regulatory factors among travel safety sub-factors affect travel satisfaction, but safety technology and safety education have not been identified. Finally, as a result of regression analysis on the effect of positive psychological capital perceived by single-person households on travel satisfaction, it was analyzed that resilience factor among the sub-factors of positive psychological capital displayed no influence on travel satisfaction.