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      • KCI등재

        오적산(五積散)을 투여한 흰쥐의 간장, 신장, 골중 금속농도 비교에 관한 연구

        박철수,이선동,박해모,박영철,Park Chul-Soo,Lee Sun-Dong,Park Hae-Mo,Park Yeong-Chul 대한예방한의학회 2002 대한예방한의학회지 Vol.6 No.2

        Traditional herbal medicine is used extensively among the Korean populations, and other Asian countries employ similar therapies as well In recent years, extensive focus was laid on adulteration of the herbal medicine with heavy metals. This may be mainly due to a soil contamination by an environmental pollution. The objective of this study is to identify the contents of various heavy metals in the blood from OhJeokSan-Decoction (OD) treated-rats. For this study, 13 kinds of metals including essential and heavy metals, i.e. Al, As, Cd, Co, Cr, Cu, Fe, Hg, Mn, Ni, Pb, Se and Zn were analyzed by a slight modification of EPA methods and the following results are obtained. ; 1. There is no significant difference between the OD-treated groups and control group in liver, kidney, bone, brain, weight, food intake. 2. The amount of each metal analyzed in the liver are as follows; Al ; $0.235{\sim}4.215mg/kg$, As ; $0.103{\sim}0.461mg/kg$, Cd ; $0.005{\sim}0.010mg/kg$, Co ; $0.017{\sim}0.046mg/kg$, Cr ; $0.137{\sim}0.403mg/kg$, Cu ; $1.736{\sim}4.827mg/kg$, Fe ; $54.472{\sim}381.447mg/kg$, Hg ; not detected, Mn ; $1.159{\sim}2.803mg/kg$, Ni ; $0.007{\sim}0.095mg/kg$, Pb ; not detected, Se ; $0.682{\sim}1.887mg/kg$, Zn ; $10.213{\sim}26.119mg/kg$, by groups, respectively. In control and other experimental group, several metal (Co, Cu, Mn, Zn, As, Cr) has a significant difference, but in experimental I and other experimental II, III, IV, V groups, there are no significant difference. 3. The amount of each metal analyzed in the kidney are as follows; Al ; $1.712{\sim}31.230mg/kg$, As ; $0.062{\sim}0.439mg/kg$, Cd ; $0.010{\sim}0.062mg/kg$, Co ; $0.000{\sim}0.101mg/kg$, Cr ; $0.125{\sim}0.636mg/kg$, Cu ; $3.385{\sim}12.502mg/kg$, Fe ; $41.148{\sim}99.709mg/kg$, Hg ; $0.000{\sim}0.270mg/kg$, Mn ; $0.433{\sim}2.301mg/kg$, Ni ; $0.000{\sim}0.221mg/kg$, Pb ; $0.000{\sim}0.584mg/kg$, Se ; $0.540{\sim}1.600mg/kg$, Zn ; $8.775{\sim}17.060mg/kg$, by groups, respectively. The concentration of Cu, Se, Cr, and Hg are variated significantly in control and other experimental group, and Cu, Se, Cd, Cr are variated significantly in experimental I and other experimental II, III, IV, V groups. 4. The amount of each metal analyzed in the bone(tibia and fibula) are as follows; Al ; $9.557{\sim}119.464mg/kg$, As ; $0.139{\sim}12.250mg/kg$, Cd ; $0.000{\sim}0.295mg/kg$, Co ; $0.022{\sim}0.243mg/kg$, Cr ; $0.239{\sim}1.999mg/kg$, Cu ; $0.000{\sim}2.291mg/kg$, Fe ; $240.249{\sim}841.956mg/kg$, Hg ; $0.000{\sim}0.983mg/kg$, Mn ; $0.214{\sim}7.353mg/kg$, Ni ; $5.473{\sim}11.453mg/kg$, Pb ; $0.000{\sim}8.502mg/kg$, Se ; $0.000{\sim}3.005mg/kg$, Zn ; $61.158{\sim}195.038mg/kg$, by groups, respectively. The concentration of Se, Cd are variated significantly in control and other experimental groups, and Se is variated significantly in experimental I and other experimental II, III, IV, V groups. 5. Exceptionally several metal concentration is increased or decreased. but there is no significant harmful difference of metal concentration in the liver, kidney and bone, from the OD-treated-rats compared to those of the control group even if higher dosage($1{\sim}8$ times dosage of person) of OD was administered. Thus, it is expected that the herbal decoction in the traditional herbal medicine would not lay any burden on the body and the heavy metal toxins would not affect our physiological system. However, other kinds of herbal treatment, such as i.v. and i.p. should be considered in terms of

      • KCI등재

        박완서의 문학작품을 통해 본 서울 주거공간의 이분법적 시각

        박철수,Park Cheol-Soo 한국주거학회 2006 한국주거학회 논문집 Vol.17 No.2

        The exploration of the spatial structure of a particular urban area, or the analysis of the tendencies of spatial consumption among urbanites, can be a literary-geographical attitude, shifting literary interests toward geography. It may also constitute a field of cultural geography that reads texts as cultural symbols. Based on this kind of attitude, the paper reads the literature of Park Wan So, particularly the popular novels that involve urban and residential spaces of Seoul, as a cultural text that carries a kind of symbolism. It proceeds with the idea that most popular novels reflect the mass phenomena of its times, and that representing real cultural experiences through text, it becomes a means of generalizing the identity shared by the anonymous masses and the characteristics of particular places. Hence the individuality of Park Wan So, who moved to Seoul during the Japanese colonial period and hence forth lived as a middle-class citizen, is inseparable from her literary work. With this attitude and methodology, the paper argues that in the urban space of metropolitan Seoul, the modern ambivalent gaze of the colonial period shifted toward increasingly new value systems, and was replaced by a dichotomous view, and furthermore, that the contents of this dichotomous view has experienced a multivalent transformation through the accumulation of time and the expansion of space.

      • KCI등재

        정합장 처리를 이용한 캐비테이션 터널에서의 프로펠러 소음원 위치 추적에 관한 연구

        박철수,조용진,설한신,Park, Cheol-Soo,Cho, Yong-Jin,Seol, Han-Shin 한국음향학회 2007 韓國音響學會誌 Vol.26 No.5

        캐비테이션 터널에서 소음계측 실험의 주 목적은 프로펠러 소음레벨 계측과 소음원의 위치 판별이다. 한국해양연구원의 소음계측 실험용 "저소음 대형 캐비테이션 터널"의 기초연구의 일환으로 소음계측 실험이 동 연구원의 소형 캐비테이션 터널에서 수행되었다. 본 실험에서는 프로펠러 캐비테이션이 발생할 수 있는 반류조건을 만들기 위해 반류 생성용 모형체(dummy body)를 제작하였고, 유동장 내의 청음기에 의한 자체소음을 줄이기 위해 유선형으로 설계된 하이드로포일내에 청음기 배열을 설치하였다. 다양한 압력조건에서 발생한 소음장과 가상 음원의 복제음장을 계측한 후, 소음원의 위치를 추적하기 위해 주파수 비상관 Bartlett 프로세서를 적용하였다. 본 논문에서는 수행된 소음계측 시험에 대해 기술하고, 계측된 소음의 분석 및 위치추적 결과를 제시한다. The two major objectives of acoustical measurements in a cavitation tunnel are measuring the noise levels generated by rotating propellers behind a hull and localizing possible noise sources in order to reduce noise levels. Propeller noise measurement experiments were performed in MOERI cavitation tunnel at December, 2006. In order to put the propeller into cavitating conditions, a wake-generating dummy body was devised. In addition, ten hydrophones are put inside a wing-shaped casing in order to minimize the unexpected flow induced self noise around hydrophone itself. After measuring both of the noises of the rotating propeller behind the dummy body and signals generated by a virtual source, respectively the data were matched field processed using the frequency incoherent Bartlett processor to localize noises on the propeller plane. In this paper, we presented the measured noise analysis and the localization results.

      • KCI등재후보

        AHP를 이용한 의료기기 벤처기업의 신용평가모형

        박철수,김만술,Park, Cheol-Soo,Kim, Mahn-Sool 한국벤처창업학회 2011 벤처창업연구 Vol.6 No.2

        본 연구에서는 최근 꾸준한 성장세를 보이고 있는 의료산업의 국내벤처기업에 대한 신용 평가를 위해 먼저 기업의 재무 요인과 비재무 요인을 구분하여 평가지표를 개발한 다음 Saaty(1980)의 계층분석과정(Analytic Hierarchy Process; AHP)방법론을 적용하여 각 지표의 중요도(가중치)를 산출함으로써 의료벤처기업의 신용평가모형을 제시한다. 재무요인의 상위지표로는 수익성, 안전성, 활동성, 성장성, 생산성을 선택하였고, 각 상위지표에 대해서는 2개씩의 하위지표를 정하여 모두 10개의 지표를 설정하였다. 또 비재무적 요인의 상위지표로는 경영자 능력, 기술성, 시장성, 사업성, 신뢰성의 5개 영역을 정하고, 각 영역에 대해 2-5개의 하위지표를 정하여 모두 17개의 지표를 설정하였다. 신용평가지표에 대한 평가를 위해 원주의료기기클러스터 내 소재하고 있는 금융기관 및 보증기관의 심사역을 대상으로 설문조사를 한 후 이를 분석하여 평가지표에 대한 가중치를 산출하였다. This study presents the credit evaluation model for medical venture business which has been growing within the recent decade. We develop the model with two steps. At the first step, the evaluation indexes for each of the financial and non-financial factors of a firm are listed. At the second step, the weight for each index is measured by using the Analytic Hierarchy Process of Saaty(1980). The financial factors consists of 5 upper level indexes and 10 lower level indexes. The upper level indexes of the financial sector are profitability, safety, utilization, growth, and productivity. And the non-financial factors consists of 5 upper level indexes and 17 lower lever indexes. The upper level indexes in this sector are manager's competence, technical capability, marketability, business validity, and reliability. In order to get the empirical results for our model, we conduct the questionnaire survey targeting the credit assessment officers, who are practicing at the financial institutions or the credit guarantee company located within the Wonju Medical Devices Cluster.

      • KCI등재

        천해 음파전달 모의에 적합한 음선기반 광대역 신호 모델링 기법에 관한 연구

        박철수,조용진,안종우,성우제,Park Cheol-Soo,Cho Yong-Jin,Ahn Jong-Woo,Seong Woo-Jae 한국음향학회 2006 韓國音響學會誌 Vol.25 No.6

        본 논문에서는 천해 음파전달 모의에 적합한 음선기반 광대역 주파수 신호 모의기법을 제안하였다. 본 기법은 깊이에 따라 음속이 선형적으로 변하는 환경 및 층매질에서의 음선추적을 기반으로 평면파 및 구형파의 반사 및 투과, 굴절 그리고 감쇠 등을 고려해 각 고유음선의 위상 및 크기로부터 신호를 모의한다. 본 기법의 가장 큰 특징은 주파수영역을 거치지 않고 시간영역에서 이산화된 신호를 직접 모의함으로써 주파수 대역에 관계없이 계산시간을 단축할 수 있다는 것이다. 끝으로 제안된 기법을 네 가지의 테스트환경에 적용하여 기존의 검증된 모텔 (ORCA, Ram) 의 결과와 비교하여 그 효용성을 검증하였다 This paper proposes a ray-based forward modeling scheme which is suitable for the shallow water acoustic wave propagation simulations. The proposed model comprises of ray tracings for the layered media of which sound speed profiles are interpolated linearly. considerations of plane and spherical wave reflection coefficients. and calculations of the phases and the amplitudes of eigen rays. The main characteristic of the scheme is fast simulation time due to direct calculation of the broad-band time signals in the time-domain, i.e. without transformation of the frequency-domain solutions to the time si 밍 131s. Finally, we applied the model to 4-types of test environments and compared the resulting signals with those of ORCA and Ram in order to validate the proposed model.

      • KCI등재

        오리피스형 공기분사기 생성 기포소음 추정 연구

        박철수,정소원,김건도,문일성,김인강,Park, Cheolsoo,Jeong, So Won,Kim, Gun Do,Moon, Ilsung,Kim, In kang 한국음향학회 2022 韓國音響學會誌 Vol.41 No.3

        In this paper, noise characteristics of bubbles created by an orifice-type bubble generator are studied. In order to understand the overall bubble noise characteristics, the bubble noise spectra proposed by Strasberg and Blake, respectively, are examined, and an air injection experiment was performed in the large cavitation tunnel of KRISO to measure the bubble noise. The experiments were performed under a quiescent condition and flow conditions using 5 types of air bubble generator. From the measurement results, the characteristics of the bubble noise spectrum according to the experimental conditions are observed, and the effect of each parameter on bubble noise is analyzed by regression analysis. Finally, empirical models based on the regression analysis for bubble noise are presented, and it is confirmed that the estimated bubble noise is in good agreement with the measured results.

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