인문사회의학(의료인문학)의 범주와 교육과정 - 한의학 교육 중심으로 -

박해모,선승호,Park, Haemo,Sun, Seung Ho 대한예방한의학회 2021 대한예방한의학회지 Vol.25 No.2

Objective : The definitions and categories of subjects related to humanities and social medicine are still controversial, and we tried to find the areas lacking compared to the standards of medical education Method : Humanities and social medicine-related subjects of the World Medical Education Standards, ASK2019, and KAS2021 were reviewed, and humanities and social medicine subjects of the College of Korean Medicine were searched. We compared subjects with the medical school learning outcomes and Korean Medicine Doctors' job competency. In order to increase validity, two authors independently classified them. In case of different opinions, we revised after sufficient discussion Results : Humanities and social medicine-related subjects in the Korean Medicine curriculum appear to be sufficient when compared with WFME and ASK2019. The humanities and social medicine-related subjects of Korean Medicine schools were not distributed evenly throughout. The areas to be supplemented in Korean Medicine education were 'a diverse understanding of life and death', 'prevention and response to patient safety incidents', 'effective communication with health-related organizations and groups', 'social responsibility and reflective practice' and 'communication between health and medical professions'. Conclusion : Humanities and social medicine-related subjects in Korean Medicine education are sufficient, but they are not evenly distributed, and the areas listed above need to be reinforced.

WFME 2020 개정 3판의 기준과 WFME 2015, KAS 2021 기준 비교

박해모,선승호 대한예방한의학회 2021 대한예방한의학회지 Vol.25 No.1

Objective : We reviewed WFME2020 and compare it with WFME 2015 and KAS2021 to find similarities and differences. It will be used as basic data for future evaluation and certification criteria development. Method : WFME 2020 and WFME 2015 were translated and summarized around the core content. The structure of each standard was analyzed and organized, and then, based on the WFME 2020 standard items corresponding to each item were arranged in the items of WFME 2015 and KAS2021. Two authors translated and compared them separately, and if the content was different or the intention of the translation was different, the final revision was made after sufficient discussion. Results : The WFME 2020 standard consists of 8 major areas and 21 sub-areas. The WFME 2020 has a structural change compared to the 9 major and 35 sub-areas of WFME 2015. The importance of the mission is being emphasized, the curriculum and student selection have been changed so that they can be adjusted according to the local situation, and the areas of evaluation and program evaluation have been strengthened. Conclusion : Overall, the increased autonomy of schools and institutions seems positive from the standpoint of Korean Medicine education evaluation certification, but additional research and education are needed for the strengthened areas. In order to develop the WFME 2020 standard to the certification criteria in the future, in-depth discussion and consensus will be required in consideration of the characteristics of Korean Medicine.

대한예방한의학회지 게재논문의 경향성에 대한 연구 - 창간호(1997년)로부터 2010년까지 -

박해모,Park, Hae-Mo 대한예방한의학회 2011 대한예방한의학회지 Vol.15 No.1

Objective : The purpose of this study was to identify the trend of research in the Korean Journal of Oriental Preventive Medicine and to suggest future perspective for oriental preventive medicine research. Method : The contents of 344 articles published in this journal was reviewed from its beginning year 1997 to year 2010. Result : The number of articles was increased as times go on. An analysis of the research design showed, experimental research (in vivo or in vitro) was 36.9%, survey research was 26.5%, review was 20.1%. In the major classifications of topics published, health management 28.5%, oriental medicine effectiveness 25.3%, herbal safety and toxicity 13.1%, and environmental and occupational medicine 9.0% respectively. Conclusion : There has been a lack of health preservation(Yang-saeng) topic, epidemiology and health statistics topic. Further research need qualitative study and each subjects of oriental preventive medicine.

한약재 복용으로 인한 금속 섭취량 추정 및 위해성 평가 연구

박해모,최경호,정진용,이선동,Park Hae-Mo,Choi Kyung-Ho,Jung Jin-Yong,Lee Sun-Dong 한국환경보건학회 2006 한국환경보건학회지 Vol.32 No.2

Metal contamination of medicinal herbs is of growing concern because of their potential adverse health effects. In this study, metal exposures were estimated and their potential health risks were preliminarily evaluated using available data including metal contamination levels and consumption estimates of herbal medicine in Korea. Consumption and contamination data of 34 medicinal herbs abundantly used in Oriental medicine in Korea were used in this study. Lead, mercury, arsenic, cadmium, cobalt, and chrome were identified as contaminants of potential health concerns. Even based on a conservative exposure scenario, i.e., consuming 5 times more herbal medicine with 95th percentile contamination levels, health risks associated with herbal medicine consumption were estimated to be minuscule. Herbal consumption was 0.3% of the provisional tolerable daily intake levels recommended by Joint Expert Committee on Food Additives (JECFA) of WHO/FAO. However, it should be noted that there are several important assumptions and uncertainties associated with this evaluation: This study was conducted for only 34 types of medicinal herbs of which consumption and metal contamination data were available. In addition, there are no reliable herbal medicine consumption data among Korean population. The pattern and amount of herbal (medicine) consumption in Korea need to be investigated in order to conduct more refined risk assessment associated with metal contamination in medicinal herbs.

한약이 실험동물의 태자에 미치는 생식독성학적 영향 -오적산을 중심으로-

박해모,신헌태,이선동,Park, Hae-Mo,Shin, Heon-Tae,Lee, Sun-Dong 대한예방한의학회 2008 대한예방한의학회지 Vol.12 No.2

Purpose : The experiments was undertaken to evaluate the effects of Ojeoksan-herbal medicine, in rats' fetus Methods : Female Sprague-Dawley rats were orally administered with the Ojeoksan at dose of 5mg/kg/day for 20 days. Pregnant rats were sacrificed at 20th day of gestation, and observed internal and reproductive organs. Approximately live fetuses in the 20th day of gestation were randomly selected and fixed in 95% ethanol. Results : Neonatal body weight and number of fetus of Ojeoksan group were increased to that of control group. The fetuses of dams treated with Ojeoksan didn't showed external malformation. Vertebral and sternal skeletal variations were observed in Ojeoksan administered group, but compared to the control, those skeletal variations were insignificant. There were no significant changes in number of ribs, cervical, thoracic, lumber, sacral and caudal Conclusion : From these results, it can be concluded that Ojeoksan showed no toxicity effects on number of live fetuses. There were no significant changes in skeletal variations were showed in vertebrate and sternum, Ojeoksan weren't shown significant changes in bone malformation. We need more precise study to investigate the mechanism of early or late resorption by the herbal medicines such as Ojeoksan.

오적산이 실험동물의 모체에 미치는 생식독성학적 연구

박해모,신헌태,이선동,Park, Hae-Mo,Shin, Heon-Tae,Lee, Sun-Dong 대한예방한의학회 2008 대한예방한의학회지 Vol.12 No.1

Purpose : The experiments was undertaken to evaluate the effects of herbal medicine, Ojeoksan, in pregnant rats Methods : Female Sprague-Dawley rats were orally administered with the Ojeoksan at dose of 5mg/kg/day for 20 days. Pregnant rats were sacrificed at 20th day of gestation, and observed internal and reproductive organs. Approximately live fetuses in the 20th day of gestation were randomly selected and fixed in 95% ethanol. Results : Maternal body weight of Ojeoksan treated group has a tendency to increase compared to that of control group. There were no significant difference in internal and reproductive organs. There were no significant changes between two groups in blood chemistry and hematological values. There were no significant changes in number of corpus luteum, implantation, live fetuses and sex ratio. But Ojeoksan administered group showed higher delivery rate, early resorption rate than the control group. Also Ojeoksan administered group showed higher implantation rate, late resorption rate than the control group. Conclusion : From these results, it can be concluded that Ojeoksan showed no toxicity effects on maternal body weight and number of live fetuses. There were no significant changes in organ weight, hematological data, reproductive organs. We need more precise study to investigate the mechanism of early or late resoption by the herbal medicines such as Ojeoksan.

간기능검사이상의 위험요인으로써 한약복용영향에 관한 단면연구

박해모,신헌태,박철수,이선동,Park, Hae-Mo,Shin, Heon-Tae,Park, Cheol-Soo,Lee, Sun-Dong 대한예방한의학회 2008 대한예방한의학회지 Vol.12 No.2

Objectives : The aim of this study was to evaluate effects of herbal medicine and other associated factors for abnormal liver function tests(especially total bilirubin, AST, ALT, and ${\gamma}$GT) levels in outpatients at an oriental medical clinic. Methods : A cross-sectional study based on clinical records was conducted on 504 patients at one Oriental medical clinic in Seoul, Korea. They were tested a liver function tests for screening and 497 patients ranging from the age of 4 to 74 were chosen for the study. Patients with basal liver disease or DM were excluded during the screening process. Patients were classified into case(abnormal) and control(normal) groups by normal liver function test references. Results and Conclusions : In this study, Significant correlations for abnormal total bilirubin levels was age, for abnormal AST was gender, for abnormal ALT were gender, smoking, marriage status, and job, for abnormal ${\gamma}$GT were age, gender, obesity, alcohol, smoking, marriage status, and job using the Chi-square test(p<0.05). There was no significant correlations for abnormal LFTs by using herbal medication history, and intake duration. After controlling other covariates, logistic regression analysis showed that the significant associated factors for abnormal total bilirubin levels were age(odds ratio[OR]=0.87, 95% confidence intervals [CI]=0.87-0.99). For abnormal AST levels was obesity(OR=2.45, CI=1.2-4.9), for abnormal ALT levels were age(OR=1.01, CI=0.99-1.03), male gender(OR=3.31, CI=1.62-6.76), and obesity(OR=3.71 CI=2.28-6.08). For abnormal ${\gamma}$GT levels were male gender(OR=4.83 CI=1.34-17.43), obesity(OR=3.29, CI=1.74-6.22), alcohol (OR=2.51, CI=1.19-5.28), and smoking(OR=2.29, CI=1.16-4.50). Herbal medication history was not as a risk factor for all abnormal liver function tests. Therefore, people who are male, obese, alcohol drinker and smoker will have higher liver function test levels. But intake of herbal medication or the duration of intake may not be the risk factor for abnormal liver function test results.

금냉법(金冷法)에 대한 고찰 - 중국 논문을 중심으로 -

박해모 대한예방한의학회 2018 대한예방한의학회지 Vol.22 No.3

Objectives : ‘Geumnaeng method'’ is a well-known folk remedy, but It has not been studied in academia. This study was conducted to review the chinese published articles on Geumnaeg method (Jinleng method) of Chinese traditional medicine. Methods : The author searched Chinese published papers from 2000 to 2018 via CNKI(China National Knowledge Infrastructure) database by using keyword ‘Jinleng’, ‘Jinleng method’, and analyzed the papers covered Jinleng method health preservation, and classified them including periods, type of study, target symptoms, and comparison between countries. Results : 17 studies were reviewed. The study of Jinleng method in China began in 2005. 8 articles (47.1%) were review articles, 4 articles (23.5%) of the case report and case series, and 5 articles (29.4%) were clinical studies. Clinical studies have increased since 2008. Most of the studies related to genital disorders and sexual function were mainly performed. There were differences between Japan, Korea and China in Jinleng method. Conclusions : Various disease and symptoms was researched with Jinleng method in China. Research in China is more active than other country. We need to increase the level of evidence of Jinleng method’s effectiveness through additional studies in the future.

한약재내의 미량원소의 의의와 치료효과에 대한 고찰

박해모,이선동,Park Hae-Mo,Lee Sun-Dong 대한예방한의학회 2000 대한예방한의학회지 Vol.4 No.2

Trace element are involved in enzymatic activities, immunological reactions. physiological mechanisms. Deficiency in some trace elements, such as iron and iodine. is still an important health problem, The role of trace elements deficiency is suspected in various clinical situations and is now confirmed by well designed supplementation studies. However, the importance of trace elements as chinese herbal constituents is not sufficiently appreciated by the oriental medical profession, although in recent years a significant increase of new finding on their essential character in chinese herbal medicine occurred. It is well known that herbal medicine contains a variety of trace elements which would show therapeutic effects with active components in herbal medicine . In china, recent work showed some positive correlation between trace element and traditional chinese medicine (TCM) in terms of therapeutic effects even if their role in therapeutic effects is still obscure. In korea, not much attention has been on the therapeutic importance of trace element contained in herbal medicine Here, the therapeutic effects of trace element in TCM were reviewed and summarized. 1. Iron, copper, zinc and manganese are mainly contained in TCM. In addtion, chromium, magnesium, molybdenum, nickel, alminium, cobalt, arsenic and selenium has been studied for their therapeutic effects 2. Zinc, is decreased in patients who have deficiency of kindney(腎虛) and chronic disease. Fe is decreased in patients who have deficiency of blood(血虛). However copper is increased in patients who have chronic disease and hepatic disease.3 Iron concentration is high in herbs used for tonifying and nourishing yin or blood(補陰補血藥) Zinc concentration is high also in herb used for tonifying kidiney and vital essence(補腎補精藥). In addition. copper concentration Is high in herb used for replenishing qi(補氣藥) 4 In herbal drugs, the therapeutic substances in TCM are not only organic but also inorganic. It seems that trace elements would be one of components in herb for its therapeutic effects. This indicates that therapeutic effects of TCM should be extended not only to herb itself, bur also to trace elements contained in herb.

달생탕이 랫드의 모체와 태자에 미치는 영향에 대한 연구

박해모,김창석,이선동,이장우,유재홍,김판기,Park, Hae-Mo,Kim, Chang-Seok,Lee, Sun-Dong,Lee, Jang-Woo,Ryu, Jae-Hong,Kim, Pan-Gyi 한국환경보건학회 2006 한국환경보건학회지 Vol.32 No.4

The experiments was undertaken to evaluate the effects of herbal medicine, Dalsaengtang, in pregnant rats and fetuses. Female Sprague-Dawley rats were orally administered with the Dalsaengtang at dose of 5 mg/kg/day for 20 days. Pregnant rats were sacrificed at 20th day of gestation, and observed internal and reproductive organs. Approximately live fetuses in the 20th day of gestation were randomly selected and fixed in 95% ethanol. To observe skeletal malformations, fetuses were stained with alcian blue and alizarin red S. Maternal body weight of dalsaengtang treated group has a tendency to increase compared to that of control group. The relative liver and kidney weights of dalsaengtang treated group were also increased to that of control group. There were no significant changes between two groups in blood chemistry and hematological values. There were no significant changes in number of corpus luteum, implantation, live fetuses and implantation rate, delivery rate, late resorption rate and sex ratio. But Dalsaengtang administered group showed lower early resorption rate than the control group. From the sex ratio, number of females, bigger than number of males in the control group, and more males than females in Dalsaengtang administered group. Neonatal body weight and number of fetus of Dalsaengtang group were increased to that of control group. The fetuses of dams treated with Dalsaengtang didn't showed external malformation. Vertebral and sternal variations were observed in Dalsaengtang group but, compared to the control, those variations were insignificant. The number of ribs, cervical, thoracic, and lumber were normal. The number of sacral and caudal vertebrae were increased. Fetuses showed significant difference in the number of caudal vertebra (P<0.01). From these results, it can be concluded that Dalsaengtang showed no toxicity effects on maternal body weight, early resorption rate, and number of live fetuses. There were no significant changes in organ weight, hematological data, reproductive organs. Although skeletal variations were showed in vertebrate and sternum, Dalsaengtang did not shown significant changes in bone malformation.