Proteome Profile Changes during Transdifferentiation of NRP-152 Rat Prostatic Basal Epithelial Cells

박영일,Tag Keun Yoo,Jung Hye Shim,David Danielpour,Chung Lee,Yu Sam Kim 한국분자세포생물학회 2004 Molecules and cells Vol.17 No.1

셀레나움을 투여한 백서에 간에 있어 glutathione S - transferase 의 유도

박영일,정안식 ( Young Yil Bark,An Sik Chung ) 생화학분자생물학회 1989 BMB Reports Vol.22 No.1

The effect of sodium selenites (Na₂SeO₃, Se) on the activities of glutathione (GSH) S-transferase was examined. The treatment of rats with Se(5,10 and 20μmoles) caused dose-dependent increase in the activities of GSH S-transferases in male rats. Furthermore, repeated sodium selenite administration increased the activities of GSH S-transferases in male and female rats. GSH S-transferases are a dimer and composed of Ya, Yb (or Yb`) and Yc subunits. Se treatment elevated the relative amount of Yb (Yb`) subunits in both sexes. The increaments of Yb (Yb`) subunits were from 29.5% to 46.4% in male rats and from 4.8% to 9.3% in female rats. The separation of GSH S-transferases into basic and neutral/acidic ones was performed using the method of chromatofocusing. Six peaks of enzymes correspond to fractions of isozymes L₂, BL, B₂, A₂, AC and C₂ by the order of chromatofocusing elution. The administration of Se in male and female rats induced, basic transferases, A₂ and C₂ isozymes but not AC isozymes. C₂ isozyme increased 7.72 fold in males and 2.72 fold in females, and A₂ isozyme increased 1.56 fold and 2.04 fold, respectively. Selenium treatment also increased activity of neutral/acidic isozymes 1.37 fold in male but did not increased the activity of neutral/acidic isozymes in female. The significant differences between male and female rats by Se administration were C₂ isozymes and neutral/acidic GSH S-transferases.

An Aromatic lmine Group Enhances the EL Efficiency and Carrier Transport Properties of Highly Efficient Blue Emitter for OLEDs

박영일,이지훈,정동현,Chung Chihwu,박종욱 한국고분자학회 2010 한국고분자학회 학술대회 연구논문 초록집 Vol.2010 No.10

Induction of some Glutathione S-transferases in rat liver by selenium

박영일,정안식,Bark, Young-Yil,Chung, An-Sik 생화학분자생물학회 1989 한국생화학회지 Vol.22 No.1

소디움 셀레나이트 $Na_2SeO_3$를 쥐에 투여하였을 때 Glutathione S-transferase의 활성도에 미치는 영향을 조사했다. 셀레니움 농도를 각기 달리하여 5, 10 그리고 $20{\mu}mol$ 농도로 숫쥐에 주사했을 때, GSH S-transferase의 활성도는 투여된 셀레니움의 양에 따라 증가했으며, 반복해서 소량의 소디움 셀레나이트를 소량으로 계속 주사했을 시에 숫쥐와 암쥐에 있어 GSH S-transferase의 활성도가 또한 증가하였다. GSH S-transferase는 dimer이며, 그 단위는 Ya, Yb (또는 Yb') 그리고 Yc로 이루어져 한다. 셀레니움을 투여했을 때 암쥐, 숫쥐 모두 Yb(Yb') 단위가 증가했다. Yb 단위 증가량은 숫쥐의 경우 29.5%에서 46.4%, 암쥐의 경우 4.8%에서 9.3% 정도이다. GSH S-transferase의 분리는 Chromatofocusing 방법에 의해 분리했다. 염기성 효소의 여섯개 peak는 Chromatofocusing elution 순서에 의해 $L_2$, BL, $B_2$, $A_2$, AC와 $C_2$인 동위효소와 상응한다. 암쥐와 숫쥐에 셀레니움을 투여했을 때 염기성 transferase인 $A_2$와 $C_2$ 동위효소 (isozyme)는 유도되었으나 AC 동위효소 (isozyme)는 유도되지 않았다. $C_2$ 동위효소는 숫쥐의 경우 7.72배 증가했으며, 암쥐의 경우 2.72배 증가했다. 그리고 $A_2$ 동위효소는 숫쥐의 경우 1.56배 증가했으며, 암쥐의 경우 2.04배 증가했다. 또한 셀레니움 투여시 숫쥐의 경우 neutral/acidic 동위효소 1.37배 활성도가 증가했으나 암쥐의 경우 증가하지 않았다. 셀레니움 투여량에 의한 숫쥐와 암쥐간의 유의적인 차이점은 $C_2$ 동위효소와 neutral/acidic GSH S-transferase에서 나타냈다. The effect of sodium selenites ($Na_2SeO_3$, Se) on the activities of glutathione (GSH) S-transferase was examined. The treatment of rats with Se(5,10 and $20{\mu}moles$) caused dose-dependent increase in the activities of GSH S-transferases in male rats. Furthermore, repeated sodium selenite administration increased the activities of GSH S-transferases in male and female rats. GSH S-transferases are a dimer and composed of Ya, Yb (or Yb') and Yc subunits, Se treatment elevated the relative amount of Yb (Yb') subunits in both sexes. The increaments of Yb (Yb') subunits were from 29.5% to 46.4% in male rats and from 4.8% to 9.3% in female rats. The separation of GSH S-transferases into basic and neutral/acidic ones was performed using the method of chromatofocusing. Six peaks of enzymes correspond to fractions of isozymes $L_2$, BL, $B_2$, $A_2$, AC and $C_2$ by the order of chromatofocusing elution. The administration of Se in male and female rats induced, basic transferases, $A_2$ and $C_2$ isozymes but not AC isozymes. $C_2$ isozyme increased 7.72 fold in males and 2.72 fold in females, and $A_2$ isozyme increased 1.56 fold and 2.04 fold, respectively. Selenium treatment also increased activity of neutral/acidic isozymes 1.37 fold in male but did not increased the activity of neutral/acidic isozymes in female. The significant differences between male and female rats by Se administration were $C_2$ isozymes and neutraVacidic GSH S-transferases.

육용계에 있어 계종과 사양수준간의 상호작용에 관한 연구

박영일(Y . I . Park),배규한(G . H . Bae),정흥우(H . W . Chung) 한국축산학회 1987 한국축산학회지 Vol.29 No.6

Five different broiler stocks were compared under two kinds of feeding regimes with different levels of dietary protein and energy to study the interaction between stock and feeding regime. An experimental unit was composed of ten chicks and 6 units were allotted per feeding regime per stock. The traits studied were body weights at 2, 4, 6 and 8 weeks of age, shank length and keel length at 6 and 8 weeks and feed efficiency. viability and income per bird over the cost of day old chick and of feed for the period 0 - 6 weeks and 0 - 8 weeks. The differences among stocks were large and significant for most traits. The differences between the feeding regimes were statistically significant for body weights, keel length and feed efficiency. Males had larger body weights, longer shank and keel, better feed efficiency and higher gross income per bird than females. The interaction between stock and feeding regime was statistically not significant in all traits studied except the feed efficiency for 0-6 weeks and income per bird for 0-8 weeks. The interaction between stock and sex was statistically not significant except the body weights at 6 and 8 seeks. The significant interaction for the body weights appeared to be resulted from a smaller sex difference in certain stock compared with those in other stocks. The interaction between feeding regime and sex was statistically significant for none of the traits studied. The results obtained indicate that the interaction between stock and feeding regime is relatively unimportant for most traits examined in this study.

돼지에 있어 복당산자수와 복당포유개시자돈수의 유전력과 유전상관

정흥우,박영일 ( H . W . Chung,Y . I . Park ) 한국축산학회 1986 한국축산학회지 Vol.28 No.9

Data from 351 purebred Large White litters produced by 34 sires were utilized to obtain genetic and phenotypic parameter estimates for the total number of pigs born per litter, the number of pigs born alive per litter and the number of pigs suckled per litter. The heritabilities and genetic and phenotypic correlations were estimated from the sire components of variance and covariance. Heritabilities estimated in this study were 0.10±0.20 for the total number of pigs born per litter, 0.14±0.20 for the number of pigs born alive per litter .and 0.08±0.20 for the number of pigs suckled per litter. The genetic correlations of the total number of pigs born per litter with the number of pigs born alive per litter and the number of pigs suckled per litter were 1.18 and 0.75 respectively, and the genetic correlation between the number of pigs born alive per litter and the number of pigs suckled per litter was 0.83. Phenotypic correlations among the litter traits were highly positive.

New blue-violet emitters based on an indenopyrazine core for OLEDs

이하윤,박영일,김수강,이지훈,정동현,( Chung-chih Wu ),박종욱 한국공업화학회 2013 한국공업화학회 연구논문 초록집 Vol.2013 No.1

상향 두 파장 TDM-PON을 이용한 전송효율의 향상

정준회(Junhoi Chung),박재욱(Jaeuk Park),최병철(Byungchul Choi),유제훈(Jeahoon Yoo),김병휘(Byoung-Whi Kim),박영일(Youngil Park) 한국통신학회 2008 韓國通信學會論文誌 Vol.33 No.8B

TDM-PON의 상향전송 데이터 프레임은 여러 가지 오버헤드를 포함하고 있으며, 각 ONU 전송시간 사이에는 가드밴드가 존재한다. 이들은 수신단의 동기 및 전송성능 유지를 위해 중요한 요소들이지만, 상향 대역폭 낭비의 원인이 되고 있다. 본 논문에서는 상향 전송에 두 종류의 파장을 이용해 대역폭 이용효율을 극대화하는 방식의 TDM-PON을 제안하였다. ONU들에 두 파장을 고르게 배치하고, 각 ONU는 전송 패킷의 오버헤드를 중첩하여 전송함으로써 이용 효율을 100%에 근접하도록 하였으며, 이를 위한 OLT 다중화회로를 구현하였다. Upstream data frame of TDM-PON includes various types of overheads, and there exist guard bands between consecutive frames from different ONUs. Although they are indispensible in synchronization and performance, they cause bandwidth waste at the same time. To solve this problem, a new TDM-PON that uses two types of wavelengths in upstream transmission is suggested. By even distribution of two wavelengths among ONUs and overhead overlap between frames that use different wavelengths, almost 100% bandwidth efficiency could be achieved. A serializer that multiplexes signals from two wavelengths is implemented for this purpose.

돼지에 있어 성장율 , 등지방두께 , 체장 및 체고에 대한 유전모수의 추정

정흥우(H . W . Chung),박영일(Y . I . Park) 한국축산학회 1990 한국축산학회지 Vol.32 No.5

This study was conducted to estimate the heritabilities and genetic and phenotypic correlations among average daily gain, age at 90kg, backfat thickness, body length and wither`s height. The data used for this study were obtained from 5,386 heads of Duroc, Landrace and Yorkshire boars and gifts tested on a weightconstant basis at S Swine Breeding Farm at Icheon, Kyunggi Do from August, 1982 to August, 1987. The results obtained in this study are summarized as follows ; 1. The heritabilities of the traits estimated by sire variance component were 0.259±0.081 for average daily gain, 0.288±0.082 for age at 90kg, 0.409±0.100 for backfat thickness, 0.160±0.064 for body length and 0.201±0.062 for wither`s height, respectively. 2. The genetic correlations of average daily gain with age at 90kg, backfat thickness, body length and wither`s height were -0.765, -0.084, -0.202 and -0.081, respectively. The genetic correlations of age at 90kg with backfat thickness, body length and wither`s height were 0.127, 0.203 and 0.045 respectively. The genetic correlations of backfat thickness with body length and wither`s height were -0.202 and -0.216, respectively and the genetic correlation between body length and wither`s height was 0.334. 3. The phenotypic correlations of average daily gain with age at 90kg, backfat thickness, body length and wither`s height were -0.771, -0.102, -0.048 and-0.032, respectively. The phenotypic correlations of age at 90kg with backfat thickness, body length and wither`s height were 0.133, 0.037 and 0.033.. respectively. The phenotypic correlations of backfat thickness with body length and wither`s height were -0.144 and 0.158, respectively and the estimate of body length with wither`s height was 0.293 in phenotypic correlation.

돼지에 있어 일당증체량과 등지방두께에 대한 선발지수

권오섭,김성훈,정흥우,박영일 ( O . S . Kwon,S . H . Kim,H . W . Chung,Y . I . Park ) 한국축산학회 1986 한국축산학회지 Vol.28 No.10

Selection index for average daily gain and backfat thickness was derived from the genetic and phenotypic parameters estimated on the basis of the data from 3,369 heads of Yorkshires, Durocs, Hampshires and Landraces tested from March, 1984 to August, 1985. The results obtained in this study are summarized as follows; 1. The heritabilities of average daily gain estimated were 0.369, 0.470, 0.318 and 0.367, respectively, in Yorkshires, Durocs, Hampshires and Landraces and the average heritability was 0.381. The heritabilities of backfat thickness estimated were 0.404, 0.662, 0.565 and 0.892, respectively, in Yorkshires, Durocs, Hampshires and Landraces and the average heritability was 0.631. 2. The genetic correlations between average daily gain and backfat thickness were 0.238, 0.425, -0.132 and 0.079, respectively, in Yorkshires, Durocs, Hampshires and Landraces and the average genetic correlation was 0.152. The phenotypic correlations between average daily gain and backfat thickness, were 0.147, 0.321, 0.020 and 0.147, respectively, in Yorkshires, Durocs, Hampshires and Landraces and the average phenotypic correlation was 0.159. 3. The selection index derived from the estimated parameters and economic weights based on the data from market survey on the price of the products was I₁= =X₁+ 6.52X₂ and the index from the economic weights based on the regression analysis of the price of the breeding stocks was I₂= =X₁+ 2.94X₂. (X₁= backfat thickness(㎝), X₂=average daily gain(㎏))