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시야 결손이 있는 뇌하수체샘종 환자에서 수술 후 시야 변화
문찬희,황선철,박태관,Chan Hee Moon,Sun Chul Hwang,Tae Kwann Park 대한안과학회 2011 대한안과학회지 Vol.52 No.6
Purpose: To evaluate visual field (VF) changes in patients with pituitary adenoma after surgical treatment. Methods: The present study retrospectively evaluated 96 eyes of 48 patients with pituitary adenoma who received surgical tumor removal between July 2001 and February 2010. Preoperative and postoperative clinical data including age, tumor volume, logMAR BCVA, surgical technique (transsphenoidal surgery and transcranial surgery), static perimetry scores (mean deviation [MD], pattern standard deviation [PSD], and visual field defect [VFD] scores) were reviewed. Results: The MD (15.79%, p = 0.001) and PSD (3.98%, p = 0.003) improved postoperatively (mean postoperative follow- up period 1.85 months). Transsphenoidal surgery for tumor removal showed significant MD (26.99%, p = 0.000) and PSD (12.92%, p = 0.003) improvements. A multivariate regression analysis of the transsphenoidal surgery patient group revealed that the preoperative MD was related to the postoperative MD (Pearson = 0.762, p = 0.000), but negatively correlated to the amount of postoperative improvement in MD score (Pearson = -0.231, p = 0.046). Transcranial surgery did not significantly improve the MD (p = 0.419), PSD (p = 0.562), VFD score (p = 0.135), or logMAR BCVA (p = 0.708). Conclusions: Visual filed defects in patients with pituitary adenoma improved after neurosurgical treatment. Better postoperative visual field outcomes were achieved in patients who had smaller preoperative visual field defects. Transsphenoidal surgery significantly improved the visual field defects and visual acuity in patients with non-functioning pituitary adenoma, compared to the transcranial surgery patients. J Korean Ophthalmol Soc 2011;52(6):726-733
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문찬희,최경식,이미리,이성진,Chan Hee Moon,Kyung Seek Choi,Mi Ri Rhee,Sung Jin Lee 대한안과학회 2013 대한안과학회지 Vol.54 No.1
Purpose: To assess the influence of body position on intraocular pressure (IOP) in patients who underwent vitrectomy and intraocular gas tamponade. Methods: Patients who did not undergo any surgery were defined as Group 1. The remaining patients were divided into 3 groups according to the surgery performed (Group 2; cataract surgery, Group 3; vitrectomy and cataract surgery, Group 4; vitrectomy with intraocular gas tamponade and cataract surgery). IOP was measured by a non-contact tonometer, Goldmann applanation tonometer, and Tono-Pen in the sitting, supine, and prone positions. Results: The difference of IOP measured in the sitting position among the 4 groups was not significant. IOP was significantly elevated by 2.04 mm Hg on average when the posture was changed from sitting to supine or prone in all 4 groups. The IOP discrepancy between supine and sitting positions was significantly greater in group 4 by 3.61 mm Hg than the other groups (p = 0.003, ANOVA test). The IOP difference between the prone and sitting position was also significantly higher in group 4 by 3.82 mm Hg than the other groups (p = 0.001, ANOVA test). Conclusions: The patients with vitrectomized gas tamponade eyes had a mean IOP increase of 3.82 mm Hg when the position was changed from sitting to prone. When performing vitrectomy and intraocular gas tamponade on patients in the prone position, an IOP elevation should be monitored thoroughly.
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문찬희,김소영,Chan Hee Moon,MD,So Young Kim,MD,PhD 대한안과학회 2012 대한안과학회지 Vol.53 No.7
Purpose: To report a case of ocular myasthenia gravis in conjunction with thyroid-associated ophthalmopathy in a patient who showed incomitant strabismus and blepharoptosis as well as to discuss the clinical features and tests that may help distinguish these 2 diseases. Case summary: A 46-year-old man without any previous history of systemic and ophthalmic disease presented with binocular diplopia that occured a month earlier. The patient had no other systemic symptoms except a 7 kg weight loss within the last month. The patient was referred to the department of internal medicine and brain magnetic resonance imaging was performed to ascertain the cause of suspected left superior oblique muscle palsy. The patient was diagnosed with Graves’ disease and underwent medical treatment. One month later, the patient presented with consistent diplopia and exophthalmos and showed a swelling of eyelid and ptosis in the right eye. Intravenous high-dose steroid therapy was administered to the patient. After the treatment, symptoms of diplopia and lid swelling were improved, however ptosis persisted. Ocular myasthenia gravis was suspected and various tests were conducted. Anti-acetylcholine receptor antibodies were detected in large amounts and ptosis was improved dramatically by an administration of an anticholinesterase agent. The patient was diagnosed with ocular myasthenia gravis in conjunction with thyroid-associated ophthalmopathy. Conclusions: Ocular myasthenia gravis should be suspected in patients with thyroid-associated ophthalmopathy who have signs or symptoms of ptosis. J Korean Ophthalmol Soc 2012;53(7):1057-1061
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김영훈,박영숙,문영수,김혜랑,이정돈,한준길,문찬희,황인후,황의경,김은경,주종은 대한소화기학회 1999 대한소화기학회지 Vol.33 No.3
Mucosa-associated lymphoid tissue (MALT) lymphoma is a low grade B cell lymphoma which de velops in MALT. The authors report a case of MALT lymphoma in cecum and ascending colon in a 37-year-old male. He recognized palpable mass and tenderness on right lower abdomen 3 days before admission. At his first admission, he was misdiagnosed as actinomycosis in colon and penicillin G was administered. Four weeks later, he revisited our hospital because of colonic mecha nical obstruction. Subsequently, right hemicolectomy was performed. Macroscopically, infiltrating tumor from terminal ileum to ascending colon was found. Microscopic findings showed glandular mucosa with atypical lymphocytes, lymphoepithelial lesion (LEL) formed by centrocyte-like (CCL) cell invasion of epithelium lining gland, plasmacytoid differentiation and positive B cell marker in immunohistochemical stain. A histological and immunohistochemical study revealed it to be a lowgrade B cell lymphomas of MALT type.
KCI
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