몽테뉴의 죽음관에 대한 고릴라의 고찰 : 마요르가의 『눈송이의 유언』

김재선 ( Jae Seon Kim ),박채연 ( Chae Yeon Park ) 韓國世界文學比較學會 2012 世界文學比較硏究 Vol.38 No.-

Dentro del teatro espanol contemporaneo, los dramaturgos espanoles, nacidos en los anos 60 y caracterizados principalmente por escribir una vez normalizada la vida democratica del pais, han ido ocupando de manera progresiva un lugar de relieve. Perteneciendo generalmente al ambito de la llamada escena alternativa, muchas de sus propuestas dramaticas, de los lenguajes empleados y de los temas que abordan en sus textos revelan la vitalidad y el interes de este grupo de autores. Sin duda, las obras de Juan Mayorga(1965, Madrid) conforman una de las trayectorias mas interesantes de la dramaturgia espanola contemporanea, en las que se han representado varios de sus textos tanto en teatros publicos, como en teatros semipublicos y en teatros de tendencia comercial o alternativa, incluido algun espacio dedicado a albergar actividades ajenas al teatro. Himmelweg, Animales nocturnos(2003), Ultimas palabras de Copito de Nieve(2004), Hamelin(2005), El chico de la ultima fila(2006), La tortuga de Darwin, La paz perpetua(2008). Es un autor de solida formacion, tanto en filosofia como en matematicas. Se inicia en el teatro tras recibir varios cursillos y practica un tipo de escritura original y llena de sugerencias. Ultimas palabras de Copito de Nieve de Juan Mayorga trata del gorila blanco del zoologico de Barcelona que murio en 2003. Por la imaginacion teatral del autor, Copito de Nieve se nos muestra como un gorila filosofo y se ha convertido en especialista de Montaigne. Segun Montaigne, filosofar es aprender a morir y Copito concluyo que no hay razon para tenerle miedo. "Vivid como si fueseis a morir hoy mismo. El que sabe morir, sabe vivir. La muerte es la autentica libertad..." Sus palabras son las que tienen mucho que aprender los humanos. Mayorga tambien plantea su critica hacia la hipocresia con que se establecen muchas relaciones sociales, obligando a portarse como quieren los demas. El final parece inminente. Es el momento de dejar de fingir y quitarse la mascara.

한국교회 공동체의 신정론: 분열의 아름다움과 악

김재선(Jae-Seon Kim) 연세대학교 신과대학(연합신학대학원) 2023 신학논단 Vol.111 No.-

저용량 Amoxicillin , Metronidazole , Omeprazole 병합투여에 의한 소화성궤양의 치료

김재선(Jae Seon Kim),박영태(Young Tae Bak),김진호(Jin Ho Kim),김종극(Jong Guk Kim) 대한소화기학회 1997 대한소화기학회지 Vol.29 No.3

N/A Background/Aims: Anti-Helicobacter pylori(H. pylori) therapies with few side effects are needed. We studied the effectiveness of low dose combination of amoxicillin, metronidazole, and omeprazole for treatment of ulcer patients. Methods: Patients with gastric or duodenal ulcer received amoxicillin(500 mg b.I.d.), metronidazole(125 mg b.I.d.), aod omeprazole(20 mg at bedtime) for 2 weeks. Endoscopic examinations were perforrned before treatment and at 4 weeks, 3 months, 6 months, 9 months and 1 year after ending antimicrobial therapy. H. pylori status was confirmed by CLO test. Results: 91 patients(72 men and 19 women) with a mean age of 45.2 years(range 19-81) were enrolled. There were 54 Dus, 32 Gus, and 5 with both. At 2 weeks, the compliance rate was 100%, and no side effects was noted. Of 69 patients(40 Dus, 25 Gus, and 4 with both) who had undergone endoscopy at 4 weeks after ending antimicrobial therapy, the ulcer healed in 55 patients(34 Dus, 19 Gus, and 2 with both), and H. pylori infection was cured in 49 patients(27 Dus, 19 Gus, and 3 with both). And so the healing rate of ulcer and cure rate of H, pylori at 4 weeks after ending antimicrobial therapy was 79.7%(DU 85.0%, GU 76.0%, and Both 50%) and 71.0%(DU 67.5%, GU 76.0%, Both 75%) respectively. 28(18 Dus, 9 Gus, and 1 Both) of the healed ulcer patients in whom H. pylori had been cured had been followed respectively up for 1 year; ulcer recurrence and H. pylori reoccurrence were 2(1 DU, 1 GU) and 3(1 DU, 2 Gus), thus ulcer recurrence and H. pylori reoccurrence was 7.1% and 10.7%, respectively. 8 patients(7 Dus, 1 GU) of the healed ulcer patients in whom H. pylori had not been cured were followed up during 1 year; there were 6 ulcer recurrences(6 Dus), and so ulcer recurrence was 75.0%, but natural eradication of H. pylori was not. Conclusions: The combination of amoxicillin, metronidazole, and omeprazole even at the low dose prescribed may be one of an effective therapy regimen with excellent compliance rate for peptic ulce.r. (Korean J Gastroenterol 1997;29:301 - 309)

흄의 정치적 의무론에 관한 연구

김재선(Kim Jae-Seon) 한국정치학회 1999 한국정치학회보 Vol.32 No.4

본 논문은 흄의 정치적 의무론을 자발주의 의무론의 고전적인 패러다임이라고 할 수 있는 사회계약론을 비판하면서 그 대안으로 제시된 최초의 ‘목적론적 의무론’의 모델로 규정해서 이해하려고 했다. 이에따라 흄의 의무론은 (1) “의무는 ‘권리’나 ‘정의’ 개념들과 같이 인간의 인위적 고안물이다” (2) “의무는 약속으로부터 자연적으로 발생치 않는다. 모든 도덕성은 감정에 기초하며, 의무 역시 의무 감정이 선행해야 한다” (3) “약속은 사회의 필요성과 이익에 기초한 인간의 고안물이다” 등과 같은 핵심 명제에 기초하고 있음을 알 수 있다. 아울러 흄의 의무론이 기초하는 도덕적 정당화의 토대는 (1) ‘유용성(Utility)’ 차원과 (2) ‘관습(Convention)’ 차원에서 제공되고 있음을 알 수 있다. 끝으로 흄의 의무론 속에는 수혜의 제공자로서의 국가에 대해 수혜자로서의 시민이 지니는 ‘정치적 복종’의 문제가 중점적으로 다뤄지고 있다. 그러나 동시에 국가와 시민 간의 수혜관계가 약화 또는 소멸될 때 제기될 수 있는 ‘정치적 불복종’의 문제 역시 중요하게 논의되고 있음을 알 수 있다.

하부대장 과형성 용종의 의의

김종극(Jong Guk Kim),이창홍(Chang Hong Lee),박영태(Young Tae Bak),김진호(Jin Ho Kim),김재선(Jae Seon Kim),변관수(Kwan Soo byun),지종대(Jong Dae Ji),송훤택(Hwun Taig Song) 대한소화기학회 1993 대한소화기학회지 Vol.25 No.4

N/A Adenomatous polyps are known to be precursors for cancer, and identifying of persons with adenomatous polyps is practically important because these individuals should constitute a disproportionate percentage of persons destined to have colorectal cancer. There is enough reason to believe that regclar endoscopic screening of persons with adenomatous polyps and removal of these polyps can reduce the incidence of colorectal cancer. But hyperplastic colonic polyps are generally regarded as being of little or no clinical consequence. Recentlyl, however, controversy has not been settled down on the significance of distal colonic hyperplastic polyp as a marker for proximal colonic adenomatous polyp (s). To establish the prevalence of proximal neoplasms in subjects with or without hyperplastic polyps in distal colon and to determine whether the presence of hypcrplastic polyps in the distal colon could serve as a market for proximal synchronous adenomatous colonic polyps, we prospectively analyzed 895 consecutive subjects who were examined with colcnoscopy between March 1990 and October l992. 191 of 895 subjects (21.4%) had one or more colonic polyps. The prevalence of adenomatous polyps alone was 10.2% hyperplastic polyps 8.4%, and both 1.9%. The proportion of subjects with both proximal adenomatous polyp and distal hyperplastic polyps (6.0%) was not significantly different from the proportion of those without distal hyperplistic polyps(5.1%), But subjects with distal adenomatous polyps (s) were si!nificantly more likely to have proximal adenomatous polyp (s) than those without distal adenomatous polyp (s). The result of this study suggests that hyperplastir. polyps of distal colon do not serve as a marker for neoplastic polyps of proximai colon.

산화질소가 Guinea Pig 의 Oddi 괄약근 운동에 미치는 영향에 관한 연구

김재선(Jae Seon Kim),현진해(Jin Hai Hyun),박영태(Young Tae Bak),김창덕(Chang Duck Kim) 대한내과학회 1996 대한내과학회지 Vol.50 No.1

N/A Objectives: Recent studies indicate that intric oxide (NO) is a novel inhibitory neurotransmitter involved in several functions of many gastrointestianl organs. But only a few studies regarding its effect on sphincter of Oddi (SO) function were done until now. The aims of this study were to determine the effect of NO on motility of SO in L-arginine, a substrate of NO, inhibits SO motility, if NO is an important transmitter controlling the motility of SO. Methods: After laparotomy, a pressure-monitoring perfusion catheter was introduced into the lumen of SO through common bile duct and another catheter into the 2nd portion of duedenum through low body of stomach, and tonic pressure and phasic contractions of SO were monitored with TDS 8000 Manometry System(Sandhill Scientific, USA) during baseline period and after infusing a specific NO synthase inhibitor, N-nitro-L-arginine(Sigma: L-NNA, 5 mg/kg body weight), and cholecystokinin-8(Squibb: CCk, 25 or 50pmol/kg body weight). Results: 1) Tonic pressure and phasic contractions were significantly increased after administration of the NO synthase inhibitor. The response to CCk was enhanced by the NO synthase inhibitor. 2) Addigion of the substrate of NO suppressed the NO synthase inhibitor-induced increase of the tonic pressure and phasic contractions, and also suppressed the NO synthase inhibitor-induced enhancement of the response to CCK. 3) Administration of only NO substrate did not significantly change the tonic pressure and phasic contractions of resting stage and the response to CCK. Conclusion: These findings suggest that NO is an important neurotransmitter that is responsible for the inhibitory neural regulation of the SO motility. But the administration of the substrate of NO, L-arginine, alone does not seem to be useful for the management of SO dysfunction

내시경 검사시 Phenol Red 분무에 의한 Helicobacter pylori 감염 진단의 의의

김종극(Jong Guk Kim),이창홍(Chang Hong Lee),박영태(Young Tae Bak),김진호(Jin Ho Kim),원남희(Nam Hee Won),김재선(Jae Seon Kim),변관수(Kwan Soo byun) 대한소화기학회 1993 대한소화기학회지 Vol.25 No.1

N/A A strong association between Helicobacter pylori (H. pylori) and chronic active inflammation of the gastric antrum and duodenal ulceration has been recognized. Although various rnethods have been proposed to detect this microorganism, no unanimity exists among investigators concerning which method represents a gold standard. H. pylori producee urease that converts urea to ammonia which then raises the pH, therefore we have utilized an endoscopic spray technique using phenol red (pH indicator) in vivo to assess H. pylori infection itself and its distribution. 87 patients with dyspepsia were pre-medicated with ranitidine 150 mg p.o. 3 houre before endoscopy to maintain a gastric pH between 3-6. During endoscopy, 20 ml of a mixture containing 0.05% phenol red and 0.5% urea was sprayed over the antral mucosa using a spray catheter. It was defined as positivc if any area of the mucosa turned red within 3 min after spraying. Antral biopsies were taken from all patients. Biopsies were assessed in a blind fashion after H&E, Giemsa and Warthin-Starry silver stain. The phenol red positive patients were 54.0%, and diffuse pattern of positive staining was 85.1% and regional pattern was 14.9%. Diagnostic sensitivity and specificity of the endoscoic spray technique were 87.2%. and 85.0% respectively. In conclusion, the endoscopic phenol red spray technique may be one of the simple and useful screening tests for diagnosis of H. pylori infection and for dilineating its probahle pattern of distributionvn gastric mucosa in vivo, but this method seems not useful for confirmatory diagnosis of H. pylori infection and needs further study.

목향(木香)이 고지방 식이에 의한 비만으로 유발된 인슐린 저항성 mouse의 염증 및 인슐린 저항성에 미치는 영향

오재선,마영훈,최승범,김종호,김경국,전상윤,Oh, Jae-Seon,Ma, Young-Hun,Choi, Seung-Bum,Kim, Jong-Ho,Kim, Kyung-Kook,Jeon, Sang-Yun 대한한방내과학회 2014 大韓韓方內科學會誌 Vol.35 No.4

Objectives: Obesity is an important cause of insulin resistance that leads to obese type 2 diabetes. Recently it has been found that obesity is associated with adipose tissue accumulation which causes systemic inflammation. In this study, we investigated effects of Inula helenium on the inflammation in high fat diet-induced insulin resistance mouse. Methods: Insulin resistance was induced in C57BL/6 male mice (19~21 g) on a 60% fat diet. Mice were divided into 3 groups (n=6) of normal, control and Inula helenium. After 12 weeks, body weight, FBS, oral glucose tolerance test (OGTT), serum level of insulin, epididymal fat pad, liver weight and the gene expression of tumor necrosis factor (TNF)-${\alpha}$, interleukin (IL)-6, interleukin (IL)-10 and cluster of differentiation (CD) 68 were measured. Also, adipose tissue macrophage was analyzed by fluorescence activated cell sorting. Results: Inula helenium significantly reduces oral glucose tolerance levels, insulin serum level and adipose tissue macrophage. Also Inula helenium increased IL-10 gene expression and decreased CD68 gene expression. Conclusions: These results show that Inula helenium has anti-insulin resistance and anti-inflammatory effects on a high fat diet-induced insulin resistance mouse model.

불안정성 대퇴 전자간 골절에서 전내측 피질골 중첩에 의한 정복

김채근 ( Chae Geun Kim ),권석현 ( Suc Hyun Kweon ),한홍준 ( Hong Jun Han ),황재선 ( Jae Seon Hwang ) 대한고관절학회 2013 Hip and Pelvis Vol.25 No.4

목적: 불안정성 대퇴 전자간부 골절 치료에서 골절의 원위부를 외측 전위시켜 전내측 피질골을 중첩 시키는 방법으로 정복 후 치료 결과에 대해서 알아보고자 하였다. 대상 및 방법: 2011년 8월부터 2012년 8월까지 불안정성 대퇴 전자간부 골절로 진단 받고 감마-3 정을 이용하여 치료한 후 최소 1년 이상 추시가 가능하였던 20예를 대상으로 하였다. 방사선학적 평가는 수술 후 및 최종 추시의 방사선 검사를 통하여 NSA, TAD, Cleveland index, 지연 나사의 활강 정도, 골유합 시기를 측정하였다. 골절 정복의 정도는 Baumgaertner 기준 변형된 방법을 따라 양호(good), 적당(acceptable), 불량(poor)로 분류하였다. 결과: 대퇴 경간각은 수술 후 평균 140。였으며, 최종 추시상 평균 135。로 감소되었다. TAD는 평균 11.3 mm였으며, 지연 나사의 위치는 정중앙에 12예, 중앙 하부에 8예가 위치하였다. 최종 추시시 지연 나사 활강 거리는 평균 5.5 mm였다. 평균 골유합 기간은 3.7개월이었으며, 수술 직후 골절의 정복 상태는 양호 15예, 적당 5예로 전예에서 만족할만한 정복을 얻었다. 최종 추시상 정복 소실 및 지연 나사의 골두 관통(cut out) 등의 고정실패 및 다른 합병증은 발생하지 않았다. 결론: 불안정성 대퇴 전자간부 골절 치료에서 골절의 원위부를 외측 전위시키고, 전내측 피질골 근위부를 중첩(overlap) 시키고, 전후면상 외반 정복, 측면상 전방 전위 각형성 정복은 정복 소실 및 지연 나사의 골두 관통 등의 고정실패를 줄일 수 있는 방법이라고 사료된다. Purpose: The purpose of this article is to evaluate the result of treatment of unstable intertrochanteric fractures by lateralization of distal fragment and antero-medial cortex contact of the distal shaft piece. Materials and Methods: We conducted an analysis of 20 cases of unstable intertrochanteric fractures treated using a gamma-3 nail from August 2011 to August 2012 and followed up for more than one year. Using postoperative and last follow-up radiographs, we measured NSA, TAD, Cleveland index, sliding length of the lag screw, and union time. Adequacy of reduction was assessed by a modification in the criteria of Baumgaertner and classified as good, acceptable, or poor. Results: The mean NSA was 140。postoperative and 135。at last follow-up. The mean TAD was 11.3 mm. The position of the lag screw was in center-center in 12 cases, center-inferior in eight cases. The mean distance of lag screw sliding was 5.5 mm at last follow-up. The mean union time was 3.7 months. The state of reduction postoperatively was good in 15 cases, and acceptable in five cases. There was no failure of reduction, lag screw cut-out, or other complications at last follow-up. Conclusion: The reduction method for lateralization of distal fragment and antero-medial cortex contact of the distal shaft piece in an unstable intertrochanteric fracture is very useful for prevention of collapse of the fracture site, lag screw cut-out, and mechanical failure.

광증폭기 응용을 위한 Er 첨가 실리카 유리 박막의 제조

김재선,신동욱,정선태,송영휘,Kim, Jae-Seon,Sin, Dong-Uk,Jeong, Seon-Tae,Song, Yeong-Hwi 한국재료학회 2001 한국재료학회지 Vol.11 No.5

집적형 광증폭기는 대량생산이 용이하고. 단일 칩에 다기능의 광소자를 집적할 수 있다는 장점 때문에 활히 연구되어져 왔다. 본 연구에서는 수동형 집적광소자의 제작에 사용되는 화염가수분해증착법 (FHD)을 이용하여 실리콘 (Si) /실리카 ($SiO_2$) 광도파막을 제작하고, 이 박막에 Solution Doping 법을 이용하여 $Er^{3+}$ 를 첨가하여 광증폭 매질을 제작하는 연구를 수행하였다. There have been many investigations and researches on PLC type of optical amplifiers because they are convenient for mass production and also can integrate multi-functional devices into a single chip. In this research. the fabrication of optical waveguide made of Si/$Sio_2$ by FHD(Flame Hydrolysis Deposition) for passive integrated optical devices and $1.5\mu\textrm{m}$ optical amplifier by Solution Doping method, which is one of the method doping $Er^{3+}$ into the thin film, are mainly discussed.