조현병 환자들의 일상적 의사결정 과정에서 무쾌감증 및 자아존중감의 영향

김수정,김민경,홍연주,이선구,김재진,Kim, Soo-Jeong,Kim, Min-Kyeong,Hong, Yeon-Ju,Lee, Seon-Koo,Kim, Jae-Jin 대한생물정신의학회 2017 생물정신의학 Vol.24 No.3

Objectives Decision-making in patients with schizophrenia has been known to be inefficient in both cognitive and affective aspects. The purpose of this study was to investigate the influence of anhedonia and self-esteem on the decision-making process in schizophrenia. Methods Twenty patients with schizophrenia and 21 healthy controls performed the 'apparel purchase decision-making task', during which they were asked to respond to the preference, fitness, and price suitability, before making the final purchase decision. Generalized estimating equation and correlation analysis were conducted to explore for the difference of decision making patterns and influential factors between the two groups. Results The patients showed lower odds ratio (OR) of the fitness on the apparel purchase decision than the controls [OR 0.190 ; 95% confidence interval (CI) 0.047-0.762, p = 0.019). In the patient group, there was no correlation between the number of purchased trials and the severity of anhedonia, but the number of purchased trials was negatively correlated with the Rosenberg Self-Esteem Scale score at a trend level (R = -0.436, p = 0.055). Conclusions Patients with schizophrenia considered the fitness of clothes less than healthy controls on apparel purchasing decisions. Schizophrenia patients with lower self-esteem were intended to buy more clothes.

경기도 일개 지역사회 대표집단에서 고호모시스테인혈증의 유병률 및 관련요인에 대한 단면조사연구

김수정,임경숙,송미숙,강연지,이순영,Kim, Soo-Jeong,Lim, Kyung-Sook,Song, Mi-Sook,Kang, Yeon-Ji,Lee, Soon-Young 대한예방의학회 2009 예방의학회지 Vol.42 No.5

Background : Many previous studies have shown that elevated homocysteine in the serum is a well known risk factor for cardiovascular disease and this is associated with other risk factors for cardiovascular disease, but any Korean data on this is limited. Objectives : This study aimed to calculate the prevalence of hyperhomocysteinemia and to analyze the relation between elevated homocysteine and the lifestyle factors of Korean adults. Methods : We conducted a cross-sectional survey that included 650 men and 743 women (age range, 20 to 79 years) who were residents of Gwangju City in Gyeonggi-do. These subjects participated in the health interview and examination survey from November to December 2005. The total homocysteine, total cholesterol, HDL-cholesterol, LDL-cholesterol, and triglyceride in the serum were measured. All the participants had their body composition measured such as height and weight, and we obtained health-related behavioral information through the self-entry questionnaire. Results : Very right-handed skewed distributions of homocysteine were shown in men and women. The prevalence of hyperhomocysteinemia was 22.6% in men and 13.7% in women in Gwangju city. On the multiple logistic regression analysis, hyperhomocysteinemia was associated with age (OR=1.02, 95% CI=1.01-1.04), male gender (OR=1.60, 95% CI=1.02-2.52), severe general physical activity (OR=0.32, 95% CI=0.15-0.69) and nutrient consumption (OR=0.49, 95% CI=0.31-0.76). Conclusions : There is a great prevalence of hyperhomocysteinemia in adults of Gwangju City, Korea and it was associated with both genetic factors and lifestyle risk factors. This study can suggest that comprehensive lifestyle modification is needed in order to diminish the prevalence of hyperhomocysteinemia and to prevent CVD.

Porphyromonas gingivalis에 대한 노각나무 잎 추출물의 항균활성 및 생물막 형성 억제 효과

김혜수(Hye Soo Kim),박민정(Min Jeong Park),김수정(Soo Jeong Kim),김부경(Bu Kyung Kim),박준호(JunHo Park),김대현(DaeHyun Kim),조수정(Soo Jeong Cho) 한국생명과학회 2021 생명과학회지 Vol.31 No.3

본 연구에서는 천연물유래 구강건강 개선소재로써 노각나무의 이용 가능성을 알아보기 위해 노각나무 잎과 줄기를 에탄올에 추출한 다음 구강미생물에 대한 추출물의 항균활성을 조사하였다. 노각나무 잎과 줄기 추출물(1 mg/disc)은 구강미생물 중 P. gingivalis KCTC5352에 대해서만 항균활성을 나타내었으며 줄기보다는 잎 추출물의 항균활성이 우수하였다. 시판되고 있는 구강케어제품에 사용되고 있는 항균제와 노각나무 잎 추출물의 항균활성을 비교한 결과, P. gingivalis에 대한 노각나무 잎 추출물과 양성대조구로 사용한 triclosan의 항균활성은 유사하게 나타났으며. P. gingivalis에 대한 노각나무 잎 추출물의 MIC는 0.4 mg/ml이고 정균작용을 하였다. 노각나무 잎 추출물이 0.2-2.0 mg/ml 농도로 처리된 배양액에서 P. gingivalis KCTC5352의 생물막 형성과 세균 생육은 추출물의 농도가 증가할수록 농도의존적으로 억제되는 경향을 보였다. 또한 노각나무 잎 추출물(1 mg/ml) 처리가 P. gingivalis의 생물막 형성에 미치는 영향을 주사전자현미경으로 관찰한 결과에 의하면 추출물을 처리하지 않은 대조구는 추출물 처리구에 비해 P. gingivalis가 군집을 이루며 모여 있었고 세포 주변에서 생물막이 관찰되었지만 추출물을 처리한 처리구의 세포 주변에서는 생물막을 관찰할 수 없었다. qRT-PCR을 이용하여 생물막 형성 초기 과정에서 치면 부착에 필수적인 섬모(fimbriae)관련 mRNA 발현 양상을 0조사한 결과, 노각나무 잎 추출물이 0.2-2.0 mg/ml의 농도로 처리된 배양액에서 fimA와 mfa1 유전자 발현은 추출물의 농도가 높아질수록 농도의존적으로 억제되는 것을 확인할 수 있었다. 이상의 결과를 종합하면 노각나무 잎 추출물은 치주질환 원인균인 P. gingivalis에 대한 항균 활성과 생물막 형성 억제능이 우수하기 때문에 천연물유래 구강건강 개선소재로써 이용 가능성이 높을 것으로 판단된다. This study was conducted to investigate the potential of Stewartia koreana as oral healthcare materials. The antibacterial activity of ethanol extracts from leaves and branches of S. koreana against oral bacteria was confirmed. The leaf and branch extracts (1 mg/disc) showed antibacterial activity against P. gingivalis only among several tested oral bacteria. The leaf extracts showed higher antibacterial activity, with values similar to those of chlorhexidine, which was used as a positive control. The MIC of the leaf extract against P. gingivalis was 0.4 mg/ml and showed bacteriostatic action. The inhibitory effects of the extract on biofilm formation and on gene expression related to biofilm formation by P. gingivalis were determined by biofilm biomass staining, scanning electron microscopy (SEM), and qRT-PCR analysis. The biofilm production rate and cell growth of P. gingivalis in the cultures treated with 0.2-2.0 mg/ml of S. koreana leaf extracts were significantly decreased in a concentration-dependent manner. The inhibitory effect on the formation of P. gingivalis biofilms at concentrations of 1 mg/ml was confirmed by SEM. The qRT-PCR analysis showed concentration-dependent suppression of the fimA and fimB gene expression associated with fimbriae formation in the cultures treated with 0.2-2.0 mg/ml S. koreana leaf extract. These results support the conclusion that S. koreana leaf extracts can be used as oral healthcare materials derived from natural materials, as demonstrated by the antibacterial action and inhibition of biofilm formation of P. gingivalis.

노각나무 잎과 가지 추출물의 항산화 효과

김혜수(Hye Soo Kim),박민정(Min Jeong Park),김수정(Soo Jeong Kim),김부경(Bu Kyung Kim),박준호(JunHo Park),김대현(DaeHyun Kim),조수정(Soo Jeong Cho) 한국생명과학회 2021 생명과학회지 Vol.31 No.2

본 연구에서는 우리나라 고유 수종인 노각나무(Stewartia koreana)의 부위별 이용 가능성을 알아보기 위하여 노각나무 잎과 가지를 70% 에탄올에 침지한 다음 부위별 항산화 활성을 조사하였다. 노각나무 가지 추출물(53.18±0.2 mg GAEs/extract g)에 비해 잎 추출물(162.57±0.9 mg GAEs/extract g)의 총 폴리페놀 함량이 높게 나타났고 플라보노이드 함량도 가지(4.7±0.1 mg QEs/extract g)에 비해 잎(59.1±0.9 mg QEs/extract g)에서 높게 나타났다. 노각나무 추출물의 DPPH 라디칼 소거능과 ABTS 라디칼 소거 활성은 잎과 가지 모두 농도 의존적으로 증가하였으며 가지보다는 잎에서 높게 나타났다. 노각나무 추출물 0.4 mg/ml의 농도에서 잎과 가지의 DPPH 라디칼 소거능은 각각 91.85±0.01%, 29.93±0.2%였으며 노각나무 잎 추출물은 양성대조구로 사용한 ascorbic acid (1mg/ml, 93.71±0.1%) 보다 낮은 농도에서 ascorbic acid와 유사한 DPPH 라디칼 소거능을 나타내었다. 노각나무추출물 0.4 mg/ml의 농도에서 잎과 가지의 ABTS 라디칼 소거능은 각각 94.77±0.34%, 25.13±0.15%였다. 노각나무잎과 가지의 ORAC 지수는 각각 104.13±0.48 μM TEs/ extract g과 57.36±0.35 μM TEs/extract g으로 가지보다는 잎의 ORAC 지수가 더 높게 나타났다. 노각나무 추출물의 세포 독성은 WST-1 assay를 이용하여 추출물이 섬유아세포 CCD-986sk에 미치는 영향으로 평가하였다. 이상의 결과를 종합해보면, 노각나무 잎 추출물은 가지에 비해 항산화 활성 지표인 총 폴리페놀과 플라보노이드 함량이 높고 항산화 활성이 높기 때문에 노각나무 잎 추출물은 항산화 활성이 우수한 기능성 식의약품소재나 화장품 소재로 사용될 수 있을 것으로 판단된다. This study was carried out to evaluate the antioxidant properties of the dried leaves and branches of Stewartia koreana Nakai. The dried leaf and branch of S. koreana were extracted with 70% ethanol at 80℃. The antioxidant activities of ethanol extracts of S. koreana leaf (EESL) and S. koreana branch (EESB) were analyzed. The total polyphenol contents in EESL and EESB were 162.57±0.9 mg of GAEs/extract g and 59.1±0.9 mg of GAEs/extract g, respectively. The flavonoid contents in EESL and EESB were 59.1±0.9 mg of QEs/extract g and 4.7±0.1 mg of QEs/extract g, respectively. EESL showed a better scavenging ability with DPPH and ABTS than EESB, at 0.4 mg/ml. Moreover, EESL were more effective according to ORAC values than EESL. The toxicity of EESL was investigated using a WST-1 assay on the human skin fibroblast cell line CCD-986sk. Therefore, EESL can be used as a potential source of functional, naturally-sourced material in cosmetics as well as food.

임의후견에서 본인의 자기결정권과 법원의 감독

김수정(Kim Soo Jeong) 한국가족법학회 2017 가족법연구 Vol.31 No.2

From the perspective of autonomy the importance of lasting power of attorney (contractual guardianship) as an alternative to judicial guardianship is more and more emphasized. But the characteristic of lasting power of attorney, i.e guaranteeing the autonomy of disabled adults and the abstention of supervision could lead to abuse of authority by guardian. For the courts, there are two ways to protect adult from abuse of authority by contractual guardian: To control the opening of lasting power of attorney ex ante and to supervise the management of affairs by the guardian after the lasting power of attorney comes into effect. Between these two ways the Korean provisions regulating lasting power of attorney focus mainly on the first: as a prerequisite for valid contractual guardianship authentication of deed and lasting power of attorney comes into force only when Family Court examines the case and appoints a supervisory attorney. These requirements are blamed for not complying with the doctrine of guaranteeing autonomy coined by CRPD and for making the system unnecessarily expensive and difficult for access. In fact the statistic shows that the system of lasting power of attorney is much more used in the countries where the requirement for valid power of attorney and judicial intervention/supervision are scarce. However, in consideration of other factors, like that the German Courts are allowed to grant a judicial guardianship, even if a lasting power of attorney comes into effect, and therefore to control the attorney’s management, a comprehensive evaluation is needed for deciding how the risk from lasting power of attorney is dealt by the social and guardianship system. In my opinion an abandonment of ex-ante control could put the protection of adult in serious danger in considering that the ex-post supervision systems are not yet sufficient.

빈곤가정 아동,청소년의 자아탄력성 및 사회적 지지가 임파워먼트에 미치는 영향

김수정(Soo Jeong Kim) 한국아동복지학회 2008 한국아동복지학 Vol.- No.25

본 연구는 급식서비스를 받고 있는 빈곤가정 아동·청소년 207명을 대상으로 첫째, 빈곤가정 아동·청소년의 임파워먼트, 자아탄력성, 사회적 지지의 수준과 둘째, 임파워먼트, 자아탄력성, 사회적 지지의 관계 셋째 빈곤가정 아동·청소년의 임파워먼트에 영향을 주는 요인은 무엇인지를 파악하고자 하였다. 연구결과, 빈곤가정 아동·청소년들은 전반적으로 양호한 정도의 임파워먼트(3.56점)와 자아탄력성(3.41점)을 유지하고 있었으며, 대부분의 영역에서 초등학생과 중·고등학생 집단 간에는 유의미한 차이가 없었으나, 초등학생에 비해 중·고등학생들이 친구의 지지를 더 높게 지각하는 것으로 밝혀졌다. 임파워먼트 정도와 자아탄력성, 사회적 지지의 관계를 보면 임파워먼트와 자아탄력성이 가장 높은 정도의 정적 상관을 보여 주었으며, 사회적 지지 중에서 이웃의 지지는 임파워먼트나 자아탄력성과 유의미한 상관이 없는 것으로 나타났다. 마지막으로 전체 빈곤가정 아동·청소년의 임파워먼트에 영향을 주는 요인으로는 자아탄력성, 가족지지, 친구지지 그리고 가족구조였으며, 초등학생의 경우에는, full-model인 3단계에서 자아탄력성과 성별만이 영향 요인으로 드러났고, 중·고등학생의 경우에는 자아탄력성과 가족과 친구의 지지가 유의미한 영향을 미치는 요인으로 나타났다. The purpose of this study is to find empowerment and ego-resilience level of children & adolescent in poverty, and what influence on empowerment. Data came from the survey of 207 children & adolescent who are using lunch program in private social welfare agency. The results are as follows. First, the level of empowerment and ego-resilience of children & adolescent in poverty appear to be higher than mean score and the level of empowerment and ego-resilience of middle·high school students is higher than that of elementary school students. Second, in relationship between empowerment and ego-resilience, the poor children show a strong positive correlation. Third, the results of hierarchical regression analysis tell us that ego-resilience and social support are significant variables which influence on empowerment of the poor children. In case of elementary school students, ego-resilience is significant variable but social support is not. In case of middle·high school students, ego-resilience and support of Family and friends are significant variables. This study provide valuable knowledge about empowerment and ego-resilience of children & adolescent in poverty. And this study discuss the direction of future research and implication for strengthening empowerment and ego-resilience of children & adolescent in poverty.

한국과 중국의 어린이병원 대기공간 디자인특성 비교

김수정(Kim, Soo-Jeong),장신웨(Zhang, Xin-Yue),박수빈(Park, Soo-Been) 대한건축학회 2021 대한건축학회 학술발표대회 논문집 Vol.41 No.1

스트레스와 인지장애

김수정(Soo-Jeong KIm),변광호(Kwang-Ho Pyun),심인섭(Insop Shim) 대한스트레스학회 2005 스트레스硏究 Vol.13 No.4

천안 동남구청 도시재생을 위한 천안역 재설계 및 공간구성

김수정(Soo-Jeong Kim),김운용(Woon-Yong Kim),안희태(Hee-Tae An),최인락(In-Rak Choi) 호서대학교 공업기술연구소 2020 공업기술연구 논문집 Vol.39 No.2

천안역은 전국 유일의 임시역사로 운영되고 있으며, 과거 도심의 핵심지 역할을 했지만 현재는 역사 및 주변시설의 낙후화로 제 기능을 다하지 못하고 있다. 이 연구에서는 천안 동남구청의 도시재생 사업의 일환으로 천안역을 대상으로 쇠퇴한 원도심을 되살리기 위한 천안역 재설계를 진행하였다. 천안역 일대 교통의 원활한 순환을 위한 교통 계획인 지하차도와 역사 이용률 및 이미지 개선에 도움을 줄 수 있는 공방, 컨퍼런스 룸 등의 내부 공간 구성, 그리고 누각을 모티브로 한 외관 디자인 등을 계획하였다. 이 연구를 통해 천안역에 대한 이용객들의 관심을 극대화하고 천안역 일대의 상권 활성화 등을 통해 경제적 효과 또한 불러일으킴으로써 도시 이미지에 긍정적인 영향을 줄 수 있을 것으로 예상된다. Cheonan Station is operated as a temporary station in Korea, and it used to serve as a core city center in the past, but is currently not functioning due to the deterioration of the station and surrounding facilities. This study conducted a redesign of Cheonan Station to revive the declining original city center in Cheonan Station as part of the urban regeneration project of the Cheonan Dongnam-gu Office. The construction of an underpass, which is a transportation plan for the smooth circulation of traffic around Cheonan Station, and the construction of interior spaces such as workshops and conference rooms that can help improve the utilization rate and image of the station, and the exterior design with a pavilion motif were planned. Through this study, it is expected that it will have a positive effect on the image of the city by maximizing the interest of users in Cheonan Station and revitalizing the commercial district around Cheonan Station.

어린이전문병원 대기공간 실내디자인 개선방안 연구 - 부산시 어린이전문병원 현장조사와 면접조사를 중심으로 -

김수정(Kim, Soo-Jeong),박수빈(Park, Soobeen) 한국실내디자인학회 2020 한국실내디자인학회논문집 Vol.29 No.3

Children express stress through excessive behavior and negative emotional expression, not conversation, which delivers stress to people nearby. The purpose of this study is to find the environmental factors causing children"s stress and affecting positive emotion, which can be reflected in the waiting space design. The waiting space of nine hospital in Busan were prudently examined based on the interior design elements of floor, wall, ceiling, lighting, furniture, and color. through website, two among them were analyzed by the region including the informational and preparing area, the waiting area, and the playing area. Two faculties from each hospital took part in depth interview, Results and conclusions are as follows. (1) The floors of each hospital’s waiting space was designed neutral colored polishing tiles, which were plain and slippery. Additional non-slip installation and decorating stickers could be recommended for children to play. (2) Bright colored character graphic were applied to the walls considering visual stimulation. Various textured materials are recommend to the wall which enhance children’s activities through tactile stimulation as well as visual one. (3) The monotonous design of the ceiling was problematic. for the various activities of the children, the hall-centered design should be organically connected to the corridor to integrate the space. (4) The lighting was designed with focus on the hall. The hall design should be applied to the passage in consideration of the movement of children. (5) Fixed chairs restrict the movement of children. The sofa should be installed in a form without a backrest, taking into account the various body movements of the children. (6) Overly intense colors, patterns and dark colors can cause problems with space use. To alleviate visual stress, a combination of bright and pastel colors should be combined appropriately.