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      • KCI등재

        실크펩티드를 첨가한 빵이 Rat의 지질대사에 미치는 영향

        김영호,조남지,Kim, Young-Ho,Cho, Nam-Ji 동아시아식생활학회 2007 동아시아식생활학회지 Vol.17 No.2

        The aim of this study was to investigate the effect of bread supplemented with silkpeptide and cholesterol of on the lipid metabolism in rats. When a rats were fed bread supplemented with silkpeptide and cholesterol, their net weight tended to decrease compared with the control. Although the food intake was increased, this was not significant., but the feed efficiency ratio was substantially decreased. The total and LDL-cholesterols were decreased, but the DHL-cholesterol was increased. The HDL-cholesterol to total cholesterol ratio and level of triglyceride were substantially increased. The atherogenic index was decreased when rats are fed bread supplemented with silkpeptide and; thus, would show an improvement in the effect of high-cholesterol symptoms.

      • KCI등재

        천련자로부터 분리한 Limonoid 성분의 세포독성

        김영호,황방연,김세은,김환묵,오구택,노재섭,이경순,이정준,Km, Young-Ho,Hwang, Bang-Yeon,Kim, Se-Eun,Kim, Hwan-Mook,Oh, Goo-Taeg,Ro, Jai-Seup,Lee, Kyong-Soon,Lee, Jung-Joon 대한약학회 1994 약학회지 Vol.38 No.1

        The MeOH extract of the fruits of Melia toosendan was selected for futher study by its cytotoxicity and effect on the human breast cancer cell line, MCF-7. The active principle obtained by activity guided fractionation followed by purification gave rise to a needle crystal. The structure was deduced by employing NMR and was determined to be identical with 28-deacetyl sendanin by comparison with published data. This compound induced morphological change of MCF-7 to be rounded with tubule at concentrations between $50\;{\mu}g/ml$ and $0.025\;{\mu}g/ml$. This compound, however, showed strong cytotoxic effect on Hepalclc7 and HepG2, and their $GI_{50}$ on the hepatoma cell lines were $0.238\;{\mu}g/ml$ and $0.805\;{\mu}g/ml$, respectively. Its effect on lymphocyte of mouse was stronger than hepatoma cell lines, and their $ED_{50}$ of polyclonal antibody response was $0.011\;{\mu}g/ml$, and $ED_{50}$ of cell viability was $0.039\;{\mu}g/ml$.

      • KCI등재

        기후변화 시나리오에 따른 지역별 확률강우량

        김영호,여창건,서근순,송재우,Kim. Young-Ho,Yeo. Chang-Geon,Seo. Geun-Soon,Song. Jai-Woo 한국방재학회 2011 한국방재학회논문집 Vol.11 No.3

        본 연구는 A1B 기후변화 시나리오를 고려하여 지역별 확률강우량을 산정하고 관측소별 기존 관측자료의 특성을 고려한 적정 방법을 제안하였다. 이를 위하여 우리나라 주요 지점 강우관측소를 연구 대상지점으로 선정하여 선정된 주요 지점 관측소에 대해 24시간 연최대강우량 평균값과 매개변수의 관계를 분석하여 2100년의 빈도별 확률강우량을 산정하였다. 2100년 빈도별 확률강우량은 기상청 실측강우량 자료를 활용하여 산정하는 방법, 확률분포의 매개변수는 실측 강우자료를 활용하고, 2100년까지의 강우자료는 A1B 시나리오를 활용하는 방법, A1B 시나리오를 활용하여 확률강우량을 산정하는 3가지 방법을 적용하였다. A1B 시나리오에 의한 강우 예측값은 실측값 보다 과소 추정되어 이를 활용하는 경우에는 보정이 필요하며, 분위 사상법을 적용하여 보정한 결과 모든 관측소에서 약 2.3~3.0배의 강우량이 평균적으로 상향조정 되었다. 실측강우 자료만으로 산정한 확률 강우량의 경우, 강우량이 지속적으로 증가하여 과대 산정되어 증가하는 경향이 강하며, A1B 시나리오 자료를 활용하여 산정한 확률강우량의 경우 대체적으로 기존 관측자료의 증감율과 유사하게 산정되기는 하지만 지역적 특성을 정확히 반영하지 못하는 경우가 다소 발생하였다. 각 지점별로 24시간 연 최대 강우량 평균 증가율과 방법별로 산정된 확률강우량의 증가율을 비교하여 기후변화를 고려한 관측지점별 확률강우량 산정 방법을 선정하였다. This research proposes the suitable method for estimating the future probable rainfall based in 2100 on the observed rainfall data from main climate observation stations in Korea and the rainfall data from the A1B climate change scenario in the Korea Meteorological Administration. For all those, the frequency probable rainfall in 2100 was estimated by the relationship between average values of 24-hours annual maximum rainfalls and related parameters. Three methods to estimate it were introduced; First one is the regressive analysis method by parameters of probable distribution estimated by observed rainfall data. In the second method, parameters of probable distribution were estimated with the observed rainfall data. Also the rainfall data till 2100 were estimated by the A1B scenario of the Korea Meteorological Administration. Last method was that parameters of probable distribution and probable rainfall were estimated by the A1B scenario of the Korea Meteorological Administration. The estimated probable rainfall by the A1B scenario was smaller than the observed rainfall data, so it is required that the estimated probable rainfall was calibrated by the quantile mapping method. After that calibration, estimated probable rainfall data was averagely became approximate 2.3 to 3.0 times. When future probable rainfall was the estimated by only observed rainfall, estimated probable rainfall was overestimated. When future probable rainfall was estimated by the A1B scenario, although it was estimated by similar pattern with observed rainfall data, it frequently does not consider the regional characteristics. Comparing with average increased rate of 24-hours annual maximum rainfall and increased rate of probable rainfall estimated by three methods, optimal method of estimated future probable rainfall would be selected for considering climate change.

      • KCI등재

        수용성카이토산에 의한 마우스태반을 통한 태아로의 방사성스트론튬 급성 전이 억제

        김영호,범희승,김지열,Kim, Young-Ho,Bom, Hee-Seung,Kim, Ji-Yeul 대한방사선방어학회 1997 방사선방어학회지 Vol.22 No.4

        카이토산은 천연무독성 착화제의 일종으로 유전적 독성이 거의 없으며, 방사성스트론튬의 마우스 체내 축적을 감소시킨다고 알려져 왔다. 본 연구에서는 임신 17일째 마우스에서 방사성스트론튬 오염전 후에 수용성카이토산을 공급함으로써 오염 후 태반을 통한 태아로의 방사성스트론튬 급성 전이를 얼마나 효과적으로 억제할 수 있는 가를 알아보고자 하였다. 수용성카이토산 분말을 50일간 일반식이와 혼합하여 10% (Group 1), 1%(Group 2)를 공급하고 임신 17일째에 방사성스트론튬을 오염시킨 군의 경우 일반식이를 공급한 대조군과 방사성스트론튬 오염 후 카이토산 10%, 1%분말을 공급한 군(Group 3, Group 4)에 비해 태반을 통한 태아로의 방사성스트론튬 전이를 효과적으로 억제함을 관찰하였다(p<0.01, 표 1).본 실험을 통해서 임신 17일째에 방사성스트론튬에 오염된 임신마우스의 경우 천연무독성 착화제인 카이토산을 장기간 전처치하였을 경우 태반을 통한 태아로의 방사성스트론튬 전이를 억제할 수 있음을 알 수 있었다. It has been reported that chitosan has little genetic toxicity as one of natural and nontoxic chelator and reduces the internal retention of radiostrontium in the mouse. This study is to examine that when water soluble chitosan is provided to the mouse on 17 days of pregnancy before and after radiostrontium contamination, how effectively it can inhibit an acute transfer of radiostrontium to fetus through placenta contaminated. Water soluble chitosan powder is mixed with general food for 60 days and 10%(Group 1) and 1%(Group 2) are provided respectively, and it is observed that the group with radiostrontium contamination on 17 days of pregnancy can inhibit more effectively the transfer of radiostrontium to fetus through placenta than control group with general food and the groups (Group 3, Group 4) with 10% and 1% of chitosan powder respectively after radiostrontium contamination (p<0.01, Table 1). It is found that when the pregnant mouse contaminated by radiostrontium on 17 days of pregnancy is prefed by chitosan, the transfer of radiostrontium to fetus through placenta can be inhibited.

      • KCI등재

        동해안 ‘성주무가’에 나타난 성주의 신적(神的) 면모

        김영호(Kim, Young-ho) 한국어문학회 2016 語文學 Vol.0 No.131

        This paper focused on the “Sungju-Muga” of the East Coast was investigated the myth elements such acts and shape with a deity called “Sungju”. “Sungju-Muga” of the East Coast zone, the tradition is confirmed, also showing “Sungju-Muga” significant relevance in many different areas. In addition, there is a fact that the narrative something similar in shamanic chanting and Gosa(告祀) sori are present. In view of these large-scale tradition and magnificent homology, more universal content and format of “Sungju-Muga” will be found in the lore of the East Coast zone. And most of the evidence that appears in deified “Sungju-Muga” is focused on building a house “Sungju” has planted the trees that “Sungju-mok(木)”, cut it. Another important addition, this shape “Sungju” according to while having a shape as is blacksmith has appeared repeatedly in the subject to smelt the metal, creates a tool. “Sungju” is a messenger which mediates heaven and earth, has the shape of a carpenter and architect to build a house that linked by causal and logical. At the same time can be understood as forming the series of the symbol means that the artificial culture, as opposed to natural. Acts of “Sungju” takes advantage of the natural, mythical incident that as first in the cultural life of residents, shows the origin meaning. And, deity of such a personality, from the point of view of mythology, not only the same quality of the sacred, is a half-body presence to share the human attributes and directivity, is portrayed as a culture hero. So “Sungju” from “Sungju- Muga” of the East Coast area is not only to implement the meaning of primordial creation, in particular, have a discrimination of that the beginning of the act of human culture, this is sustained even in the context of the tradition.

      • KCI등재

        태연(太淵)(L<sub>9</sub>)자침(刺鍼)이 태연(太淵)(L<sub>9</sub>)과 중부(中府)(L<sub>1</sub>)영역(領域)의 온도변화(溫度變化)에 미치는 영향(影響)

        김영호,송범용,육태한,Kim, Young-ho,Song, Beom-Yong,Yook, Tae-han 대한침구의학회 2001 대한침구의학회지 Vol.18 No.5

        Backgrounds and purpose : The acupuncture of oriental medicine is very important in treatments. Until now it was been researched according to the meridian and qi xue(氣血) phenomenon of oriental medicine's theory. Acupuncture will show more objective index to observe the meridian. And then, I studied the effects on the thermal change of the Taeyon($L_9$) and Chungbu($L_1$) following acupuncture stimulation. Objective and Methods : This study was performed from December 1999 to February 2000 on 60 healthy students. The objective was divided into two groups, those are the control group A(N=30) that no acupuncture stimulation, the group B(N=30) of acupuncture stimulation on Taeyon($L_9$). First, in the control group A, I took a picture Taeyon($L_9$) Chungbu($L_1$) Taenung($P_7$) Chondol($CV_{22}$) area for 30 men without any stimulation with the Digital Infrared Thermograph Imaging(D.I.T.l.) and did same area, 10min after. Second, in the acupuncture stimulation group B, we took a picture Taeyon($L_9$) Chungbu($L_1$) Taenung($P_7$) Chondol($CV_{22}$) area for 30 men without any stimulation with the Digital Infrared Th - ermograph Imaging(D.I.T.I.), and then stimulate acupuncture on Taeyon($L_9$) and took a picture same area, 10min after. Results : 1. In healthy men, average skin temperture on Taeyon($L_9$) area was lower than Chungbu($L_1$) area about $3.0^{\circ}C$, in the Lt. Taeyon($L_9$) and Chungbu($L_1$) area was lower than Rt. Taeyon($L_9$) and Chungbu($L_1$) area. 2. In the acupuncture stimulation group B, the skin temperature of both side Taeyon($L_9$) area showed the increase or decrease significantly. But both Taenung($P_7$) area did not showed significantly. 3. In the acupuncture stimulation group B, the skin temperature of both side Chungbu($L_1$) area showed the increase or decrease significantly. But both Chondol($CV_{22}$) area did not showed significantly. 4. The thermal changes of the area which is a meridian point in the Lung Meridian of the acupuncture stimulation group on Taeyon($L_9$) different from other Meridian with significantly change. Conclusion : The acupuncture stimulation on Taeyon($L_9$) affected the thermal change of the area which is a meridian point, in the Lung Meridian. And then I could relate these results with the existence of the meridian and meridian point. Thus, continuous thermographic study will be needed for the existence of the meridian and meridian point.

      • KCI등재

        로그기반 상황인식에 의한 소규모 창고관리시스템

        김영호,최병용,전병환,Kim, Young-Ho,Choi, Byoung-Yong,Jun, Byung-Hwan 한국정보처리학회 2006 정보처리학회논문지B Vol.13 No.5

        유비쿼터스 컴퓨팅의 일환으로 무선인식(RFID)을 이용한 많은 응용시스템이 개발되고 있으며, 특히 물류산업에 RFID 칩이 널리 보급될 것으로 예측된다 중소업체의 경우 소규모 창고관리에도 비용과 인력 측면에서 어려움을 격고 있는 상황에서 효율적이고 정확한 지능형 창고관리 시스템의 필요성이 절실하다. 본 논문에서는 로그기반 상황인식 기술을 이용하여 소규모 창고관리시스템을 구현한다. RFID 리더기를 제어하는 클라이언트를 구성하고 서버에 DBMS 시스템을 구축하여 웹상에서 운영되는 창고관리시스템을 구현한다. 특히, 시스템 접근 이력에 대한 로그데이터를 토대로 사용자의 입출고 의도를 파악하며, 관리자에게 사용자의 비정규적인 창고사용 패턴을 보고하고 예측 가능한 재고관리 서비스를 제공한다. 결과적으로, 제안한 시스템은 소규모 창고관리의 효율성과 정확도를 향상시키는데 기여할 수 있다. Various application systems are developed using RFID as a part of ubiquitous computing, and it is expected that RFID chip will become wide-spread for the distribution industry especially. Efficient and efact intelligent-type of warehouse management system is essential for small-to-medium-sized enterprises in the situation having a trouble in the viewpoint of expense and manpower. In this paper, we implement small-scale warehouse management system using log-based context awareness technology. This system is implemented to be controlled on web, configuring clients to control RFID readers and building up DBMS system in a server. Especially, it grasps user's intention of storing or delivering based on toE data for the history of user's access to the system and it reports user's irregular pattern of warehouse use and serves predictive information of the control of goods in stock. As a result, the proposed system can contribute to enhance efficiency and correctness of small-scale warehouse management.

      • SCOPUSKCI등재

        감국의 품질 평가

        김영호,민병선,정현주,하티탄훵,이준성,지형준,배기환,Kim, Young-Ho,Min, Byung-Sun,Jung, Hyun-Ju,Lee, Jun-Sung,Chi, Hyung-Joon,Bae, Ki-Hwan 한국생약학회 1999 생약학회지 Vol.30 No.1

        The flower of Chrysanthemum morifolium L. has been used as 'Kamguk' in the Korean markets instead of it from C. indicum L. In order to evaluate the quality of Chrysanthemi Flos, the method for isolation and quantitative determination of luteolin as standard compound has been developed. It is analyzed with HPLC using the solvent system of MeOH-water-acetic acid (30:70:5). The amounts of luteolin from Chrysanthemi Flos in Korean markets are in the range of $0.03{\sim}0.04%.$ The amounts of luteolin from the flowers of C. indicum and C. boreale are approximately 0.14% and 0.04%, respectively.

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