韓方保建 指導業務 付與의 當位性

朴贊國 대한한의학원전학회 1988 대한한의학원전학회지 Vol.1 No.2

후설의 현상학과 후기하이데거의 현상학에 대한 비교연구

박찬국 한국철학회 1997 철학 Vol.52 No.-

스트랩다운 관성항법시스템의 최적 자세계산 알고리즘 개발

박찬국,김광진 광운대학교 신기술연구소 1996 신기술연구소논문집 Vol.25 No.-

본 논문에서는 스트랩다운 관성항법시스템의 원추운동 오차를 최소로 하는 최적의 자세계산 알고리즘을 제시한다. 제시된 알고리즘은 갱신 주기마다 6개의 자이로 샘플을 이용하고 간단한 행렬형태로 표시되었다. 기존의 5-샘플 알고리즘과 제시된 알고리즘의 성능을 비교하기 위하여 원추운동주파수와 샘플링 주파수 그리고 원추 반각을 변화시키면서 알고리즘 오차를 시뮬레이션 하였다. 그 결과 고주파의 원추운동에서는 6-샘플 알고리즘이 5-샘플 알고리즘 보다 우수한 성능을 나타냄을 제시하였다. In this paper, an optimal attitude algorithm for a strapdown inertial navigation system is proposed by minimizing the coning error. The proposed algorithm takes six samples of gyro data per update and has been expressed as a matrix form. To compare the performance of the proposed algorithm with an already existing five-sample algorithm, a simulation has been performed by varying coning motion frequency, sampling frequency and coning half angle. Results show that the six-sample algorithm outperforms the five-sample algorithm in the case of high-frequency coning motion.

韓醫學과 西洋醫學의 疾病觀에 대한 比較硏究

白上龍,朴贊國 慶熙大學校韓醫科大學韓醫學硏究所 1998 慶熙韓醫大論文集 Vol.21 No.1

In the first step that medicine had became a study, a disease ment the pain that people suffered, in both the Oriental medicine(韓醫學) and the Western medicine. But the Oriental medicine and the Western medicine have typical opinion each other in the progress of sysytematizing the medicine. And, the reason that their cognition of the disease has been changed stems from the differences of view of the world, and the element of culture and society, which belongs to concerned scholars. The ideology and theory of ancient chineses who are considered as a constructors of the Oriental medicine's basis are formed from the attitude to adjust and accept the changes in the nature according to senses they feel. To adjust the nature, understanding of nature's rule was their priority. 'Yin-Yang and Five-phase theory(陰湯五行理論)' as systematized as a principle by recognizing nature's rule through those effects, and qi(氣) is appeared. which help everything exist as a perfect indivisual. And, they regarded continuously various changes of nature is due to the change of qi under the 'Yin-Yang and Five-phase theory'. For creature like a man is regarded as a change of qi, according to the rule of 'Yin-Yang and Five-phase theory', also the soul controling lives was regarded as temporary result revealed in the process of the change in qi's Yin-Yang and Five-phase(陰陽五行). that view of nature is established as a universal ethics to nature and human through a book, 'the Hwang-Ge-Nae-Kyung(黃帝內經)' and forms the basis theory of the Oriental medicine. Early the Western medicine differs from present one. The 'Body fluid theory(體液學說)' of early the Western medicine, represented by Hippocrates and Galen, tried to get an answer to the physiology and pathology through the growth of body fluid. In other words, it regards man's secretion or body wound or anatomy as a cause of disease and living as well. This body fluid correspond to the qi, considered as the origin of a life in the Oriental medicine, in that it is movable and unclear in each domain. The similarity between qi and body fluid, movable and changable, is the main reason that the surgery has not developed within these two theories. But, though body fluid is something visible and is changable in condition of liquid, it doesn't have such features as qi that can variously change into solid, liquid, energy, soul, and so on. So to speak, qi contains all imaginable features of objects in its conception. In contrast, body fluid is only a fluid that can control the physiological function. The Oriental medicine regards the disease as disorder of qi, also body fluid pathology says that the disease is a disorder of body fluid. Thus, both has consistent opinion about disease in the point of disorder. O.M.D(韓醫學者) thought the all disorder of mind and body, disorder between mind and body, even a change in nature were caused by the change of qi. But, because body fluid pathology couldn't explain that such organization as human, animal, and plant has a relationship with another objects. It could define a disease as a matter phenomenon like disorder of body fluid, but couldn't reach to find the consistency among the various objects in nature. Since the Oriental medicine thought of disease as breakage of Yin-Yang balance(陰陽調和) in other words abnormal function. Four great doctor in Kum and Won dinasty(金元四大家) tried to understand feature of disease, which caused a disease, and pathogenesis by explaining sa-qi(邪氣 bad effect making body function disorder) and peculiarity of patient's body rather than disease itself. Ha-Ghan(河間), who understood pathological mechanism through etiology itself, explained the process and feature of disease. In contrast Won-So(元素) and Dong-Won(東垣), who tried to understand the pecularity of disease through physiologycal mechanism tried to understand pathologycal mechanism between living energes, so to speake Wui-qi(胃氣), and 'yum-hwa(陰火)' which generates in abnormal function. The the Western medicine faced the new wave from the late of 17C, and then in paris where often the new era of clinical medicine. Solid pathology generally came to the front of fluid pathology with Bichat insistance that disease is not invalance of body fluid but chance of original shape and quality in late 18C. In solid pathology disease is not regarded as abnormally quantative and functional condition but as change of original shape and quality. This view is based on Descartes and newton's 'machanic view of the world'(機械的世界觀), which converted the way of western thinking since 17C. and the feature of this view regards disease as an object itself, and separate disease from a patient. The disease degraded over different nature which has none relative with living creature.

MATLAB을 이용한 관성항법장치의 오차 시뮬레이터 개발

박찬국,진용 광운대학교 신기술연구소 1997 신기술연구소논문집 Vol.26 No.-

본 논문에서는 MATLAB의 Simulink를 사용하여 관성항법장치의 항법 오차 분석을 위한 시뮬레이터를 개발하고 항법 성능을 분석하였다. 제작된 시뮬레이터는 MATLAB에서 사용자와의 인터페이스가 용이하도록 그래픽 형태로 구성되었으며 초기정렬 오차 및 운항 중 항법오차 알고리즘을 포함한다. 시뮬레이터의 동작을 보이기 위하여 자이로와 가속도계의 사양과 초기 오차에 따른 초기 정렬시의 자세오차와 운항 중의 수평축에서의 슐러진동 오차 및 수직축의 고도계를 이용한 감쇠 알고리즘 오차 결과를 제시하였다. This paper presents the simulator for an error analysis of Inertial Navigation System (INS) using MATLAB with Simulink and analyzes the navigation performance. The simulator supports the Graphic User Interface(GUI) with MATLAB and includes the initial alignment error and in-flight navigation error algorithms. In order to show the operation of the simulator, the initial errors in alignment mode, and horizontal axes errors with Schuler oscillation and vertical axis error damped by an altimeter in navigation mode are analyzed according to the gyro and accelerometer specifications.

생쥐 소장의 interstitial cells of Cajal에서 ATP-민감성 K^(+)통로를 통한 향도잡이 전류의 조절

박찬국,김만우,김형석,최석,전제열 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.1

Objectives: This study was performed to investigate whether ATP-sensitive K^(+) channels exist in interstitial cells of Cajal (ICC) of mouse small intestine and the physiological role of ATP-sensitive K^(+) channels in gastrointestinal motility. Methods: ICC were isolated from mouse small intestine and cultured for 2 days. Electrical activities of ICC were recorded using the whole-cell patch-clamp technique at 30°C. Results: ICC displayed rhythmic slow waves and spontaneous inward currents (pacemaker currents). Pinacidil, an ATP-sensitive K^(+) channel opener, induced membrane hyperpolarization and decreased amplitude of slow waves in current clamping mode. Also, pinacidil inhibited amplitude and frequency of pacemaker currents and activated outward currents at a holding potential of -70 mV. Pinacidil effects on slow waves and pacemaker currents were blocked by glibenclamide, a specific blocker of ATP-sensitive K^(+) channel. Forskolin, an activator of adenylate cyclase, induced membrane hyperpolarization and inhibited pacemaker currents like as pinacidil and blocked by glibenclamide. Conclusions: These results suggest that ATP-sensitive K^(+) channels exist in ICC and may be play an important role in regulating gastrointestinal motility through the modulation of pacemaker activities of ICC.

한약제 복용으로 인한 연중독 1례

박찬국,김용균,박상호,정춘해,조건국 조선의대 1985 The Medical Journal of Chosun University Vol.10 No.1

생쥐 대장 평활근에서 막전압-의존성 이온 전류에 대한 tamoxifen 효과

박찬국,허광식,장성종,김만우,윤영,박도영,양경철,신무경,차경훈,염철호,윤평진,전제열 조선대학교 2003 The Medical Journal of Chosun University Vol.28 No.1

Background and Objectives : Tamoxifen is a widely used anticancer drug for breast cancer causing frequent gastrointestinal side effects. The change of gastrointestinal motility is associated with the alteration of activities of membrane ion channels. The ion channel is found to play an important role in regulating membrane potential and cell excitability. This study was performed to investigate the effects of tamoxifen on the membrane ionic currents in colonic myocytes. Materials and Methods : Single colonic myocytes were isolated by using a collganase from murine proximal colon. The membrane currents were recorded by using a whole-cell patch clamp method at room temperature. Results : Two types of voltage-dependent K+ currents (A-type and delayed rectifier K+ currents) were recorded. Tamoxifen inhibited both types of voltage-dependent K+ currents (10 μM). However, tamoxifen did not change the half-inactivation potential and the recovery time of voltage-dependent K+ currents. Chelerythrine, a protein kinase C inhibitor, and phorbol-12,13-dibutyrate, a protein kinase C activator, did not affect the voltage-dependent K+ currents Guanosine 5-O-2-thiodiphosphate (GDPβS, a G-protein inhibitor), also did not affect on tamoxifen-induced inhibition of voltage-dependent K+ currents. In audition, tamoxifen completely inhibited the voltage-dependent Ca²+ currents in whole-test ranges. Conclusion : These results suggest that tamoxifen inhibits the voltage-dependent membrane ionic currents in colonic smooth muscle cells, and that this action may be relevant to the gastrointestinal side effects

위암에서 맥관형성 정도와 vascular endothelial growth factor(VEGF) 발현에 관한 연구

박찬국,김창홍,최호열 의과학연구소 1998 全北醫大論文集 Vol.22 No.2

차이와 갈등에 대한 철학적 성찰 : 서양철학에서 본 차이와 갈등 ; 서양 전통형이상학으로부터 본 차이 / 논평

박찬국,박인철 한국철학회 2006 춘계학술대회 Vol.2006 No.-