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Zhang, Yi,Zhang, Wei-Ling,Huang, Dong-Sheng,Hong, Liang,Wang, Yi-Zhuo,Zhu, Xia,Hu, Hui-Min,Zhang, Pin-Wei,Yi, You,Han, Tao Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.8
Objective: This study aimed to investigate the effect of multimodality treatment of advanced paediatric hepatoblastoma (HB) and the factors affecting prognosis. Methods: A total of 35 children underwent multimodality treatments consisting of chemotherapy, surgery, interventional therapy, and autologous peripheral blood stem cell transplantation. The patients were followed up every month. Results: Serum AFP levels in 33 out of 35 patients in this study were significantly increased (P = 0.0002). According to the statistical scatter plot, the values of serum AFP on the 25th, 50th, and 75th percentages were 1,210, 1,210 and 28,318 ng/dl, respectively. Of the 35 cases, 21 were stage IV. 18 cases were treated with systemic chemotherapy before surgery, and 3 cases with locally interventional chemotherapy before surgery. Statistical analysis showed that the preferred interventional treatment affected prognosis, and that there was a statistically significant difference (P = 0.024). Some 33 patients completed the follow-up, of which 17 were in complete remission (CR), 5 were in partial remission (PR), 1 became disease progressive (DP), and 10 died. The remission and overall survival rates were 66.7% (22/33) and 69.7% (23/33), respectively. Patients with the mixed HB phenotypes had worse prognoses than the epithelial phenotype (P < 0.001), and patients in stage IV had a lower survival rate than those in stage III (P < 0.001). Conclusion: Multimodality treatment can effectively improve remission rate and prolong the survival of children with advanced HB. In addition, alpha-fetoprotein (AFP), a tumor marker of liver malignant tumors, HB pathological classification, and staging are highly useful in predicting prognosis.
Study on Aging Characteristics and Chemical Composition of Hydrogenated Transformer Oil
Yi-Hua Qian,Yi-Bin Huang,Qiang Fu,Zhen-Sheng Zhong 대한전기학회 2013 Journal of Electrical Engineering & Technology Vol.8 No.3
Under the condition of Baader aging, the chemical composition variation and the influence of transformer oil aging on electrical properties such as dielectric loss factor and physicchemical properties such as interfacial tension were studied in the aging precess. Moreover, the correlation between hydrogenated transformer oil electrical and physic-chemical properties and its chemical composition variation were also investigated. The results show that these parameters of physic-chemical and electrical properties of hydrogenated transformer oil relate to each other and have closed correlation with chemical composition.
Yi Zou,Linying Chen,Xingfu Wang,Yupeng Chen,Liwen Hu,Saifan Zeng,Pengcheng Wang,Guoping Li,Ming Huang,Liting Wang,Shi He,Sanyan Li,Lihui Jian,Sheng Zhang 대한위암학회 2019 Journal of gastric cancer Vol.19 No.1
Purpose: The significance of neuroendocrine differentiation (NED) in gastric carcinoma (GC) is controversial, leading to ambiguous concepts in traditional classifications. This study aimed to determine the prognostic threshold of meaningful NED in GC and clarify its unclear features in existing classifications. Materials and Methods: Immunohistochemical staining for synaptophysin, chromogranin A, and neural cell adhesion molecule was performed for 945 GC specimens. Survival analysis was performed using the log-rank test and univariate/multivariate models with percentages of NED (PNED) and demographic and clinicopathological parameters. Results: In total, 275 (29.1%) cases were immunoreactive to at least 1 neuroendocrine (NE) marker. GC-NED was more common in the upper third of the stomach. PNED, and Borrmann's classification and tumor, lymph node, metastasis stages were independent prognostic factors. The cutoff PNED was 10%, beyond which patients had significantly worse outcomes, although the risk did not increase with higher PNED. Tumors with ≥10% NED tended to manifest as Borrmann type III lesion with mixed/diffuse morphology and poorer histological differentiation; the NE components in this population mainly grew in insulae/nests, which differed from the predominant growth pattern (glandular/acinar) in GC with <10% NED. Conclusions: GC with ≥10% NED should be classified as a distinct subtype because of its worse prognosis, and more attention should be paid to the necessity of additional therapeutics for NE components.
Novel Deadlock Control for Smartphone Manufacturing Systems Using Petri Nets
Yi-Nan Lin,Sheng-Kuan Wang,Gwo-Jen Chiou,Cheng-Ying Yang,Victor R. L. Shen,Tony Tong-Ying Juang,Ting-Jui Huang 제어·로봇·시스템학회 2022 International Journal of Control, Automation, and Vol.20 No.3
Currently, the marketing strategy in the manufacturing industry is becoming more and more competitive. Thus, the production efficiency becomes the main developing trend, which many people are now pursuing. However, the automatic production might cause resource conflicts and system deadlocks. In this study, Petri net models and analysis were used to effectively avoid deadlocks and to achieve the goal of lean production. The iPhone XS device developed by Apple is now a popular product. Consequently, this paper aims to describe its manufacturing system by using Petri net models. Meanwhile, the siphon property of Petri nets can be used to detect the deadlock in the manufacturing processes and to avoid it from occurring. Two simulation software tools, WoPeD and PIPE, were applied to conduct the experiments. The experimental results have indicated that our proposed approach is more feasible and acceptable than other existing ones.
Study on Aging Characteristics and Chemical Composition of Hydrogenated Transformer Oil
Qian, Yi-Hua,Huang, Yi-Bin,Fu, Qiang,Zhong, Zhen-Sheng The Korean Institute of Electrical Engineers 2013 Journal of Electrical Engineering & Technology Vol.8 No.3
Under the condition of Baader aging, the chemical composition variation and the influence of transformer oil aging on electrical properties such as dielectric loss factor and physic-chemical properties such as interfacial tension were studied in the aging precess. Moreover, the correlation between hydrogenated transformer oil electrical and physic-chemical properties and its chemical composition variation were also investigated. The results show that these parameters of physic-chemical and electrical properties of hydrogenated transformer oil relate to each other and have closed correlation with chemical composition.
Yaping Sheng,Qigu Huang,Haibing Huang,Mengshan Yu,Xinli Zhang,Lu Cheng,Zhi Liu,Wei Liu,Jianjun Yi,Wantai Yang 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.2
The copolymerization of MMA with ethylene was promoted by metallocene complex in the presence ofinitiator tetra(2,3-epoxy propoxy)silane (Is), reducing agent Zn and cocatalyst MAO, combining freeradical polymerization with coordination polymerization via sequential monomer addition strategy inone-pot to produce 4-arms hydroxy-functionalized PMMA-b-PE. The effects of polymerizationconditions such as temperature, time, ethylene pressure and Al/Ti molar ratio on the polymerizationperformance were investigated. 4-Arms hydroxy-functionalized PMMA-b-PE was obtained by solventextraction and determined by GPC, MALLS, DSC, FT-IR, WAXD and 1H(13C) NMR. The DSC result indicatedthat the 4-arms hydroxy-functionalized PMMA-b-PE had one Tg at 87.0 ℃ and one Tm at 117.0 ℃ whichattributed to Tg of PMMA segment and Tm of PE segment, respectively. The microstructure of 4-armshydroxy-functionalized PMMA-b-PE was further confirmed by WAXD, FT-IR, and 13C NMR analysis. These results demonstrated that the obtained 4-arms block copolymer consisted of PMMA segment andcrystalline PE segment.
( Ssu-yi Lu ),( Xiang-guan Deng ),( Sheng-shu Huang ),( Chun-yu Tsai ),( Chyung Ay ) 한국농업기계학회 2018 한국농업기계학회 학술발표논문집 Vol.23 No.1
With the pressure of society and the large population of insomnia, the sleep problem is becoming more and more serious as the population ages. This study hopes to replace medicines with music and enable patients to relax and enter sleep more quickly. According to clinical experiments, hemi-sync can relax the body and mind and improve the difficulty of sleep. In this experiment, 3.4Hz binaural beats with three different styles of our own sleeping piano music were tested on college students. Emotiv 14-channel wireless EEG device was used to measure and record, analyze the experimental data and present as the spectrogram. For each music beats style, 30 students were selected to perform listening experiments. Calculated the success rate of hemi-sync generated by EEG device, and compared the degree of influence of the three music pieces on the listeners and the differences of frequency band in EEG. The experiment results showed that the hemi-sync appear, with a success rate of more than 40%. Different styles of binaural beats piano music and hemi-sync provide a variety of styles of self-created beats piano music for the public to choose, to shorten the time required to get into sleep and solve the problem of insomnia. In addition, we must observe the feasibility of hemi-sync to the subjects. Using the machine learning algorithm, it was found that in the F7 of the brain area, the accuracy of using the RF algorithm can reach 70.1%, while using XGB it reaches 70.4%, which means that the detection of correlation of hemi-sync and F7 in EEG can improve the verification of the influence of binaural beats on EEG. It shows a clear picture in the future that the beats music can influence the brain, so that people with insomnia can be treated with the most suitable music.
Laser-induced heating for cell release and cellular DNA denaturation in a microfluidics
Min-Sheng Hung,Yi-Tsung Huang 한국바이오칩학회 2013 BioChip Journal Vol.7 No.4
In this study, a microfluidics is integrated with a laser to develop a microfluidic system for singlecell capture and cellular DNA denaturation. The results show that the cells encountered low hydrodynamic stress at low velocities and, thus, could be captured by a cell capture structure. Laser heating of the solution at low velocity produced bubbles that pushed the cells away from the capturing areas. The released cells were subsequently lysed, and cellular DNA was extended and immobilized on the surface of pillars before undergoing laser heating to induce partial denaturation.
Survival Analysis of Oral Squamous Cell Carcinoma in a Subgroup of Young Patients
Fan, Yi,Zheng, Lei,Mao, Ming-Hui,Huang, Ming-Wei,Liu, Shu-Ming,Zhang, Jie,Li, Sheng-Lin,Zheng, Lei,Zhang, Jian-Guo Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.20
Oral squamous cell carcinoma (OSCC) is predominantly a disease of middle-aged men with long-term exposure to tobacco and alcohol. An increasing trend has been reported at a younger age worldwide. Clinical records of 100 patients under the age of 45 years treated specifically for oral cavity SCC in our hospital during a 10-year period were retrospectively analyzed to calculate the survival rates. An obvious male predominance coincided with smoking trend among Chinese young individuals and female patients were more likely to have no traditional risk factors such as smoking or drinking. The 5-year overall survival rate and disease-free survival rate were 61.0% and 75.5%, respectively, consistent with other published series over the decade showing a relatively better survival among the young. No significant differences clearly correlated with outcome when comparing non-smokers non-drinkers to ever-smokers and ever drinkers (P>0.05). Overall survival rate and disease free survival rate was found to be significantly higher in patients with early-stage disease than with advanced stage disease (P=0.001, P=0.009 respectively). The strong influence of clinical stage on prognosis emphasizes the importance of early diagnosis and treatment of oral malignancies for this unique clinical subgroup.