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Huang Chia-Yu,Wu Mei-Yao,Huang Ming-Cheng,Yu Teng-Shun,Yen Hung-Rong 한국한의학연구원 2023 Integrative Medicine Research Vol.12 No.3
Background: The pressure ulcer is a complication from dementia. The aim of this study is to study the association between the developing of pressure ulcers and the use of acupuncture therapy in patients with dementia. Methods: We performed a retrospective 1:1 propensity score-matched cohort study to investigate the association between acupuncture therapy and the risk of pressure ulcers in patients with dementia. Results: A total of 8,994 patients were identified, 237 patients in the acupuncture cohort and 362 patients in the no-acupuncture cohort developed pressure ulcers. A reduced cumulative incidence of pressure ulcers was observed in the acupuncture cohort (P < .001). The association between acupuncture and reducing the incidence of pressure ulcers was not affected by sex, age, residence, income, or comorbidities. The variables of etiologies to cause dementia did not change the final result. In the subgroups analyses, the patients without medication for dementia controlling had significant lower rate of pressure ulcers development when they had accepted acupuncture therapy (log-rank test, P <.001). Conclusion: Our results revealed the association between acupuncture therapy and a reduced incidence of pressure ulcer development in patients with dementia. This finding offers important ideas for further research.
Ming Huang,Lijun Wang,Xiaojuan Zhang,Jin Zhou,Lihua Liu,Yuefang Pan,Bin Yu,ZHANGSEN YU 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2017 NANO Vol.12 No.5
Upconversion nanoparticles (UCNPs) are widely used in the field of biomedicine, such as biosensing, cell labeling and medical multimodal imaging because of their unique optical properties. In this paper, we demonstrated the synthesis of polyethylenimine-modified NaLuF4:Yb,Er (RE = Lu 0.78, Yb 0.18, Er 0.02) UCNPs in three different solvents, such as water, ethylene glycol and diethylene glycol. The as-prepared UCNPs were characterized and the experimental results showed that the UCNPs synthesized in ethylene glycol had excellent properties. The obtained UCNPs in ethylene glycol had the smallest particle size and uniform size distribution, and the pure cubic phase of crystallization and Dynamic light scattering and particle dispersion index (DLS/Pdi) were the smallest. What's more, the upconversion fluorescence intensity was 7 and 52 times greater than that of UCNPs synthesized in diethylene glycol and water, respectively. In addition, the factors of reaction solvent that had an impact on the particle size, morphology, crystalline phase, DLS and upconversion fluorescence intensity of the synthesized UCNPs were discussed. Moreover, in order to obtain the targeted nanoprobe, we used an EDC/NHS covalent coupling method to modify folic acid to the NaLuF4:Yb,Er/PEI UCNP surface. The NaLuF4:Yb, Er/PEI–FA upconversion fluorescent nanoprobes had low cytotoxicity and were suitable for the application in HeLa cells targeted fluorescent imaging.
A SUPERLINEAR $\mathcal{VU}$ SPACE-DECOMPOSITION ALGORITHM FOR SEMI-INFINITE CONSTRAINED PROGRAMMING
Huang, Ming,Pang, Li-Ping,Lu, Yuan,Xia, Zun-Quan The Korean Society for Computational and Applied M 2012 Journal of applied mathematics & informatics Vol.30 No.5
In this paper, semi-infinite constrained programming, a class of constrained nonsmooth optimization problems, are transformed into unconstrained nonsmooth convex programs under the help of exact penalty function. The unconstrained objective function which owns the primal-dual gradient structure has connection with $\mathcal{VU}$-space decomposition. Then a $\mathcal{VU}$-space decomposition method can be applied for solving this unconstrained programs. Finally, the superlinear convergence algorithm is proved under certain assumption.
Comparative study on dynamic properties of argillaceous siltstone and its grouting-reinforced body
Huang, Ming,Xu, Chao-Shui,Zhan, Jin-Wu,Wang, Jun-Bao Techno-Press 2017 Geomechanics & engineering Vol.13 No.2
A comparison study is made between the dynamic properties of an argillaceous siltstone and its grouting-reinforced body. The purpose is to investigate how grout injection can help repair broken soft rocks. A slightly weathered argillaceous siltstone is selected, and part of the siltstone is mechanically crushed and cemented with Portland cement to simulate the grouting-reinforced body. Core specimens with the size of $50mm{\times}38mm$ are prepared from the original rock and the grouting-reinforced body. Impact tests on these samples are then carried out using a Split Hopkinson Pressure Bar (SHPB) apparatus. Failure patterns are analyzed and geotechnical parameters of the specimens are estimated. Based on the experimental results, for the grouting-reinforced body, its shock resistance is poorer than that of the original rock, and most cracks happen in the cementation boundaries between the cement mortar and the original rock particles. It was observed that the grouting-reinforced body ends up with more fragmented residues, most of them have larger fractal dimensions, and its dynamic strength is generally lower. The mass ratio of broken rocks to cement has a significant effect on its dynamic properties and there is an optimal ratio that the maximum dynamic peak strength can be achieved. The dynamic strain-softening behavior of the grouting-reinforced body is more significant compared with that of the original rock. Both the time dependent damage model and the modified overstress damage model are equally applicable to the original rock, but the former performs much better compared with the latter for the grouting-reinforced body. In addition, it was also shown that water content and impact velocity both have significant effect on dynamic properties of the original rock and its grouting-reinforced body. Higher water content leads to more small broken rock pieces, larger fractal dimensions, lower dynamic peak strength and smaller elastic modulus. However, the water content plays a minor role in fractal dimensions when the impact velocity is beyond a certain value. Higher impact loading rate leads to higher degree of fragmentation and larger fractal dimensions both in argillaceous siltstone and its grouting-reinforced body. These results provide a sound basis for the quantitative evaluation on how cement grouting can contribute to the repair of broken soft rocks.
Raman Spectral Band Oscillations in Large Graphene Bubbles
Huang, Yuan,Wang, Xiao,Zhang, Xu,Chen, Xianjue,Li, Baowen,Wang, Bin,Huang, Ming,Zhu, Chongyang,Zhang, Xuewei,Bacsa, Wolfgang S.,Ding, Feng,Ruoff, Rodney S. American Physical Society 2018 Physical Review Letters Vol.120 No.18
<P>Raman spectra of large graphene bubbles showed size-dependent oscillations in spectral intensity and frequency, which originate from optical standing waves formed in the vicinity of the graphene surface. At a high laser power, local heating can lead to oscillations in the Raman frequency and also create a temperature gradient in the bubble. Based on Raman data, the temperature distribution within the graphene bubble was calculated, and it is shown that the heating effect of the laser is reduced when moving from the center of a bubble to its edge. By studying graphene bubbles, both the thermal conductivity and chemical reactivity of graphene were assessed. When exposed to hydrogen plasma, areas with bubbles are found to be more reactive than flat graphene.</P>