Poster Session : PS 0831 ; Upper GI Tract : Clinical Factors to Predict Angiographically Detectable Non-Variceal Upper Gastrointestinal Bleeding in Patients Refractory to Endoscopic Treatment

( Tae Hwan Ha ),( Tae Hoon Oh ),( Sung In Yu ),( Min Kim ),( Jong Wook Kim ),( Won Ki Bae ),( Jae Hyung Kim ),( Seung Suk Baek ),( Mi Jin Ryu ),( Ye Na Choi ),( Ji Young Park ),( Eileen L Yoon ),( Tae 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Background: Non-variceal upper GI bleeding (NVUGIB) is a common medical problem that has signifi cant association with morbidity and mortality. Angiographic detection and subsequent transarterial embolization (TAE) is a primary treatment option when medical and endoscopic treatments fail. We investigated clinical factors that could affect the success of the angiographic detection and prognosis after TAE in patients with NVUGIB refractory to endoscopic therapy. Methods: A retrospective analysis of the clinical data was done in patients with failed endoscopic treatment who underwent angiography for the treatment of acute NVUGIB between May 2002 and May 2013. Patients were divided into detection or non-detection groups according to the presence of bleeding stigmata in angiographic fi nding. Rebleeding defi ned as subsequent bleeding event within 7 days and mortality within 30days were analyzed as outcome parameters after TAE following detection in angiography. Results: A total 45 patients 37 (male, mean age, 65.9±14.9 years) were analyzed and classifi ed as a detection group (n=25, 55.5%) and non-detection group (n=20, 44.6%). Peptic ulcers were the most common cause of refractory NVUGIB. Larger transfusion amount (5.7±3.9 unit vs. 3.5±2.8 unit; P=0.03), prolonged aPTT level (34.2±17.3 sec vs. 21.8±13.8 sec; P=0.01) and short time interval between last endoscopy and angiography (17.5±25.9 hours vs. 34.3±59.5 hours; P=0.04) were found to be signifi cant factors for predicting angiographic detection. TAE was performed in all patients detected in angiography. Rebleeding (44%) was significantly associated with higher Rockall score (8.3±1.5 vs. 6.6±2.4; P=0.046) and mortality (12%) was signifi cantly associated with higher Rockall score (9.3±0.6 vs. 7.1±2.2; P=0.002) and higher level of BUN (55.3±47.4 vs. 27.6±17.4; P=0.01). Conclusions: Clinical characteristics associated with angiographic detection in patients with NVUGIB refractory to endoscopic therapy were severe bleeding, bleeding tendency and early angiographic intervention. The Rockall score is useful parameter for predicting rebleeding and mortality after TAE.

신라대학교 주변 백양산의 동물상

노치권(외 6명) 신라대학교 자연과학연구소 2012 自然科學論文集 Vol.22 No.-

To study fauna of Silla University located in Mt. Baek-yang, we conducted six surveys from 29 May 2011 to 28 April 2012. We found five phyla 41 orders 197 species of animals inhabiting in this area: four phyla 27 orders 163 species of invertebrates and in vertebrates one order six species of fishes, three orders nine species of amphibians and reptiles, six orders 14 species of aves, and four orders five species of mammals. Of these species, some Korean endemic species were included: a fish of Rhodeus uyekii in a pond near main gate of this university, a frog of Rana coreana in a creek near a dormitory, and a rabbit of Lepus coreanus and a water deer of Hydropotes inermis in a grass region near a main stadium. A kind of hawk, Falco tinnunculus as a natural monument (animal) of no. 323-8, was observed on a building of medical and life science. A blue frog of Hyla japonica as a variation was found near a spring resort. Therefore, this area is considered an ecologically important area having a high animal diversity.

고성능 액체 크로마토그라피에 의한 금은화 추출액중의 Chlorogenic acid의 정량

백승화,양태희 圓光大學校 基礎自然科學硏究所 1993 基礎科學硏究誌 Vol.12 No.1

The method for quantitative determination of chlorogenic acid in Lonicerac Flos extracts by high performance liquid chromatography(HPLC) was established. A reversed-phase system with a μ-Bondapak Cis column using methanol in 1.0% acetic acid (50 : 50) as a mobile phase was developed. Chlorogenic acid was detected at 280㎚ and the analysis was successfully carried out within 30 min.

냉기치료후 슬관절강내의 온도변화

백승석,최기섭,박시복,이상건,김영호,양길태,장윤희 大韓再活醫學會 1998 Annals of Rehabilitation Medicine Vol.22 No.2

[논문]여러 용매계에서 Poly(vinylidene fluoride) 의 물리적 젤화에 대한 동력학 및 열역학 연구

백승태,김봉수,이장우 釜山大學校生産技術硏究所 2006 生産技術硏究所論文集 Vol.65 No.-

Poly (vinylidene fluoride) (PVDF) 물리 젤은 각 기 다른 조 건 에 서 v-butyrolactone, cyclohexanone, propylene carbonate와 같은 다양한 유기용매에서 형성된다. 첼 녹는점은 시차주사열량계로 측정하였고 젤화 시간은 시험관 틸팅방법을 통해 측정하였다. 임계 젤 농도는 PVDF의 농도와 젤화 속도로 결정되어진다. 본 연구에서는 젤화 속도는 임계 농도를 얻기 위해 구하였다. 젤화 속도는 온도에 높게 의존한다; 젤화 속도는 젤화 시간의 역수로 분석 가능하며/ 젤화는 낮은 농도에서 투명한 젤이 형성되어지는 것과 젤 형성을 위한 엔탈피 변화가 적기 때문에 낮은농도에서 액-액 상분리에 의해 일어난다. 실온에서 천천히 건조시킨 젤 필름을 주사전자현미경으로 관측하였고 젤 필름에서 많은 구정과 연결 분자 들을 관찰하였다.

Guinea pig 단일 심실근 세포의 칼슘전류에 대한 아드레날린성 약물의 효과

백승곤,심태섭,방효원 중앙대학교 의과대학 의과학연구소 1991 中央醫大誌 Vol.16 No.4

In order to investigate the effects of sympathomimetic drugs on the calcium currents, whole cell patch clamp technique was used in ventricular cells of the guinea-pig. Single ventricular cells were isolated by Langedorff perfusion method with collagenase. T-type and L-type Ca-currents were recorded in different holding potentials. T-type Ca-current was activated from more negative membrane potentials(around -50 mV) and was inactivated very rapidly, whereas L-type Ca-current was activated from -30 mV and inactivated with two time constants(fast and slow components). Replacement of calcium with barium increased the activation magnitude of L-type Ca-current and delayed inactivation time course, but did not affect T-type Ca-current significantly. Nifedipine blocked and Bay K 8644 increased L-type Ca-current with voltage-dependent manner. T-type Ca-current, however, was relatively insentive to dihydropyridine compuonds. Isoproterenol which is known to have mainly beta-agonist increased L-and T-type Ca-currents and propranolol reversed the effect of isoproterenol. Phenylephrine(alpha-agonist) and phentolamine(alpha-blocker) have no significant effects on the Ca-currents. From the above results it is suggested that L-type and T-type Ca-currents are present in guineapig ventricular myocytes and very sensitive to beta-agonist or-antagonist, but relatively insensitive to drugs acting on alpha-receptors.

고삼 추출물을 이용한 해독물질의 개발

양희태,정승일,이영철,윤경아,백승화 한국식품영양학회 2002 韓國食品營養學會誌 Vol.15 No.1

고삼 메탄올 추출물로부터 분리한 flavonoids를 IR, NMR등의 분광학적인 방법으로 Leachianone A(LA)과 Sophoraflavanone G(SFG)로 동정하였고, 카드뮴의 세포독성효과를 고삼 및 고삼추출물이 방어할 수 있는 지를 검색하기 위하여 NIG 3T3 세포에 고삼 및 LA와 SFG, LA+SFG를 처리하고 MTT assay 및 광학현미경으로 세포의 생존률을 검색하여 다음과 같은 결론은 얻었다. MIT의 흡광도는 카드뮴의 농도에 의존하여 감소하였으며, IC_50인 MTT50은 12.5??이었으며 카드뮴을 IC_50농도로 처리하고 고삼 및 LA, SFG, LA+SFG를 각 화합물의 자체 세포독성을 갖지 않는 농도로 처리한 후 MTT assay로 세포 생존율을 측정한 결과 LA, SFG, LA+SFG 처리군들은 카드뮴 처리군(MTT_50)에 비해 세포생존률이 증가되었으며 이들은 고삼 및 고삼추출물의 농도에 의존적으로 증가되었고 각각의 단일 화합물보다 두 화합물 LA+SFG 병용처리군에서 수복 효과가 더 좋은 것으로 나타났으며 광학현미경적 소견에서도 세포재생이 뚜렷하게 보였다. 이상과 같이 고삼에서 분리한 flavonoids가 카드뮴 독성에 의하여 손상된 NIH 3T3 섬유아세포의 재생효과에 영향이 있는 것으로 판단된다. The aim of this study was to assess the antitoxic compounds, flavanones (Leachinanone A=LA and Sophora flavanone G=SFG), from Sophora flavescents (S. Flavescens). We investigated the possibility of antitoxicity of LA and SFG against NIH 3T3 fibroblasts cell lines using colorimetric MTT[3-(4-5-dimethylthiazol-2-yl)-2-5diphenyl-2H-tetra-azolium bromide] assay. The results were as follows : After cadmium was treated against NIH 3T3 cell lines, we determined IC_50. Accordingly we have examined the detoxification effects of S. flavescens, LA and SFG under cadmium IC_50=12.5?? and was carried out to observe morphological changes by the light microscopic study. In NIH 3T3 cells, Sophora flavescens, LA, SFG and LA+ SFG showed inhibitory effects on the cytotoxicity of cadmium and these detoxication effects increased in proportion to the concentration of these drugs. These results suggest that LA and SFG from S. flavescens retain a potential antitoxic activity.

암반사면의 안정을 위한 신뢰성 해석에 관한 연구

심태섭,기완서,주승완,백재상 朝鮮大學校 建設技術硏究所 2000 建設技術硏究 Vol.20 No.1

The stability of rock slope is mainly controlled by the engineering properties of discontinuities in the rock mass. Design method for deciding the cutting angle of rock slope must involve the significance of the mechanical and hydraulic characteristics of discontinuities on the shear strength of the rock mass. However most methods consider only rock strength as a prime factor for slope design, which sometimes result in failure. The optimum design of rock slope based on the limit equilibrium theory can vary significantly according to the mechanical characteristics of the discontinuities. Therefore, unless the level of ground water and its seasonal variations are accurately investigated, the reinforcements of any kind must be installed, besides the lowering of cutting angle, to ensure the stability of rock slope. This study is analyzed the stability of rock slopes by computing limit equilibrium theory. By analyzing probability of failure in rock slope, this study is analyzed the probability.

Nitinol 형상기억합금 전해가공의 전해액 영향분석

김백겸,신태희,백승엽,이은상 한국공작기계학회 2008 한국공작기계학회 춘계학술대회논문집 Vol.2008 No.-

Electro-chemical Machining, the anodic dissolution process is able to achieve wanted a sharp shape and high quality surface without contact with workpiece and low heat effect using electrochemical reaction between anode and cathode. In hence this process useful to apply micro structure. A shape memory alloy for micro-structure and micro industrial technique, Nitinol is composed of approximately 55% Nikel and 45% Titanium by weight. This material is able to function as to transform specific shape from a certain deformation when the alloy is heated. Therefore Nitinol is used for several industries such as a medical industry, a aerospace, electrical application on a part of micro structure. In this paper, effect of electrolyte is studied on electrochemical machining for Nitinol shape memory alloy, copper is used for electrode, diameter and depth are measured as a extent of processing using optical microscope.

21C 신지식인 양성을 위한 EQM 시스템 구축

최병태,이형민,전상봉,서승교,이우언,백종현 대구산업정보대학 2001 논문집 Vol.15 No.-

The aim of this paper is to form and to operate EQM, to say education quality management. In order to achieve the above stated purpose, the paper hypothesizes that there are similarities between enterprises and colleges in quality management. The basic method of the paper is systematic approach, modifies TQM, which is total quality management. The result is that EQM program must form and operate the feedback system for teaching and learning effect, the PSMT(project, self-study, media, team unit style teaching and learning) as a new teaching and learning method, and the digital system as an advanced mechanism, in education quality management.