뇌·심혈관질환 예방을 위한 사업장 지원 프로그램의 단기효과 분석

곽우석,원종욱,이정배,이명숙,강은주,노재훈 大韓産業醫學會 2009 대한직업환경의학회지 Vol.21 No.1

목적 뇌 심혈관질환은 주요한 사망원인이며 우리나라 산업재해 보상에 있어 중요 부분을 차지하고 있다 따라서 한국산업안전보건공단은 2000년도부터 지역 산업보건기관을 통해 많은 사업장에 뇌 심혈관질환 예방 프로그램을 지원해왔다 본 연구는 이 프로그램이 근로자의 뇌 심혈관질환 발병위험도 개선에 미치는 단기영향을 평가하고자 수행되었다 방법 2007년도 집중관리 프로그램 대상자 중 전후 발병위험도 평가가 가능했던 5,902명(53.3%)을 대상으로 혈압 콜레스테롤 비만도 및 발병위험도를 전후 비교하였다 발병위험도 평가는 KOSHA CODE H-11-2004 지침을 사용하였다 결과 평균 수축기 및 이완기 혈압이 4.9 mmHg 3.1mmHg 감소하였으며 총콜레스테롤과 비만도(BMI)는 각각 8.4 g/dL 0.1 kg/㎡ 감소하였다 흡연율은 6.0% 감소하였으며 규칙적인 운동 시행률은 23.1% 증가하였다 전체적인 발병위험도 개선율은 49.1%였다 결론 국가 지원의 뇌 심혈관질환 예방 프로그램은 단기적으로 좋은 성과를 나타냈다 향후 연구에서는 사업장 단위의 장기적인 영향과 비용-효과에 대한 분석이 이루어질 필요가 있다 Objectives Cardiovascular disease is the leading cause of death and a major source of workers' Compensation claims in Korea Since 2000 the Korea Occupational Safety and Health Agency (KOSHA), working through local occupational health institutions has supported cardiovascular disease prevention programs at a number of companies in Korea The purpose of this study was to assess the short term effects of this effort Methods A total of 11,077 workers at risk were enrolled in the workplace cardiovascular disease prevention program and 5,902 workers (53.3%) completed the 1-year course during 2007 The program consisted of a medical checkup and health counseling for the workers by occupational health nurses The guidelines for this prevention program were adopted from KOSHA Code H-11-2004 To determine the program's effectiveness the workers risks for cardiovascular disease were assessed before and one year after completion of the program Results The intervention led to significant reductions in the mean systolic and diastolic blood pressures of 4.9 mmHg and 3.1 mmHg respectively Mean total cholesterol and BMI were also reduced significantly by 8.4 g/dl and 0.1 kg/㎡ The rate of smoking was decreased by 6.0% and the percentage of workers engaging in regular exercise was increased by 23.1% of the 3,530 workers with the low risk and above the overall cardiovascular risk was improved in 1,734 (49.1 %) of them Conclusions The cardiovascular disease prevention program supported by the Korea Occupational Safety and Health Agency reduces cardiovascular diseases risks among workers and may improve the health status of workers in Korea

감염근관에서 Black-Pigmented Bacteria의 동정에 대한 연구

권은경,김은숙,곽주석,이황,이수종,임미경 大韓齒科保存學會 2002 Restorative Dentistry & Endodontics Vol.27 No.1

Black-pigmented bacteria have been implicated in the endodontic infections. This group of microorganisms includes Porphyromonass endodontalis, Porphyromonas gingicalis, Prevotella intermedia, and Prevotella nigresceus. The organisms display a wide variety of virulence factors that may be pertinent to acute endodontic infections. The aim of this study was to identify P.endodontalis, P.gingivalis, P.intermedia, and P.nigrescens by using special potency disk test, filter paper spot test, 16S rRNA gene-directed PCR, and API 32A. Microbial samples were collected from root canals of 33 intact teeth with necrotic pulp and/or apical periodontitis. Conventional laboratory methods were used for identification of the strains of black pigmented bacteria. Eighteen of 33 samples were positive for the growth of black-pigmented bacteria. Five colonies were cultured from each pure cultured colonies from Brucella agar plate. Seventy seven colonies were positive for the growth of black-pigmented bacteria. Thirty three of 77(42.6%) were identifed as P.nigrescens, 10 of 77(12.9%) were P.gingivalis, 6 of 77(7.8%) were P.endodontalis, 10 of 77(12.9%) were P.intermedia. On the contraty the reference strains of P.nigrescens, experimental strains of P.nigrescens was sensitive to kanamycin in special potency disk test. 16S rRNA gene PCR and API test after rapid presumptative identification methods. such as special potency disk test and filter paper spot test, would be accurate detection methods for black-pigmented bacteria.

Lutembacher 증후군 환자 증례 보고

김성범,서정주,곽철훈,김상민,이보라,민선경,황은구,김용인,조욱현,최석구 인제대학교 2008 仁濟醫學 Vol.29 No.-

Lutembacher's syndrome is rare combination of mitral stenosis (MS) and atrial septal defect (ASD). The hemodynamic interplay between the MS and ASD leads to wide variation of clinical presentation. Here we describe a 43-year-old female with Lutembacher's syndrome and tricuspid regurgitation with pulmonary hypertension, who underwent direct closure of ASD and tricuspid valvuloplasty successfully. We also reviewed other literatures in an effort to increase awareness of this condition.

한국 대도시 고령자의 체격, 체력 및 운동실태와 운동 프로그램개발에 관한 연구

김경지,강동원,장주호,전익기,윤우상,곽은창,박영진,유재충 경희대학교 사회체육연구소 1996 體育科學論叢 Vol.- No.9

The purpose of this study was to investigate the patterns of the health related variables, and physical characteristics and physical fitness of the elderly people in order to provide a exercise program. The data about the health related variables were collected through the personal interview, and the data about physical charateristics and physical fitness (height, weight, % body fat, blood pressure, pulse rate, grip stength, trunk flexion, side step test, 2 min, harvard step test) of 373 elderly people living Seoul and kyungkee area were collected. The conclusions of this study can be summarized as follow; 1. The test results about smoking, drinking, sleeping and self-evaluation of health revealed that the elderly people have self-confidence about their health. 2. Not many elderly people participate the proper exercise program even though they recognize the need of exercise. 3. The results showed that the elderly people do not pay much attention to the intensity of the exercise. 4. Muscle strength training for leg and the lower back and cardio-vascular endurance training was recommended to reduce the risk of varius problems caused by aging. 5. A exercise program was suggested for the elderly people.

Generation of bacterial blight resistance rice with OsNAC58-overexpressing

Eun-Shil Kwak,Ga-Hee Park,Duk-Ju Hwang,Il-Pyung Ahn,Shin-Chul Bae,Beom-Ki Kim,Sangryeol Park 한국육종학회 2013 한국육종학회 심포지엄 Vol.2013 No.07

Plant specific gene family, NAC (NAM, ATAF, and CUC) transcription factors have been characterized for their roles in plant growth, development, and stress tolerance. In this study, we isolated OsNAC58 gene from rice and analysed expression level by inoculation of bacterial leaf blight pathogen, Xanthomonas oryzae pv. oryzae (Xoo). NAC transcription factor family can be divided into five groups (I–V). On the basis of phylogenetic analysis, OsNAC58 was fall into group III. 35S::OsNAC58-GFP fusion protein was localized on the nuclei. To investigate its biological function in the rice, we constructed vector for overexpression in rice, and then generated transgenic rices. Gene expression of OsNAC58-overexpressed transgenic rice lines were analyzed by northern blot. Analysis of disease resistance to pathogen Xoo, twelve OsNAC58-overexpressed transgenic rice lines showing high expression level of OsNAC58 were shown more resistant than wild type. These results suggest that OsNAC58 gene may play regulatory role during pathogen infection.

The Relationship among Good Death Perception, Attitudes toward Advanced Directives and Attitudes toward Euthanasia in Nursing Students

Eun-Ju Kwak 한국간호과학회 2021 한국간호과학회 학술대회 Vol.2021 No.10

Aim(s): This study amis to identify the relationship among good death perception, attitude toward advanced directives and attitude toward euthanasia in nursing students. Method(s): The participants of this study were nursing students from two Nursing Universities located in Seoul and Chungcheongnam-do. The number of subjects required for this study was 152 when calculated using the G power 3.1 program, with a significance level of α = .05, a medium effect size of .15, a power of .90, and 11 factors. It was calculated. A 10% dropout rate was considered, and 170 subjects were surveyed to increase statistical reliability. Data were analyzed using frequency, percentage, T-test, Pearson"s correlation, and multiple regression analysis. Result(s): There was a positive correlation between the perception of good death and their attitude toward advanced directives (r = .380, p <.001). There was a positive correlation between the perception of good death and their attitude toward euthanasia (r = .269, p <.001). The presence of good death (β = .384) and death-related education experience (β = .172) demonstrated positive influence on attitude toward advanced directives (F = 11.65, p <.001). Awareness of good death (β = .270) and not having religion (β = .207) demonstrated influence on attitude toward euthanasia (F = 10.84, p <.001). Among the general characteristics, the presence or absence of death-related educational experience showed a significant difference in the attitude toward the advance directive, and the presence or absence of religion showed a significant difference in the attitude toward euthanasia. It was found that the perception of a good death had an effect on the attitude toward advance medical directive and the attitude toward euthanasia. Conclusion(s): From the above results, it is important for nursing students to work in the field of end-of-life care in the future, so it is important to raise awareness of the good death. For this, the development of a systematic and standardized curriculum is recommended.

Free Paper Session : Basic ; C-reactive protein enhances cell proliferation and protects from apoptosis in hepatocellular carcinoma cells (초)

( Eun Ju Cho ),( Jung Hwan Yoon ),( Eun Sun Jang ),( Min Sun Kwak ),( Su Jong Yu ),( Jeong Hoon Lee ),( Yoon Jun Kim ),( Hyo Suk Lee ),( Chung Yong Kim ) 대한간학회 2011 Clinical and Molecular Hepatology(대한간학회지) Vol.17 No.3(S)

Charactrization of OsNAC69 gene related to bacterial leaf blight resistance

Eun-Shil Kwak,Eun-Mi Cha,Duk-Ju Hwang,Il-Pyung Ahn,Shin-Chul Bae,SangRyeol Park 한국육종학회 2012 한국육종학회 심포지엄 Vol.2012 No.07

Plant specific gene family, NAC (NAM, ATAF, and CUC) transcription factors have been characterized for their roles in plant growth, development, and stress tolerance. In this study, we isolated OsNAC69 gene and analysed expression level by inoculation of bacterial leaf blight pathogen, Xanthomonas oryzae pv. oryzae (Xoo). NAC transcription factor family can be divided into five groups (I–V). On the basis of phylogenetic analysis, OsNAC69 was fall into group II. OsNAC69 was strongly induced 1 hr after infected with Xoo. To investigate its biological function in the rice, we constructed vector for overexpression in rice, and then generated transgenic rices. Gene expression of OsNAC69-overexpressed transgenic rice lines were analyzed by northern blot. Analysis of disease resistance to pathogen Xoo, nine OsNAC69-overexpressed transgenic rice lines showing high expression level of OsNAC69 were shown more resistant than wild type. These results suggest that OsNAC69 gene may play regulatory role during pathogen infection.

Hepatitis B : Comparison of prophylactic and therapeutic antiviral strategy in HBsAg-positive kidney allograft recipients (초)

( Eun Ju Cho ),( Jeong Hoon Lee ),( Eun Sun Jang ),( Min Sun Kwak ),( Su Jong Yu ),( Yoon Jun Kim ),( Jung Hwan Yoon ),( Hyo Suk Lee ),( Chung Yong Kim ) 대한간학회 2011 Clinical and Molecular Hepatology(대한간학회지) Vol.17 No.3(S)

공학계열 여학생의 교수 및 교우와의 상호작용 유형과 예측요인

곽은주(Kwak, Eun Ju),배상훈(Bae, Sang Hoon) 학습자중심교과교육학회 2019 학습자중심교과교육연구 Vol.19 No.18

본 연구의 목적은 공학계열 여학생들이 경험하는 교수 및 교우와의 상호작용 양상을 유형화하여 몇 개의 하위 집단으로 나누고, 각 집단별로 교수 및 교우와의 교류면에서 나타나는 특징을 탐색하고자 하였다. 또한 본 연구는 학생 개인 특성과 대학 특성이 각 집단을 구분하는데 어떠한 영향을 미치는지도 살펴보았다. 연구 대상은 전국 85개 대학에 재학 중인 공학계열 여학생 4,481명이다. 연구 목적을 달성하기 위해 잠재프로파일 분석과 로지스틱 회귀분석을 수행하였다. 연구 결과, 교수 및 교우 와의 상호작용을 기준으로 세 가지 하위 집단이 나타났다. 각 집단에 대해서 ‘낮은수준의 상호작용 집단’, ‘중간 수준의 상호작용 집단’, ‘높은 수준의 상호작용 집단’으로 명명하였다. 전체 표본의 절반 정도가 교수 및 교우와 낮은 교류를 하는 집단에 속하는 것으로 나타났다. 둘째, 학생 개인 특성에서는 학년, 전공 만족도, 대학 몰입이, 대학 특성으로는 대학의 소재지가 준거 집단인 ‘높은 수준의 상호작용 집단’과 다른 2개 집단을 구분하는 데 유의하게 영향을 미치는 변인으로 나타났다. 특히 수 도권 대학과 비교해서 지방대학 공학계열에 재학하는 여학생일수록 교수 및 교우와의 상호작용이 낮을 가능성이 더욱 크다는 점이 발견되었다. 마지막으로 본 연구는 이상의 결과를 토대로 정책적 시사점을 제시하였다. This study intended to identify the different patterns of female students’ interaction with the faculty and their peers in the engineering college. In addition, the study investigated whether the patterns could be differentiated in terms of individual and the university related variables. The study used the data from 2015 Korean-National Survey of Student Engagement(K-NSSE). Samples include 4,481 female students in engineering. Data were analyzed using latent profile analysis(LPA) to identify different patterns of the interaction with the Faculty members and Peers. Multinomial logistic regression analysis was employed to examine the influence of the predictors to the classification among latent classes. The study results may be summarized as follows. First, the patterns of female students’ interaction with professors and peers were classified into three potential classes. They include ‘low-level interaction group’, ‘middle-level interaction group’ and ‘high-level interaction group’. Second, 55.8% of samples were found to belong to the low level interaction group. Third, the characteristics of the individual students such as grade, satisfaction on the major, and institutional committment were found to be related to group classification. At the university level, the location of the institution were found to affect the classification of the group. The study results suggest that female engineering students may feel the ‘chilly climate’ at the university campus in terms of human environments. It may be imperative that local universities need to make more efforts to change campus environments into more female-friendly campus environment.