족관절 삼과 골절에서 작은 후과 골편에 대한 나사못 고정과 비고정의 결과 비교

고지욱 ( Jee-wook Ko ),이건우 ( Gun-woo Lee ),이근배 ( Keun-bae Lee ) 대한골절학회 2021 대한골절학회지 Vol.34 No.1

목적: 족관절 삼과 골절에서 관절면의 25% 이내를 침범하는 작은 후과 골편에 대한 나사못 고정술 여부에 따른 결과를 비교하고자 하였다. 대상 및 방법: 후과 골편이 관절면의 15%-25%를 침범한 총 32예(32명)를 대상으로 내고정 여부에 따라 두 군(고정군 20예, 비고정군 12예)으로 분류하였으며, 최소 추시 기간은 12개월이었다. 고정군과 비고정군에서 후과 골편 크기의 중앙값은 각각 24.6% (범위 22.3%-25.0%)와 22.1% (범위17.4%-24.3%)였다. 두 군 간의 임상적 및 방사선적 결과를 비교 분석하였다. 결과: 최종 추시상, 두 군 간 AOFAS ( p=0.501), VAS (p=0.578), 족관절 운동 범위(p=0.552) 등의 임상적 결과의 차이는 없었다. 방사선적 분석 결과로 두 군 간 관절면 층 형성(p=0.289), 골편 간극(p=0.289)의 차이는 없었다. 합병증은 고정군에서 지연 유합이 1예, 창상 감염이 1예 있었다. 결론: 족관절 삼과 골절에서 작은 후과 골편에 대한 나사못 고정군과 비고정군은 모두 만족스러운 결과를 보여주었다. 따라서, 작은 후과 골편을 동반한 경우 관절면의 정복이 이루어진다면 추가적인 내고정술을 시행하지 않더라도 만족할만한 결과를 얻을 수 있을 것으로 생각한다. Purpose: This study was undertaken to compare outcomes of screw fixation and non-fixation of a small-sized posterior malleolar fragment involving less than 25% articular surface in ankle trimalleolar fractures. Materials and Methods: A total of 32 consecutive ankles (32 patients), with posterior malleolar fragment involving 15%-25% of the joint surface, were enrolled in the study. Patients were divided into 2 groups according to whether the fragment was fixed or not (fixed: 20 ankles, non-fixed: 12 ankles). The minimum follow-up period was 12 months. Median size of the posterior malleolar fragment in the fixed and non-fixed groups were 24.6% (range, 22.3%-25.0%) and 22.1% (range, 17.4%-24.3%), respectively. Complications as well as clinical and radiographic outcomes were compared and analyzed between the two groups. Results: Clinical outcomes, including American Orthopaedic Foot & Ankle Society (p=0.501), visual analogue scale (p=0.578), and ankle range of motion (p=0.552), showed no difference between groups at the final follow-up. No differences were obtained in the radiographic outcomes, including joint stepoff (p=0.289) and fragment gap (p=0.289). Complications, including 1 case of delayed union and 1 case of wound infection, were reported in the fixed group. Conclusion: Clinical outcomes and radiographic outcomes of the non-fixation group were satisfactory and comparable to the fixation group. Our results indicate that anatomical reduction with small-sized posterior malleolar fragment in ankle trimalleolar fractures is sufficient for satisfactory outcomes, without the need for additional internal fixation.

The Analysis of Risk Factors in No Thumb Test in Total Knee Arthroplasty

Jee Hyoung Kim,Song Lee,Dong Oh Ko,Chang Wook Yoo,Tae Hwan Chun,Jung Soo Lee 대한정형외과학회 2011 Clinics in Orthopedic Surgery Vol.3 No.4

Background: We would like to analyze the risk factors of no thumb test among knee alignment tests during total knee arthroplastysurgery. Methods: The 156 cases of total knee arthroplasty by an operator from October 2009 to April 2010 were analyzed according topreoperative indicators including body weight, height, degree of varus deformity, and patella subluxation and surgical indicatorssuch as pre-osteotomy patella thickness, degree of patella degeneration, no thumb test which was evaluated after medial prepatellaincision and before bone resection (1st test), no thumb test which was evaluated with corrective valgus stress (2nd test, Jtest), and the kind of prosthesis. We comparatively analyzed indicators affecting no thumb test (3rd test). Results: There was no relation between age, sex, and body weight and no thumb test (3rd test). Patellar sulcus angle (p = 0.795),patellar congruence angle (p = 0.276) and preoperative mechanical axis showed no relationship. The 1st no thumb test (p = 0.007)and 2nd test (p = 0.002) showed signifi cant relation with the 3rd no thumb test. Among surgical indicators, pre-osteotomy patellathickness (p = 0.275) and degeneration of patella (p = 0.320) were not relevant but post-osteotomy patellar thickness (p = 0.002)was relevant to no thumb test (3rd test). According to prosthesis, there was no signifi cance with Nexgen (p = 0.575). However,there was signifi cant correlation between Scorpio (p = 0.011), Vanguard (p = 0.049) and no thumb test (3rd test). Especially, Scorpiohad a tendency to dislocate the patella, but Vanguard to stabilize the patella. Conclusions: No thumb test (3rd test) is correlated positively with 1st test, 2nd test, and post-osteotomy patella thickness. Therefore, the more patella osteotomy and the prosthesis with high affi nity to patellofemoral alignment would be required for correctpatella alignment.

Production of Human Serum Albumin in Chloroplast-Transformed Tobacco Plants

Ko, Suk-Min,Kim, Hyun-Chul,Yoo, Byung-Ho,Woo, Je-Wook,Chung, Hwa-Jee,Choi, Dong-Woog,Liu, Jang-R. The Korean Society of Plant Biotechnology 2006 식물생명공학회지 Vol.33 No.4

Human serum albumin (HSA) is the most abundant protein in plasma and is the most often used intravenous protein in many human therapies. However, HSA is currently extracted only from plasma because commercially feasible recombinant expression systems are not available. This study attempted to develop an efficient system for recombinant HSA production by chloroplast transformation of tobacco. A HSA cDNA was isolated from a cDNA library constructed with human liver tissue. Chloroplast transformation vectors were constructed by introducing various regulatory elements to HSA regulatory sequences. Vectors were delivered by particle bombardment into leaf explants and chloroplast-transformed plants were subsequently regenerated into whole plants. Southern blot analysis confirmed that the HSA cDNA was incorporated between rps12 and orf70B of the chloroplast genome as designed. Western blot analysis revealed that hyper-expression and increasing the stability of HSA were achieved by modification of the regulatory sequences using the psbA5'UTRs in combination with elements of the 14 N-terminal amino acids of the GFP and the FLAG tag. However, only plants transformed with the vector containing all of these elements were able to accumulate HSA.

차조 품종별 오메기떡 이화학적 특성 및 항산화활성

고지연, 우관식, 이재생, 정태욱, 윤영호 忠北大學校 農業科學硏究所 2014 農業科學硏究 Vol.30 No.2

This study was conducted to investigate the quality characteristics and antioxidant activities of Omegidduk by glutinous foxtail millet varieties for evaluation optimum foxtail variety. The tested varieties for Omegidduk were Samdachal, Kyeonggwan 1, Kyeonggwan 2, and waxy rice as control. The contents of protein, crude fat, ash and mineral components of Omegidduk made by glutinous foxtail millet varieties were higher than those of waxy rice regardless of varieties. Glutinous foxtail millet Omegidduk were increased by protein content 1.3~1.5 fold, crude ash 12.4~14.0 fold, calcium 1.6~2.0 fold, and magnesium 5.3~8.6 fold than waxy rice Omegidduk. The contents of polyphenol and flavonoid of Omegidduk made by Samdachal, Kyeonggwan 1, and Kyeonggwan 2 were increased by 3.8~6.5 fold, and 3.2~5.3 fold. ABTS and DPPH radical scavenging activities of Omegidduk made by glutinous foxtail millet varieties were increased by 11.6~19.0 fold and 48.0~75.6 fold, respectively, compared to waxy rice that. Among the foxtail millet varieties, all the investigated components of Samdachal Omegidduk were higher than Kyeonggwan 1, and Kyeonggwan 2. The color values of Omegidduk among treatments, Samdachal Omegidduk showed the lowest L-value and b-value. As the results, Samdachal was evaluated as the most suitable glutinous foxtail millet variety in the view of quality characteristics and antioxidant activities.

적혈구 증다증의 임상적 고찰

한지숙,이선주,남동기,강신욱,고윤웅 大韓血液學會 1990 大韓血液學會誌 Vol.25 No.1

조 혼합비율별 오메기떡 품질특성 및 항산화활성

고지연, 우관식, 이재생, 정태욱, 윤영호 忠北大學校 農業科學硏究所 2014 農業科學硏究 Vol.30 No.2

This study was conducted to investigate the quality characteristics and antioxidant activities of Omegidduk by addition ratio of glutinous foxtail millet ‘Samdachal’ and waxy rice. The tested treatments of added ratio of ‘Samdachal’ in waxy rice dough were 0%, 10%, 30%, 50%, 70% and 100%. The contents of protein, crude fat, ash and mineral components in Omegidduk made by glutinous foxtail millet ‘Samdachal’ were higher than waxy rice one as addition amounts of ‘Samdachal’ were increased. The contents of polyphenol, flavonoid, ABTS and DPPH radical scavenging activities of Omegidduk were the same tendency. The color values of Omegidduk by treatments decreased L-value and b-value as added amounts of ‘Samdachal’ in waxy rice were increased and the Omegidduk by treatments showed the characteristics of ‘Samdachal’ color after 30% added. The Hardness of Omegidduk of just after processing were similar between treatments, but those showed higher values by addition ratio of ‘Samdachal’ increasing after defrost. In sensory evaluation of Omegidduk treatments, the addition of over 70% of ‘Samdachal’ in Omegidduk were showed lower value in overall acceptability. As the results, 30~50% of addition of glutinous foxtail millet ‘Samdachal’ in the view of heathy function and overall acceptability.

Effects of Physicochemical Characteristics of Different Milling Type Sorghum (Sorghum bicolor L. Moench) Tea According to Pan-fried Times

Jee Yeon Ko,Koan Sik Woo,Seuk Bo Song,Hyun Young Kim,Hye In Seo,Jung In Kim,Jae Saeng Lee,Tae Wook Jung,Ki Young Kim,Do Yeon Kwak,In Seok Oh,Heon Sang Jeong 한국식품영양과학회 2012 한국식품영양과학회 학술대회발표집 Vol.2012 No.10

공사비 절감을 위한 공동주택 건축물에너지효율등급 인증 최적설계지침 가이드라인 연구

고종철(Ko, Jong-Chul),이종인(Lee, Jong-In),김현배(Kim, Hyun-Bae),신지웅(Shin, Jee-Woong),고정림(Ko, Jung-Lim),안병욱(An, Byung-Wook),강승구(Kang, Seung-Ku) 한국건축친환경설비학회 2012 한국건축친환경설비학회 학술발표대회 논문집 Vol.2012 No.10

In the present day, the international society is promoting policies to reduce greenhouse gas emission. In Korea, buildings consume over 25% of the total energy consumed. Contribution rates are applied in order to draw the utmost measures to reduce building energy consumption. In comparison to total construction cost, insulation is studied to yield the most contribution toward energy reduction. Heating method and glazing were the next. By applying the certification system, additional construction cost is about ￦700,000∼￦1,400,000 when upgrading level. Finally, the construction cost is going to add ￦30,000∼180,000 per 1% of energy saving. The insulation has highest efficiency among other materials used in the construction.

수수겨 분말 및 추출물 첨가가 유과의 품질특성 및 항산화활성에 미치는 영향

고지연(Jee Yeon Ko),우관식(Koan Sik Woo),김정인(Jung In Kim),송석보(Seuk Bo Song),이재생(Jae Saeng Lee),정미선(Mi Seon Jeong),정태욱(Tae Wook Jung),윤영호(Young Ho Yun),오인석(In Seok Oh) 한국식품영양과학회 2014 한국식품영양과학회지 Vol.43 No.8

수수의 건강기능성을 산업적 측면에서 더욱 효과적으로 이용하기 위하여 수수 품종 중 항산화활성이 높은 ‘동안메’에서 활성이 가장 높은 부위인 수수겨가 첨가된 유과의 이화학적 특성 변화를 평가하여 ‘동안메’ 수수겨 첨가에 의한 기능성 증진 및 산패 억제 효과를 검토하고자 본 시험을 수행하였다. ‘동안메’ 수수겨 분말을 주정 100%로 추출한 뒤 동결건조를 통해 농축시킨 추출물과 수수겨 분말 자체를 찹쌀유과반대기에 첨가하였는데, 처리 수준은 수수겨 분말 1%, 5%로, 수수겨 추출물 0.1%, 0.5%, 1% 및 대조(찹쌀 100%)로 하였다. 유과의 단백질, 회분 및 무기성분 함량은 ‘동안메’ 겨 추출물 및 대조구에 비하여 겨 분말의 첨가 시 증가하는 경향이었으며, 항산화성분인 유과 중 flavonoid 함량은 대조구에 비하여 ‘동안메’ 겨 수수겨 1, 5% 및 수수겨 추출물 0.1, 0.5, 1% 첨가 시 1.6∼17.1배, ABTS와 DPPH 라디칼 소거능은 각각 1.8∼7.4배, 2.3∼13.6배 증가하였다. 가장 높은 항산화성분 및 활성을 나타낸 것은 ‘동안메’ 수수겨추출물 1%가 첨가 시이며, 다음으로 겨 분말 5%, 겨 추출물0.5%, 겨 분말 1%, 겨 추출물 0.1%의 순이었다. 색도와 팽화도로 유과의 품질 변화를 살려본 결과 수수겨가 첨가된 유과반대기 및 튀겨진 유과의 색도는 첨가물 함량이 증가할수록 명도는 감소하고 적색도 및 황색도는 증가하였으며, 팽화도는 수수겨 분말 1%, 수수겨 추출물 0.1%, 0.5%가 첨가된 경우 대조구와 크게 차이가 없었으나 수수겨 분말5%, 수수겨 추출물 1% 첨가 시 현저히 감소되었다. 관능평가에서 전체적인 기호도는 팽화도와 마찬가지로 수수겨5%, 수수겨 추출물 1% 첨가 시 현저히 감소하였으며 수수겨 추출물 0.5%를 첨가한 처리에서 가장 높게 나타나, 수수겨 분말 1%, 수수겨 추출물 0.1∼0.5% 첨가로는 기호성에 나쁜 영향을 미치지 않는 것으로 나타났다. 또한 수수겨 가루 및 추출물이 첨가된 유과의 고온저장 중 산가 및 항산화활성 변화를 살펴본 결과 저장 20일부터 산가가 급격히 증가하였으며 대조구의 산가가 높게 나타나고 수수겨 분말 첨가 시 증가가 완만히 일어나는 경향이었다. ABTS 라디칼소거능은 산가와는 달리 저장기간의 경과에 따라 변화가 크게 나타나지 않았으며, 처리별로는 초기의 항산화활성 차이가 35일까지 계속 유지되는 것으로 나타났다. 결론적으로 항산화성, 산가 변화 및 유과의 품질특성 등을 고려할 때 ‘동안메’ 수수겨는 분말로서 1%, 추출물로서 0.5% 미만으로 유과에 첨가하는 것이 바람직한 것으로 판단되었다. This study investigated the quality characteristics and antioxidant activities of Yukwa added with ‘Donganme’ sorghum bran powder and its extracts. ‘Donganme’ variety has the highest antioxidant activity among sorghum varieties in Korea. The added contents of sorghum bran to Yukwa were 1% and 5% bran powder of ‘Donganme’ (BPD 1% and 5%) as well as 0.1%, 0.5%, and 1% bran powder extracts of ‘Donganme’ (BED 0.1%, 0.5%, and 1%). The contents of protein, ash, and minerals of BPD 1% and 5% added Yukwa were higher compared to non-added and BED 0.1%, 0.5%, and 1% added Yukwa. The contents of flavonoids of BPD 1% and 5% as well as BED 0.1%, 0.5%, and 1% added Yukwa increased by 1.6~17.1 fold, and DPPH and ABTS radical scavenging activities increased by 1.8~7.4 fold and 2.3~13.6 fold, respectively, compared to non-added Yukwa. Yukwa added with BED 1% showed the highest antioxidant activity among the treatments, followed by BPD 5%, BED 0.5%, BPD 1%, and BED 0.1% added Yukwa. The expansion ratios of BPD 5% and BED 1% added Yukwa remarkably decreased compared to those of non-added and other treatments. The sensory evaluation values corroborated the results of the Yukwa expansion ratio. The acid values of Yukwa under high temperature storage (60±1°C) increased rapidly after 20 days in all treatments, and those of BPD 5% and 1% added Yukwa increased slowly compared to non-added Yukwa. ABTS radical scavenging activities of Yukwa showed little change during storage in all treatments. As a results, addition of sorghum bran below BPD 1% and BED 0.5% was suitable for antioxidant activity, quality characteristics and sensory evaluation.

N Use Efficiency and Nitrate Leaching by Fertilization Level and Film Mulching in Sesame Cultivated Upland

Dong-Wook Lee,Ki-Do Park,Chang-Young Park,Il-Soo Son,Ui-Gum Kang,Jee-Yeon Ko,Kang-Bo Shim,Young-Son Cho,Sung-Tae Park 韓國作物學會 2007 Korean journal of crop science Vol.52 No.3

This study was conducted to evaluate the effect of slow release fertilizers (SRF), crotonylidene diurea (CDU) and latex coated urea (LCU), on nitrogen (N) use efficiency (NUE) and nitrate-N leaching in a silty clay loam soil under polyethylene film mulching (PFM) for sesame cultivation. In PFM plot, concentrations of NO3-N and NH4-N in SRF applied soils were less than that in the urea plot during the whole growing period. However, NO3-N and NH4-N in all the non-mulched plots (NM) were not significantly different. Urea-N in soil treated with SRF was higher than urea plot until 50 days after application and was comparable in all the treatments after 50 days. NO3-N concentrations in leached solution in 21 days after urea fertilization in PFM and NM were 26 mg L-1 and 83 mg L-1 , respectively. However, NO3-N in leached solution at applied CDU and LCU was less than that of urea similar to nitrate concentration in soil. NO3-N in leached solution in applied CDU and LCU in 44 days after application was about 25% lower than that urea plot and PFM, while the NO3-N concentration of CDU and LCU treatment in NM did not changed. Application of SRF increased the yield of sesame and N recovery compared to urea and there was a little difference between SRF and N levels. In conclusion, application of 80% N level with SRF increased N recovery and reduced nitrate leaching without reduction of yields compared with urea application.