소아청소년과의사의 영유아기 구강건강 관리에 대한 인식도 조사

주태준,박호원,이주현,서현우 大韓小兒齒科學會 2009 大韓小兒齒科學會誌 Vol.36 No.3

국민건강보험공단에서 실시하는 영유아 건강검진은 5회의 일반검진과 2회의 구강검진으로 구성되어 있다. 하지만 9개월 영유아 건강검진 시 구강건강 상담 및 교육은 일반의사가 담당하도록 되어 있어 이를 주로 담당하게 될 소아청소년과의사의 구강건강 상담 항목에 대한 지식이 필요한 상황이다. 이번 조사의 목적은 소아청소년과 전문의나 전공의를 대상으로 영유아기 구강건강교육에 대한 인식도를 알아보는 것으로 150명의 설문을 분석해 다음과 같은 결론을 얻었다. 1. 조사 대상자의 대부분은 유아기우식증으로 인한 치과 의뢰 경험이 있었고, 절반 이상의 응답자는 영유아 환자에 대해 구강검사를 시행하지 않고 있었다. 2. 조사 대상 소아청소년과의사들의 첫 치과방문 시기에 관한 적절한 인식도가 확립되지 않았다. 3. 영유아 건강검진 중 구강건강 교육 항목에 대한 인지도가 전반적으로 부족하였다. 이에 대한 교육의 강화가 필요하다. 4. 영유아 구강질환 예방을 위한 의과계의 관심과 더불어 치과계와의 협조가 필요하리라 생각 된다. For prevention of ECC, the Korean Academy Of Pediatric Dentistry(KAPD) advocate that Children should be seen as early as 6 months of age after the first tooth erupts, or 12 months of age. Pediatrics have increased access to new mothers and children 6 to 12 months while dentists does not see young children unless there are urgent problems. Therefore, they have an opportunity to impact infant oral health care. This study's purpose was to examine pediatricians' awareness and experience about infant oral health care. For the study, we surveyed of 150 pediatricians in korea. The survey comprised 10 questions related to infant oral health care and the recommended age a child go for their first dental visit. The results were as follows: 1. Most respondents had been referred children to a dentist for treating ECC and more than half of respondents reported that they did not do oral examination in their practice. 2. The majority of surveyed pediatricians are not advising patients to see the dentist by 1 year of age. 3. The surveyed pediatrician's awareness of infant oral health care is insufficient. The oral health education should be reinforced. 4. There is a need for increased infant oral health care education in the medical and dental communities.

Formocresol pulpotomy와 연관된 함치성 낭종의 시험례

주태준,박호원,이주현,서현우 大韓小兒齒科學會 2009 大韓小兒齒科學會誌 Vol.36 No.3

1904년 Buckley에 의해 치근관 살균제로 도입된 이후로 1:5로 희석된 formocresol을 사용한 치수절단술이 치아우식에 의한 유치의 비가역적 치수염시에 가장 많이 사용되어 왔다. Formocresol은 치수조직의 높은 고정능력으로 높은 임상적 성공률을 보이고 있으나 자체독성이 매우 강하여 영구 계승치 치배의 변위나 결손, 법랑질 형성 부전, 전신흡수로 인한 돌연변이 가능성과 암유발 가능성 역시 보고되고 있다. 또한 formocresol을 사용한 치수절단술 후에 과사용된 formocresol에 의한 만성적인 염증이 계승 영구치로 확산되어 퇴축법랑상피의 증식을 자극하고 법랑질로부터 퇴축법랑상피를 분리시켜 함치성 낭종을 형성할 수 있음이 보고되고 있다. 본 증례는 3년 전 응급으로 하악 좌측 제 2유구치의 formocresol을 사용한 치수절단술 후 정기 검진을 위해 내원한 환자의 방사선 사진에서 함치성 낭종이 발견되어 낭종 제거와 함께 유치의 발치를 시행했고 발치된 유치에서 formocresol cotton pellet이 제거되지 않은 채로 발견되어 formocresol이 장기간 남아있음으로 인해 낭종을 형성할 수 있음을 보고하는 바이다. Buckley's formocresol was first introduced as a pulp medicament in 1904, and since 1930, it has been the treatment of choice for primary molar pulpotomies. Formocresol has fixation effect of pulp tissue and high clinical success rate. But side effect such as displacement and loss of permanent successor, amelogenesis imperfecta, cyst formation, mutation by general absorption, possibility of cancer induction have been reported. Of those, dentigerous cyst can form in the periradicular region after formocresol pulpotomy caused by an alteration of the reduced enamel epithelium, which result in fluid accumulation between the epithelium and the tooth crown. The present case describes a 6-year-old girl who had accidentally discovered in the panoramic radiograph a single, well-defined, radioluscent area enclosing the second unerupted mandibular premolar. The second left primary molar had been pulpotomizied 3 year before. Surgical treatment was carried out, the primary molar was extracted and cystectomy was performed under local anesthesia. In the extracted second primary molar, formocresol cotton pellet was left in the pulp chamber. Histologic study confirmed the suspected diagnosis of dentigerous cyst. This report present a case of dentigerous cyst associated with inadequate formocresol pulpotomized deciduous molar.

프롤린 함량 증가 및 내건성 강화 관련 새로운 RING-Type E3 유비퀴틴 리가아제 애기장대 atrzf1 돌연변이체의 생리적 기능 연구

주현우,민지희,정문수,김철수 전남대학교 농업과학기술연구소 2021 농업생명과학연구동향 Vol.59 No.-

The covalent attachment of ubiquitin to proteins plays a fundamental role in the regulation of cellular function through biological events involving abiotic of biotic stress responses, immune responses, and apoptosis, Here, we characterize the biological function of the Arabidopsis thaliana RING Zinc Finger 1 (AtRZF1) in dehydration response. AtRZF1 was significantly reduced by drought stress. The atrzf1 mutant was less sensitive to osmotic stress than the wild-type during early seedling development, wheareas transgenic pants overexpressing AtRZF1 were hypersensitive, indicating that AtRZF1 megatively regulates drought-mediated control of early seedling developmeng. Moreover, the ectopic expression of the AtRZF1 gene was very significantly influential in drought sensitiv parameters including proline content, water loss, membrance ion leakage and the expression of dehy-dration stress-relat genes. ARZF1 is a functional E3 ubiquitin ligase, and its conserved C3H2C3-type RING domain is likely important for the biological function of AtRZF1 in drought response. Together, these results suggest that the E3 ligase AtRZF1 is an important regulator of water deficit stress during early seedling development.

활성탄 제조용 하수슬러지 활성탄화로 개발

정동현,이우주,전영남 조선대학교 환경공해연구소 2007 環境公害硏究 Vol.20 No.1

Sludge treatment has been studied with many researcher since disposal problem of sewage sludge was became powerfully. But there was still the problem of secondary pollution and heavy metal leaching in the sewage sludge treatment process. To solve the problem, the treatment was to produce active carbon through the carbonization and the steam activation. In this study attempts to optimum design a activated carbonizer and optimum operation conditions and the technology as changing the variables. parametric screening studies were carried out for variations of the following variables : input of steam "10∼80 g/min" and carbonized time "12∼31.2 min". At the result of this is chosen, that input of steam "35 g/min" and carbonized time "31.2 min". At this time, Iodine adsorptivity and output particle diameter shown that 245.5 ㎎/g and under 4 mm. And also, by using photograph and SEM were confirmed the pore development.

공구형상이 칩유동에 미치는 영향에 관한 연구

김경우,김우순,윤주식,채왕석,김동현 한국공작기계학회 2000 한국공작기계학회 추계학술대회논문집 Vol.2000 No.-

A new methodology is presented to evaluate material properties at high strain rates and high temperatures based on orthogonal metal cutting experiments and FEM simulations. Average strain rate and average temperature found in the deformation zone are computed and flow stress data at these conditions are modified until cutting forces calculated in simulations match those determined in experiments. Material properties obtained from this method were verified by additional metal cutting simulations. Derivation from cutting forces measured in experiments was less than 10%. The feasibility of tool design using FEM simulations is also demonstrated.

디지털 설계에 적합하도록 수정된 Anti-cloche 필터를 가진 디지털 SECAM encoder의 설계

이민우,김주현,강봉순 東亞大學校附設情報技術硏究所 2005 情報技術硏究所論文誌 Vol.12 No.2

This paper presents a new design method of Sequentiel Couleur Avec Memoire (SECAM) which is one of the normal broadcasting standards. The analog SECAM encoder is difficult to make a digital hardware because of a characteristic of Anti-cloche filter, pre-emphasis filter and FM modulation. So this paper proposes the modified filter and the rearranged FM modulation method for digital SECAM encoder. The proposed method makes it possible that the SECAM encoder can be implemented by a digital system like as National Television Standards Committee (NTSC) and Phase-Alternate Line (PAL).

Dextranase 함유 구강 세정액의 치태 제거 및 치은염 예방 효과에 관한 임상적 연구

송우성,손성희,정현주 전남대학교 치의학연구소 2001 구강과학 Vol.13 No.3

A novel glucanhydrolase (DXAMase) from a mutant of Lipomyces starkeyi (KSM 22) has been shown effective in hydrolysis of mutan, reduction of mutan formation by Streptococcus mutans and removal pre-formed sucrose-dependent adherent microbial film and DXAMase has been strongly bound to hydroxyapatitie. These in vitro properties of Lipomyces starkeyi DXAMase are desirable for its application as a dental plaque control agent. This study was performed to determine the adjunctive oral hygiene benefits and safety of dextranase (Lipomyces starkeyi KSM 22 DXAMase)-containing mouthwash when used alongside normal toothbrushing. This 6-month clinical trial was placebo-controlled double-blind design evaluating 1U/㎖ dextranase mouthwash and 0.12% chlorhexidine mouthwash. A total 39 systemically healthy subjects, who had moderate levels of plaque and gingivitis were included. At baseline, 1, 3 and 6 months, subjects were scored for plaque accumulation(Turesky modification of Quigley-Hein's plaque index), gingivitis status (Lo¨e and Silness gingival index), and tooth stain(Area and severity index system by Lang et al). Additionally, oral mucosal examinations were performed and subjects questioned for adverse symptoms. Two weeks after pre-experiment examinations and a professional prophylaxis, the subjects were provided with allocated mousewash and instructed to use 20-ml volumes for 30s twice daily after toothbrushing. All the groups showed significant increase in plaque accumulation since 1 month of experiment. During 6 month's period, the Dextranase mouthwash group showed the least increase in plaque accumulation, compared to the Chlorhexidine mouthwash and placebo groups. As for gingival inflammation, all the groups showed significant increase during 6 months of experiment. The Experimental group (Dextranase mouthwash) also showed the least increase in gingival index score, compared to the Positive control (Chlorhexidine mouthwash) as well as the Negative control (placebo) groups. Whereas the tooth stain was increased significantly in the Positive control group, compared to the baseline score and the Negative control group since 3 months of mouthrinsing. It was significantly increased after 6 months in the Experimental group, still less severe than the Positive control group. As for the oral side effect, the Experimental group showed less tongue accumulation, bad taste, compared to the Positive control group. From these results, mouthrinsing with Lipomyces starkeyi KSM 22 dextranase provided adjunctive benefits to toothbrushing, comparable to 0.12% chlorhexidine mouthwash in inhibition of plaque accumulation and gingival inflammation and local side effects were if anything less frequent and less intense than chlorhexidine, with long-term use of the mouthwash. All data had provided positive evidence for Lipomyces starkeyi KSM 22 dextranase as an antiplaque agent and suggested that further development of dextranase formulations for plaque control are warranted.

우울 증상을 수반한 만성 정신분열병 입원환자에서의 Paroxetine 효과 : 이중맹검 위약대조 연구

한평주,백영석,오상우,전현태,김지영 대한신경정신의학회 2000 신경정신의학 Vol.39 No.4

연구목적: 우울 증상이 있는 만성 정신분열병 환자를 대상으로 항정신병약물과 항우울제인 paroxetine 20mg을 병합 투여하여 우울 증상, 양성 증상, 음성 증상 및 일반적인 정신병리의 호전 여부를 밝히고자 하였다. 방법: DSM-IV 기준상 정신분열병으로 진단된 입원환자 중 우울 증상이 있는 49명을 대상으로 parox-etine과 위약을 이중맹검을 대조한 전향적 임상 연구로서 Hamilton Rating Scale for Depression (HRSD), Brief Psychiatric Rating Scale(BPRS), Positive and Negative Syndrome Scale (PANSS), Extrapyramidal Symptom Rating Scale(ESRS), UKU side effect rating scale(UKU), Clinical Global Impression(CGI)을 기저선과 1주, 2주, 4주, 6주의 시점에서 다섯 번 반복 측정하여 비교 검토하였다. 결과: 36명의 환자가 6주간의 실험을 마쳤다. Paroxetine군과 위약군을 비교해볼 때 HRSD 총점은 양군에서 의미있게 감소되어(p<.01) 우울 증상이 호전되었으나, 두 군간에 통계적으로 의미있는 차이는 없었다. 시간경과에 따라 항우울 효과는 paroxetine 군에서는 2주, 위약군에서는 4주 후부터 관찰되었다. 그리고 paroxetine군과 위약군 모두 PANSS 총점(p<.01)과 CGI 점수(p<.05)가 감소되어 전반적인 정신병리의 감소와 전체적인 임상적 호전을 보였으나, 두 군에서 양성 증상, 음성 증상, 일반적인 정신병리 그리고 약물 부작용은 유의미한 차이가 없었다. Paroxetine군에서 반응군고 비반응군으로 나누어 비교했을 때, 반응군이 비반응군보다 HRSD의 총점(p<.01)과 우울한 기분, 자살, 정신적 불안, 죄채감의 세부 항목에서 유의한 호전을 보였고(p</01),일과 활동, 초기 불면증, 건강염려증의 세부 항목이 호전되어(p<.05) 현저한 우울 증상의 호전을 보였다. 또한 반응군이 비반응군보다 BPRS 총점(p</01)과 PANSS의 일반적인 정신병리 점수(p<.05)가 낮게 나와, 일반 정신병리의 호전을 보였다. 결론: Paroxetine군과 위약군 모두에서 우울 증상의 감소가 있었지만, paroxetine군에서 항우울 효과가 빠르게 나타났다. 두 군간에 양성 증상, 음성 증상, 일반적인 정신병리와 부작용에 대한 차이는 없었다. Paroxetine군에서 반응군은 비반응군보다 우을 증상과 일반적인 정신병리에서 유의한 호전을 보였다. 즉 우울한 기분, 자살, 정신적 불안, 죄책감, 일과 활동, 초기 불면증, 건강염려증이 심한 정신분열병 환자에게 우울 증상을 회복시키는데 paroxetine 20mg의 병용 투여가 효과가 있었다. Objectives: This double-blind placebo-controlled study was conducted to demonstrate the improvement of depressive, positive and negative symptoms, and general psychopatholgy in depressed chronic schizophrenic inpatients with adjunctive paroxetine 20mg therapy in the morning. Methods: Forty nine chronic schizophrenic inpatients with depressive symptoms were randomly received adjunctive paroxetine of placebo for 6 week study period. Therapeutic effect and side dffects were evaluated by means of the Hamiltom Rating Scale for Depression(HRSD),The Brief Psychiatric Rating Scale(BPRS), the Positive and Negative Syndrome Scale(PANSS), the Extrapyramidal Symptom Rating Scale(ESRS), the UKU side effect rating scale(UKU), and the Clinical Global Impression(CGI) at baseline, first, second, forth, and sixth week of treatment in a controlled double-blind design. Results: 18 patients completed six weeks of paroxetine therapy, and 18 patients placebo therapy. 1) Comparison between paroxetine and placebo groups: (1) HRSD total scores in both groups were significantly decreased(p<.01) but there was no statistically significant difference between 2 groups. This study showed that significant effect in paroxetine group appeared at 2nd week of treatment(p<.01), while in placebo group at 4th week of treatment(p<.01). (2) PANSS, BPRS< CGI, ESRS, and UKU : In both groups, PANSS total scores and CGI scores were significantly decreased respectively(p<.01, p<.05) and thus indicated th im-provement of global psychopathology and entire effects. There were no significant differences between 2 groups in positive, negative symptoms, general psychopathology, and drug side effects. 2) Comparison between responding and nonresponding groups in paroxetine adjunctive therapy : (1) Compared with nonresponding group, responding group had significant decrease in HRSD total score(p<.01), in HRSD subitems such as depressed mood, suicide, psychic anxiety, and feelings of guilt(p<.01), and in other subitems such as work and activity, early insomnia, and hypochondriasis(p<.05). (2) Compared with nonresponding group, responding group had significantly decrease in BPRS total score(p<.01) and in general subscale of PANSS(p<.05). Conclusion: The results suggest that both paroxetine and placebo groups were improved in depressive symptoms, but paroxetine group had more rapid improvement than placebo group. There were no significant differences in positive symptoms, negative symptoms, general psychopathology, and drug side effects between two groups. Compared with nonresponding group in paroxetine adjunctive therapy, responding group had significant improvement in depressive symptoms and general psychopathology.

ITU-R BT.470 표준을 만족하는 수정된 디지털 Video encoder의 설계

이민우,김주현,강봉순 東亞大學校附設情報技術硏究所 2005 情報技術硏究所論文誌 Vol.12 No.2

In this paper, we propose a modified design method of multiple standards video encoder which is supporting the National Television Standards Committee (NTSC), Phase-Alternate Line (PAL) and Sequentiel Couleur Avec Memoire (SECAM) broadcasting standards. The proposed encoder can make various broadcasting standard signals, such as NTSC, PAL and SECAM by using the appropriate sub-carrier and bandwidth. Also, in order to separate broadcasting signal into the luminance signal and chrominance signal, the proposed video encoder has Discrete Time Oscillator (DTO) and Low Pass Filter (LPF). So the signal processes with same function can be shared. According to the above state, we expect that the proposed video encoder could increase the hardware efficiency by using the improved method. Moreover, the proposed encoder uses a modified anti-cloche filter and SECAM data flow for applying the SECAM encoding algorithm to digital processing system. So, the proposed encoder can support the NTSC, PAL and SECAM which are using QAM modulation and FM modulation, respectively.

스트라이프 패턴을 사용한 패션 디자인 이미지 분석 및 활용방안

정현 ( Jung¸ Hyun ),우주형 ( Woo¸ Ju Hyung ) 한국기초조형학회 2021 기초조형학연구 Vol.22 No.1

이 연구의 목적은 스트라이프 패턴을 사용한 패션 디자인의 이미지와 디자인 요소와의 관계를 분석하여 스트라이프 패턴 사용에 따른 특정 이미지의 디자인 전개를 위한 실질적인 아이디어를 제공하는 것이다. 연구방법은 2014년 S/S에서 2018년 S/S까지 패션 컬렉션에 등장한 패션 스타일 중 609점을 대상으로 8개 이미지 범주를 사용하여 패션 이미지를 분석하였고, 통계를 사용하여 디자인의 형태적 요소, 스트라이프의 표현요소, 배색 관계에서 패션 이미지와의 관련성을 도출하였다. 스트라이프 패턴 이 사용된 디자인의 이미지는 로맨틱, 모던, 에스닉, 매니시, 엘레강트, 아방가르드, 스포티, 클래식 순 의 빈도를 보였고, 패션 이미지와 디자인 요소의 연관성 분석, 즉 아이템, 도련 위치, 실루엣, 스트라이프 패턴의 선 방향, 선 모양, 반복 형태, 배색 관계 모두에서 패션 이미지에 따른 유의미한 차이가 발견되었다. 그 결과를 토대로 스트라이프 패턴을 사용한 패션 디자인의 이미지 활용방안을 제시하면 다 음과 같다. 로맨틱 이미지는 허벅지 길이의 X 실루엣 원피스 디자인에 고명도의 무채색과 유채색의 조합으로 이루어진 가로/혼합 방향의 선을 사용, 엘레강트 이미지는 풀렝스 원피스에 명도/채도차를 적게 둔 사선/혼합방향의 선, 클래식 이미지는 수트류에 저명도 중심의 전통적 선염 직물용 세로 방향 스트라이프를 사용, 모던 이미지는 간결한 원피스에 간격의 대비, 명도 차가 뚜렷한 무채색의 규칙적 인 세로 방향 스트라이프 사용, 매니시 이미지는 풀렝스 팬츠 아이템에 규칙적 세로 방향 스트라이프 사용, 스포티 이미지는 탑 & 팬츠/원피스 아이템에 채도차를 강조한 가로 방향 스트라이프 사용, 아방 가르드 이미지는 오벌 실루엣과 착시를 일으키는 불규칙적 반복/혼합 방향의 스트라이프 사용, 에스닉 이미지는 풀렝스 원피스에 가로 방향의 다양한 선들과 탁색조 중심의 멀티배색 등 시각적 복잡성을 강조하는 방향으로 활용하면 패션 이미지의 전달이 더욱 강화될 것으로 제안한다. The purpose of this research is to analyze the relationship between the image of fashion design using stripe patterns and design elements, and to provide practical ideas for the development of a specific image using stripe patterns. The research method was to analyze fashion images using 8 image categories targeting 609 fashion styles that appeared in the fashion collection from 2014 S/S to 2018 S/S. And the relationship between fashion image and formative elements of design, expressional elements of stripes, and color combinations was derived by statistical analysis. The fashion design image using stripe patterns among 609 fashion styles was used in the order of romantic, modern, ethnic, mannish, elegant, avant-garde, sporty, and classic. Significant differences were found according to the analysis of the relevance between fashion image and design elements, such as item, hem-line position, silhouette, line direction, line shape, line repetition, and color scheme. Based on the results, suggestions for utilization of the fashion image using stripe patterns are as follows. It can be enhanced that romantic image by X silhouette one-piece dress above knee-length using horizontal/mixed directional lines consisting of white and tinted color combination; elegant image by full-length dress using diagonal/mixed lines with similar value/saturation in colors; classic image by skirt/pants suits using traditional vertical stripes for yarn-dyed fabrics with low values in colors; modern image by simple one-piece dress using regular vertical stripes with clear intervals between lines and value contrast in achromatic colors; mannish image by full-length pants using regular vertical stripes; sporty image by pants/one-piece items using horizontal stripes with saturation contrast in colors; avant-garde image by oval silhouette items using irregularly repeated multi-directional stripes which cause optical illusion; and ethnic image by full-length one-piece dress using various horizontal lines such as zigzag with tone-downed multi-colors which cause visual complexity.