에센셜 오일의 항스트레스 효과

김연주(Yeon-Zu Kim),김윤(Yun Kim) 한국인체미용예술학회 2018 한국인체미용예술학회지 Vol.19 No.2

The aim of this study is to determine the anti-stress effects of essential oils. For this, three different essential oils (lavender, bergamot, sweet orange) were blended and applied to college women for 2 weeks, and pre- & post-psychological stress states, pre- & post-stress indexes and stress resistance were measured. In terms of research design, a single experimental group survey that compared stress changes before and after the test was performed. The study results found the following: 1) Psychological stress states before and after the application of anti-stress essential oils: The changes in psychological stress after the application of three different anti-stress essential oils (lavender, bergamot, sweet orange) were examined. After the oils were applied, average stress levels in college decreased from 2.25 to 1.97 (t=2.269*). Disorder caused by stress also dropped from 2.47 to 1.95 (t=2.888**), showing a statistically significant difference before and after the experiment. Stress-coping capacity increased from 2.96 to 3.12, but no statistical significance was found. 2) Changes in stress indexes and stress resistance before and after anti-stress essential oils: The stress indexes and stress resistance before and after the application of anti-stress essential oils (lavender, bergamot, sweet orange) were measured through an HRV test. The average stress index in the experimental group decreased from 110.05 to 102.50 while stress resistance increased from 84.25 to 93.60. In all categories, statistical significance was observed. 3) Anti-stress effects of essential oils (lavender, bergamot, sweet orange): The said results show that lavender, bergamot and sweet orange essential oils are statistically significant in terms of psychological stress, stress indexes and stress resistance, proving that essential oils have anti-stress effects.

Anti-stress Activity of Sargassum polycystum Extracts Using a Cold Restraint Stress Model

Radipta Lailatussifa,Amir Husni,Agung Endro Nugroho 한국식품과학회 2016 Food Science and Biotechnology Vol.25 No.2

Anti-stress effects of polyphenol extracts of Sargassum polycystum were evaluated. Polyphenol extracts of S. polycystum and diazepam were compared for anti-stress activities using a cold restraint animal stress model. S. polycystum extracts were administered orally at dosages of 150 and 450 mg/kg. Diazepam, an anti-stress agent, was used as a standard drug at 0.18 mg/kg p.o. Both dosages of S. polycystum extracts showed good anti-stress effects. Due to cold restraint stress there was an imbalance in levels of biochemical parameters, including glucose, triglycerides, cholesterol, alkaline phosphatase (ALP), alanine aminotransferase (ALT), and aspartate amino transferase (AST), which were near normalized following adminstration of S. polycystum extracts. Polyphenol extracts of S. polycystum at oral dosages of 150 and 450 mg/kg exerted anti-stress effects.

사회.심리적 스트레스에 미치는 국화 추출 음료의 영향

최진호,김대익,박수현,김동우,조원기,유병팔 한국생명과학회 1999 생명과학회지 Vol.9 No.5

The effects of anti-stress chrysanthemum flower (ASCF) extract drink (ASCF-0.1% and ASCF-0.5% concentrations) were tested for the anti-stress action. ICR male mice (20$\pm$2 g) were fed with basic experimental diets and given free access to water containing these ingredients for 18 days. Psychological stress/sociopsychologcal stress exposed by foot-shock for 1 hour for 3 days. Both ASCF-0.1 and ASCF-0.5 groups in the sociopsychological stress resulted in a significant decrease of 28.1% and 27.3% in plasma corticosterone (CS) secretion compared with psychological stress (control group). Noradrenaline (NA) secretions in the brain were significantly increased 49.7% and 53.9%, respectively, in ASCF-0.1 and ASCF-0.5 groups compared with control group. MHPG-SO4 (3-Methoxy-4-hydroxyphenylethy-leneglycol sulfate) levels in the brain resulted in a marked decreases of 12.9% and 16.6%, respectively in ASCF-0.1 and ASCF-0.5 groups. NA/MHPG-SO4 ratios in the brain of ASCF-0.1 and ASCF-0.5 groups resulted in a significantly increase of 71.3% and 81.0%, respectively, compared with control group. These results suggest that anti-stress chrysanthemum flower (ASCF) drink can effectively ridded the sociopsychological stress.

사회.심리적 스트레스에 미치는 장미 추출 음료의 영향

최진호,김대익,박수현,김동우,조원기,유병팔 한국생명과학회 1999 생명과학회지 Vol.9 No.5

The effects of anti-stress rose fruit (ASRF) extract drink (ASRF-0.1% and ASRF-0.5% concentrations) were tested for the anti-stress action. ICR male mice (20$\pm$2 g) were fed with basic experimental diets and given free access to water containing these ingredients for 18 days. Psychological stress/sociopsychological stress exposed by foot-shock for 1 hour for 3 days. Both ASRF-0.1 and ASRF-0.5 groups in the sociopsychological stress resulted in a significant decrease of 24.3% and 38.0% in plasma corticosterone (CS) secretion compared with psychological stress (control group). Noradrenaline (NA) secretion in the brain were significantly increased 35.9% in ASRF-0.5 group, but NA secretion in ASRF-0.1 group could not be obtained significant result compared with control group. MHPG-SO4 (3-Methoxy-4-hydroxy-phenylethy leneglycol sulfate) levels in the brain resulted in a marked decreases of 16.5% and 18.9% respectively in ASRF-0.1 and ASRF-0.5 groups. NA/MHPG-SO4 ratios in the brain of ASRF-0.1 and ASRF-0.5 groups resulted in a significantly increase of 16.5% and 67.0%, respectively, compared with control group. These results suggest that anti-stress rose fruit (ASRF) drink also can effectively ridded the sociopsychological stress.

구속스트레스를 가한 흰쥐에서 Cholate류의 항스트레스작용에 관한 연구

박인,김양일,이선미,조태순 성균관대학교 약학연구소 1996 成均藥硏論文集 Vol.8 No.1

This study was done to investigate whether cholic acid derivatives have anti-stress activity and what is a cause of this anti-stress effect. Seven cholic acid derivatives (cholic acid, taurocholic acid, ursodeoxycholic acid, tauroursodeoxychoic acid, chenodeoxy cholic acid, dehydrocholic acid, hyodeoxycholic acid) were used, silymarin and valproic acid were used as positive controls. Stress was induced by restraint immobilization technique plus water immersion (24hrs) and adrenal weight, spleen weight, adrenal ascorbic acid, serum cholesterol, lactate dehydrogenase (LDH), alkaline phosphatase (ALP), adrenal cholesterol, glucose and corticosterone levels were measured as stress indicators. Most cholic acid derivatives markedly decreased the adrenal weight, and TUDCA and DHCA increased the spleen weight. The restraint stress induced increments in serum LDH, ALP and cholesterol were attenuated by most cholic acid derivatives. Cholic acid, taurocholic acid and tauroursodeoxycholic acid only increased the content of adrenal ascorbate. While valproic acid showed an inhibitory effect against stress, silymarin did not. Our findings suggest that most cholic acid derivatives have anti-stress effect and that their anti-stress effect is, in part, related to choleretic activity.

치자의 스트레스 관련 생리 활성 : 홍삼과의 비교연구

고홍숙(Hong Sook Ko),이금선(Geum Seon Lee),블랜딜(Blendyl Saguan Tan Lee),박형근(Hyun Geun Park),유구용(Gu Young Yoo),임동술(Dong Sool Yim),정인경(In Kyung Jung),오세관(Sei Kwan Oh),정재훈(Jae Hoon Cheong) 대한약학회 2005 약학회지 Vol.49 No.4

Gardenia Jasminoides (GJ) is traditionally used for treatment of hepatic disease, insomnia, anxiety? and inflammatory disease. The aim of this study is to examine effects of GJ extract in response to stress. Animals of the normal group were not exposed to any stress and the control group were exposed to stress. The rats of the Ginseng and GJ supplementary group were orally administered once a day with 100 mg of red ginseng extract, 100 mg of GJ extract/kg body weight. The mice were given water containing 200 mg of red ginseng extract, 200 mg of GJ extract/100 ㎖ potable water. Animals were given supplements for 7 days without stress, and then were given supplements for 5 days with restraint and electroshock stress. After loading final stress, we examined stress related behavioral changes of experimental animals and measured the levels of blood corticosterone. GJ-supplementation partially blocked the stress effect on locomotion and elevated plus maze test in rats, and also partially blocked stress-induced behavioral changes such as freezing, burrowing, face-washing, smelling and rearing behavior in rats. The effect was almost equipotent to Ginseng's effect. GJ-supplementation didn't influence on fatigue related behavior or physical stress resistance. GJ-supplementation decreased the levels of blood corticosterone which is increased by stress in rats. These results suggest that GJ protects partially the living organism from stress attack and it has the potential to be used as a functional material to alleviate stress response.

사회.심리적 스트레스에 미치는 마인드 토닉(Mind Tonic) 음료의 영향

최진호,김대익,박수현,김동우,조원기,유병팔 한국생명과학회 1999 생명과학회지 Vol.9 No.5

The effects of anti-stress mind tonic (ASMT) drink (ASMT-0.1% and ASMT-0.5% concentration) were tested for the anti-stress action. ICR male mice (20$\pm$2 g) were fed with basic experimental diets free access to water containing these ingredients for 18 days. Psychological stress/sociopsychological stress were exposed by foot-shock for 1 hour for 3 days. Both ASMT-0.1 and ASMT-0.5 groups in the sociopsychological stress resulted in a significant decrease of 19.1% and 41.9% in plasma corticosterone (CS) secretion compared with psychological stress (control group). Noradrenaline (NA) secretions in the brain were significantly increased 23.4% and 35.9%, respectively, in ASMT-0.1 and ASMT-0.5 groups compared with control group. MHPG-SO4 (3-Methoxy-4-hydroxyphenylethyleneglycol sulfate) levels in the brain resulted in a marked decreases of 27.1% and 19.6%, respectively in ASMT-0.1 and ASMT-0.5 groups. NA/MHPG-SO4 ratios in the brain of ASMT-0.1 and ASMT-0.5 groups resulted in a significantly increase of about 70% compared with control group. These suggest that mind tonic anti-stress drink can effectively ridded the sociopsychological stress.

담즙산류의 항스트레스 효능에 관한 연구

조태순,이종찬,조서익,이선미 성균관대학교 약학연구소 1998 成均藥硏論文集 Vol.10 No.1

This study was done to investigate whether cholic acid derivatives have anti-stress activity in various stress models. Two cholic acid derivatives, ursodeoxycholic acid (UDCA) and tauroursodeoxycholic acid (TUDCA), were used. Physical, psychological, chemical and environmental stress models were performed. Adrenal weight, serum glucose levels and ALP activity were elevated in restraint stress model, but this elevation was prevented by UDCA treatment. Moreover, UDCA and TUDCA inhibited exploratory and spontaneous movements in oscillation stress model. In alcohol-induced stress model, TUDCA improved rotarod performance. UDCA and TUDCA significantly reduced the involution of lymphoid organs and the increment of WBC counts in cold stress model. These findings suggest that cholic acid derivatives have antistress effects in various stress models.

학대예방경찰관의 보직이동의도에 영향을 미치는 스트레스원에 대한 연구

김윤희 ( Kim Yun Hee ),조영일 ( Cho Young Il ) 한국경찰학회 2023 한국경찰학회보 Vol.25 No.1

본 연구는 학대예방경찰관의 보직이동의도에 영향을 미치는 직무스트레스원을 확인하고, 직무스트레스를 유발하는 직무를 파악하기 위한 목적으로 설계되었다. 학대예방경찰관 107명을 대상으로 설문 실시하여 수집한 자료를 이용해 분석 실시하였으며, 일반 행정업무 빈도와 보직이동의도 간 관계에서 직무부담 스트레스의 매개효과를 검증하기 위해 SPSS Macro Process v4.0을 활용하였다. 연구결과, 일반 행정 업무 빈도와 보직이동의도 수준 간의 관계에서 직무부담 스트레스가 완전매개효과를 가지는 것으로 확인되었다. 또한 기관협업 업무는 보상부적절 스트레스에 대해 유의한 부적(-) 영향력을 가졌다. 학대예방경찰관이 일반 행정업무를 과도하게 부담할 경우 직무부담 스트레스 수준이 상승하여 보직이동의도가 강해지므로 인력보충, 일반행정직 공무원 배치 등을 통해 직무 부담을 경감한다면 학대예방경찰관의 보직이동이 감소한다고 예상 가능하다. 이와 함께 ‘아동학대사례전문위원회’, ‘통합솔루션회의’와 같은 유관기관 협력기구를 적극 운영하고, 해당 기구에 학대예방경찰관이 참여할 수 있는 기회를 확대한다면 학대예방경찰관의 직무스트레스를 감소시켜 아동학대 대응의 전문성까지 확보할 수 있을 것이라 기대한다. This study was designed to identify job stressor that affect the Intent to change position of Anti-abuse police officers and to identify jobs that cause job stress. The analysis was conducted using data collected by 107 Anti-abuse police officers, and SPSS Macro Process v4.0 was used to verify the mediational effect of job demand stress in the relationship between the frequency of general administrative work and the Intent to change position. As a result of the study, it was confirmed that job demand stress had a full mediational effect in the relationship between the frequency of general administrative work and the level of the Intent to change position. In addition, institutional cooperation work had a significant negative (-) influence on inappropriate compensation stress. If Anti-abuse police officers overburden general administrative tasks, the level of job demand stress increases, and that increases the Intent to change position, so if the job demand is reduced by replenishing manpower and deploying general administrative officials, it is expected that the level of position changing of Anti-abuse police officers, will decrease. In addition, it is expected that if cooperative organizations such as the ‘Child Abuse Case Committee’ and ‘the Integrated Solution Meeting’ are actively operated and opportunities for abuse prevention police officers to participate in the organization will reduce the job stress of Anti-abuse police officers and secure expertise in responding to child abuse.

소양인 형방도적산과 양격산화탕의 항 스트레스효과에 관한 실험적 연구

이승엽,최애련,하진호,이정환,김판준,구덕모,Lee, Seung-Yeop,Choi, Ae-Ryun,Ha, Jin-Ho,Lee, Jung-Hwan,Kim, Pan-Joon,Goo, Deok-Mo 사상체질의학회 2008 사상체질의학회지 Vol.20 No.3

1. Objective This study was done to identify the anti-stress effect of Hyeongbangdojeok-san (HDS), Yanggyeoksanhwa-tang(YST) in Soyangin. 2. Methods Experimental animals were composed of YST, HDS+stress groups which were administered each by 200mg/kg, 400mg/kg and the Saline+stress group. On the 1st day, making the rats forced swim and on the 2nd day, applying Forced swimming test to the rats. After FST, the levels of Corticosterone in the blood were measured. For the study of learning retardation, memory ability and anxiety reaction, experimental animals were composed of YST, HDS+restraint stress groups which were administered each by 400mg/kg, no stress group and the Saline+restraint stress group. Restraint stress were applied 2 hours a day for 3 weeks. On the last day of the 3rd week, Elevated Plus Maze(EPM) was applied to the groups and Morris Water Maze(MWM) was applied to the groups for 7 days. 3. Results 1. As the results of measuring FST which reflects depression, the YST+stress group and the HDS+stress group showed significant effect in comparison with the Saline+stress group. The levels of Corticosterone in the blood were decreased only in the 400mg/kg YST+stress group. 2. As the results of measuring how long EPM which reflects anxiety reaction stayed in the open arm, there was the trend which can suppress anxiety reaction in the HDS+restraint stress group bur no statistical significance. But there was any suppression of anxiety reaction in the YST+restraint stress group. 3. According to the result of MWM, the saline+restraint stress group showed the learning retardation which means increased time arriving at goal compared to the normal group at the second and third day of measurement. On the contrary, a learning retardation was significantly decreased in the YST+restraint stress group at the third day of measurement. 4. Among the Probe trial test a memory loss occurred in the saline+restraint stress group, but memory ability was significantly increased in the YST+restraint stress group. 4. Conclusion: As the results above, Soyangin Yanggyeoksanhwa-tang has significant influence to the antidepression effect, the learning retardation, the anxiety reaction and also in the Hormone level. Hyeongbangdojeok-san has significant influence to the antidepression effect, in the Hormone level, bur not to the learning retardation and anxiety reaction. prefer to drink cold water, and who are suffering from chronic gastritis.