Dislocation Density-Based Constitutive Model and Processing Map for T2 Copper During Isothermal and Time-Variant Deformation

Gang Chen,Yu Jin,Jing Wang,Cheng Zhang,Qiang Chen,Hongming Zhang,Xingjian Zhao,Zhiyong Li,Changhai Xie,Zhiming Du 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.9

Isothermal compression tests were carried out to study the hot deformation behavior of T2 copper under various conditions. The deformation parameters, such as temperature and strain rate, have strong influence on flow stress and microstructureevolution of the alloy. A unified dislocation density-based model considering dynamic recovery and recrystallization wasestablished. And material parameters of the developed model were optimized by genetic algorithm. Comparisons betweenthe experimental and model data demonstrates that the developed model can precisely describe the flow behavior at quitewide range of deformation conditions. Meanwhile, the designed iterative procedure allows the model to be applied in timevariantdeformation conditions. Processing map and microstructure examination were constructed to optimize the processingwindow of the studied alloy. According to the processing maps, flow instability mainly appeared at low temperatures of500–650 °C and strain rates higher than 0.1 s−1. The optimum deformation parameters of T2 copper was concluded as thetemperature range of 700–800 °C and the strain rate of 0.1–1 s−1.

Identification of adhesion-associated extracellular matrix component thrombospondin 3 as a prognostic signature for clear cell renal cell carcinoma

Xiangling Chen,Jiatian Lin,Min Chen,Qiaoling Chen,Zhiming Cai,Aifa Tang 대한비뇨의학회 2022 Investigative and Clinical Urology Vol.63 No.1

Purpose: Clear cell renal cell carcinoma (ccRCC) is a highly aggressive disease, and approximately 30% of patients are diagnosed at the metastatic stage. Even with targeted therapies, the prognosis of advanced ccRCC is poor. The aim of this study was to investigate clinical prognosis signatures by analyzing the ccRCC datasets in The Cancer Genome Atlas (TCGA) and the Clinical Proteomic Tumor Analysis Consortium (CPTAC) and the function of thrombospondin 3 (THBS3) in ccRCC. Materials and Methods: We analyzed the ccRCC datasets in TCGA and CPTAC to search for extracellular matrix (ECM)-related and adhesion-associated genes, and conducted overall survival, Cox, and receiver operating characteristic analyses. We also performed CCK8, colony formation, and transwell assays to compared the proliferation and migration ability of THBS3 knockout cells with those of cells without THBS3 knockout. Results: Comprehensive bioinformatics analysis revealed that THBS3 is a novel candidate oncogene that is overexpressed in ccRCC tumor tissue and that its elevated expression indicates poor prognosis. Our study also showed that knockdown of THBS3 inhibits proliferation, colony formation, and migration of ccRCC cells. Conclusions: In summary, our data have revealed that THBS3 is upregulated in cancer tissues and could be used as a novel prognostic marker for ccRCC. Our findings thus offer theoretical support with bioinformatics analyses to the study of ECM and adhesion proteins in ccRCC, which may provide a new perspective for the clinical management of ccRCC.

Corrigendum: Correction Of The Figure. Identification of adhesion-associated extracellular matrix component thrombospondin 3 as a prognostic signature for clear cell renal cell carcinoma

Xiangling Chen,Jiatian Lin,Min Chen,Qiaoling Chen,Zhiming Cai,Aifa Tang 대한비뇨의학회 2023 Investigative and Clinical Urology Vol.64 No.5

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Identification and Characterization of EDT1 Conferring Drought Tolerance in Rice

Tao Wu,Mingxing Zhang,Hongjia Zhang,Kai Huang,Mojun Chen,Chen Chen,Xue Yang,Zhao Li,Haoyuan Chen,Zhiming Ma,Xunming Zhang,Wenzhu Jiang,Xinglin Du 한국식물학회 2019 Journal of Plant Biology Vol.62 No.1

Basic Leucine Zipper (bZIP) transcription factors(TFs) play important roles in many processes, especially inabiotic stress response in plants. In this study, we characterizeda new gene EHANCED DROUGHT TOLERANCE 1 (EDT1),member of group E of bZIP transcription factor family inrice. The EDT1 protein contains one bZIP domain, oneputative nuclear localization signal (NLS) and six conservedphosphorylation sites. The expression of EDT1 is suppressedby several abiotic stresses, such as cold, droutht, and salt. Corresponding with expression patterns, several stress-associatedcis-acting elements were found in the EDT1 promoter. Theresults of subcellular localization and transactivation abilityanalyses indicated that EDT1 was localized in the nucleusand functioned as a nuclear protein, with its transactivationactivity primarily located in N-terminal. Transgenic riceoverexpressing EDT1 showed drought tolerance that hasbeen significantly improved. Real-time PCR analysis revealedthat some stress-related genes, such as OsbZIP12, SNAC1,OsLEA3, OsbZIP16, OsbZIP10 and OsABI2 were up-regulatedin EDT1 overexpression lines. These results indicate thatEDT1 plays a positive role in drought tolerance and providesvaluable targets for breeding drought-tolerant rice cultivars.

Flow Velocity Deviation of Spinning Solution Under Multi-field Coupling

Zhiming Zhang,Da Hong,Xinyu Huang,Kang Liu,Qiao Xu,Zhen Chen,Qiaoling Ji,Changjin Ke 한국섬유공학회 2023 Fibers and polymers Vol.24 No.10

Rotating jet spinning uses the centrifugal force generated by the high-speed rotation of the motor to keep the spinning solution ejected from the nozzle to form nanofibers. At present, the research work on rotating jet spinning mainly involves the materials, properties and applications of fibers, parameter influence and jet trajectory, while there are few studies on the optimization of spinning core components. In this paper, by analyzing the force and flow state of spinning solution in the flow channel of spinning nozzle, it is found that the maximum velocity region of spinning solution will be offset. The reason for this phenomenon is that the spinning solution is subjected to Coriolis force in the rotating system, resulting in the secondary flow of solution. The relationship between nozzle parameters, solution parameters as well as process parameters, and the outlet velocity of solution was sought, and the structure of spinning nozzle was optimized. The factors affecting velocity offset in straight-tube nozzles and bent-tube nozzles are simulated. High-speed centrifugal spinning experiments were conducted using both unoptimized and optimized nozzles.

ZnO nanowire array ultraviolet photodetectors with self-powered properties

Zhiming Bai,Xiaoqin Yan,Xiang Chen,Hanshuo Liu,Yanwei Shen,Yue Zhang 한국물리학회 2013 Current Applied Physics Vol.13 No.1

A ZnO nanowire (NW) array ultraviolet photodetector (PD) with Pt Schottky contacts has been fabricated on a glass substrate. Under UV light illumination, this PD showed a high photo-to-dark current ratio of 892 at 30 V bias. Interestingly, it was also found that this PD had a high sensitivity of 475 without external bias. This phenomenon could be explained by the asymmetric Schottky barrier height (SBH) at the two ends causing different separation efficiency of photogenerated electronehole pairs, which resulted in the formation of photocurrent. It is anticipated to have potential applications in self-powered UV detection field.

Modeling of SACK-based Fast Retransmission and Recovery

Zhiming Wang,Xiaoping Zeng,Xiaofan Jia,Xue Liu,Li Chen 보안공학연구지원센터 2016 International Journal of Future Generation Communi Vol.9 No.6

Selective acknowledgment (SACK)-based retransmission and recovery mechanism has been implemented in most of current transmission control protocol (TCP) stacks. A new SACK-based loss recovery algorithm is defined in RFC6675 under standard track. Existing models in literatures on modeling TCP SACK, which usually use SACK-based retransmission and recovery mechanism, is no longer accurate for two reasons: 1) they ignore transmission of new packets before retransmission of the last loss; 2) they are based on the strategy that pipe is decreased by 2 upon receipt of a partial ACK, where pipe is the estimated number of outstanding packets. This paper develops a new method to derive the expected number of new packets transmitted between retransmission of the first loss and the last, proposes a model that estimates the expected number of packets transmitted during fast retransmission and recovery phase (FRR) and the corresponding expected duration based on RFC6675. The numerical results show that the proposed model can accurately estimate the expected number of packets transmitted during FRR and the corresponding expected duration based on RFC6675.

Root hair‐specific expansins modulate root hair elongation in rice

ZhiMing, Yu,Bo, Kang,XiaoWei, He,ShaoLei, Lv,YouHuang, Bai,WoNa, Ding,Ming, Chen,Hyung‐,Taeg, Cho,Ping, Wu Blackwell Publishing Ltd 2011 The Plant journal Vol.66 No.5

<P><B>Summary</B></P><P>Root hair growth requires intensive cell‐wall modification. This study demonstrates that root hair‐specific expansin As, a sub‐clade of the cell wall‐loosening expansin proteins, are required for root hair elongation in rice (<I>Oryza sativa</I> L.). We identified a gene encoding <I>EXPA17</I> (<I>OsEXPA17</I>) from a rice mutant with short root hairs. Promoter::reporter transgenic lines exhibited exclusive <I>OsEXPA17</I> expression in root hair cells. The OsEXPA17 mutant protein (OsexpA17) contained a point mutation, causing a change in the amino acid sequence (Gly104→Arg). This amino acid alteration is predicted to disrupt a highly conserved disulfide bond in the mutant. Suppression of <I>OsEXPA17</I> by RNA interference further confirmed requirement for the gene in root hair elongation. Complementation of the <I>OsEXPA17</I> mutant with other root hair EXPAs (OsEXPA30 and Arabidopsis EXPA7) can restore root hair elongation, indicating functional conservation of these root hair EXPAs in monocots and dicots. These results demonstrate that members of the root hair EXPA sub‐clade play a crucial role in root hair cell elongation in Graminaceae.</P>

Maximum magnetic entropy change modulated toward room temperature in perovskite manganites La0.7−xNdx(Ca,Sr)0.3MnO3

Zhiming Wang,Qingyu Xu,Kaixin Chen 한국물리학회 2012 Current Applied Physics Vol.12 No.4

With Nd3þ doping and Ca2+, Sr2+ modulating in the solegel technique, a series of polycrystalline perovskite samples La0.7-xNdx(Ca,Sr)0.3MnO3 (x = 0, 0.05, 0.1, 0.15, 0.20, 0.25) was prepared, their maximum magnetic entropy changes were tuned to room temperature (ΔSH=-1.47 J/kg K at 298 K for La0.45Nd0.25(Ca,Sr)0.3MnO3), an enhancement of the maximum magnetic entropy change (ΔSH=-1.89 J/kg K at 315 K) and its refrigerant capacity (about 45.3 J/kg) had also been obtained under 9 kOe magnetic field variation for La0.55Nd0.15(Ca,Sr)0.3MnO3 contrast to La0.7(Ca,Sr)0.3MnO3.

The Deviation Characteristics of High-speed Train Running Time in Section and its Effect on Transport Capacity

Zhiming Yuan,Qi Zhang,Tao Wang,Feng Chen 보안공학연구지원센터 2016 International Journal of Hybrid Information Techno Vol.9 No.10

Starting from the phenomenon that a large number of trains’ actual arrival & departure time deviate from specified time in train working diagram in the database of high speed railway dispatching system, the paper analyzes the defects of current train running time calculation method. Based on data mining theory, a section running time deviation calculation model for high speed railway train is proposed. Then the properties of train section running time deviation are studied in three different cases (non-stop both at the start and the end of section, stop at the end of section, and departure at the start of section) with the data from a Chinese railway bureau dispatching system, and its further influence on carrying capacity is analyzed. The results show that three deviation cases all fit Gauss distribution and the accumulative deviation time can increase the transport capacity for more than 1 million passengers per year.