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Jaeeun Yoo,Beom Se Son,Eunhee Han,Gyong Gi Yu,이승옥 대한임상검사정도관리협회 2020 Journal of Laboratory Medicine And Quality Assuran Vol.42 No.3
Background: The quantification of the hepatitis B virus (HBV) or hepatitis C virus (HCV) is critical for the diagnosis and prognostic follow-up of the viral infection. The Alinity m assay is a recently developed, fully automated “random-access” system for quantitative molecular assays. The aim of this study was to verify the validity of the Alinity m assay by comparing its performance in HBV and HCV quantifications with the established Abbott m2000 HBV and HCV assays. Methods: The precision, linearity, limit of detection (LOD), correlation with the Abbott m2000 assay, and interference were evaluated. Results: The within-laboratory standard deviation ranged from 0.106 to 0.137 log IU/mL for HBV and from 0.073 to 0.097 log IU/mL for HCV, which was lower than the manufacturer’s specification of 0.25 log IU/mL, indicating good precision. Linearity was observed from 1.14 to 8.14 log IU/mL for the HBV assay and from 1.09 to 7.09 log IU/mL for the HCV assay. The LODs of HBV and HCV were 10 and 6.39 IU/mL, respectively, which were equivalent to or better than those claimed by the manufacturer. For comparative evaluation between Alinity m and m2000 assays, 142 HBV and 70 HCV samples were tested. The correlation test revealed a strong correlation for both markers, and the Passing–Bablok regression analysis did not reveal any significant deviation. Conclusions: The Alinity m assay demonstrated excellent performance for HBV and HCV quantifications with reduced hands-on time and a randomaccess format.
Lost in the Passage: (Japanese American) Women in Julie Otsuka`s The Buddha in the Attic
( Jaeeun Yoo ) 한국영미문학페미니즘학회 2013 영미문학페미니즘 Vol.21 No.3
Julie Otsuka`s latest novel, The Buddha in the Attic, is an unconventional Asian American novel in the sense that it emphasizes the break between Japanese American mothers and their daughters. Despite an attachment to their mothers, Japanese picture brides in the novel are separated from them by paternal authority and physical distance. They become mothers in America, but instead of being a source of inspiration and strength, the alienation they experience from their daughters renders them helpless. Unlike other Asian American novels that thematize mother-daughter relationship, The Buddha in the Attic removes the women from the narrative before they can have any chance to connect with their daughters. Once the collective protagonists of the novel, the Japanese picture brides, leave their neighborhoods to be interned in War Relocation Camps, the reader never gets another glimpse of them. This is a significant structural difference that distinguishes the novel from other writing on Word War II internment, as most writing, including Otsuka`s previous novel, focus on what happens to the Japanese Americans during and after the internment. This paper argues that this radical strategic difference should be read in the context of the post-9/11 era in which the novel was published. By featuring the women`s disappearance after the Pearl Harbor attack as both figurative and literal, Otsuka warns her readers against the loss of minority people and their voices during the similar national hysteria that swept America after 9/11.
Nationalism, Multiculturalism, and Translation: Translation in and of Please Look After Mom
( Jaeeun Yoo ) 한국영어영문학회 2020 영어 영문학 Vol.66 No.2
In 2011, Please Look After Mom, a translation of a mega-bestseller novel in Korea, entered the American literary market with a significant commercial success. A close analysis of the translation, along with the celebration and controversy it caused on both sides of the pacific, reveal interesting and often paradoxical ideas about translation and its role in introducing cultural differences. The Korean original, Ommarul Put’akhae, employs translation to signify radical unsettling differences, and as a metaphor that epitomizes a meeting between the self and the other, translation raises questions concerning the complex relationship one has with the other. The translation of Please Look After Mom reduces critical layers of the original novel, and the reason why it was noted and read by many American readers had more to do with the U.S. than with Korea―more specifically, the cultural dilemma that the U.S. found itself in after 9/11. At the same time, however, Please Look After Mom retains and even possibly strengthens the peculiar way in which translation is thematized in the Korean source text. In other words, as a metaphor that epitomizes a contact between the self and the other, translation in and of Please Look After Mom raises important questions concerning national identities, cultural differences, international politics and interpersonal responsibilities. This article reads Please Look After Mom not only as a translated text, but also as a cultural phenomenon to examine cultural and political forces at work at the site of translation today.
Jaeeun Yoo,Gun Dong Lee,Jee Hae Kim,Seung Nam Lee,Hyojin Chae,Eunhee Han,Yonggoo Kim,김명신 대한진단검사의학회 2020 Annals of Laboratory Medicine Vol.40 No.2
Background: Hereditary breast and ovarian cancer syndrome (HBOC) is caused by pathogenic variants in BRCA and other cancer-related genes. We analyzed variants in BRCA gene and other cancer-related genes in HBOC patients to evaluate the clinical validity of next-generation sequencing (NGS) multi-gene panel testing. Methods: The BRCA1/2 NGS testing was conducted for 262 HBOC patients. Multiplex ligation-dependent probe amplification and direct Sanger sequencing were performed for confirmation. Multi-gene panel testing was conducted for 120 patients who did not possess BRCA1/2 pathogenic variants but met the National Comprehensive Cancer Network criteria. Results: Pathogenic variants in BRCA1/2 were detected in 30 HBOC patients (11.5%). Additionally, four out of the 120 patients possessed pathogenic variants by multi-gene panel testing (3.3%): MSH2 (c.256G>T, p.Glu86*), PMS2 (c.1687C>T, p.Arg563*), CHEK2 (c.546C>A, p.Tyr182*), and PALB2 (c.3351-1G>C). All the four patients had a family history of cancer. Conclusions: Multi-gene panel testing could be a significant screening tool for HBOC patients, especially for those with a family history of cancer.
Low Power and Accurate Current Driver IC for Electrical Impedance Tomography Applications
Jaeeun Jang,Hoi-Jun Yoo 대한전자공학회 2019 Journal of semiconductor technology and science Vol.19 No.1
In this paper, a current driver targeting for Electrical Impedance Tomography is proposed. The proposed IC is designed based on active electrode configuration. First, high output impedance current driver is implemented with phase compensation scheme through a delay-locked loop (DLL) to significantly alleviate a phase shift and a required power consumption in the driver. Second, low-power pseudo-sine wave generator is used not only for a lowharmonic distortion but also for a flexible injection frequency utilization. Third, the calibration unit is proposed to compensate injection-current amplitude variations among active electrodes. As a results, the proposed current driver IC guarantees more than 1 MΩ output impedance over a wide range of injection current up to 400 μA and operating frequency from 1 kHz to 5 MHz, only consuming 2.79 mW.
모바일트레이딩시스템 홈 화면 정보 구조화 디자인에 관한 연구
신재은(Jaeeun Shin),유승헌(Seunghun Yoo) 한국HCI학회 2023 한국HCI학회 학술대회 Vol.2023 No.2
국내 증권거래앱 시장은 빠른 속도로 성장하고 있으며, 증권사들 또한 모바일 트레이딩 시스템 (MTS)을 개편해 사용자의 편의성을 확대시키는데 주력하고 있다. 본 연구에서는 사용자들이 MTS 앱의 홈 화면을 이용할 때 선호하는 정보 구조화 방식에 대해 심층 인터뷰를 통해 중점적으로 분석하고, 해당 결과를 기반으로 홈 화면의 사용성을 높일 수 있는 UX 디자인을 제시하였다. 사용자 테스트 결과 새롭게 제시한 탭 방식의 디자인이 기존 리스트 구조 방식에 비해 전반적인 만족도가 높았으며, 사용자들이 원하는 종목을 더 빠르게 찾는 것을 확인할 수 있었다.
MIND 식단교육을 이용한 치매예방 영양프로그램이 고위험 치매노인의 인지기능 변화에 미치는 영향
송재은 ( Jaeeun Song ),최성혜 ( Seong Hye Choi ),홍창형 ( Chang Hyung Hong ),정지향 ( Jee Hyang Jeong ),문소영 ( So Young Moon ),나해리 ( Hae Ri Na ),박희경 ( Hee Kyung Park ),박유경 ( Yoo Kyoung Park ) 대한영양사협회 2021 대한영양사협회 학술지 Vol.27 No.4
This study examined the effect of the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet of the Korean multi-domain dementia prevention program on the cognitive functions of the elderly with dementia risk factors. We developed the program including nutrition, exercise, cognitive training, vascular disease prevention, and motivation. One- hundred and fifty-three participants aged 60∼79 years with at least 1 dementia risk factor were randomly assigned in a 1:1:1 ratio to the facility-based intervention (FMI), home-based intervention (HMI), and the control group. The nutrition education program consisted of 10 classes over 24 weeks: the FMI received 7 group sessions and three 1:1 sessions, the HMI received 4 group sessions and three 1:1 sessions with 3 homework sessions. The Nutrition Quotient for Elderly (NQ-E) and the Mini Nutritional Assessment (MNA) were used to evaluate nutritional status. The Repeatable Battery for the Assessment Neuropsychological Status (RBANS), Korean Mini-Mental State Examination (K-MMSE), and the Cognitive Complaint Interview (CCI) were used to evaluate cognitive functions. A total of 136 people completed the program with an 11.1% dropout rate. The NQ-E (P=0.009) and RBANS (P=0.001) scores significantly increased in the FMI (N=45) and HMI (N=49) groups compared to the control group (N=42) after the study. The changes in the score of MNA and CCI did not differ significantly between groups. In conclusion, the nutritional intervention which focused on the MIND diet as a part of a multi-domain intervention program had a positive effect on the improvement of healthy eating habits and cognitive function scores in the high-risk dementia group.