韓ㆍ日交流の發展方案についての考察

金明信 경상대학교 일본문화연구소 2001 日本學報 Vol.- No.7

중국 소설의 구조와 서술방식에 대한 연구 -<<영웅전>>을 중심으로

김명신 한국중국문학이론학회 2004 중국문학이론 Vol.4 No.-

특허등록출원$\cdot$명세서작성요령 - 건축부문 -

김명신 한국발명진흥회 1977 特協 Vol.2 No.9

교육운동의 새로운 패러다임 : 탈학교운동의 업그레이드, 홈스쿨 네트워크의 가능성

김명신 문화과학사 2010 문화과학 Vol.- No.61

金錢草 추출물이 고지방 식이에 의한 생쥐의 지질 대사 변화에 미치는 영향

김명신,김경옥,김경수,박수연,양승정,위통순,최창원,Kim, Myung Sin,Kim, Kyeong Ok,Kim, Kyeong Su,Park, Soo Yeon,Yang, Seung Joung,Wei, Tung Shuen,Choi, Chang Won 대한한의학방제학회 2015 大韓韓醫學方劑學會誌 Vol.23 No.1

Objectives : Herba on lipid levels in serum and lipid accumulation in liver tissue in high fat diet-induced hyperlipidemic mice. Methods : Experimental groups were subdivided into four; Normal diet group (Nor), Hyperlipidemic mice (Con), Lysimachiae Herba water extract administered mice (LWE), Lysimachiae Herba methanol extract administered mice (LME). Thereafter the changes in body weight, total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, AST, ALT, fasting blood glucose in serum were measured. In addition histopathological changes in liver tissue was also observed. Results : Body weight, AST and ALT were not affected by the administration of water or methanol extracts of Lysimachiae Herba. However, methanol extracts of Lysimachiae Herba down regulated the total cholesterol and triglyceride in high fat diet - induced hyperlipidemic mice. Conclusions : In this study, results of total cholesterol and triglyceride showed significant effect in LME compared with LWE, but other results didn’t. Therefore, it is necessary to have more study of Lysimachiae Herba to apply hyperlipidemia.

영화 〈畵皮〉에 나타난 원전 서사와 변용

金明信 한국중국소설학회 2014 中國小說論叢 Vol.42 No.-

原文〈畵皮〉是淸代文人蒲松龄創作的文言小說。〈畵皮〉是引起讀者的想像與閱讀興趣的故事。這篇作品雖然是很短的內容,主要男女三個人造成故事,在人和妖․愛情和慾望․現實和虛構方面上非常緊密地描寫出來,讓人們感覺到一部分。在中國古典小說中,〈畵皮〉具有幻想性與敎訓性,我們可以評價它已經到了獨特的地步。〈畵皮〉是以電影和电视剧來多种多样地運用着,其中陈嘉上导演的〈畵皮〉是把原典的內容很好地活用了。電影〈畵皮〉是原典的愛情敍事爲中心,做出王生ㆍ小唯ㆍ佩蓉ㆍ龐勇ㆍ夏冰ㆍ小易等等的角色。原典是三角形構圖的愛情關系,電影是六個人互相复杂地缠绕在一起,一種現代式的愛情故事。 王生是從原典的花花公子變成爲知道眞正的愛情的人物形象,小唯是好像利己的人物,爲了愛情犧牲一切的妖怪。佩蓉是在原典與電影上一樣,至高至純的,爲了丈夫犧牲自己的傳統女人的形象。與原典有一些不同的人物是龐勇ㆍ夏冰和小易。龐勇與夏冰是從原典的道士變成兩個人物。他門就是扶危济困的俠客與退魔師。小易是原典上根本無有的人物,無條件地愛着小唯,亂殺許多人。這些人物是比原典更幻想的,真实性也更强。作家是通過想像創造出來幻想與真实性。幻想與真实性是好像相反的槪念,在電影上露出原典的妙味,調和構成了。電影〈畵皮〉是把幻想與實在性適當調整的,更加培養讀者閱讀興趣,非常有人氣。電影〈畵皮〉是把原典的幻想性更宽面儿的表現了,反映出實在性,也表現出人間界與幻想界會成爲調和。所以電影〈畵皮〉是很好的反映原典的敍事,我們可以評價它也有一定値得的部分

경쟁 치열한 중국 프랜차이즈 업계 한국계 성공사례 등장 -가맹점 관리 어려워 실패율 높아 중국인의 기호, 문화 이해해야 성공

김명신 포스코경영연구원 2014 CHINDIA Plus Vol.91 No.-

Effects of Interleukin-9 Blockade on Chronic Airway Inflammation in Murine Asthma Models

김명신,조경아,조영주,우소연 대한천식알레르기학회 2013 Allergy, Asthma & Immunology Research Vol.5 No.4

Purpose: Asthma is a chronic inflammatory disease of the airways associated with structural changes and airway remodeling. Interleukin (IL)-9 haspleiotropic effects on both inflammatory cells and airway structural cells, which are involved in asthma pathogenesis. We evaluated the effects ofIL-9 blockade on chronic airway inflammation. Methods: Acute airway inflammation was induced in Balb/c mice using aerosolized ovalbumin (OVA),whereas chronic asthma was induced by OVA exposure for 5 weeks with anti-IL-9 or isotype-matched antibody (Ab) treatment during the OVA challenge. Inflammatory cells in bronchoalveolar lavage fluid (BALF) were counted and lung tissues were stained to detect cellular infiltration, mucus deposition,and collagen accumulation. The levels of interferon (IFN)-γ, IL-4, IL-5, IL-9, IL-17, and immunoglobulin E (IgE) in BALF were measured usingenzyme linked immunosorbent assays, and profiles of inflammatory cells and subsets of T helper (Th) cells were analyzed using flow cytometry. Results:IL-9, IL-17, and IFN-γ levels were significantly increased in the chronic group compared to the acute asthma group. However, the number of IL-9-positive cells was not affected, with a decrease in Th17 cells in OVA-challenged caspase-1 knockout mice. Numbers of eosinophils, neutrophils, Bcells, mast cells, and Th17 cells decreased after administration of anti-IL-9 Ab. Total IgE, IL-5, IL-9, and IL-17 levels were also lower in the anti-IL-9group. Conclusions: Our results suggest that anti-IL-9 Ab treatment inhibits pulmonary infiltration of inflammatory cells and cytokine production,especially IL-17. These results provide a basis for the use of an anti-IL-9 Ab to combat IL-17-mediated airway inflammation.

Flow Cytometry-Assisted Basophil Activation Test as a Safe Diagnostic Tool for Aspirin/NSAID Hypersenstivity

김명신,조영주 대한천식알레르기학회 2012 Allergy, Asthma & Immunology Research Vol.4 No.3

Purpose: Aspirin and non-steroidal anti-inflammatory drugs (ASA/NSAIDs) are common causes of drug hypersensitivity. An oral provocation test is the only definitive diagnostic test. This study assessed the reliability of a flow cytometry-assisted basophil activation test (FAST) as a safe diagnostic method for ASA/NSAID-induced hypersensitivity, as its high sensitivity and specificity have been demonstrated for many other drugs. Methods: Eighteen patients and 11 controls were enrolled. Using a Flow-CAST kit® (Bühlmann Laboratories AG, Schönenbuch, Switzerland), 29 analyses with aspirin,ibuprofen, and diclofenac were performed by flow cytometry to detect double-positive staining of anti-IgE and anti-CD63. The stimulation index was defined as the activated basophil percentage after drug stimulation/basally active basophil percentage. A stimulation index≥2 and an absolute activated basophil percentage≥5 were considered positive. Results: Patients with hypersensitivity to ASA/NSAIDs were predominantly female, and the prevalence of atopy was higher in patients than in controls. A sensitivity of 61%, specificity of 91%, positive predictive value of 92%, and negative predictive value of 59% were achieved. Conclusions: FAST is a useful additional method for diagnosis of hypersensitivity reactions to ASA/NSAIDs. Further development is required to increase the sensitivity of the test.

시각화 자료를 활용한 초등학생용 현실치료 셀프카운슬링 훈련프로그램의 개발과 효과검증

김명신,김원중 한국상담학회 2013 상담학연구 Vol.14 No.5

The purpose of this study was to develop a reality therapy self-counseling training program using visual aids for elementary school students and to verify its effectiveness. The program consisted of 4 stages; the first five 60-minute sessions were to help subjects learn the fundamental theory, the second two 60-minute sessions were to familiarize them with visual aids for self-counseling, the third three 50-minute sessions were to teach them applying it to the life scene by help of teachers, and the fourth two 40-minute sessions were without any help. To verify the effects of the program, the stress-coping skill test, the problem-solving skill test and the self-efficacy test were conducted on 320 students in fifth or sixth grade and 30 of them who made low marks on all three tests were selected as subjects of the experiment. They were assigned randomly to an experiment group and a control group by 15s. The results were as follows: First, the program was found to be effective to improve the stress-coping skill. After the program, the stress-coping skill became better in the experiment group. The effect was the same even in 2 months later test. Second, the program was effective to improve the problem-solving skill. The problem-solving skill was remarkably improved in the experiment group. The additional test showed that the experiment group maintained the skill. Third, the program was effective to heighten self-efficacy. The control group did not show significant changes, whereas the experiment group showed a remarkably higher self-efficacy. The effect was the same even in the additional test. 본 연구는 초등학생이 시각화 자료를 통해 자신의 문제를 스스로 해결할 수 있는 현실치료 셀프카운슬링 프로그램을 개발하고 그 효과를 검증하는 것이다. 이를 위해 먼저 선행연구를 통해 현실치료의 원리와 셀프카운슬링의 의미를 파악한 후, 초등학생들에게 가능하도록 시각화 자료를 제작하여 셀프카운슬링 훈련 프로그램을 만들었다. 본 프로그램은 4단계 총 13회기로 구성되었는데, 1단계(1회기-5회기)는 핵심이론 익히기, 2단계(6, 7회기)는 시각화 자료 익히기, 3단계(8-10회기)는 생활에 적용하기, 4단계(11, 12회기)는 확인하기이며, 마무리 활동으로 1회기를 더 진행하였다. 프로그램의 효과를 검증하기 위해 경상남도 S초등학교 5, 6학년 재학생 320명을 대상으로 스트레스 대처능력 검사, 문제해결력 검사, 자기 효능감 검사를 실시하여 3가지 검사에서 모두 낮은 점수를 얻은 학생들 중 부모의 동의를 얻은 30명의 학생들을 선정하여 실험집단과 통제집단에 각각 15명씩 무선 배치하였다. 프로그램 실시 전 사전검사로 스트레스 대처능력검사, 문제 해결력 검사, 자기 효능감 검사를 실시하였고 프로그램을 마친 직후 사후검사를 하였으며 두 달 후에 추후검사를 실시하여 변화추이를 관찰하였다. 연구결과 본 프로그램은 스트레스 대처능력과 문제해결력, 자기 효능감에 유의미한 향상을 보였다. 그러므로 시각화자료를 활용한 현실치료 셀프카운슬링 훈련 프로그램은 문제해결력, 스트레스 대처능력, 자기 효능감에 긍정적인 영향을 미친다고 판단된다.