치근단절제술 후 Cold-burnished Gutta-percha가 치유에 미치는 임상적 연구

홍한표,조용범,홍찬의 단국대학교 치의학연구소 1994 단국대치의학연구소논문집 Vol.6 No.1

Mineral Trioxide Aggregate(MTA)의 치근단 역충전효과에 대한 임상적 연구

홍찬의,홍한표,조용범 단국대학교 치의학연구소 1994 논문집 Vol.6 No.1

Although numerous materials have been recommended as root end filling material, so far no material has been found to satisfy all of the requirements of an ideal material. An experimental material, mineral trioxide aggregate(MTA), has been recently developed to seal off all pathways of communication between the root canal system and the external surface of the tooth. This material has been used to seal the root end cavities in extracted teeth and similar preparations in beagle dogs and shown very promising results. In this clinical study, 5 anterior teeth from three patients were used to clinically and radiographically evaluate the efficacy of MTA as a root end filling material on a short-term basis. After removing the apical 2 to 3 ㎜ of the roots, The root end cavities were prepared and filled with MTA. The results were as follows: 1. All the cases demonstrated excellent healing radiographically and absence of clinical signs and symptoms. 2. According to the results, it appeared that MTA had a good sealing ability and biocompatibility. 3. MTA showed very promising results as a root end filling material, but Long-term clinical retrospective studies of many cases are recommended to get the most valid evaluations.

버팀보로 지지된 흙막이벽의 거동에 관한 연구

홍원표,여규권,윤중만,조용상 중앙대학교 기술과학연구소 1997 기술과학연구소 논문집 Vol.27 No.-

버팀보 축력으로부터 산정된 측방토압은 지표면에서 굴착깊이의 17%에 해당되는 깊이까지 선형적으로 증가하다가 그 깊이 아래로부터는 일정토압분포를 보이는 사다리꼴모양의 분포를 보였다. 이 일정토압 분포부분의 토압 크기는 평균적으로 최종굴착깊이에서의 Rankine 주동토압의 58%에 해당하거나 연직상재압의 17%에 해당하였다. 또한 흙막이벽의 수평변위와 굴착깊이와의 관계로부터 흙막이구조물의 안정성을 판단할 수 있는 시공관리기준을 설정하였다. 흙막이벽의 수평변위량이 굴착깊이의 0.20%보다 작으면 흙막이벽과 굴착배면지반은 안정된 상태에 있다. 그러나 벽체의 수평변위가 굴착깊이의 0.20%보다 크게 발생하면 굴착공사의 안정성을 주의깊게 관찰해야만 하며, 필요하다면 흙막이 구조물을 보강해야만 한다. The lateral earth pressures on braced earth retaining walls, which are estimated form the measured strut force, shows a trapezoidal distribution that the earth pressure increases linearly with depth from the ground surface to 17% of the final excavation depth, and then keeps constant value. The maximum lateral earth pressure was same to 58% of Rankine's active earth pressure or 17% of the vertical overburden pressure at the final excavation depth. Also, empirical criterion is established for construction management to monitor and ensure the stability of deep excavation from the relationship between horizontal displacement of wall and excavated depth. If the horizontal displacement of wall measured from inclinometer shows less than 0.20 percent of the excavated depth, the retention wall and surrounding ground exist under stable state. When the horizontal displacement is developed more than 0.20 percent of the excavated depth, excavation works should be carefully observed and reinforced the earth retention wall, if necessary.

이하선에 발생한 섬유성 조직구종 치험례

홍성표,박용구 大韓成形外科學會 1987 Archives of Plastic Surgery Vol.14 No.3

Nonepithelial tumor or the salivary glands re very rare. The most common types of benign nonepithelial tumor of the salivary gland are angioma, neurofibroma and lipoma which together represent less than 5 per cent in adult. Fibrous histiocytoma is originated form tissue histiocyte and most commonly this tumor occurs in the skin, but it is also found in the parenchymal organ such as cornea, orbit, sinus, bronchus and bladder. To our knowledge, only three patients with fibrous hisiocytoma arising in the parotid gland have been reported by Nilsen(1978), Shapshay(1979) and Fayemi(1980). To theses we add a fourth case of 21-year old man. We have reported a case of fibrous hisiocyoma of parotid gland in a 21-year old man, which was excised by parotid lobectomy and repaired by free nerve graft.

Mineral Trioxide Aggregate(MTA)의 치근단 역충전효과에 대한 임상적 연구

홍찬의,홍한표,조용범 단국대학교 치의학연구소 1994 단국대치의학연구소논문집 Vol.6 No.1

RAPD 표지자 분석에 의한 가시아메바속 한국분리주의 유전적 지위

홍용표,오승환,라미숙,임경일 INSTITUTE OF TROPICAL MEDICINE YONSEI UNIVERSITY 1995 YONSEI REPORTS ON TROPICAL MEDICINE Vol.26 No.1

가시아메바 속(Acanthamoeba spp.)의 DNA 염기 구성 정보와 관계없이 임의의 10개의 염기로 구성된 프라이머를 사용하여 random amplified polymorphic DNA-polymerase chain reaction(RAPD-PCR)에 의해 게놈 상의 DNA를 무작위로 증폭하여 확인된 표지자로써 한국 분리주 및 외국 분리주와 기존의 알려진 4개 가시아메바 종간의 유전적 근연관계 분석을 통해서 4개 한국분리주의 분류상의 성상을 규명하였다. 본 연구에서 A. culbertsoni, A. hatchetti, A. triangularis, A. polyphaga와 한국 분리주인 YM-2, YM-3, YM-4, YM-5, 그리고 외국 분리주인 HOV의 게놈 DNA는 18종류의 프라이머에 의하여 다양한 양상의 증폭산물을 보였으며, 그 중 9개 프라이머는 한국 분리주간에도 특이성을 보이는 RAPD 표지자를 제공하였다. 총 18개의 프라이머에 대한 증폭산물을 대상으로 각 시료의 유사도를 조사한 결과, A. culbertsoni는 A. hatchetti, A. triangularis, A. polyphaga와 유사도가 각각 0.300, 0.308, 0.313이었고, A. hatchetti와 A. triangularis간의 유사도는 0.838이었다. 한국 분리주 YM-2, -3, -4간의 평균 유사도는 0.959이었고, YM-2, -3, -4와 A. hatchetti, A. triangularis간의 평균 유사도는 0.832이었다. 한국 분리주 YM-5는 YM-2, -3, -4 간의 비교에서 평균 0.237의 유사도를 보인 반면, A. culbertsoni와 유사도 0.857을 보여, 다른 한국 분리주보다 A. culbertsoni와 유전적으로 유사함을 알 수 있었다. UPGMA법에 의한 유전적 근연관계 분석 결과 phenogram 상에 두개의 분지군이 존재하는데, A. hatchetti, A. triangularis 및 3개 한국 분리주 (YM-2, -3, -4)가 하나의 분지군을, A. culbertsoni, A. polyphaga, HOV주, 및 YM-5가 다른 분지군을 형성하는 것으로 나타났다. 게놈 DNA 상의 변이에 근거하여 볼 때, YM-5 주는 유전적으로 A. culbertsoni와 거의 유사한 분리주이며 한국 분리주는 최소 2종 이상의 가시아메바로 분류할 수 있다고 사료된다. Genetic status of Acanthamoeba spp. were tested on the basis of random amplified polymorphic DNA(RAPD) marker analysis. Four previously established Acanthamoeba species. 4 Korean isolates of Acanthamoeba sp.. and one American isolate of Acanthamoeba sp. were analyzed by RAPD-PCR using an arbitrary decamer primers. Amplification products were fractionated by agarose gel electrophoresis and stained by ethidium bromide. Eighteen primers producted DNA amplification profiles revealing clear differences among 4 species. Nie of them also produced DNA amplification profiles which included some isolate-specific amplification products. On the basis of amplified fragments by 18 primers, the pairwise similarity indices between A. culbertsoni and other species (i.e., A. hatchetti, A. triangularis, A. polyphaga) were 0.300, 0.308, and 0.313, respectively. Similarity index between A. hatchetti and A. triangularis was 0.833. The mean similarity index among the 3 Korean isolates (YM-2,-3,-4) was 0.959 and 0.832 among them and 2 other species (A. hatchetti and A. triangularis). The mean similarity index among YM-5 and other Korean isolates (YM-2,-3,-4) was 0.237. However, the similarity index between YM-5 and A. culbertsoni was 0.857, which suggests that YM-5 is genetically more similar to A. culbertsoni than other Korean isolates. Phenogram reconstructed by UPGMA method revealed that there are two groups: one group consists of A. hatchetti, A. triangularis, and 3 Korean isolates (YM-2,-3,-4), and the other group consists of A. culbertsoni, A. polyphaga, HOV, and YM-5.

중증 만성정신질환자 수의 추산 : Through Two Community Surveys 두 지역사회 조사를 중심으로

홍진표,김윤,배재남,정유진,강영호,양병국,김용익,김병후,이철,조맹제 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.2

국내 중증 만성정신질환자 수를 추정하기 위하여 일 농촌 및 대도시 지역의 지역의료보험 및 의료보호 대상자 중 1993년 1년간 의료기관에서 정신증 상병(ICD-9 code 상 290-299) 및 알콜 남용/중독, 성격장애 및 정신박약 진단하에 치료를 받은 적이 있는 사람에 대해 설문조사를 실시하였다. 연구자들이 개발한 진단도구를 이용하여 진단을 평가하고, Strauss-Carpenter scale 등을 이용하여 기능 장애를 평가하고 유병기간 등을 조사하였다. 결과를 요약하면 다음과 같다. 1) 진단평가상 정신분열병군(61.1%)이 가장 많았으며, 정동장애군(23.7%), 알콜장애군(11.2%), 기질성 정신장애군(4.0%)의 순서이었다. 2) 직업활동정도는 진단군별로 차이가 많았다. 지난 1년간 직업활동이 6개월 미만이거나 전혀 없는 환자 비율이 정신분열병군은 67.2%, 알콜장애군 52.0%, 정동장애20.8%의 순으로 정신분열병군이 가장 불량하였다. 3) 사회활동도 진단군별로 차이가 많아서 지난 1년간 의도적, 사회활동이 없는 비율이 정신분열병군이 가장 높았고(72.3%), 알콜장애군(32.0%), 정동장애군(20.7%)의 순이었다. 4) 국내 의료보험 및 사회복지시설 이용 자료 등을 토대로 본 조사 결과를 적용한 결과 국내중증 만성 정신질환자의 수는 약 8만 7천명으로 추산되었다. Objectives: The purpose of this study was to estimate the number of serious and persistent mentally ill patients in Korea. Methods : Study populations were recruited from medical insurance data of two district areas ; one rural and the other urban areas. Subject were all mentally ill who had ever visited any hospital in 1993 and were diagnosed as having psychosis, personality disorder and drug abuse. We conducted a home visiting survey applying semi-structured diagnostic interview, assessing the level of social adjustment with Strauss-Carpenter Scale, and past psychiatric history by the trained researchers, in October and November,1994. Results : According to diagnostic assessment schizophrenic patients constituted the major portion(61.1%) of study subjects. The distribution of occupational functions and social contacts was variable according to diagnosis. Most schizophrenic patients were unemployed or worked less than 6 months in the previous year(67.2%), and showed poor social contact(72.3%). But affective disorder patients were relatively independent in job maintenance and social relationship. Alcoholic patients lay between those of schizophrenic and affective disorder groups. It was estimated that about 87,000 adult Koreans were suffering from chronic mental disorders which seriously interfere with their daily life. Conclusions : Serious and persistent mentally ill patients were common in Korea. Community support program should be provided for them.

치근단절제술 후 Cold-burnished Gutta-percha가 치유에 미치는 임상적 연구

홍한표,조용범,홍찬의 단국대학교 치의학연구소 1994 논문집 Vol.6 No.1

The purpose of this retrospective study was to radiographically evaluate the apical sealing efficacy of cold-burnished gutta-percha as a root-end filling material. Radiographs of 41 teeth from 37 patients were used, with the recall period ranging from a minimum of 1 yr to a maximum of 6.7 yr. Radiographic findings were classified into one of three groups: 1. complete healing; 2, incomplete healing(scar tissue); 3, unsatisfactory healing. The results were as follows: 1. There was no significant difference in frequency of operation between male and female. 2. The teeth most frequently operated on were the maxillary central incisors (39%). The Maxillary lateral incisors were the second largest group in frequency at 34%. 3. Patients between 21 and 40 yr of age formed the single largest group. 4. Complete healing was found in 58.5% of the recall cases, while incomplete and unsatisfactory healing occurred in 34.2% and 7.3% of the cases, respectively. Based on this retrospective study, We concluded that 38 of 41 cases(92.7%) were considered to be successful and 3 cases (7.3%) were determined to be failures.

정보통신산업의 국민경제적 위상과 전망

김용규,문석웅,홍동표 한양대학교 디지털경제연구소 2003 디지털경제연구 Vol.8 No.-

배양 표피세포 이식의 생착에 관한 연구

조용근,홍성표,장충현,이두형 大韓成形外科學會 1991 Archives of Plastic Surgery Vol.18 No.1

We cultured the keratinocytes from different donors for 3 weeks and the cultured keratinocyte sheets were applied to the 15 cases of patients who had hypertrophic scars on their extremities. (auto-??allografting) And the applied keratinocyte sheets were studied for the adaptation, growth ?? differentiation with light and electron-microscopy. The results were as follows; 1. Grafted epidermal cells started differentiation from second week post-grafting and showed a similar appearance to the normal epidermis at fourth week post-grafing. 2. Keratohyalind granules were seen from fourth week post-grafting and showed a normal appearance at fifth month post-grafting. 3. Immature desmosome-tonofilament complexes were seen at cultured epidermal sheet and showed a normal appearance at fifth month post-grafting. 4. Rete ridges showed its appearance at fourth week post-grafting and showed a normal appearance at fifth month post-grafting. 5. Fine structures of epidermo-graft bed junction showed a discontinuous appearance at second week post-grafting and showed a normal continuous appearance at fifth month post-grafting. In summary, the 'take' of grafted epidermal sheets begins at fourth week post-grafting and completed at fifth month post-grafting.