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The Relief Effects of Ramelteon on Refractory Chronic Migraine: A Case Report
Yi-Cheng Hou1,Chien-Han Lai 대한정신약물학회 2016 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.14 No.4
The selective melatonin receptor agonism effect of ramelteon is useful for insomnia. Here we wanted to present a refractory chronic migraine case, who had significant improvements in migraine after using ramelteon. The possible mechanism for the ramelteon in the migraine relief might be related to melatonin effects.
Yi-Cheng Hou,Chien-Han Lai 대한정신약물학회 2015 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.13 No.3
The impacts from the bupropion on the brain structures have seldom been mentioned in the literature. The bupropion is a kind of antidepressant with dual action in the norepinephrine and dopamine receptors. Here we have a case to share about the bupropion-related effects in the brain structure.
K-doping effect of the superconductivity in K2xFeTe1-xSx (0.07 ≤ x ≤ 0.3)
Cheng Cheng,Zhenjie Feng,Qing Li,Tao Li,Qiang Hou,Fei Chen,Zhongmin Ou,Jun-Yi Ge,Shixun Cao,Jincang Zhang 한국물리학회 2019 Current Applied Physics Vol.19 No.4
Bulk samples of K doping K2xFeTe1-xSx with x=0.07, 0.1, 0.2, 0.3 are successfully prepared by using easy-to-use stable compound K2S as the reactant. The lattice constant calculated from X-ray diffraction patterns indicate that K ions enter the Fe-Te-S layers. K doping is beneficial enhance the superconductivity transition temperature from the R-T curves. The apparent diamagnetic signal is observed in M-T curves when the content of K is smaller than 0.1. However, differential curves (dM/dT) in K-rich samples appear sharp slope mutations, which means that the Meissner effect signal is covered by the increased excess ferromagnetic ions. The number of excess Fe magnetic ions is proportional to K content, which may play an important role in determining the superconductivity.
Late-onset Quetiapine-related Tardive Dyskinesia Side Effects in a Patient with Psychotic Depression
Yi-Cheng Hou,Chien-Han Lai 대한정신약물학회 2014 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.12 No.2
The atypical antipsychotics were believed to induce less extrapyramidal syndrome, including tardive dyskinesia (TD). Since theintroduction of the quetiapine, it is also reported with less TD side effects. It even can relieve the symptoms of severe TD andreduce the risk of TD. The quetiapine’s low affinity and fast dissociation from postsynaptic dopamine D2 receptors should givethe least risk of producing the symptoms of TD. The quetiapine even can reduce the TD side effects related to clozapine, whichhas the lowest risk for TD. However, since the first case report of TD side effects related to quetiapine published on 1999,the safety of quetiapine in TD aspect has been questioned. Therefore, we want to share this case report, which was writtento describe the severe late-onset TD side effects after long-term use of quetiapine in a patient with psychotic depression. Thepatient had no significant findings after concurrent comprehensive neurological examinations, magnetic resonance imaging ofbrain and electroencephalogram since the onset of TD.
Hou Ming-Feng,Ou-Yang Fu,Li Chung-Liang,Chen Fang-Ming,Chuang Chieh-Han,Kan Jung-Yu,Wu Cheng-Che,Shih Shen-Liang,Shiau Jun-Ping,Kao Li-Chun,Kao Chieh-Ni,Lee Yi-Chen,Moi Sin-Hua,Yeh Yao-Tsung,Cheng Chi 생화학분자생물학회 2021 Experimental and molecular medicine Vol.53 No.-
In Western countries, breast cancer tends to occur in older postmenopausal women. However, in Asian countries, the proportion of younger premenopausal breast cancer patients is increasing. Increasing evidence suggests that the gut microbiota plays a critical role in breast cancer. However, studies on the gut microbiota in the context of breast cancer have mainly focused on postmenopausal breast cancer. Little is known about the gut microbiota in the context of premenopausal breast cancer. This study aimed to comprehensively explore the gut microbial profiles, diagnostic value, and functional pathways in premenopausal breast cancer patients. Here, we analyzed 267 breast cancer patients with different menopausal statuses and age-matched female controls. The α-diversity was significantly reduced in premenopausal breast cancer patients, and the β-diversity differed significantly between breast cancer patients and controls. By performing multiple analyses and classification, 14 microbial markers were identified in the different menopausal statuses of breast cancer. Bacteroides fragilis was specifically found in young women of premenopausal statuses and Klebsiella pneumoniae in older women of postmenopausal statuses. In addition, menopausal-specific microbial markers could exhibit excellent discriminatory ability in distinguishing breast cancer patients from controls. Finally, the functional pathways differed between breast cancer patients and controls. Our findings provide the first evidence that the gut microbiota in premenopausal breast cancer patients differs from that in postmenopausal breast cancer patients and shed light on menopausal-specific microbial markers for diagnosis and investigation, ultimately providing a noninvasive approach for breast cancer detection and a novel strategy for preventing premenopausal breast cancer.
Hou, Wenpeng,Zhao, Ning-Jiu,Meng, Dongli,Tang, Jing,Zeng, Yi,Wu, Yu,Weng, Yangziwan,Cheng, Chungui,Xu, Xiulai,Li, Yi,Zhang, Jian-Ping,Huang, Yong,Bielawski, Christopher W.,Geng, Jianxin American Chemical Society 2016 ACS NANO Vol.10 No.5
<P>The installation of heterojunctions on the surfaces of carbon nanotubes (CNTs) is an effective method for promoting the charge separation processes needed for CNT-based electronics and optoelectronics applications. Conjugated polymers are proven state-of-the-art candidates for modifying the surfaces of CNTs. However, all previous attempts to incorporate conjugated polymers to CNTs resulted in unordered interfaces. Herein we show that well-defined chains of regioregular poly(3-hexylthiophene) (P3HT) were successfully grown from the surfaces of multiwalled CNTs (MWNTs) using surface-initiated Kumada catalyst-transfer polycondensation. The polymerization was found to proceed in a controlled manner as chains of tunable lengths were prepared through variation of the initial monomer-to-initiator ratio. Moreover, it was determined that large-diameter MWNTs afforded highly ordered P3HT aggregates, which exhibited a markedly bathochromically shifted optical absorption due to a high grafting density induced planarization of the polymer chains. Using ultrafast spectroscopy, the heterojunctions formed between the MWNTs and P3HT were shown to effectively overcome the binding energy of excitons, leading to photoinduced electron transfer from P3HT to MWNTs. Finally, when used as prototype devices, the individual MWNT-g-P3HT core-shell structures exhibited excellent photoresponses under a low illumination density.</P>
Exploring Information Warfare Strategies during the Russia–Ukraine War on Twitter
Shu–Min Hou,Wen-Cheng Fu,Shao–Yi Lai 한국국방연구원 2023 The Korean Journal of Defense Analysis Vol.35 No.1
Twitter, one of the mainstream social media platforms, has played a significant role in strategic communication and public diplomacy. Using tweets during the 2022 Russia–Ukraine war period as a case study, the researchers aim to build a pipeline that automatically detects information manipulation. Artificial intelligence and machine learning technology are adopted to target certain coordinated groups of people, and how they manipulate online public opinion internationally via social media platforms by retweeting identical tweets between members within the groups and even with their own tweets. With the large number of tweets posted and retweeted by the coordinated groups, their intended content will appear in the news feeds of normal users. This study maps an approach to future warfare that social media is becoming a vital part of information warfare to influence the results of conflict and regional relationships. The researchers argue that the government should consider taking countermeasures: 1) Set up legislation regarding media platforms and cooperate with social media companies to monitor manipulating behaviors. 2) Establish a model to orchestrate inter-agency defensive strategies. 3) Increase people’s media literacy to allow them to be aware of manipulative and collaborative behavior and decrease their likeliness to spread fake/manipulated information online unintentionally. Also, similar research can be adapted to different regional conflicts.
Designing Redox-Stable Cobalt-Polypyridyl Complexes for Redox Flow Batteries
변혜령,( Chunzhen Yang ),( Goergiog Nikiforidis ),박지영,최종훈,( Yong Luo ),( Liang Zhang ),( Shi-cheng Wang ),( Yi-tsu Chan ),( Zhaomin Hou ),백무현,이윤호 한국공업화학회 2018 한국공업화학회 연구논문 초록집 Vol.2018 No.0
We developed rational strategies for exploiting two common principles in organometallic chemistry for enhancing the robustness of pseudo-octahedral Co-polypyridyl complexes. Namely, the spin-crossover between low and high-spin states and the chelation effect emerging from replacing three bidentate ligands with two tridentate analogues. Quantum chemical models are used to conceptualize our approach and make predictions that are tested against experiments by preparing prototype Co-complexes and profiling them as catholytes and anolytes. In good agreement with the conceptual predictions, very stable cycling performance over 600 charge cycles is found.
A bi-directional valveless piezoelectric micropump based on the Coanda effect
Zheng Zhang,Lipeng He,Jianwen Zhou,Dianbin Hu,Yi Hou,Guangming Cheng 대한기계학회 2023 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.37 No.2
In this paper, the hydrodynamic characteristics of a piezoelectric micropump operate on the Coanda effect, and the mechanism of bi-directional pumping are analyzed by numerical simulation and experiments. The research focuses on the different positions of the fluid deflector and the influence on the output of the micropump. The results show that a closer fluid deflector to the inlet can produce greater vortices in the suction process due to the Coanda effect, and the backflow diminishing is more significant as well. Moreover, the different positions of the fluid deflector can cause a phenomenon that the micropump will achieve bi-directional pumping. As a finding, vortices arranged in pairs could improve the rectification efficiency of the micropump. The micropump achieves a maximum flow rate of 40.5 ml/min and back pressure of 5.76 cmH 2 o. In addition, the maximum flow rate per unit area can reach 305.2 μl/(min mm 2 ).