RISS 학술연구정보서비스

검색
다국어 입력

http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.

변환된 중국어를 복사하여 사용하시면 됩니다.

예시)
  • 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
  • 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
닫기
    인기검색어 순위 펼치기

    RISS 인기검색어

      검색결과 좁혀 보기

      선택해제
      • 좁혀본 항목 보기순서

        • 원문유무
        • 원문제공처
          펼치기
        • 등재정보
          펼치기
        • 학술지명
          펼치기
        • 주제분류
          펼치기
        • 발행연도
          펼치기
        • 작성언어

      오늘 본 자료

      • 오늘 본 자료가 없습니다.
      더보기
      • 무료
      • 기관 내 무료
      • 유료
      • S-412 Genetic Variants Associated with Sarcopenia in Elderly Koreans

        ( Ye Seul Yang ),( Soo Heon Kwak ),( Myeong Jae Chun ),( Heejin Jin ),( Young Min Cho ),( Hye Seung Jung ),( Nam H. Cho ),( Hak Chul Jang ),( Kyong Soo Park ) 대한내과학회 2016 대한내과학회 추계학술발표논문집 Vol.2016 No.1

        Objective:?Sarcopenia, the progressive decrease of skeletal muscle mass and function, is related to functional impairment in the elderly. Muscle mass, mainly composed of appendicular lean mass (ALM), is known to be a heritable trait. Sarcopenia has been a subject of increasing genetic research. However, genetic risk factors in Asian were not thoroughly evaluated. The aim of this study is to identify genetic variants associated with sarcopenia defined by the Foundation for the National Institutes of Health in Korean adults over 65 years old.?Methods:?A total of 1,290 individuals from Ansung cohort was investigated. Sarcopenia was defined as the lowest quantile of ALM adjusted for body mass index (BMI) of the population studied and 254 participants met this criteria. Affymetrix Genome-Wide Human Single Nucleotide Polymorphism (SNP) Array 5.0 was used for genotyping and 308,945 SNP markers passed quality control filter. We performed logistic regression analysis including sex, age and BMI as covariates. Arbitrarily defined?P?value threshold of less than 0.00001 was used for suggestive evidence of association.?Results:?None of the SNP markers passed genome-wide significance threshold of?P?<5×10-8. A variant in SORCS2?(rs6834325), was most significantly associated with sarcopenia in elderly Koreans (odds ratio 0.58, 95% confidence interval=[0.46, 0.72],?P?= 1.50×10-6). Eight other variants had suggestive association and were considered to be functionally relevant to sarcopenia; seven of those including rs2329489 in/near?GRB10?with odds ratio ranging from 1.57 to 1.62 and?P?from 8.49×10-5?to 3.82×10-5, and rs16958069 (0.64, 3.99×10-5) in?RYR3. Among known candidate genes, several variants in?GREM1,?ST18,?MMP?and?INSR?showed nominal significance of?P?<0.05.?Conclusions:?We have identified nine suggestive genetic loci associated with sarcopenia in elderly Korean. As we had limited statistical power due to small sample size, further replication study is required to validate our findings.

      • SCIESCOPUSKCI등재

        Physics analysis of new TRU recycling options using FCM and MOX fueled PWR assemblies

        Cho, Ye Seul,Hong, Ser Gi Korean Nuclear Society 2020 Nuclear Engineering and Technology Vol.52 No.4

        In this work, new multi-recycling options of TRU nuclides using PWR fuel assemblies comprised of MOX and FCM (Fully Ceramic Micro Encapsulated) fuels are suggested and neutronically analyzed. These options do not use a fully recycling of TRU but a partial recycling where TRUs from MOX fuels are recycled while the ones from FCM fuels are not recycled due to their high consumption rate resulted from high burnup. In particular, additional external TRU feed in MOX fuels for each cycle was considered to significantly increase the TRU consumption rate and the finally selected option is to use external TRU and enriched uranium feed as a makeup for the heavy metal consumption in MOX fuels. This hybrid external feeding of TRU and enriched uranium in MOX fuel was shown to be very effective in significantly increasing TRU consumption rate, maintaining long cycle length, and achieving negative void reactivity worth during recycling.

      • KCI등재

        Screening Tool for Anxiety Disorders: Development and Validation of the Korean Anxiety Screening Assessment

        Ye-seul Kim,Yeon-soo Park,Gyeong-cheol Cho,Ki-ho Park,Shin-Hyang Kim,Seung Yeon Baik,Cho Long Kim,Soo-yun Jung,Won-Hye Lee,Youn-young Choi,Seung-Hwan Lee,Kee-Hong Choi 대한신경정신의학회 2018 PSYCHIATRY INVESTIGATION Vol.15 No.11

        Objective This study evaluated the psychometric properties of the Korean Anxiety Screening Assessment (K-ANX) developed for screening anxiety disorders. Methods Data from 613 participants were analyzed. The K-ANX was evaluated for reliability using Cronbach’s alpha, item-total correlation, and test information curve, and for validity using focus group interviews, factor analysis, correlational analysis, and item characteristics based on item response theory (IRT). The diagnostic sensitivity and specificity of the K-ANX were compared with those of the Beck Anxiety Inventory (BAI) and Generalized Anxiety Disorder 7-item scale (GAD-7). Results The K-ANX showed excellent internal consistency (α=0.97) and item-total coefficients (0.92–0.97), and a one-factor structure was suggested. All items were highly correlated with the total scores of the BAI, GAD-7, and Penn State Worry Questionnaire. IRT analysis indicated the K-ANX was most informative as a screening tool for anxiety disorders at the range between 0.8 and 1.6 (i.e., top 21.2 to 5.5 percentiles). Higher sensitivity (0.795) and specificity (0.937) for identifying anxiety disorders were observed in the K-ANX compared to the BAI and GAD-7. Conclusion The K-ANX is a reliable and valid measure to screen anxiety disorders in a Korean sample, with greater sensitivity and specificity than current measures of anxiety symptoms.

      • KCI등재

        교사효능감이 직무스트레스에 미치는 영향에서 교사가 인식한 어린이집 조직풍토의 매개효과

        조예슬 ( Cho Ye Seul ),김지연 ( Kim Ji Yeon ) 한국유아교육학회 2021 유아교육연구 Vol.41 No.4

        본 연구는 교사효능감이 직무스트레스에 미치는 영향에서 교사가 인식한 어린이집 조직풍토의 매개효과를 검증하고자 하였다. 연구 대상은 서울, 경기, 인천 지역에 소재한 어린이집에 재직 중인 보육교사 454명이다. 수집된 자료의 분석을 위해 SPSS 26.0과 PROCESS macro ver.3.5 프로그램을 이용하여 상관분석, 위계적 회귀분석, 매개효과 검증 및 부트스트래핑을 실시하여 통계적 유의성을 검증하였다. 연구 결과 첫째, 직무스트레스는 교사효능감, 어린이집의 조직풍토와 부적으로 유의한 상관관계가 나타났다. 둘째, 교사효능감과 어린이집의 조직풍토는 직무스트레스에 부적 영향을 미치는 것으로 나타났다. 셋째, 교사효능감은 어린이집의 조직풍토를 매개로 하여 직무스트레스에 간접적인 영향을 주는 것으로 확인되었다. 결론적으로 교사의 직무스트레스 완화를 위해서는 교사가 높은 효능감을 가지고 어린이집의 조직풍토를 긍정적으로 인식하는 것이 중요함을 밝혔다는 점에서 의의를 가진다. The purpose of this study was to verify the mediating effect of organizational climate of the childcare center perceived by teachers in the relationship between teacher efficacy and job stress. The participants of this study were 454 teachers working in childcare centers located in Seoul, Gyeonggi, and Incheon. The collected data were analyzed by using correlation, hierarchical regression, bootstrapping via SPSS 26.0, and PROCESS macro ver.3.5 program. The results of this study are as follows. First, job stress had a negative correlation with teacher efficacy and organizational climate. Second, teacher efficacy and organizational climate had a significant effect on job stress. Third, teacher efficacy had an indirect effect on job stress through the organizational climate of the childcare center. In conclusion, in order to relieve job stress, it is important for teachers to possess a high level of efficacy and to positively recognize the organizational climate of the childcare center.

      • FC 2-7 : Elevated KAI1 protein expression identified in malignant melanoma

        ( Ye Seul Kim ),( Ji Hoon Sim ),( Sang Jin Oh ),( Je Min An ),( Sang Hoon Lee ),( Sung Yul Lee ),( Moon Kyun Cho ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2

        Background: KAI1/CD82 reportedly slows the metastatic process in a variety of tumors. However, its function is not fully clear. This study investigates the expression of KAI1 in correlation with malignant skin cancers. Objectives: To investigate the expression and clinical significance of KAI1 protein in malignant skin cancers. Methods: KAI1/CD82 expression was evaluated by western blotting in 24 specimens including 6 malignant melanoma (MM), 6 squamous cell carcinoma (SCC), 6 BCC and 6 normal skin specimens. Immunohistochemical staining was performed to measure KAI1/CD82 expression in 6 MM, 6 SCC and 6 BCC. Results: We observed over-expression of KAI1 in the malignant melanoma. The expressions of KAI1 in malignant melanoma were higher than those in SCC and BCC. The KAI1 expressions in malignant melanoma were higher in protein levels compared to SCC and BCC. Western blotting results agreed with immunohistochemistry. Conclusion: KAI1 is highly related to malignant melanoma and may be a useful indicator of malignant melanoma.

      • KCI등재

        Motivational Interviewing Training Using Role Play in Dental Hygiene Students

        Ye Seul Han,Young-Sik Cho 한국치위생과학회 2018 치위생과학회지 Vol.18 No.1

        The purpose of this study was to develop a motivational interviewing (MI) training program to improve competency in communication and to effect the evaluated changes that would occur in dental students’ counseling techniques as result of the training in the program. The study proceeded through the program via role-play practice, which was explained effectively during the MI program training process. A convenience sample of 43 fourth-year dental hygiene students was recruited. Twenty-two students were randomly assigned to the intervention group and 21 to the control group in the order of recruitment. The theoretical lecture was delivered over 3 hours and the practice was done in parallel by applying cases occurring in clinic settings. The practice was technical training, partner practice, and small group practice. The intervention group received three hour MI lecture while the control group received no lecture. Evaluation through role-play practice was separated according to “researcher’s viewpoint,” “counselor’s role viewpoint,” and “patient’s role viewpoint.” The results of the analysis showed that the intervention group had higher MI skills and ability than the control group. Furthermore, program participants showed positive impressions to the MI training program. The use of coaching sessions improved the MI techniques and counseling skills of dental hygiene students learning MI. The effect of the application of the MI training program was that the MI training improved counseling skills and interviewing abilities. Moreover, continuous training and feedback enhanced MI techniques and core skills. Training using lectures in parallel with practice rather than education through theory alone improved students’ techniques. Application of role play through the combined method of the MI program was confirmed by an effective training method.

      • SCISCIESCOPUS

        The external benefits of expanding the micro photovoltaic power generation in Korea: A contingent valuation study

        Cho, Yong-Cheol,Lim, Seul-Ye,Yoo, Seung-Hoon Elsevier 2017 SOLAR ENERGY -PHOENIX ARIZONA THEN NEW YORK- Vol.158 No.-

        <P><B>Abstract</B></P> <P>The micro photovoltaic (MPV) is a good alternative for reducing greenhouse gas (GHG) emissions in the residential areas. Therefore, the Korean government has planned to expand the MPV power generation from about 2000 households (6MW) in 2014 to 25,000 households (61MW) by 2017. This article aims to assess the external benefits of this expansion in terms of reducing GHG emissions. To this end, we derive the public’s additional willingness to pay (WTP) for the expansion through an increase in electricity bill using a contingent valuation survey of 1000 Korean households. For the purpose of mitigating the response effect in eliciting their WTP and increasing statistical efficiency in analyzing the WTP data, we employ a one-and-one-half-bounded dichotomous choice question format. Furthermore, we use the spike model so as to model zero WTP responses. The mean additional WTP for the expansion is computed to be KRW 15.48 (USD 0.01) per kWh. This value amounts to 12.4% of the residential electricity price, KRW 125.14 (USD 0.11). We can conclude that Korean households are ready to shoulder some of the financial burden of expanding the MPV power generation.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Korea plans to expand micro photovoltaic (MPV) power generation from 6MW to 61MW. </LI> <LI> We assess the external benefits of this expansion using contingent valuation. </LI> <LI> We elicit the additional willingness to pay (WTP) for expanding MPV power generation. </LI> <LI> The mean additional WTP is estimated to be KRW 15.48 (USD 0.01) per kWh. </LI> <LI> This value amounts to 12.4% of the residential electricity price. </LI> </UL> </P>

      연관 검색어 추천

      이 검색어로 많이 본 자료

      활용도 높은 자료

      해외이동버튼