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Singh, Vikas Kumar,Upadhyay, Priti,Sinha, Pallavi,Mall, Ashish Kumar,Ellur, Ranjith K.,Singh, Atul,Jaiswal, Sanjay K.,Biradar, Sunil,Ramakrishna, S.,Sundaram, R.M.,Ahmed, Ilyas,Viraktamath, B.C.,Kole, 한국작물학회 2011 Journal of crop science and biotechnology Vol.14 No.1
A total of six TGMS (thermosensitive genic male sterile lines) and nine pollinator lines were subjected to molecular characterization using 48 genome-wide SSR (simple sequence repeat) markers. Cluster analysis revealed clear differentiation among the TGMS lines according to their source of origin. The SSR-based genetic distance between the hybrids of the parental lines ranged from 0.36 to 0.79 suggesting a high degree of genetic divergence. Among a set of 54 hybrids generated using parental lines, 32 showed better parent heterosis (+21.7%) while 19 showed mid-parent heterosis (+15.0%). For the trait yield per plant genetic distance (GD) was negatively correlated with $F_1$ performance (r = -0.202), mid-parent heterosis (r = $-0.325^*$; P < 0.05), and better parent heterosis (r = -0.261), while it was positively correlated with specific combining ability (r = 0.042). Based on the grouped genetic distance (GGD), the hybrid combinations were divided into four groups. The GGD showed linear correlation with hybrid performance within the group (GGD = 40 - 50: r = -0.07; GGD = 70 - 80: r = 0.32). This information can be utilized in the development of higher yielding, two-line rice hybrids through selection of intermediately diverse parental lines using GGD.
Vikas Kumar Singh,Priti Upadhyay,Pallavi Sinha,Ashish Kumar Mall,Ranjith K. Ellur,Atul Singh,Sanjay K.Jaiswal,Sunil Biradar,S. Ramakrishna,R.M. Sundaram,Ilyas Ahmed,B. C. Viraktamath,C. Kole,Sukhpal S 한국작물학회 2011 Journal of crop science and biotechnology Vol.14 No.1
A total of six TGMS (thermosensitive genic male sterile lines) and nine pollinator lines were subjected to molecular characterization using 48 genome-wide SSR (simple sequence repeat) markers. Cluster analysis revealed clear differentiation among the TGMS lines according to their source of origin. The SSR-based genetic distance between the hybrids of the parental lines ranged from 0.36to 0.79 suggesting a high degree of genetic divergence. Among a set of 54 hybrids generated using parental lines, 32 showed better parent heterosis (+21.7%) while 19 showed mid-parent heterosis (+15.0%). For the trait yield per plant genetic distance (GD) was negatively correlated with F1 performance (r = -0.202), mid-parent heterosis (r = -0.325*; P < 0.05), and better parent heterosis (r = -0.261), while it was positively correlated with specific combining ability (r = 0.042). Based on the grouped genetic distance (GGD),the hybrid combinations were divided into four groups. The GGD showed linear correlation with hybrid performance within the group (GGD = 40 - 50: r = -0.07; GGD = 70 - 80: r = 0.32). This information can be utilized in the development of higher yielding,two-line rice hybrids through selection of intermediately diverse parental lines using GGD.
Kumar Arun,Kumar Vikas,Akhouri Vivek,Kumar Ranjit,Ali Mohammad,Rashmi Tuhin,Chand Gyanendra Bahadur,Singh Sushil Kumar,Ghosh Ashok Kumar 한국독성학회 2022 Toxicological Research Vol.38 No.4
Arsenic poisoning in ground water is one of the most sensitive environmental pollutant causing serious pollution all over the world. Chronic arsenic exposure through drinking water to humans leads to major public health related issues. There have been very meagre studies which reported that, the plant constituents proved to exhibit protective effect from arsenicosis. Therefore, the present study aims to evaluate the protective efficacy of Coriandrum sativum seeds extract against sodium arsenite induced toxicity in Swiss albino mice. In the present study twenty-four male healthy Swiss albino mice (30 ± 5 g) were divided into four groups (n = 6), where the control group received normal diet and water; group II and group III treated with sodium arsenite (2 mg per kg body weight per day) for 2 and 4 weeks respectively. The group IV mice were administered with C.sativum seeds extract at the dose of 150 mg per kg body weight per day for 4 weeks upon sodium arsenite pretreated (2 mg/kg body weight for 4 weeks per day) mice. After the complete dose duration, all the treatment group animals were sacrificed same day for haematological, biochemical and histopathological study. In the arsenic treated mice, there were significant (p < 0.0001) changes in the serum levels of ALT, AST, ALP, urea, uric acid and creatinine as well as in the haematological parameters. In contrast, after the administration with C.sativum seeds extract upon arsenic pretreated mice, there was significant (p < 0.0001) improvement observed in the hepatic and renal biomarker parameters as well as haematological variables. In the arsenic intoxicated mice, after administration with C.sativum seeds extract there was significant (p < 0.0001) reduction in the arsenic concentration in blood, liver and kidney tissues as well as in the serum LPO levels. Furthermore, the histopathological study showed that, C.sativum seeds extract administrated group of mice significantly restored the liver and kidney at cellular level against arsenic induced toxicity. The entire study concludes that C.sativum seeds extract possesses the ameliorative effect against arsenic induced liver and kidney intoxication.
Kumar, Parmod,Sharma, Vikas,Singh, Jitendra P.,Kumar, Ashish,Chahal, Surjeet,Sachdev, K.,Chae, K.H.,Kumar, Ashok,Asokan, K.,Kanjilal, D. Elsevier 2019 Journal of magnetism and magnetic materials Vol.489 No.-
<P><B>Abstract</B></P> <P>Present work aims at investigating the structural, magnetic and dielectric properties of zinc doped Fe<SUB>2</SUB>O<SUB>3</SUB> nanoparticles (pure, 10%, 20% & 30%) and correlated with their local electronic structures using X-ray absorption near-edge structure (XANES) spectroscopy. X-ray diffraction and Raman measurements infer that doping of Zn cations lead to the formation of secondary phases corresponding to ZnFe<SUB>2</SUB>O<SUB>4</SUB> along with the hematite phase of Fe<SUB>2</SUB>O<SUB>3</SUB>. Magnetic measurements show that magnetization vs magnetic field curve for 10% Zn doping exhibit maximum saturation magnetization (~2.93 × 10<SUP>−3</SUP> emu/g) as well as the coercivity (~956 Oe). The values of these parameters decrease for higher content of Zn. The temperature dependence of dielectric behaviour follows the same trend as that of the lattice parameter and magnetic measurements. The XANES spectra at Fe L- and Fe K-edges indicate partial reduction of Fe<SUP>3+</SUP> ions into Fe<SUP>2+</SUP> upon Zn doping in the Fe<SUB>2</SUB>O<SUB>3</SUB> lattice. However, divalent state is favourable for Zn (i.e. Zn<SUP>2+</SUP>) within the doping range reported in this study.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Zn doped Fe<SUB>2</SUB>O<SUB>3</SUB> nanoparticles. </LI> <LI> Study of magnetic and electrical properties. </LI> <LI> Correlation of magnetic and electrical properties with local electronic structure. </LI> </UL> </P>
Singh, Vijay,Singh, N.,Dubey, Vikas,Singh, Pramod K.,Shinde, K.N.,Ravi Kanth Kumar, V.V. Elsevier 2018 OPTIK -STUTTGART- Vol.158 No.-
<P><B>Abstract</B></P> <P>Ce<SUP>3+</SUP>-doped CaAl<SUB>12</SUB>O<SUB>19</SUB> phosphors with different Ce<SUP>3+</SUP> contents, as well as those with Mg<SUP>2+</SUP> codoped powders, were successfully synthesized using a rapid combustion method (<5 min) for this paper. The powders were well characterized by the X-ray diffraction (XRD) and photoluminescence (PL) techniques. The emission measurements upon a UV-light excitation (262 nm) showed the emission characteristics of the Ce<SUP>3+</SUP> ion that are due to the 5d–4 f transitions. The emission and excitation spectra were recorded as the Ce<SUP>3+</SUP> concentration was kept constant and the Mg<SUP>2+</SUP> concentration was varied. It became evident that the addition of the Mg<SUP>2+</SUP> along with the Ce<SUP>3+</SUP> resulted in increases of the PL intensity, and the reasons for this behavior are discussed.</P>
Sharma, Vikas Kumar,Singh, Sanjay Kumar,Singh, Umesh The Korean Statistical Society 2017 Communications for statistical applications and me Vol.24 No.3
The power Lindley distribution with some of its properties is considered in this article. Maximum likelihood, least squares, maximum product spacings, and Bayes estimators are proposed to estimate all the unknown parameters of the power Lindley distribution. Lindley's approximation and Markov chain Monte Carlo techniques are utilized for Bayesian calculations since posterior distribution cannot be reduced to standard distribution. The performances of the proposed estimators are compared based on simulated samples. The waiting times of research articles to be accepted in statistical journals are fitted to the power Lindley distribution with other competing distributions. Chi-square statistic, Kolmogorov-Smirnov statistic, Akaike information criterion and Bayesian information criterion are used to access goodness-of-fit. It was found that the power Lindley distribution gives a better fit for the data than other distributions.
A Study of Antibacterial Activity of Some Novel 8-Methoxy-4-methyl-quinoline Derivatives
Singh, Sheoraj,Kumar, Vikas,Kumar, Ashok,Sharma, Shalabh,Dua, Piyush Korean Chemical Society 2010 Bulletin of the Korean Chemical Society Vol.31 No.12
In the present study, some quinoline derivatives have been synthesized like 8-methoxy-4-methyl-2-amino-(3'-chloro-2'-oxo-4'-substituted aryl-1'-azetidinyl)quinolines 8-12 and 8-methoxy-4-methyl-2-amino-(2'-substituted aryl-4'-oxo-1',3'-thiazolidin-3'-yl) quinolines 13-17 from 8-methoxy-4-methyl-2-(substituted arylidenyliminoamino)-quinolines 3-7. The structural assignments of these compounds were based on spectral (IR, $^1H$-NMR, Mass) and elemental (C, H, N) analysis. Further, these compounds were evaluated for antibacterial activity against various bacterial strains. Three compounds 10, 11 and 16 were found to exhibit potent antibacterial activity as compared to the standard drug amphicillin.
Vikas Kumar,Raghubansh K. Singh,Pradip Chowdhury 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.67 No.-
This work highlights extraction and removal of Lignosulfonate using sunflower oil-Tri-n-octylamine (TOA) system in bulk liquid membrane transport. Maximum extraction and recovery percentages of 92.4% and 75.2% were achieved. Optimum manifold operating conditions were: 4 vol.% TOA, 2 ± 0.1 feed phase pH, 300 rpm stirring speed, at 40 °C with 0.2 (M) Na2SO4 solution. 1:2 (organic/aqueous) and 1:1 (aqueous/aqueous) phase ratios produced best results. Extraction (36.85 kJ/mol) was found to be intermediate controlled and stripping (54.79 kJ/mol) was chemical reaction controlled. Kinetic estimation of data with higher rate constants for stripping vis-à-vis extraction showed latter to be rate determining.
Primary pyomyositis in North India: a clinical, microbiological, and outcome study
( Susheel Kumar ),( Ashish Bhalla ),( Rajveer Singh ),( Navneet Sharma ),( Aman Sharma ),( Vikas Gautam ),( Surjit Singh ),( Subhash Varma ) 대한내과학회 2018 The Korean Journal of Internal Medicine Vol.33 No.2
Background/Aims: Pyomyositis is an infective condition with primary involvement of the skeletal muscles. There is sparse recent literature on patients with pyomyositis. Methods: This study was carried out at emergency services of a tertiary care center located in subtropical area of Indian subcontinent. Results: Sixty-two patients of primary pyomyositis formed the study cohort. Mean age of occurrence was 29.9 ± 14.8 years. There were 54 men. Twelve patients had underlying medical diseases. Muscle pain was seen in all 62 patients. Forty-eight patients (77.4%) had the fever. Most common site of involvement was thigh muscles (n = 29, 46.8%). Forty-nine patients (79%) presented in the suppurative stage of illness. Patients with comorbidities were older (age: median 36 years [interquartile range (IQR), 25 to 47] vs. 24 years [IQR, 16 to 35], p = 0.024), had higher culture positivity with gram-negative organisms (8/9 [88.89%] vs. 6/29 [20.69%], p = 0.001). Importantly, higher number of these patients received inappropriate antibiotics initially. Patients with positive pus culture result had higher complication rate (32/38 [84.21%] vs. 10/18 [55.56%], p = 0.044). Six patients (9.7%) had in-hospital mortality. Lower first-day serum albumin, initial inappropriate antibiotic therapy, and advanced form of the disease at presentation were associated with increased in-hospital mortality. Conclusions: Primary pyomyositis is not an uncommon disease entity. Patients with comorbidities were more likely to receive initial inappropriate antibiotic therapy. Patients with positive pus culture report had the higher rate of complications. Lower first-day serum albumin, initial inappropriate antibiotic therapy and advanced form of the disease at presentation were associated with increased in-hospital mortality.