Genome-wide investigation of a Korean synthetic breed, Woori-Heukdon using the Illumina PorcineSNP60K BeadChip

Yong‑Min Kim,Ha‑Seung Seong,Jung‑Jae Lee,Da‑Hye Son,Jin‑Su Kim,Soo‑Jin Sa,Young‑Sin Kim,Tae‑Jeong Choi,Kyu‑Ho Cho,Joon‑Ki Hong,Jung‑Woo Choi,Eun‑Seok Cho 한국유전학회 2020 Genes & Genomics Vol.42 No.12

Background: Woori-Heukdon (KWH) is a Korean synthetic pig breed generated using Chookjin-Duroc (KCD), Chookjin-Chamdon (KCC), and their crossbreds. Currently, there is a severe lack of studies investigating the Korean breed populations including wild boars (KWB) throughout the genome. Objective: This study was performed to investigate the genetic characteristics of Korean pig populations at the genome-wide level. Methods: Using the SNP dataset derived from genotyped and downloaded datasets using the Illumina PorcineSNP60K BeadChip, we compared the genomes of 532 individuals derived from 23 pig breeds to assess the genetic diversity, inbreeding coefficient, genetic differentiation, and population structure. Results: KWB showed the lowest average expected heterozygosity (HE = 0.1904), while KWH showed the highest genetic diversity (HE = 0.02859) among Korean populations. We verified that the genetic composition of KWH, showing USD of 74.8% and KCC of 25.2% in ADMIXTURE analysis. In population structure analyses, KCC was consistently shown to be separated from other pig populations. In addition, we observed gene flow from Western pigs to a part of Chinese populations. Conclusion: This study showed that Korean native pigs, KCC have genetic differences in comparison with Chinese and Western pigs; despite some historical records and recent genetic studies, we could not find any clear evidence that KCC was significantly influenced by Chinese or Western breeds in this study. We also verified the theoretical genomic composition of KWH at the molecular level in structure analyses. To our knowledge, this is the first genomic study to investigate the genomic characteristics of KWH and KCC.

소집단 운동활동이 훈련가능 정신지체 학생의 사회적 상호작용에 미치는 효과

조용태 대진대학교 교육연구소 2000 교육연구 Vol.2 No.1

The purpose of this research was invested the effect of small=group motor activities on social interaction of students with mental retardation. The subjects of this research were 9 trainable mental retardation students selected in special school for mentally retarded child. This research found that the most significant effect of small-group motor activities on social interaction, particularly share benaciors, of students with trainable mental retardation. However, play organizer behavior into social interaction found significant improving effect.

開放體制大學 敎育政策의 評價準據模型 探索

趙鏞泰,嚴益命 대구효성가톨릭대학교 교육연구소 1993 교육연구논집 Vol.2 No.-

This sutdy is designed to investigate for model of assessment standards, this is, assessment indications and methods in educational policy of open system university. For the purpose of, this study used the availible sundry records bibliography, the previous research articles, and the statistical report. This study fromed the assessment standard model by method of three-dimendsional structure shapes from Systematic Theory point of view. Assessment factors come within the subject of assessment maked disposition at the one-dimensional structure shape, phases of systematic approach maked disposition at the two-dimensional structure shape, and circumstance in every phases maked disposition at the three-dimensional structure shape. And with this model as the central figure, this study formed assessment standards and factors all phases. Divide into phases for assessment standards, there are appropriatness and lawfulness in the phase of in-put, efficiency, democracy, opening to the public, accountability in the phase of transaction, and effectiveness and responsiveness in the phase of out-put. Assessment indications breaks into parts on the basis of assessment factors. Assessment factors divided into educational goals, curriculums, instructors, students, equipment and facilities, organizations and public administration, and finances in the open system university and relation between the open system university and local community. Then this study gave an account of those assessment methods.

Case Report : Improved severe hepatopulmonary syndrome after Liver transplantation in an adolescent with end-stage Liver disease secondary to biliary atresia

( Tae Jun Park ),( Keun Soo Ahn ),( Yong Hoon Kim ),( Hyungseop Kim ),( Ui Jun Park ),( Hyoung Tae Kim ),( Won Hyun Cho1 ),( Woo Hyun Park ),( Koo Jeong Kang ) 대한간학회 2014 Clinical and Molecular Hepatology(대한간학회지) Vol.20 No.1

Hepatopulmonary syndrome (HPS) is a serious complication of end-stage liver disease, which is characterized by hypoxia, intrapulmonary vascular dilatation, and liver cirrhosis. Liver transplantation (LT) is the only curative treatment modality for patients with HPS. However, morbidity and mortality after LT, especially in cases of severe HPS, remain high. This case report describes a patient with typical findings of an extracardiac pulmonary arteriovenous shunt on contrast-enhanced transesophageal echocardiography (TEE), and clubbing fingers, who had complete correction of HPS by deceased donor LT. The patient was a 16-year-old female who was born with biliary atresia and underwent porto-enterostomy on the 55th day after birth. She had been suffered from progressive liver failure with dyspnea, clubbing fingers, and cyanosis. Preoperative arterial blood gas analysis revealed severe hypoxia (arterial O2 tension of 54.5 mmHg and O2 saturation of 84.2%). Contrast-enhanced TEE revealed an extracardiac right-to-left shunt, which suggested an intrapulmonary arteriovenous shunt. The patient recovered successfully after LT, not only with respect to physical parameters but also for pychosocial activity, including school performance, during the 30-month follow-up period. (Clin Mol Hepatol 2014;20:76-80)

서남해안 지방에서 발생한 Vibrio vulnificus 감염의 임상적 고찰

조남수,김춘호,김성중,김용배,조수형,안태훈 大韓應急醫學會 1999 대한응급의학회지 Vol.10 No.2

Background: V. vulnificus infection in found between May and October when the man who has hepatic disorder or immunity disorder eats raw shellfish and it causes the systemic symptoms such as sudden fever, chilling, shock and stupor and local skin lesions like bleb and necrosis. This disease has 46∼61% of fatality rate in spite of intensive treatment. This study conducts the examination of history, epidemic study, ingesting raw fish and bacteriologic investigation in the patients with similar clinical symptoms to the above and examines the diagnostic dorrelations. Method: It is conducted with 31 cases who admitted at emergency medical center of Chosun University Hospital from May of 1995 to September of 1998 and are suspected to have V.vulnificus infection. It analyze bacteriologic examination, the survey of residence, eating raw shellfish, hepatic disorder, alcohol drinking habits and skin lesion. Results: 1) The rate of male and female is 15.5:1 and in the age, 18 cases are in fifties, seven are in forties and six are over sixties. 2) Clinically, V.vulnificus is detected in 20 of 31 cases which is suspected to have V.vulnificus infection and it is not detected in 5 cases. Other bacteria are detected in 6 cases and they include staphylococcus aureus, pseudomonas species, β-hemolytic streptococcus and E-coil. 3) In local distribution, Kohung has 10 cases, Shinan and Mokpo have six, Haenam and Kangjin have five, Yongkwang and Muan have five, Naju and Yongam have five and Kwangju has one. 4) Eating fishes and raw shellfishes is found in 31 cases. In the kind of shellfishes, eating raw clam is 10 cases, raw thin-shelled surf calm is 8 cases, raw oyster is 5 cases and sliced raw fish is 4 cases and pickled sea foods are 4 cases. 5) The cases with hepatic disorder are 23 and 15 cases with heavy alcohol drinking Carrier are included. The cases with Diabetic Mellitus are four and those with pulmonary tuberculosis are two. Two cases have not basal diseases. 6) On the opinion of skin lesion, 20 cases show vesicular necrosis, 7 cases have dendriform erythema, 3 cases have papule and one case doesn't show clear skin lesion. Conclusion: When V.vulnificus infection is detected, it is fatal and those who have hepatic disorder or heavy alcohol drinking habit must avoid eating fishes and shellfishes raw in summer. It is important to have emergency treatment for the patient whose V.vulnificus infection is suspected. It is considered that the administration of initial antibiotics is effective by generalizing the clinical symptom, epidemic opinion and patient history even before the results of bacteriologic confirmed.

서울 성동구 지역 미세먼지의 화학적 조성에 관한 연구

조용성,이홍석,김윤신,이종태,박진수 한국환경과학회 2003 한국환경과학회지 Vol.12 No.6

To investigate the chemical characteristics of PM_(2.5) in Seoul, Korea, atmospheric particulate matters were collected using a PM_(10) dichotomous sampler including PM_(10) and PM_(2.5) inlet during the period of October 2000 to September 2001. The Inductively Coupled Plasma-Mass Spectromety (ICP-MS), Ion Chromatography (IC) methods were used to determine the concentration of both metal and ionic species. A statistical analysis was performed for the heavy metals data set using a principal component analysis (PCA) to derived important factors inherent in the interactions among the variables. The mean concentrations of ambient PM_(2.5) and PM_(10) were 24.47 and 45.27 ㎍/m³, respectively. PM2 5 masses also showed temporal variations both yearly and seasonally. The ratios of PM_(2.5)/PM_(10) was 0.54, which similar to the value of 0.60 in North America. Soil-related chemical components (such as Al, Ca, Fe, Si, and Mn) were abundant in PM_(10), while anthropogenic components (such as As, Cd, Cr, V, Zn and Pb) were abundant in PM_(2.5). Total water soluble ions constituted 30~50 % of PM_(2.5) mass, and sulfate, nitrate and ammonium were main components in water soluble ions. Reactive forms of NH₄^(+) were considered as NH₄NO₃ and (NH₄)₂SO₄ during the sampling periods. In the results of PCA for PM_(2.5), we identified three principal components. Major contribution to PM_(2.5) seemed to be soil, oil combustion, unidentified source. Further study, the detailed interpretation of these data will need efforts in order to identify emission sources.

소규모 하천 수질 예측을 위한 Computer Program(I)

趙容璡,全太誠 충주대학교 1997 한국교통대학교 논문집 Vol.32 No.2

There are many computer modeling programs for the river and lakes. QUAL2E is the most useful program in the U.S.A. But it does not fit to small rivers in Korea.And the language,Fortran 77, is uncomfprtable for the users. So I've studied it with Visual Basic in the windows system.

COD/SO₄ 比가 相異한 廢水의 염기성 處理時 動力學에 관한 硏究

趙容璡,全太誠 충주대학교 1990 한국교통대학교 논문집 Vol.24 No.-

A laboratory experiment was conducted in order to develope necessary design paramenters for the anaerobic treatment with different COD/SO₄ratios. The laboratory anaerobic contact diegesters were fed with a synthetic wastewater mainly containing acetic acid. The chemical oxygen demand (DOD) of the wastewater was 2,000 ㎎/L, however the COD/SO₄ratio adjusted to 1.0, 1.7, 2.7, 4.6, and 13.3. An increment of maximum substrate utilization rate(K) and a decrement of half-velocity constant (Ks) were observed at the COD/SO₄ratio of more than 2.7. At the COD/SO₄ratio of 2.7, the largest value of the maximum specific growth rate(u) as well as the smallest value of the minimum mean cell residence time (SRT ??) were observed.

강남성모병원에서의 정신과 자문경험

조용찬,이성필,유태열 大韓神經精神醫學會 1984 신경정신의학 Vol.23 No.2

In an attempt to evaluate the current trends of psychiatric consultation, authors investigated 142 cases of in patients who were referred for psychiatric consultation at Kangnam St. Mary's Hospital from April 1, to November 30, 1983. The results were as follows: 1. The majority of consultations was requested from the department of internal medicine(67.61%). 2. The overall consultation rate was 1.71% of total inpatients for the time period. The department of internal medicine ranked highest in the consultation rate(5.12%). 3. Among the immediate reasons for psychiatric consultation, request for diagnostic evaluation and treatment was 65.63% and request for control of specific symptoms or behavior was 34.37%. 4. Among the somatic symptoms present on consultation, gastrointestinal symptoms and head & CNS symptoms were the most frequent ones. 5. Affective disorders including depression(25.39%), and organic mental disorder(16.58%) were the most frequent diagnostic impressions given by consultant. 6. Regarding the concordance rate with the recommendations given by consultant, absolute concordance with laboratory tests(including psychological tests), drug treatment and psychotherapeutic approach was observed among 62.39% of total consultees. However, non-concordance was observed among 11.93%. 7. For the discharge diagnosis, psychiatric diagnosis was given to 33.03% among all the consultees. 8. The inter-departmental transfer rate following psychiatric consultation was 21.20%.

Dewey의 종교론

조용태,정길영 대구효성가톨릭대학교 교육연구소 1998 교육연구논집 Vol.6 No.-

In examining Dewey’s aesthetic experience with regard to religious experience, this study has found that Dewey’s view of the religion is achieved through aesthetic experience. Dewey insisted humanistic common religion, and opposed any kind of faith which was based on a specific denomination or sect. For Dewey, religious experience, as a nature of experience, can belong to any human experience be it aesthetic, scientific, maral, political, or social. Religious education can be said to realize ideals and values through man’s imagination, and this religious eduation is in accord with general education. Therefore, religious education can be best achieved by realizing their ideals through developing imagination, by having children have aesthetic experiences through providing religious situations. However, in writer’s opinion Dewey’s view about the religion is not religious. Because Dewey did not discuss of Human death, heavenly Kingdom, the Future World, repentance etc., But Dewey’s view to the religious experience is much thinkful to the religious education. The fact, we can feel the divine imagination from the aesthetic experience, in the church’s interior or sacred music or hymns, more than from the sermon of creeds or the supernatural. Dewey rejects such religious education as teaching students to have faith in God, a supernatural and absolute being. In Dewey’s view, religious education in schools should keep children to have religious experience, which lead children to a devotional and meaningful life.