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Sunggu Yeo,Anoop Kumar Srivastava,Hyojin Lee,Ji-Hoon Lee,E-Joon Choi 한국물리학회 2016 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.68 No.2
We investigated the temperature dependences of the dielectric anisotropy, birefringence, order parameter, splay elastic constant, and rotational viscosity of rodlike nematic liquid crystals (RLCs) doped with hockey-stick-shaped liquid crystals (HLCs). Although the order parameter of the HLCRLC mixtures was similar to that of the pure RLC, the dielectric anisotropy and the birefringence of the mixtures were decreased or increased depending on the structure of the HLC molecule. In addition, the activation energies of the mixtures were different, which implies that the intramolecular structure of the HLC molecule had more influence on the electrooptical properties of the HLC-RLC binary mixtures than the inter-molecular interaction between the HLC and the RLC molecules.
이성구(Sunggu Lee),박대종(Daejong Park),권세진(Sejin Kwon) 한국추진공학회 2011 한국추진공학회 학술대회논문집 Vol.2011 No.11
과산화수소와 케로신을 이용한 이원액체추진제 로켓엔진을 위한 산화제 터보펌프를 설계하였으며 수류시험을 통해 설계된 터보펌프의 작동여부를 실험하였다. 과산화수소 터보펌프의 설계조건을 결정하고 펌프의 임펠러를 설계하였다. 펌프를 구동하기 위한 터빈을 차량용 터보차저로 선정하였으며 터빈 맵을 이용하여 가스발생기를 설계하였다. 펌프, 터빈과 가스발생기를 통합하여 터보펌프 시스템을 구축하였으며 수류시험을 통해 터보펌프 시스템이 1.47 bar의 압력으로 3.4 kg/s의 유량을 공급하는 것을 확인하였다. Hydrogen peroxide turbopump was designed for bi-propellant liquid rocket engine using hydrogen peroxide and kerosene as propellants. Turbopump operation was verified through water tests. Design conditions of hydrogen peroxide turbopump were determined, and impeller was designed. Turbine which drives pump was selected from commercial turbocharger. Gas generator was designed by reference from turbine map. Pump, turbine, gas generator were integrated, and turbopump system was constructed. Turbopump supplied water by 1.47 bar of pressure and as well as 3.4 kg/s of mass flow rate.
Ho Gyun Lee,Il Hyeon Jung,Byong Seo Park,Yang Hye Rim,김광곤,Thai Hien Tu,Jung-Yong Yeh,Sewon Lee,Sunggu Yang,Byung Ju Lee,김재근,남궁일성 대한당뇨병학회 2023 Diabetes and Metabolism Journal Vol.47 No.6
Background: Sodium-glucose cotransporter 2 (SGLT-2) inhibitors are currently used to treat patients with diabetes. Previous studies have demonstrated that treatment with SGLT-2 inhibitors is accompanied by altered metabolic phenotypes. However, it has not been investigated whether the hypothalamic circuit participates in the development of the compensatory metabolic phenotypes triggered by the treatment with SGLT-2 inhibitors.Methods: Mice were fed a standard diet or high-fat diet and treated with dapagliflozin, an SGLT-2 inhibitor. Food intake and energy expenditure were observed using indirect calorimetry system. The activity of hypothalamic neurons in response to dapagliflozin treatment was evaluated by immunohistochemistry with c-Fos antibody. Quantitative real-time polymerase chain reaction was performed to determine gene expression patterns in the hypothalamus of dapagliflozin-treated mice.Results: Dapagliflozin-treated mice displayed enhanced food intake and reduced energy expenditure. Altered neuronal activities were observed in multiple hypothalamic nuclei in association with appetite regulation. Additionally, we found elevated immunosignals of agouti-related peptide neurons in the paraventricular nucleus of the hypothalamus.Conclusion: This study suggests the functional involvement of the hypothalamus in the development of the compensatory metabolic phenotypes induced by SGLT-2 inhibitor treatment.