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      • KCI등재후보

        16주간의 자전춤 참여가 중년비만고혈압여성의 관상동맥위험인자에 미치는 영향

        곽정자(Kwak Jung-Ja),김종경(Kim Jong-Kyung),최현민(Choi Hyun-Min),노호성(Nho Ho-Sung) 한국체육과학회 2008 한국체육과학회지 Vol.17 No.2

        It is generally known that cardiovascular and metabolic diseases such as hypertension, diabetes, hyperlipidemia increase morbidity and mortality in postmenopausal women. This study investigated the effects of Jajun-Dance to coronary heart disease of middle age women with hypertension. Thirteen sedentary women (55.8±5.2 yrs) were recruited for this study, and completed 16 weeks of Jajun-Dance program. All subjects were diagnosed as essential hypertension patients. Blood-sugar level (FBG), total cholesterol (TC), triglyceride (TG), systolic blood pressure (SBP), diastolic blood pressure (DBP) and visceral fat area (VFA) were measured. The Jajun-Dance program included 10 minutes warm up (exercise for flexibility), 40 minutes Jajun-Dance, and 10 minutes cool down. The subjects participated in Jajun-Dance program three times a week. Exercise was maintained at exercise intensity corresponding to rating of perceived exertion (RPE) 13-15. The results showed that FBG, SBP, and DBP (6.0 ㎜Hg) were significantly decreased after Jajun-Dance program. TG and VFA tended to decrease, but there were no significant differences. This study suggests that hypertensive middle-aged women could modify coronary risk factors with regular exercise, and that the aerobic Jajun-Dance program could effectively reduce high blood pressure.

      • SCOPUSKCI등재

        Ehlers - Danlos 증후군

        주용진,최성문,최영자,성호석 ( Yoing Jin Joo,Sung Moon Choi,Young Ja Choi,Ho Suk Sung ) 대한피부과학회 1990 대한피부과학회지 Vol.28 No.5

        A Case of Ehlers-Danlos syndrome Yoing Jin Joo, M.D., Sung Moon Choi, M.D., Young Ja Choi*, M.D., Ho Suk Sung, M.D. Department of Dermatology, Clooego of Medicine, Inje University, Pusan, Korea We presented a case of Ehlers-Danlos syndrome in a 25-year old female, who had hyperextensibility of skin, skin fragility, cigarette paper-like atrophic scar, joint hyperextensibility and skeletal abnormality of scoliosis since birth. There was no family history. Microscopic and electron microscopic examinations of the skin biopsy specimens from normal appearing skin on the forearm and the site of subcutaneous nodule was compatible with finding of Ehlers-Danlos syndrome. Although the manifestations of this case including marked extensibility of skin, joint, skin fraility and atrophic scar might be in accord with type Ⅰ(gravis) Ehlers-Danlos syndrome, skeletal abnormality of scoliosis did not correspond to this type, but to type Ⅳ(hydroxylysine deficient) Ehlers-Danlos syndrome. We consider this case as a type Ⅳ Ehlers-Danlos syndrome.

      • 간호대학생의 영적안녕에 관한 연구

        강은실(Kang Eun-Sil),김숙자(Kim Sook-Ja),강성년(Kang Sung-Nyun),최성은(Choi Sung-Eun) 고신대학교 전인간호과학연구소 2008 전인간호과학학술지 Vol.3 No.-

        The purpose of this study was to describe the spiritual well-being of nursing students to provide a basic data for the development the curriculum of Spiritual Nursing Care in nursing collages. The subjects for this study were consist of 58 nursing students in K University of Pusan city in Korea. All of them were educated about Spiritual Nursing Care for 100 minutes in a week, during totally 8 weeks in one semester. The data were collected during 7days from July 11 to July 18,2004 by using structured questionnaire method. The measurement of the spiritual well-being was performed with 6 points-index which is composed of 21 items and is modified by Sang-Soon Choi(1990)from Palau tzian & Ellison(1983) s. Its high score means that the degree of spiritual well-being of the subject is high. The data were analyzed by using the SPSS WIN 10.1 program according to the purpose of this study. The general characteristics of the subjects were analyzed by calculating the real quantity and the percentage, and the spiritual well-being scores were identified through calculating the mean value of individual domain. The significant difference of the general characteristics with the spiritual well-being was analyzed by t-test and ANOVA, Scheffe s test. The results of this study were as follow; 1.The spiritual well-being of the subjects The average value for the spiritual well-being of the subjects was 97.78(SD=±10.53) among the possible ranges of 21-126. The mean value of all items was 4.66(SD=±0.502) and high relatively. 2. The spiritual well-being according to general characteristics of subjects The analysis of the spiritual well-being according to general characteristics of the subjects showed statistically significant difference on the degree of life satisfaction in faith(F=4.327, P= .004),the degree of recognition about God s initiation in their daily life(F=3.933, P= .013),the degree of satisfaction about Nursing as their major(F=6.608, P= .000), their assurance of salvation(t=4.557,P= .037). among the personal religious actions, praising(F=3.32,p= .017), The group of nursing students responded that they were satisfied in their faith life, always God has the initiative in their daily lives personally, they were satisfied about Nursing as their major very much, and they have their assurance of salvation showed the highest degree of the spiritual well-being than any other group. In conclusion, in this study we observed that the spiritual well-being of nursing students was high relatively. The general characteristics of subjects were related to the spiritual well-being of them were the degree of satisfaction in their faith lives,their recognition about God s initiation in their daily life, their satisfaction about Nursing as their major, among the personal religious actions, regular praising and their assurance of salvation. Therefore this study s results can be used for developing a spiritual nursing education and program to strengthen nursing student s spirituality to practice in spiritual nursing care.

      • Load Balancing Methods for RFID Middleware Systems

        Sung-Mee Park,Jeong-Hwan Song,Woo-Yong Choi,Chae-Soo Kim,Jung-Ja Kim 대한전자공학회 2007 ITC-CSCC :International Technical Conference on Ci Vol.2007 No.7

        As RFID systems are widely employed to facilitate data communication in various fields such as supply chain management and inventory control, more and more tag data are generated and need to be processed in real time. If too many data are concentrated on some readers, application systems may not be run properly due to the low data processing throughput of RFID middleware systems. To resolve this problem, the load balancing methods for RFID middleware systems need to be considered. In this paper, we discuss the load balancing methods applicable to RFID middleware systems.

      • SCOPUSKCI등재
      • MHY218-induced apoptotic cell death is enhanced by the inhibition of autophagy in AGS human gastric cancer cells

        CHOI, PYOUNG RAK,KANG, YONG JUNG,SUNG, BOKYUNG,KIM, JAE HYUN,MOON, HYUNG RYONG,CHUNG, HAE YOUNG,KIM, SUNG EUN,PARK, MOO IN,PARK, SEUN JA,KIM, NAM DEUK Spandidos Publications 2015 International journal of oncology Vol.47 No.2

        <P>We previously reported the anticancer effects of MHY218, which is a hydroxamic acid derivative, in HCT116 human colon cancer cells. In the present study, the involvement of autophagy in the MHY218-induced apoptotic cell death of AGS human gastric cancer cells was investigated. MHY218 treatment induced growth inhibition and apoptotic cell death in a concentration- and time-dependent manner. The induction of apoptosis was confirmed by observations of decreased viability, DNA fragmentation, and an increase in late apoptosis and sub-G1 DNA, which were detected with a flow cytometric analysis. Western blot analyses showed that MHY218 treatment resulted in decreased protein levels of procaspase-8, -9, and -3; cleavage of poly(ADP-ribose) polymerase (PARP); and alterations in the ratio of Bax/Bcl-2 protein expression. Apoptosis induced by MHY218 was involved in the activation of caspase-8, -9, and -3, and it was blocked by the addition of Z-VAD-FMK, a pan-caspase inhibitor. In addition, autophagy-inducing effects of MHY218 were indicated by cytoplasmic vacuolation, the accumulation of acidic vesicular organelles, the appearance of green fluorescent protein-light-chain 3 (LC3) punctate dots, and increased levels of Beclin-1 and LC3-II protein expression. Pretreatment with the autophagy inhibitors LY294002, 3-methyladenine, chloroquine, and bafilomycin Al enhanced the induction of apoptosis by MHY218, and this was accompanied by an increase in PARP cleavage. Taken together, these results provide new insights into the role of MHY218 as a potential antitumor agent. The combination of MHY218 with an autophagy inhibitor might be a useful candidate for the chemoprevention and/or treatment of gastric cancer.</P>

      • SCIESCOPUSKCI등재

        PREPARATION OF N-(3-BROMO-2,4,6-TRIMETHYLACETANILIDE)IMINODIACETIC ACID AND ITS ${99M}^TC$-COMPLEX FOR HEPATOBILIARY IMAGING

        CHOI OK-JA,HONG YOUNG-DON,GWON HUI-JEONG,CHOI SANG-MU,CHOI SUN-JU Korean Nuclear Society 2005 Nuclear Engineering and Technology Vol.37 No.4

        N-(3-bromo-2,4,6-trimethylacetanilide)iminodiacetic acid (BrTIDA) was synthesized using nitrilotriacetic anhydride prepared in situ, and lyophilized vials were prepared which contained 20 mg of BrTIDA and 0.4 mg of $SnCl_2$. To evaluate the clinical efficacy of the in-house prepared lyophilized kit, a technetium-99m complex of BrTIDA was prepared; its in vivo pharmacokinetic behavior was evaluated via animal studies to assess the hepatocytic function and the functional status of the cystic duct and the gallbladder. Serial static image scans of rabbits and the biodistribution in mice injected with $^{99m}Tc-BrTIDA$ revealed that none of the tissues except for the hepatobiliary system showed radioactivity concentrations, and a rapid clearance from the organs was observed. In conclusion, a lyophilized kit and its prepared $^{99m}Tc-BrTIDA$ can be applied as a hepatobiliary imaging agent for the evaluation of the functional status of the hepatocytes and the patency of the biliary duct.

      • SCISCIESCOPUS

        The Rates and Clinical Characteristics of Pneumolabyrinth in Temporal Bone Fracture

        Choi, Hyo Geun,Lee, Hyo-Jeong,Lee, Joong Seob,Kim, Dong Hyun,Hong, Sung Kwang,Park, Bumjung,Kim, Si Whan,Kim, Ja Hee,Kim, Hyung-Jong Lippincott Williams Wilkins 2015 Otology & Neurotology Vol.36 No.6

        BACKGROUND: Pneumolabyrinth is a rare inner ear clinical manifestation. To date, only about 50 cases have been reported—all as case reports. Consequently, the rate and clinical characteristics of pneumolabyrinth have not been evaluated. METHODS: Of the 38, 568 patients who visited our emergency department for head trauma, 466 underwent temporal bone computed tomography (CT). One hundred seventy-five patients had temporal bone fracture (13 bilateral temporal bone fractures; 188 ears with temporal bone fractures), and 14 patients had pneumolabyrinth (15 ears with pneumolabyrinth; 1 bilateral case). A retrospective review of their medical records and radiologic findings was performed. Temporal bone fractures were classified by two different systems: the traditional classification and an otic capsule–based classification. RESULTS: Pneumolabyrinth occurred in 8.0% of all temporal bone fractures, 4.0% of longitudinal temporal bone fractures, 16.1% of transverse or mixed temporal bone fractures, and 48.4% of otic capsule–violating temporal bone fractures. In all cases, pneumolabyrinth was found on CT, which was performed within 3 days, but not on follow-up CT performed 5 days or longer after head trauma. All patients complained of hearing loss and dizziness. Hearing in most patients (83.3%) did not improve, whereas dizziness improved in 91.7% of patients. Air was located only in the vestibule or semicircular canal in 53.3% and in the vestibular or semicircular canal and cochlea in 46.6% of ears with pneumolabyrinth. The initial hearing threshold and recovery rate using pure-tone audiometry were not different according to the air location in the inner ear. CONCLUSION: Pneumolabyrinth was more common than expected; we believe that the timing of evaluation affects its rarity. Pneumolabyrinth was detected in nearly 50% of patients with otic capsule–violating temporal bone fractures when CT scanning was performed early after trauma.

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