중국 연변 조선족자치주 성인과 한국 구리지역 성인의 식생활 양식 비교

이선희,백희영,김정순,문용,정효지 한국식생활문화학회 2001 韓國食生活文化學會誌 Vol.16 No.4

This study was conducted to investigate dietary patterns and assimilation of dietary culture of Korean descendants in Yanbian, China compared to Korean. A dietary survey was conducted using one 24-hour recall method from 730 adults over 30 years of age in Yanbian, China and 695 adults over 25 years of age in Kuri, Korea. The average number of food items consumed per day was 14 in Yanbian and 20 in Kuri and there was a significant difference between the two regions(p<0.001). The foods consumed most frequently were rice, salt, the M.S.G. in Yanbian and rice, green onion and garlic in Kuri. The foods consumed most by amount were rice, cucumber, Soju in Yanbian and rice, Kimchi and grape in Kuri. The average number of dishes consumed per day was 6.4 in Yanbian, 9.4 in Kuri and the difference between the two regions was significant(p<0.001). Total number of dishes appeared in the survey was 253 in Yanbian and 494 in Kuri. The dishes consumed most frequently were cooked-rice, beverages, Kimchi, stir-fried eggplant in Yanbian and cooked-rice, Kimchi, coffee, soybean paste stew, in Kuri. The dish groups appeared most frequently were rice, stir-fried foods, vegetables and Kimchi in Yanbian and rice, Kimchi, beverages and fruits in Kuri. Male subjects in Yanbian Consumed alcohol frequently while adults in Kuri consumed coffee more frequently than Yanbian. The major meal patterns were rice+side dish, rice+soup, rice+side dish+Kimchi in Yanbian and rice+soup+side dish+Kimchi, rice+side dish+Kimchi, rice+soup+Kimchi in Kuri. Stir-fried foods, which were consumed 46.6% of all the meals, were dominant side dish in Yanbian, but stir-fried food, seasoned vegetables and grilled food appeared aver 10% in Kuri. There results show that variety of diet of Korean-Chinese in Yanbian was lower than Kuri. Korean-Chinese tend to keep traditional Korean dietary patterns of consuming rice as staple but were adapted to Chinese dietary patterns of consuming stir-fried side dishes. Efforts should be directed toward preserving Korean traditional patterns of dietary culture among Korean-Chinese population.

Design and applications of fluorescent detectors for peroxynitrite

Wang, Shan,Chen, Liyan,Jangili, Paramesh,Sharma, Amit,Li, Wei,Hou, Ji-Ting,Qin, Caiqin,Yoon, Juyoung,Kim, Jong Seung Elsevier 2018 Coordination Chemistry Reviews Vol.374 No.-

<P><B>Abstract</B></P> <P>Peroxynitrite (ONOO<SUP>−</SUP>) is one of the endogenous reactive oxygen species (ROS), which causes damage to a wide array of molecular components in the cells, including DNA and proteins, owing to its high oxidizing as well as nitrating properties. However, the precise pathogenic roles played by this substance in biological systems have not yet been elucidated completely owing to its short lifetime, high reactivity, low concentration and elusive nature in the <I>in vivo</I> applications. Thus, the development of more sensitive and selective techniques for detecting ONOO<SUP>−</SUP>, with high biocompatibilities, sensitivities, and site-specificities, is a significant goal. This review summarizes the recent advances that have been made in developing fluorescent sensors for ONOO<SUP>−</SUP> and their biological applications in diverse living systems.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The general significance of ONOO<SUP>−</SUP> detection. </LI> <LI> The design strategies of functional ONOO<SUP>−</SUP> probes. </LI> <LI> The diverse platforms to design ONOO<SUP>−</SUP> probes, including small molecules, proteins and nanocarriers. </LI> <LI> The diverse biological applications of fluorescent ONOO<SUP>−</SUP> probes. </LI> <LI> Perspectives and potential future directions. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>In this review, the development of fluorescent probes for peroxynitrite detection since 2013 is described. The chemical sensor’s designs has been classified by their reaction based sensing patterns.</P> <P>[DISPLAY OMISSION]</P>

Release dynamics of As, Co, and Mo in a biochar treated soil under pre-definite redox conditions

El-Naggar, Ali,Shaheen, Sabry M.,Hseu, Zeng-Yei,Wang, Shan-Li,Ok, Yong Sik,Rinklebe, Jö,rg Elsevier 2019 The Science of the total environment Vol.657 No.-

<P><B>Abstract</B></P> <P>This study assessed the impact of pre-definite redox potential (E<SUB>H</SUB>) on the release dynamics and distribution of As, Co, and Mo between the dissolved and colloidal phases as well as their potential mobility and phytoavailability in the sediment phase of a mining soil treated with rice hull biochar (BC). The experiment was conducted from controlled moderately-reducing to oxidizing conditions using an automated biogeochemical microcosm system. Arsenic and Mo were more abundant in the dissolved phase due to their predominant in potential mobile fractions, while Co was more abundant in the colloidal phase due to its association with Fe-(hydr)oxides. Biochar increased the dissolved and colloidal concentrations of As, the dissolved concentration of Co, and the colloidal concentration of Mo under oxidizing condition. On the other hand, the application of BC decreased the dissolved concentration of Mo and the colloidal concentration of Co in the first redox cycle under reducing-acidic condition, due to lower pH values, and chemistry of sulfide-sulfate and Fe/Mn oxides. The phytoavailability of As and Co were higher than their potential mobility in the sediment phase, while the same trend was not discerned for Mo. The potential mobility and phytoavailability of As and Co were high under oxic-acidic conditions. The potential mobility and phytoavailability of Mo might be increased under oxic condition due to the dissolution of Fe and Mn oxides under lower pH conditions, especially in the BC treated soil. Application of such rice hull BC to soil might stimulate the release of As, Co, and Mo under flooding conditions, which might increase the environmental and health risks in such wetland ecosystems.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The E<SUB>H</SUB> showed a converse relation with pH in biochar treated and non-treated soils. </LI> <LI> Arsenic and Mo were abundant in the dissolved phase, but Co in the colloidal phase. </LI> <LI> Biochar increased the dissolved As and Co under oxidizing conditions. </LI> <LI> Biochar decreased the dissolved Mo under acidic conditions in the first redox cycle. </LI> <LI> Potential mobility and phytoavailability were higher under low pH and high E<SUB>H</SUB>. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Systematic Functional Annotation of Somatic Mutations in Cancer

Ng, Patrick Kwok-Shing,Li, Jun,Jeong, Kang Jin,Shao, Shan,Chen, Hu,Tsang, Yiu Huen,Sengupta, Sohini,Wang, Zixing,Bhavana, Venkata Hemanjani,Tran, Richard,Soewito, Stephanie,Minussi, Darlan Conterno,Mo Cell Press 2018 CANCER CELL Vol. No.

<P><B>Summary</B></P> <P>The functional impact of the vast majority of cancer somatic mutations remains unknown, representing a critical knowledge gap for implementing precision oncology. Here, we report the development of a moderate-throughput functional genomic platform consisting of efficient mutant generation, sensitive viability assays using two growth factor-dependent cell models, and functional proteomic profiling of signaling effects for select aberrations. We apply the platform to annotate >1,000 genomic aberrations, including gene amplifications, point mutations, indels, and gene fusions, potentially doubling the number of driver mutations characterized in clinically actionable genes. Further, the platform is sufficiently sensitive to identify weak drivers. Our data are accessible through a user-friendly, public data portal. Our study will facilitate biomarker discovery, prediction algorithm improvement, and drug development.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Developed a versatile functional genomic platform for somatic mutation annotation </LI> <LI> Annotated >1,000 genomic aberrations, doubling the number of known driver mutations </LI> <LI> Assessed performance of existing algorithms for mutation functional predictions </LI> <LI> Built a user-friendly, open-access data portal for community-based investigation </LI> </UL> </P> <P><B>Graphical Abstract</B></P> <P>[DISPLAY OMISSION]</P>

Synthesis and Characterization of Lactobionic Acid Grafted Phenylalanyl-Glycyl-Chitosan

Li, He-Ping,Li, Shan,Wang, Zhou-Dong,Qin, Long Korean Chemical Society 2011 대한화학회지 Vol.55 No.6

In order to enhance the target action of chitosan-based drug, this paper firstly prepared phenylalanyl-glycylchitosan (Phe-Gly-CS) by grafting the key intermediate, bromoacetyl-phenylalanine (BA-Phe) onto chitosan. Then the target sugar molecule, lactobionic acid (LA), was grafted to Phe-Gly-CS and the topic compound lactobionic acid grafted phenylalanyl-glycyl-chitosan (Phe-Gly-CS-LA) was finally obtained in a yield of 78.8%. The product were characterized by FTIR, MS and 1H NMR. The preparing condition of BA-Phe was optimized as follows: the best pH was 10-11, the optimum temperature was $-4^{\circ}C$, the reaction time was 1.5 h.

The development of differential inductors using double air-bridge structure based on integrated passive device technology

Li, Y.,Yao, Z.,Fu, X.Q.,Li, Z.M.,Shan, F.K.,Wang, C. Pergamon Press ; Elsevier Science Ltd 2017 Solid-state electronics Vol.131 No.-

Recently, integrated passive devices have become increasingly popular; inductor realization, in particular, offers interesting high performance for RF modules and systems. In this paper, a development of differential inductor fabricated by integrated passive devices technology using a double air-bridge structure is presented. A study of the model development of the differential inductor is first demonstrated. In this model section, a segment box analysis method is applied to provide a clear presentation of the differential inductor. Compared with other work that only shows a brief description of the process, the integrated passive devices process used to fabricate the inductor in this study is elaborated on. Finally, a characterization of differential inductors with different physical layout parameters is illustrated based on inductance and quality factors, which provides a valuable reference for realizing high performance. The proposed work provides a good solution for the design, fabrication and practical application of RF modules and systems.

Graphene Quantum Dots Enhanced Photocatalytic Activity of Sb2WO6 Under Ultraviolet- and Visible-Light Irradiation

Shan Li,Zhongping Chen,Datong Wu,Yong Qin,Yong Kong 대한화학회 2020 Bulletin of the Korean Chemical Society Vol.41 No.5

A novel composite of graphene quantum dots functionalized Sb2WO6 (GQDs/Sb2WO6) was prepared by an electrostatic self-assembly method and used as a photocatalyst for the degradation of an organic pollutant. The resulting GQDs/Sb2WO6 was characterized by electron microscopy and optical measurements. The photocatalytic activity of GQDs/Sb2WO6 was investigated by degrading methyl orange (MO) under UV-light and visible-light irradiation. Compared with pure Sb2WO6, enhancement of the photocatalytic performance of GQDs/Sb2WO6 was achieved, and the degradation efficiency for MO was almost 100% within 3 h under UV-light irradiation and 71.4% within 3 h under visible-light irradiation. The photocatalytic degradation mechanism of GQDs/Sb2WO6 was illustrated by free radical and hole scavenging experiments, and the main active species were confirmed to be holes (h+) and superoxide anion radicals (O2·?). Moreover, the GQDs/Sb2WO6 composites exhibited high recyclability and stability and had potential application for decomposing other organic contaminants in water.

Affective Decision-Making among Preschool Children in Diverse Cultural Contexts

Li Qu,Gao Shan,Cindy Yip,Hong Li,Philip David Zelazo 한국아동학회 2012 Child studies in Asia-Pacific context Vol.2 No.2

The current study examined 3- and 4-year-olds` affective decision-making in a variety of cultural contexts by comparing European Canadian children to Chinese Canadian, Hong Kong Chinese, and mainland Chinese children (N = 245). All children were tested with a delay of gratification task in which children chose between an immediate reward of lower value and a delayed reward of higher value. Results showed that Chinese Canadian and Hong Kong Chinese children chose more delayed rewards than European Canadian children, with mainland Chinese children showing a trend toward more delayed rewards. Across cultures, 4-year-olds chose more delayed rewards than 3-year-olds; and among 4-year-olds, girls made more such choices than boys. The findings are consistent with previous findings that exposure to Chinese culture is associated with better cool executive function, but they also highlight the importance of examining development across diverse cultural contexts.

Chemoresistance in ovarian cancer: exploiting cancer stem cell metabolism

Shan-Shan Li,Jing Ma,Alice S. T. Wong 대한부인종양학회 2018 Journal of Gynecologic Oncology Vol.29 No.2

Ovarian cancer is most deadly gynecologic malignancies worldwide. Chemotherapy is the mainstay treatment for ovarian cancer. Despite the initial response is promising, frequent recurrence in patients with advanced diseases remains a therapeutic challenge. Thus, understanding the biology of chemoresistance is of great importance to overcome this challenge and will conceivably benefit the survival of ovarian cancer patients. Although mechanisms underlying the development of chemoresistance are still ambiguous, accumulating evidence has supported an integral role of cancer stem cells (CSCs) in recurrence following chemotherapy. Recently, tumor metabolism has gained interest as a reason of chemoresistance in tumors and chemotherapeutic drugs in combination with metabolism targeting approaches has been found promising in overcoming therapeutic resistance. In this review, we will summarize recent studies on CSCs and metabolism in ovarian cancer and discuss possible role of CSCs metabolism in chemoresistance.

A New Dammarane-type Triterpene with PTP1B Inhibitory Activity from Gynostemma pentaphyllum

Li, Na,Tuo, Zhen-Dong,Xing, Shan-Shan,Qi, Shi-Zhou,Lee, Hyun-Sun,Cui, Long Korean Chemical Society 2014 Bulletin of the Korean Chemical Society Vol.35 No.10